Nature Biotechnology, Published online: 27 May 2026; doi:10.1038/s41587-026-03112-5
SIGnature enables scalable cross-dataset analyses by combining explainable artificial intelligence with RNA foundation models.
Nature Biotechnology, Published online: 27 May 2026; doi:10.1038/s41587-026-03112-5
SIGnature enables scalable cross-dataset analyses by combining explainable artificial intelligence with RNA foundation models.
CDMO WuXi Vaccines, a wholly-owned subsidiary of WuXi Biologics, reports that its drug substance facility (MFG23) located in Suzhou, China, has received GMP certification from Brazil’s Agência Nacional de Vigilância Sanitária (ANVISA). The facility provides integrated manufacturing services for Instituto Butantan’s dengue vaccine (Butantan-DV) production project.
“The GMP certification of our DS facility, our second certification from ANVISA, represents a pivotal step in advancing our dengue vaccine project with Instituto Butantan and establishing a solid foundation to deliver on our shared commitment to expand access to high-quality dengue vaccines,” said Jian Dong, CEO of WuXi Vaccines. “Adhered to premier quality standards and powered by our integrated solutions and technologies, we remain committed to driving greater access to safe, effective, and affordable vaccines worldwide.”
Based on the commercial manufacturing agreement with Instituto Butantan and Fundação Butantan, WuXi Vaccines will provide end-to-end services, including drug substance and drug product manufacturing and quality control for the 5-dose dengue vaccine, according to Dong. The partnership plans to rapidly scale up vaccine capacity, aiming to deliver millions of doses to shield Brazil’s population from dengue. In November 2025, the single-dose Butantan-DV received ANVISA approval for use with individuals aged 12 to 59.
The post WuXi’s Facility in China Receives Brazilian GMP Certification for Dengue Vaccine Manufacturing appeared first on GEN – Genetic Engineering and Biotechnology News.
Storytelling is core to humanity’s DNA, stemming from our impulse to express ideals, warnings, hopes, and experiences. Technology has always been woven through the medium and the distribution: from early humans’ innovation of natural pigments and charcoals for cave paintings to literal representation by the camera.

The landscape of storytelling continues to shift under our feet. Social and streaming platforms have multiplied, audiences have fragmented, and our demand for fresh, unique media is insatiable. A recent McKinsey podcast cites that we are watching upwards of 12 hours of video content daily, often on multiple devices and multiple platforms.
All this content is expensive to produce: With a baseline budget of $150M, a Hollywood feature runs $1M per minute of finished film; prestige streaming content is in the hundreds of thousands per minute. And since consumers want to engage with authentic, original material, every company is now effectively a media company. That means we all face the same pressure: more content, with the same time and budget constraints.
There is no longer a question whether to use AI for content; the math doesn’t work any other way. What leaders need to focus on now is how to adapt responsibly, protect brand integrity, uplift team creativity, and build customer trust.
A few things worth holding onto as this era accelerates:
Creative teams are trapped on the endless hamster wheel of production, and it’s not slowing down. According to Adobe research, content demand will grow 5x over the next two years. Social content shelf life is now measured in hours, not weeks. Keeping fresh work in the pipeline is a permanent sprint, requiring teams to rethink how creative production functions.
The first move is freeing creative teams by having AI absorb the repetitive work so they have space for the strategic creative decisions that require human ingenuity. In a recent study from Adobe, 94% of creatives report that AI helps them produce content faster, saving an average of 17 hours per week. That recovered time is not a productivity metric; it is renewed creative capacity.
As a use case, Nestlé offers a useful blueprint. Its teams operate across 180 countries with a portfolio of iconic brands including Nescafé, KitKat, and Purina. Using Adobe Firefly Custom Models embedded in existing content workflows allows teams to generate assets in a brand-informed style without disrupting creative flow. At Nestlé, workflow cycle times dropped 50%. “With Firefly Custom Models, we can react at the speed of culture. It’s the closest thing we’ve had to magic.” says Wael Jabi, global strategic comms lead for KitKat.
As we move into the agentic era, the possibilities expand further. Adobe’s Creative Agent thinks in systems, not tasks, orchestrating across workflows, apps, and processes to close the gap between idea and execution, and get teams out of the production cycles that consume their productivity.
A company’s brand is how the world recognizes and connects with them. And it’s more than a collection of assets—it is dynamic, subjective, and expressed in thousands of micro-decisions made every day by the people who know it best. As production scales, keeping everything tuned to the brand gets more challenging. Off-the-shelf AI cannot replicate the level of nuance creative teams bring to content, and there’s a real cost to getting it wrong; diluting a brand in market with almost-right output is not an acceptable option. Customer trust is fragile.
Starting with a bespoke AI model built with Adobe Firefly Foundry addresses this directly. Firefly Foundry starts with a commercially safe base model and trains further on a company’s IP, making it possible to produce content that genuinely reflects the team’s vision.
