Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

Conditions: Opioid-Induced Respiratory Depression; Postoperative Complications (Cardiopulmonary); Respiratory Complications Due to Anesthesia

Interventions: Device: Infrared Pupillometry

Sponsors: NeurOptics Inc; National Institute on Drug Abuse (NIDA); University of Pittsburgh Medical Center; University of California, San Francisco

Not yet recruiting

Allopurinol in Depression

Conditions: Depression

Interventions: Drug: Sertraline 50 MG; Drug: Allopurinol 300 MG

Sponsors: Tanta University

Not yet recruiting

tDCS: Sleep to Mood in Depression (S2M-D)

Conditions: Major Depressive Disorder; MDD; Depression; Major Depressive Episode

Interventions: Device: transcranial direct current stimulation (tDCS)

Sponsors: NYU Langone Health; Zabara Foundation

Not yet recruiting

Evaluating the Impact of Ketogenic Therapy on Symptom Severity and Metabolic Side Effect Profile Among Individuals Living With Bipolar Disorder in A Rural Southern Catchment Area

Conditions: Bipolar Disorder

Interventions: Dietary Supplement: Ketogenic foodstuffs; Other: Standard of Care Oral antipsychotics; Other: Standard of care long acting injectable medication for bipolar disorder

Sponsors: University of Alabama at Birmingham; Baszucki Family Foundation; Baptist Health System Montgomery

Not yet recruiting

Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)

Conditions: Borderline Personality Disorder (BPD); Treatment-Resistant Major Depressive Disorder; Treatment-resistant Bipolar Depression; Major Depressive Disorder (MDD); Bipolar Disorder (BD); Bipolar Disorder I or II; Suicidal Ideation

Interventions: Drug: Ketamine Hydrochloride; Drug: Midazolam Hydrochloride; Behavioral: Dialectical Behavioral Therapy (DBT)

Sponsors: Joshua Rosenblat

Not yet recruiting