STAT+: For a Georgia entrepreneur, health coverage has never been affordable

Amy Bielawski has gone most of her life without health insurance. 

For 32 years, the 61-year-old has run her own entertainment company in Tucker, Ga. — setting up bounce houses, petting zoos, stilt walkers, and other attractions for family and corporate events. For several years, she did two of her specialties, face painting and balloon sculpting, for kids before Atlanta Hawks home games. 

One morning this past spring, Bielawski delivered a singing telegram to a woman getting off the graveyard shift at a Waffle House. Dressed as a chicken in a bikini, she sang a medley of songs that included The Beatles and Stevie Wonder, before ending with a birthday twerk.

Continue to STAT+ to read the full story…

Building tech in the world’s secret R&D hub

Apple. Anthropic. Disney Research. Google. Meta. Microsoft. NVIDIA. OpenAI. Few places outside Silicon Valley can claim R&D hubs from all of these companies. Fewer still are concentrated in a city of just over 400,000 people—roughly half the size of San Francisco.

Over the past two decades, however, many of the world’s most influential technology companies have established R&D operations in and around Zurich, Switzerland. What began with Google’s decision to build its largest R&D hub outside the United States has evolved into one of the world’s most concentrated centers for AI research, talent, and commercialization, in certain areas at a higher density than Silicon Valley. 

The question is why so many technology leaders keep choosing the same place to build and scale.

Located at the center of Europe, Greater Zurich Area, a region spanning the cantons of Glarus, Graubünden, Schaffhausen, Schwyz, Solothurn, Tessin, Uri, Zug, and Zürich, the region of Winterthur, and the city of Zurich, combines access to major markets with political stability, regulatory predictability, and strong intellectual property protection. And Zurich Airport connects the region directly with key business hubs across Europe, North America, and Asia, making it an efficient base for international operations.

The country’s innovation performance reinforces this position. Switzerland has ranked first in the Global Innovation Index for more than a decade, leads the world in patents per capita, and invests over 3.3% of GDP in research and development. Earlier this year, google.org pledged a $1 million grant to the Swiss National AI Institute, a joint effort to advance AI research for the public good.

Switzerland’s venture ecosystem reflects a similar focus. Over 60% of Swiss venture capital is invested in deep tech—the highest share globally by a large margin and nearly twice the share of major economies like Germany, France, and the UK. And, according to the Swiss Deep Tech Report 2026, at $1,470 invested per capita, Switzerland commits more to deep tech per capita than any other country in Europe.

The economics of specialization

While Switzerland is one of Europe’s most expensive locations for talent and operations, salaries remain at a fraction of those in Silicon Valley. The talent pool is small by global standards. Scaling a team quickly is harder in Zurich than in London, Paris, or Amsterdam. For early-stage companies that need to hire fast and burn lean, that trade-off is real. For companies building specialized AI capabilities, however, the equation works: The objective is to assemble the right team, not the largest one.

Switzerland’s economy is built around high-value, knowledge-intensive work. Productivity is among the highest in the world, and companies concentrate on functions that depend on specialized expertise rather than large workforces. For companies developing advanced AI capabilities, cost is often weighed against factors that are harder to replicate elsewhere: direct access to leading universities and research institutions, regulatory stability, and a quality of life that helps attract and retain skilled international talent.

A high-density AI ecosystem

Within Switzerland, the Greater Zurich Area concentrates many of the ingredients required to build and deploy AI systems.

The defining characteristic of this region is density. Many of the world’s leading AI companies, research institutions, investors, and startups operate in close proximity, creating connections between talent, capital, and ideas.

For example, Google engineers teach at ETH Zurich. ETH graduates join companies such as Anthropic. Researchers launch startups, while former employees of global technology firms go on to found new ventures of their own. Investors, founders, academics, and corporate teams encounter each other repeatedly through shared networks, industry events, and professional circles. In a region of this size, collaboration often happens less through formal introductions than through proximity. While talent flows freely, it rarely leaves the ecosystem.

One indicator of the region’s maturity is its ability to convene. Events such as the Zurich AI Festival will bring together more than 6,500 guests this September 28 to October 3. With more than 35 confirmed events across AI and the arts, AI literacy, health, technology, and policy, it is designed as a platform for cross-sector exchange. Its flagship events, the AI + X Summit, AI + Environment, and the AI + Policy Summit, will bring together internationally recognized leaders alongside researchers, policymakers, venture capitalists, and entrepreneurs, convening international voices and fostering dialogue across sectors.

