Interventions: Other: Light therapy using active glasses; Other: Light therapy using inactive glasses
Sponsors: Centre Hospitalier Annecy Genevois; Direction Générale de la Santé, France; Association France REIN; LUCIMED
Not yet recruiting
Samsung Biologics made an all-cash public tender offer of approximately $1.8 billion to acquire Switzerland-based PolyPeptide Group, a CDMO specializing in peptide-based active pharmaceutical ingredients (APIs).
Samsung views the deal as expanding its capabilities beyond antibodies and ADCs to include peptide therapeutics, particularly in obesity and diabetes, including GLP-1 therapies, while advancing innovation across high-growth areas such as oncology and other emerging indications. The transaction brings together Samsung Biologics’ global manufacturing scale with PolyPeptide’s specialized peptide expertise to create a differentiated, end-to-end multi-modality CDMO platform, notes a Samsung spokesperson.
PolyPeptide operates an integrated development-to-commercial model with growth focused on a modular, automation approach which, the company points out, gives it the flexibility to adapt quickly to changing market demand.
The planned acquisition extends beyond adding capacity in that it also lays the foundation for Samsung Biologics’ next phase of growth, supported by a strong pipeline of active peptide projects that includes a deep late-stage portfolio, notes a Samsung official. PolyPeptide operates global sites across Sweden, Belgium, France, the U.S., India, together with a corporate office in Switzerland and a separate Innovation Center in Strasbourg, France, with capabilities in R&D, development, and commercial manufacturing.
Upon completion of the transaction, Samsung will bring together PolyPeptide’s experienced team and specialized peptide expertise with Samsung’s scientific and manufacturing strengths and global operations, says John Rim, chairman of the board of directors and CEO of Samsung Biologics.
“This acquisition reinforces our long-term growth strategy by not only broadening our service portfolio with modality expansion into peptides including GLP-1, but by also boosting our geographic reach and proximity further within the U.S., Europe, and India,” continues Rim.
“After a comprehensive review of strategic options, the Board is convinced that Samsung Biologics’ offer is compelling for our shareholders, delivering an attractive cash price and immediate, certain value today,” adds Peter Wilden, chairman of the board of directors of PolyPeptide. “At the same time, it represents a transformational opportunity to accelerate our strategic ambitions at a scale we could not reach alone.”
The post Samsung Proposes Offer to Acquire Swiss CDMO Specializing in Peptides appeared first on GEN – Genetic Engineering and Biotechnology News.
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology.
When NASA’s Nancy Grace Roman Space Telescope launches, as early as the end of next month, it will attempt one of astronomy’s most precise disappearing acts to date. It will carry the first space-bound “active” coronagraph, an instrument that effectively erases most of the light from a star during photography.
The technology will allow astronomers to take the first pictures of planets orbiting other stars that are similar to those in our solar system. Ultimately, it could pave the way for a future mission that could snap the first photos of Earth-like worlds.
“I hope it’s remembered for it being that critical stepping stone for … finding Earth 2.0,” says Brandon Creager, the instrument’s lead mechanical engineer.
Read the full story on the space telescope that could transform the search for distant planets.
—Eshan Raul
The machine that could change the world will be housed in a room that looks like a data center crossed with an ice cream factory.
Inside, some 100 stainless-steel cabinets each hold hundreds of chips. On those chips, thousands of light particles will fly through a maze of optical switches and beam splitters. Each photon must be accounted for, because precisely measuring where it ends up will help answer questions that current computers might take millions of years to solve.
This computer, as described, does not exist. It’s the brainchild of a company called PsiQuantum, founded in 2016 by four physicists from UK universities. In a crowded field of deep-pocketed competitors with similarly fantastical visions, the company aims to be the first to build a useful quantum machine.
—James O’Donnell
This is our latest story to be turned into an MIT Technology Review Narrated podcast, which we publish each week on Spotifyand Apple Podcasts. Just navigate to MIT Technology Review Narrated on either platform, and follow us to get all our new content as it’s released.
The must-reads
I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.