And to ensure that Firefly Foundry models truly represent the creatives at the helm, Adobe has partnered with film studios like Wonder Studios, Promise.ai, and B5 Studios, and the “big three” talent agencies CAA, UTA, and WME to deeply understand what it means (and what it takes) to build an IP-immersive model that keeps creatives at the center as these film studios and talent agencies scale their visions. These brand ecosystems can accelerate nearly every phase of the production process, from ideation and storyboarding to production and promotion, all while preserving artistry and authorship. And to power the next generation of creativity and content, Adobe has recently announced a strategic partnership with NVIDIA, delivering best-in-class creative control along with enterprise-grade, commercially safe content at scale.
Generic AI gives teams a starting point. But a model trained on a brand’s own IP gets them to the finish line, while still leaving room for the creative calls that matter most.
AI is not only reshaping how we create; it is reshaping how customers find and engage with brands entirely. According to Adobe Digital Insights, AI-powered shopping has surged 4,700%. Agentic web traffic is up 7,851% year over year. Yet, most businesses still have significant gaps in AI-led brand visibility. If content is invisible to AI agents, then a brand is invisible to customers.
Major League Baseball is ahead of this curve. Using Adobe LLM Optimizer, the league monitors how its content surfaces across AI interfaces and makes real-time adjustments to maintain visibility. As fans search for tickets, stats, or game-day experiences, the league ensures its brand shows up wherever that search is happening. And with Adobe’s recent acquisition of Semrush, brand visibility goes even further.
The agentic web created an entirely new content surface that did not exist two years ago, and this exponential proliferation of content illustrates precisely why scaled, on-brand content production has become a strategic imperative. A well-built agentic foundation offers full visibility into (and control over) every piece of content, from production to performance.
Here are a few steps to get started:
Audit before automation. Content supply chains usually include duplicated processes, unclear ownership, and assets living in many different places. Before AI can accelerate anything, develop a clear map of how content moves through the organization today: who creates it, who approves it, where it lives, and where it breaks down. AI applied to a broken process just breaks it faster.
Walk through workflows. Resist the urge to overhaul everything at once. Start with production tasks that are high-volume, low-stakes, and well-defined: asset resizing, localization, and background generation. Use those wins to build internal confidence before expanding into more complex creative territory.
Build responsible governance from the start. Governance added as an afterthought becomes a bottleneck. Building it in from the beginning creates a competitive advantage that lets teams move fast with confidence. And this means clear policies on model training, content provenance, human review thresholds, and communicating AI use to customers. The brands that earn lasting trust will treat transparency as a feature, not a footnote.
This content was produced by Adobe. It was not written by MIT Technology Review’s editorial staff.
Listen to the session or watch below
Elon Musk lost his suit against OpenAI, in which he alleged CEO Sam Altman and President Greg Brockman had deceived him over the company’s non-profit status.
Watch as AI reporter and attorney Michelle Kim, who covered the trial for MIT Technology Review, joins in conversation with editor in chief Mat Honan to go behind the scenes of the trial and the implications for the AI race.
Speakers: Mat Honan, Editor in Chief, and Michelle Kim, AI Reporter
Recorded on May 19, 2026
Related Stories:
Background: Positive aging, a concept found in positive psychology, serves as the theoretical foundation for this study. To age positively, one must manage hidden or unrecognized challenges, show flexibility in behavior and thought, adopt a positive outlook on problems involving regression, and make decisions that promote one’s well-being. Objective: This study examined the role of wisdom and life purpose in the mental well-being of middle-aged and older adults. More specifically, we tested 4 hypotheses: wisdom would exhibit a positive correlation with mental well-being, quality of life would exhibit a positive correlation with mental well-being, meaning and purpose would exhibit a positive correlation with mental well-being, and freedom would exhibit a positive correlation with mental well-being. Methods: The research used a multianalytical methodology combining covariance-based structural equation modeling and artificial neural network techniques to analyze data from 377 individuals aged 50 to 102 years. Results: Results from the covariance-based structural equation modeling indicate that meaning and purpose, wisdom, and quality of life were significantly associated with the mental well-being, accounting for 71% of the explained variance. Additionally, the artificial network analysis yielded exact forecasts of mental well-being. The artificial network model achieved an accuracy of 82.1% and 73% on the training and test sets, respectively, for predicting mental well-being. Sensitivity analysis revealed that meaning and purpose were the most critical factors in explaining participants’ mental well-being. Conclusions: These findings have prominent theoretical implications for social psychology researchers and practical consequences for authorities involved in the care of older adults, who can use the results to develop strategic plans and take necessary actions.
<img src="https://jmir-production.s3.us-east-2.amazonaws.com/thumbs/bcaa6f908281d20d0d1f9e2fe7fc5e52" />
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology.
Elon Musk has lost his lawsuit against OpenAI, which centered on whether the company breached its founding contract as a nonprofit. A jury found that he sued too late, meaning his claims are barred by statutes of limitations. But the verdict didn’t judge if OpenAI violated its nonprofit mission—only whether Musk brought the case in time.
