Opinion: The psychedelic revolution is leaving behind people of color

Flanked by one of psychedelics’ biggest celebrity cheerleaders, Joe Rogan, and a troupe of MAHA loyalists, President Trump recently signed an executive order aimed at accelerating psychedelic access for clinical research and treatment.

Use of naturally occurring and synthetic hallucinogens traces back to the Neanderthals. Yet these substances have long been a pariah in mainstream medicine, written off as “club drugs” with little to no clinical value (or worse, downright negative effects).

Read the rest…

Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression

Conditions: Major Depression

Interventions: Drug: D-Cycloserine (DCS); Device: Continuous theta-burst stimulation (cTBS); Device: Transcranial Magnetic Stimulation Sham; Drug: Memantine; Drug: Lorazepam (drug); Drug: Baclofen; Drug: Placebo

Sponsors: Mclean Hospital; National Institute of Mental Health (NIMH)

Recruiting

Inhaled DMT for Major Depressive Disorder

Conditions: MDD; Major Depressive Disorder (MDD); Major Depression; Suicidal Ideation; Suicide

Interventions: Drug: N,N-Dimethyltryptamine (15 mg + 60 mg); Drug: N,N-Dimethyltryptamine (1 mg + 4 mg)

Sponsors: Universidade Federal do Rio Grande do Norte; Financiadora de Estudos e Projetos

Not yet recruiting

Develop and Evaluate An Artificial Intelligence Assisted Prehabilitation Program for Returning to Work and Cost-effectiveness Analysis in Patients With Oral Cancer

Conditions: Oral Cancer; Psychological Distress; Communication Aids for Disabled; Physiotherapy; Return to Work; Prehabilitation; Physical Symptom Distress; Motor Function; Rehabilitation; Quality of Life; Cost Effectiveness; Artifical Intelligence; Prediction Model; Case Management, APP(Application)

Interventions: Device: Prehabilitation application; Behavioral: Conventional physiotherapy; Behavioral: Scar management; Behavioral: AI-based physiotherapy

Sponsors: Taipei Veterans General Hospital, Taiwan; National Taiwan University Hospital; National Yang Ming Chiao Tung University Hospital

Recruiting