Oral and Sublingual Ketamine

Conditions: Major Depression Severe

Interventions: Drug: 75 mg of oral ketamine; Drug: Sublingual ketamine 75 mg

Sponsors: Western University, Canada

Not yet recruiting

Pregnenolone for Cannabis Use Disorder and Depression

Conditions: Cannabis Use Disorder; Major Depressive Disorder (MDD)

Interventions: Drug: Pregnenolone

Sponsors: University of Texas Southwestern Medical Center; National Institute on Drug Abuse (NIDA); The University of Texas at Dallas

Not yet recruiting