The dispute centers on when OpenAI began shifting toward a for-profit structure. The company argued that signs of a shift were visible as early as 2017, while Musk said he only discovered the change in 2022.
—Michelle Kim
Join us later today for a subscriber-only Roundtables discussion about what happened in the courtroom and what the verdict means for OpenAI and the larger AI race. Register here.
The defense-tech company Anduril has shared new details about the augmented-reality headset for the military it’s prototyping with Meta, including a vision for ordering drone strikes via eye-tracking and voice commands.
Quay Barnett, who leads the effort at Anduril following a career in the Army’s Special Operations Command, says he aims to optimize “the human as a weapons system.” Find out how he plans to do it—and what smart glasses could mean for warfare.
—James O’Donnell
When Google opens its doors today for its annual developer conference, I/O, it will do so as a clear third place in the foundation model race.
A foundation model’s reputation these days rests largely on its coding capabilities, and for months Google’s coding tools have been outgunned by Anthropic’s Claude Code and OpenAI’s Codex. But the company still shapes the cutting edge in areas such as AI for science. At I/O this week, it will try to prove it can compete on both fronts.
I’m going to be at Mountain View this week to see what goes down. Here are three things to keep a close eye on.
—Grace Huckins
This story is from The Algorithm, our weekly newsletter giving you the inside track on all things AI. Sign up to receive it in your inbox every Monday.
As the limits of LLMs become clearer, researchers are developing a new kind of AI designed to understand the physical environment: world models.
Recent developments from Google DeepMind, Fei-Fei Li’s World Labs, and Yann LeCun’s new startup have pushed these systems to the forefront of AI. At an upcoming virtual event, MIT Technology Review will examine the progress—and what comes next.
On Thursday, May 21, editor in chief Mat Honan, senior AI editor Will Douglas Heaven, and AI reporter Grace Huckins will take part in an exclusive Roundtables discussion on world models. Register here to join the session at 19:30 GMT / 2:30 PM ET / 11:30 AM PT.
World models are one of our 10 Things That Matter in AI Right Now, a new guide to the technologies and ideas shaping the future of AI.
The must-reads
I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.
1 OpenAI’s legal win over Elon Musk clears its path to a blockbuster IPO
The jury’s verdict was a critical moment for the company’s future. (Reuters $)
+ The trial spilled plenty of dirt about Silicon Valley. (MIT Technology Review)
+ And added to concerns about AI’s leadership. (The Verge)
2 Google and Blackstone are launching a new AI cloud company
The venture will use Google’s specialized chips. (Bloomberg $)
+ It aims to mount a challenge to Nvidia. (FT $)
+ Blackstone is investing $5 billion in the company. (WSJ $)
3 Meta is reshaping its workforce around AI while preparing deep layoffs
It’s reassigning 7,000 employees to four new AI-focused groups. (NYT $)
+ And plans to lay off 10% of its staff on Wednesday. (Reuters $)
+ More cuts are expected later this year. (CNBC)
4 The Iran conflict is straining the AI supply chain
TSMC, Foxconn, and Infineon have felt major disruption. (CNBC)
+ The war also threatens a vital water technology. (MIT Technology Review)
5 China’s AI-powered brain implants are moving to real-world use
Some devices will soon be sold to the public. (Nature)
+ BCIs now must be proven as products. (MIT Technology Review)
6 A US cybersecurity agency exposed its own digital keys on GitHub
A researcher said it’s the worst leak he’s ever seen. (Krebs on Security)
+ The culprit was the CISA, a relatively new branch of the DHS. (Gizmodo)
7 Supercharging immune cells may help control HIV long-term
CAR-T cell therapy is showing promise for managing HIV. (Wired $)
8 Filipino virtual assistants are powering “thought leadership” on LinkedIn
Low-paid workers use AI to write posts for Western executives. (Rest of World)
9 Big Four accounting firms have more job ads for AI staff than auditors
Accounting giants are rushing to adapt to technological disruption. (FT $)
10 Tech founders are being sent to etiquette school
In the AI era, soft skills may matter more than ever. (WSJ $)
Quote of the day
—President Trump tells Fortune that he should have requested a greater share of Intel than the 10% stake that the US government received.
One More Thing
On a kayak trip through a Connecticut salt marsh, plastic waste appears almost immediately. There are bags in reeds, bottles in the water, and tiny pieces scattered everywhere. What looks like a pristine ecosystem is already saturated.
Plastic is produced at enormous scale but rarely recycled. Instead, it breaks apart into microplastics, which are now detected across the environment and in human bodies.
Read the full story on why plastic pollution is so hard to contain.
—Douglas Main
We can still have nice things
A place for comfort, fun, and distraction to brighten up your day. (Got any ideas? Drop me a line.)
+ Discover the beauty hidden within numbers at this charming site.
+ Find out how many millions of miles you’ve traveled through space since birth.
+ An extraordinary image has captured the split-second the ISS silhouetted itself against the Moon.
+ The most insane megaproject you’ve never heard of tried to turn atomic bombs into peaceful construction tools.