Research, talent, and company creation

At the center of the country’s AI capabilities are institutions such as ETH Zurich, the University of Zurich, École Polytechnique Fédérale de Lausanne (EPFL), Scuola Universitaria Professionale della Svizzera Italiana (SUPSI), and Zürcher Hochschule für Angewandte Wissenschaften (ZHAW).

ETH Zurich ranks among Europe’s leading universities for deep tech commercialization, generating more than 40 spin-offs and startups in 2025 alone, helping create some of the continent’s most valuable technology companies.

The Stanford AI Index 2026 reinforces that picture: Switzerland ranks first globally for AI researchers and inventors per capita, with 110.5 per 100,000 inhabitants—ahead of Singapore (109.5), Sweden (80.6), and the United States (64.8). And the IMD World Talent Ranking ranked Switzerland as number 1 for the 10th consecutive year, leading globally in investment, development, and talent appeal.

Engineers, researchers, and founders move frequently between universities, startups, and established technology firms, creating strong knowledge flows across organizations. That density is increasingly attracting companies from outside the region too. Even before formally announcing their Zurich office, Exa.ai received a strong pipeline of candidate applications. ‘To assemble the greatest search team in the world, you’ve got to meet people where they are,’ says Will Bryk, the company’s CEO and co-founder. ‘And many are in Greater Zurich.’

Former Google Switzerland employees alone have founded approximately 210 companies and created around 2,600 jobs over the past two decades. For a country of around nine million inhabitants, the multiplier effect is significant. Large technology firms contribute not only through direct employment, but also through the creation of new companies and the transfer of expertise.

Why the Greater Zurich Area complements Silicon Valley

For many technology companies, Switzerland is not a substitute for Silicon Valley. The two serve different functions within the AI value chain.

Silicon Valley remains unmatched in scale, venture capital, and frontier model development, but for global technology companies, an R&D presence in Switzerland has increasingly become a strategic complement: a way to access specialized talent, stay close to leading research, and build capabilities that will shape the next generation of products and services.

This is particularly relevant for companies working at the intersection of AI and the physical world. Switzerland offers direct access to leading universities, industrial partners, and sectors such as healthcare, finance, manufacturing, and robotics, where reliability, compliance, and precision are often as important as raw model performance.

Geography is strategy

Global AI leaders came to the Greater Zurich Area because the region concentrates capabilities that are often distributed across multiple locations: world-class research, specialized talent, industrial partners, capital, and pathways to deployment. Those advantages were built over decades, not years.

For companies evaluating where to build the next generation of AI products, the answer may not be another larger ecosystem. It may be one where the distance between research, talent, capital, and deployment is measured in minutes rather than hours.

Learn more about the Greater Zurich Area.

This content was produced by the Greater Zurich Area. It was not written by MIT Technology Review’s editorial staff.

Agent confidence on the technical frontier

Enterprise investment in AI is booming. Gartner is calling 2026 an “inflection year” for organizations to align their AI projects with strategic business objectives. As the pressure to prove ROI mounts, executives and technology leaders are looking to agentic AI to drive the measurable financial outcomes their businesses seek.

A prime opportunity for AI agents exists in the tech function, where IT infrastructure costs are projected to grow two to three times by 2030, even as budgets remain unchanged, according to McKinsey. And in the last 18 months, tech teams—the engineers, developers, architects, and other practitioners who are building, deploying, and continually improving their organizations’ infrastructure and applications—are clearly putting agents to work.

The ultimate promise of agents is not only to automate tasks but to manage and coordinate entire workflows, pursuing business goals in a way that allows humans and agents to work together. Given the risks involved in automated decision-making, teams cannot delegate the work that agents do without confidence that they are fully capable of performing the task and that it will do so in a safe, reliable, and secure manner.

Among technology experts, our research shows that teams are exceedingly confident about using agentic AI across a significant amount of AI, data, and cloud tasks.

Where agent readiness drops is largely due to a lack of business context being supplied to agentic systems. The more complex the task, the more reasoning capability an agent requires and the greater its need for business context. Such context-generation capabilities for agents are still at an early stage of development, especially in situations where enterprise data is difficult to wrangle and connect into the agent lifecycle at the speed and quality in which developers and executives need it. Human oversight is a key factor of success in deploying agentic AI.