1 OpenAI says one of its models carried out an autonomous hack
It escaped its testing sandbox and breached AI research platform Hugging Face. (Reuters $)
+ OpenAI described it as a cybersecurity test that went badly wrong. (WSJ $)
+ The hack is among the first known cyberattacks by an AI acting on its own. (FT $)
+ Even simple AI attacks are cause for alarm, though. (MIT Technology Review)
2 France has become the first EU country to ban social media for under-15s
Its parliament approved the ban, which President Macron championed. (NYT $)
+ He pledged to enforce it by September, the start of the school year. (Guardian)
+ But critics say it’s unconstitutional and impossible to enforce. (NPR)
3 The US and China will hold talks over AI in September
Treasury Secretary Scott Bessent will lead the US side. (Reuters $)
+ Chinese models have Trump’s AI world at war with itself. (MIT Technology Review)
4 Publishers are considering cutting Google off as AI reshapes search
News outlets are weighing lost traffic against AI exposure. (WSJ $)
5 Samsung is in talks to invest €1 billion in Mistral
The French AI firm is positioning itself as an alternative to US models. (FT $)
+ It’s Europe’s leading AI firm, but US peers dwarf its $20 billion valuation. (Reuters $)
6 Amazon pushed up rivals’ prices, leaked records allege
Internal emails reveal tactics that allegedly reshaped online pricing. (Guardian)
7 Trump has tapped a Big Tech critic to lead the DOJ’s antitrust division
Adam Candeub has called for tougher federal competition enforcement. (FT $)
8 New drilling methods could unlock geothermal energy almost anywhere
They aim to unlock Earth’s enormous heat reserves. (New Scientist $)
+ AI is uncovering hidden geothermal energy resources. (MIT Technology Review)
9 AI researchers have proposed a “Genie coefficient” for measuring AI risks
It would track the gap between intent and action. (IEEE Spectrum)
+ We need better ways to evaluate AI. (MIT Technology Review)
10 Japan’s AI boom has two unlikely winners: a toilet maker and an MSG giant
They’re supplying critical chipmaking materials. (CNBC)
Quote of the day
—Paul Dergarabedian, a movie industry analyst at Comscore, tells Fortune that Christopher Nolan’s commitment to human filmmaking provides an attractive counterweight to Hollywood’s embrace of AI.
One More Thing
Taiwan produces the majority of the world’s semiconductors and more than 90% of the most advanced chips needed for AI applications. Many believe that’s helped deter China from invading the island. But now some Taiwan specialists and citizens are worried that this “silicon shield” is cracking.
Facing pressure from Washington, TSMC—the world’s largest chipmaker—is expanding manufacturing abroad. In Taiwan, there are worries that this will dilute the company’s power at home, making the US and other countries less inclined to defend the island.
Find out why Taiwan’s chipmaking dominance could be key to its future security.
—Johanna M. Costigan
We can still have nice things
A place for comfort, fun, and distraction to brighten up your day. (Got any ideas? Drop me a line.)
+ Thrifty filmmakers have masterfully recreated Star Wars on a $10 budget.
+ A man discovered squirrels hug and kiss their loved ones in the privacy of their homes.
+ Toronto’s floating waterfront store is reimagining one of the most familiar spaces across cultures.
+ These animations of Sesame Street characters performing classic tracks like Underworld’s “Born Slippy” will brighten up your day.
Nabla, the Paris-based maker of ambient scribes used to automate clinical documentation, says it’s playing the long game. On Tuesday the company announced a new leader and reiterated its commitment to fundamentally new AI technology it believes can help it beat the competition.
The company, which last raised a $70 million Series B last summer, announced a new CEO, Brian Manning, who has served as chief revenue officer at care coordination software company PatientPing and its acquirer, Bamboo Health, before taking over as Bamboo’s president. The shift “marks the next phase of Nabla’s go-to-market strategy,” the company wrote in a press release.
“We really haven’t built our brand in the United States. We really haven’t accelerated our go-to-market in line with what others are doing. And as we look towards 2027, that’s something we’re absolutely going to be doing,” Manning said in an interview with STAT. Chief operating officer Delphine Groll said that 100% of the company’s revenue is from the U.S.
MilliporeSigma opened a new €25 million BioReliance® testing facility at the company’s global headquarters in Darmstadt, Germany. The facility expands access to commercial drug substance and drug product release testing as well as stability testing for biopharmaceutical companies developing and commercializing therapies in Europe, according to the company.
“As demand for biologics and novel therapies continues to grow, our customers need reliable, compliant testing capabilities closer to where their products are developed and commercialized,” said Paolo Carli, head of advanced solutions for the life science business of Merck KGaA. “Our new testing facility combines best-in-class analytical characterization services with more than 75 years of BioReliance expertise to help our European customers move critical therapies toward patients with greater speed and confidence.”
The 2,000-square-meter facility is designed to help customers meet European requirements for in-region drug substance and drug product release testing and to expand the company’s ability to support customers from drug development through commercialization. The site will also offer GMP-compliant stability studies for monoclonal antibodies and cell therapies, addressing the growing demand for biologics testing across Europe.
Located close to major clinical trial sites in Germany, France, Spain, the Netherlands, Belgium and Italy, the Darmstadt facility is strategically positioned to support biopharmaceutical companies seeking to release drug products into European markets, pointed out Carli. By adding these capabilities in the heart of Europe, the company is strengthening its support for customers managing increasingly complex development, quality and regulatory requirements, he added.
A MilliporeSigma spokesperson noted that the BioReliance sites form a global testing network that allows customers to scale across geographies and work with the company across continents. Among the company’s leading technologies is the Blazar® platform, which moves the biosafety testing paradigm from traditional methods to rapid molecular approaches to significantly reducing testing timelines for virus detection.
The Aptegra® CHO genetic stability testing streamlines a previously complex and time-intensive process into a single assay, continued the spokesperson.
MilliporeSigma lists the opening of the Darmstadt facility as one of several significant investments the company has made to grow its global contract testing footprint. In 2024, the company opened a €290 million biosafety testing facility in Rockville, MD, and expanded biosafety testing capacity by 40% across its Glasgow and Stirling sites through a €22 million investment. The company also cites the new BioReliance facility as reflecting the firm’s continued commitment to its global headquarters in Darmstadt, where €2.5 billion has been invested since 2015.
The post New €25 Million BioReliance Testing Facility Opens at Merck KGaA Global Headquarters in Germany appeared first on GEN – Genetic Engineering and Biotechnology News.
Every morning, airline dispatchers, grid operators, and farmers around the world make decisions based on the same thing: a weather forecast.
While these forecasts are something that most people glance at for two seconds, weather predictions influence major strategic decisions in many industries, with real money, livelihoods, and even actual lives at stake. Farmers use them to determine which crop variety to sow, when to fertilize, how much to invest in irrigation infrastructure, and how long livestock should graze. Utilities use them to decide where to build solar and wind farms, as well as how to price wholesale electricity. Predictions are used to warn people about extreme weather and to trigger emergency response measures. More recently, weather predictions have become relevant for an emerging industry: prediction markets, where people bet money on all kinds of real-world events, including the weather.
However, the temptation to manipulate weather data to get an edge in these markets, combined with a collective move toward data-driven AI weather forecasting, is starting to put the accuracy of weather predictions at risk. These risks are relatively manageable for now, but as experts in the field, we can foresee scenarios where they snowball into far bigger, more systemic problems.
To develop weather predictions, we need accurate observations of current conditions. These are collected from several sources, including weather stations at airports, utilities, or transport services. Traditional operational systems like the Weather Research and Forecasting model or the European Centre for Medium-Range Weather Forecast (ECMWF) Integrated Forecasting System combine these observations with numerical approximations in order to estimate future weather patterns.
Sometimes, weather stations have issues because of, for example, instrument failures or upgrades in equipment. These can be caught either in real time (through checking and correction) or retroactively. Traditional forecasting systems also have a built-in safeguard called data assimilation: Every incoming measurement is weighed against what the physical model says should be happening and against readings from nearby stations.
Together, these mechanisms help keep weather observations reliable and predictions robust. However, new threats are putting observational accuracy at risk. Earlier this year, news outlets reported that the weather station at Paris Charles de Gaulle Airport (CDG) had been manipulated to record suspicious temperature spikes on April 6 and April 15, 2026. Authorities speculate that a hand-held hairdryer or lighter might have come into play. Either way, it led to some big payouts for online prediction-market gamblers who had bet it would hit 22 °C (71.6 °F) on days when the actual average was around 18°C (64.4°F). One individual won $20,000.
Fortunately, tampering with a single station like this can usually be caught by human monitoring or current statistical methods. In this case, members of a French climate nonprofit association noticed the anomalies by chance and raised the alarm.
But what if there are no human monitoring systems in place? And what about other types of manipulation? What if, instead of tampering with one station, someone remotely nudged the readings at many stations at once—making each change small enough to look plausible on its own? Existing quality controls struggle to catch this kind of coordinated manipulation. And time works against us; careful checks of data and metadata take hours or days, but forecasts have to go out on schedule, whatever the weather is doing.
The shift toward artificial intelligence in weather prediction raises the stakes. These methods are even more dependent on accurate, reliable weather observations; in fact, they are known as “data-driven models.” For example, researchers at ECMWF are exploring whether high-quality weather forecasts can be produced directly from raw observations, skipping the assimilation step that currently acts as a quality filter. Other researchers are going one step further; combining geospatial data (including weather station data) with large language models and agentic AI to support real-time, autonomous decision-making during extreme events such as storms.
Possible benefits are improvements in accuracy, efficiency, and speed. But removing humans from the equation introduces a vast range of new risks.
At the low end of the risk scale, an individual speculator manipulates a weather station for personal gain—that is the CDG Airport case. One step up: A group of traders could coordinate to bias forecasts of renewable energy output, moving wholesale electricity prices and leaving whoever is on the other side of the trade holding the loss. And at the far end, a state actor or saboteur could manipulate one or many stations to set off an early warning system or even keep one silent when it should sound. Step by step, the risk grows, from fraud to compromised disaster preparedness to a matter of national security.
As long as there are financial (or other) incentives to manipulate observational data, adversaries will search for new opportunities, and it is our task to stay one step ahead. Here are three ways.
1. Watch the stations. Data quality controls should include station security, anomaly detection and correction, and human oversight. Weather stations should be monitored continuously to deter tampering. Data homogenization methods that clean up weather records also need to get faster, with the goal of catching problems in real time. This will become increasingly important as agentic AI systems use these data to deliver real-time decisions. Finally, human oversight is needed to flag questionable data and model outcomes. After all, it was humans who caught the CDG Airport manipulation.
2. Protect the data to safeguard the AI. Data defense mechanisms must be positioned throughout the AI pipeline. AI explainability and adversarial robustness tools can help us understand the underlying data and the AI model outputs, help us identify data- or model-related issues, and potentially make us more resilient to adversarial attacks.
3. Ensure continuous accountability along the chain. Observational data passes through many hands: the operators who run the stations, the national weather services that steward the records, and the forecasting centers that turn them into predictions. No single one of them can protect data integrity alone—each guards its own link, and any anomaly needs to be communicated along the whole chain, from station operators to the people acting on the forecast.
It is fortunate that the situation at CDG Airport was caught, but it should serve as a wake-up call. As the role of observational data grows in weather forecasting, we need to adapt to evolving threats. This means protecting our data and models by strengthening existing oversight and accountability structures, and improving coordination among key partners.
This op-ed was written by:
Tours, France-based Vermon has opened a new TransducerWorks manufacturing facility and acquired OEM ultrasound subsystem specialist Modeleus to launch the new Vermon Group platform. The new 30,000-square-foot, purpose-built TransducerWorks facility in Pennsylvania is four times the size of the previous site. It features ISO 7 and ISO 8 certified cleanrooms, an integrated machine shop and…
The post Ultrasound CDMO Vermon opens new plant and buys subsystem specialist appeared first on Medical Design and Outsourcing.
Using publicly available 2024 VISUCHIR (Visualisation de la Chirurgie) benchmarking indicators, we performed a descriptive ecological comparison of national private-sector values and 4 early-adopter French private departments implementing the Betty Coaching perioperative digital pathway; early-adopter departments showed a directionally favorable, unadjusted profile for same-day discharge, mean length of stay, and VISUCHIR-reported readmission-evolution indicators, without causal inference.
<img src="https://jmir-production.s3.us-east-2.amazonaws.com/thumbs/15445ada73db488de7475c790390a086" />
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology.
—James O’Donnell
When Anthropic announced last week that it had found a new window into its models’ “internal thoughts” as they reason through answers, there was one colleague I had to talk to: senior editor Will Douglas Heaven.
Aside from having a PhD in computer science, Will has spent a lot of time digging into what we can say about how AI models work. I spoke with him about what we should take from Anthropic’s new (and typically quirky) research. Here’s what he had to say.
This article is from The Algorithm, our weekly AI newsletter. Sign up to receive it in your inbox every Monday.
Today’s AI systems can generate text, images, and code with impressive skill, but they still struggle with the complexities of the physical world. To bridge this gap, many researchers believe you need something called a world model.
At a LinkedIn Live event today, MIT Technology Review will investigate how this technology could transform robotics and help unlock a new generation of intelligent machines. Join Will Douglas Heaven, our senior editor for AI, and Sam Sinha, founding AI researcher and head of world models at 1X Technologies, for the discussion.
Register here to attend the free session at 9:30 PDT, 12:30 PM EDT, and 5:30 PM BST.
The must-reads
I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.
1 New York has become the first state to enact a data center moratorium
Its governor banned large data-center construction for up to a year. (WSJ $)
+ A bill passed by state lawmakers could go even further. (Verge)
+ Everyone hates data centers. (MIT Technology Review)
2 Smartphone shipments have hit a 13-year low due to the memory crunch
They fell 11% in the second quarter of 2026. (Reuters $)
+ The memory chip shortage has increased prices. (Gizmodo)
+ And threatens the promise of Moore’s Law. (MIT Technology Review)
3 Sugar molecules have been found in interstellar space for the first time
It hints that life on Earth may have been seeded from space. (Nature)
+ And boosts the odds of living organisms existing elsewhere. (New Scientist $)
+ Researchers used radio telescopes and data to spot the molecules. (NYT $)
4 Nvidia has halved its Asia buyer list to stop AI chips reaching China
It introduced a “white list” of companies that passed tougher checks. (FT $)
+ It moved amid tighter chip controls from the Trump administration. (Reuters $)
5 Russian state hackers are targeting routers to spy and steal, the US warns
The government has warned users to secure their devices. (Ars Technica)
+ Now is a good time for doing crime. (MIT Technology Review)
6 Trump moved his crypto gains into stocks while urging people to buy more
His crypto projects earned him a fortune—but steep losses for retail buyers. (Reuters $)
+ He’s called for Congress to pass a new crypto bill to honor Lindsey Graham. (CNBC)
7 A new cell therapy has saved four children with terminal brain cancer
They were treated with an experimental immunotherapy. (New Scientist $)
+ Access for older children will also be limited. (Bloomberg $)
8 The LAPD has halted use of Flock surveillance cameras due to privacy issues
Flock’s automated license plate readers have caused concerns. (LA Times $)
+ It’s also been criticized for sharing data with state and federal officials. (Engadget)
9 The US has approved launching a space mirror that reflects sunlight onto Earth
As part of a controversial plan to power solar panels round the clock. (Wired $)
+ But geoengineering faces many practical challenges. (MIT Technology Review)
10 Anthropic says Claude’s values vary depending on your language
It’s most cautious in English and most deferential in Arabic. (Gizmodo)
Quote of the day
—SoftBank CEO Masayoshi Son predicts that AI will overtake human intelligence by 2040 in a speech at his company’s annual corporate conference in Tokyo, Reuters reports.
One More Thing

Millions of embryos created through IVF sit frozen in time, stored in cryopreservation tanks around the world. Many are left in a peculiar limbo, with no clear path forward.
UK residents can discard them, make them available to other prospective parents, or donate them for research. People in the US can also opt for “adoption,” “placing” their embryos with families they get to choose. In Germany, people aren’t typically allowed to freeze embryos at all. And in Italy, unused embryos must remain frozen, ostensibly forever.
While these embryos remain in suspended animation, patients, clinicians, embryologists, and legislators must grapple with the essential question of what to do with them. What do these embryos mean to us? Who should be responsible for them?
Dive into the ethical and legal challenges surrounding frozen IVF embryos.
—Jessica Hamzelou
We can still have nice things
A place for comfort, fun, and distraction to brighten up your day. (Got any ideas? Drop me a line.)
+ This website turns live LA Metro data into music.
+ British grammar is enlivening the American World Cup.
+ Comedy icon Mel Brooks recently turned 100. Here’s a look back at his legendary career.
+ Take a trip through modern music with this cinematic set from Thomas Bangalter, one-half of French house music duo Daft Punk.