Knowing that tech teams are in a pivotal position to lead this transformation, the experts we interviewed expect agent confidence to accelerate as experience with agents deepens and business environments mature. “As we design agents to operate within the same operational boundaries, identity systems, and governance models that teams already use, they start to behave more like the systems organizations already trust,” says Jeremy Winter, corporate vice president and chief product officer at Microsoft Azure Platform.

This report, based on a survey of 300 global technology experts, ranks 101 tasks across AI, data, and cloud workflows based on respondents’ confidence in agents acting on their behalf. It also examines how technology teams view the opportunities and challenges related to agentic AI, along with the potential for the technology to enhance their careers.

Key findings from the report include:

Confidence in agents is surging for measurable tasks and growing in areas of complex judgment. Technology experts overwhelmingly believe agents help with everyday work including streamlining processes, improving performance, and reducing repetitive tasks. Confidence is highest for processes like generating reports and boilerplate code, and there is clear opportunity where tasks involve multistep workflows and advanced reasoning to make decisions.

Data workflows are the breakthrough domain. Tech teams trust agents most where structure can provide a reliable foundation for decisions. This includes areas such as data quality monitoring, visualization anomaly detection, real-time data stream monitoring, and data profiling. This is where domain experts closest to the point of data generation can provide context to allow agents to act and deliver trusted outcomes.

Download the full report.

Read the Microsoft Cloud blog by Amanda Silver, corporate vice president of Microsoft 365 Core and Work IQ, which underscores the importance of keeping humans in the loop and how systems thinking advances careers. And for a deeper dive into data workflows as a breakthrough use case for agents, check out the Fabric blog to hear from Kim Manis, corporate vice president of Product for Microsoft Fabric.

This content was produced by Insights, the custom content arm of MIT Technology Review. It was not written by MIT Technology Review’s editorial staff. It was researched, designed, and written by human writers, editors, analysts, and illustrators. This includes the writing of surveys and collection of data for surveys. AI tools that may have been used were limited to secondary production processes that passed thorough human review.

The inevitable weakness of metrics

There are plenty of useful things a metric can reveal. There are even more it can obscure or corrupt. It took me well over a decade of tracking my own life in ever greater detail to fully appreciate this duality, which probably reveals something about both me and the nature of measurement.

Like a lot of people bitten by the self-quantifying bug, I initially started gathering personal data to pursue a nebulous collection of goals and desires. As a sedentary technology journalist, I wanted to feel better physically and emotionally, to get outside more, and—where possible—to bring order to some of the messiness and uncertainty of my daily existence. These all seemed to be things that could be improved with the cool clarity of numbers.

Self-quantifiers often get stereotyped as obsessive self-optimizers (and many of them are), but my reasons for producing and collecting personal data were less about life-maxxing and more about life meaning—at least at first. As most people who know me will attest, I do not have now, nor have I ever possessed, a “productivity mindset.” I’m also not all that interested in life hacks, shortcuts, or new ways to compare myself with other people. Instead, what I wanted out of metrics—what I hoped I could divine from a never-ending stream of numbers about my health, work, and social life—was something more elusive: self-knowledge. This was my first mistake. 

The idea that the more we know, the better is so profoundly embedded in our culture that it feels weird to even point it out. Since at least as far back as the Enlightenment, the primary way we’ve all agreed to go about knowing more has been through measurement and quantification. After all, more knowledge—more data—leads to better decisions, which leads to happier, more fulfilled people. Or so we’re told, and with increasing frequency in the era of AI. 

When two Wired magazine editors, Gary Wolf and Kevin Kelly, coined the term “quantified self” in 2007 and helped launch the movement we are all now helplessly a part of, they were essentially selling this very idea. “Unless something can be measured, it cannot be improved,” wrote Kelly in an early blog post, doing his best impression of Lord Kelvin. “So we are on a quest to collect as many personal tools that will assist us in quantifiable measurement of ourselves.” Almost 20 years later, that quest is easier than ever thanks to a flood of devices, apps, and websites all designed to help us build our self-­knowledge through numbers. 

My first tool was a small, plastic clip-on Fitbit I started using in 2011. It did one thing: count the number of steps I took in a day. As a lifelong video game player, I was already well acquainted with the motivational power of simple scoring systems, and I hoped my new gadget would offer the gentle numerical nudge I thought I needed to step away from my Twitter feed and, if not touch grass, at least walk next to some. Walking also seemed to be one of the few times I had what could charitably be called intelligent ideas, which seemed like another promising by-product of doing more of it.

Alas, that was short-lived. I can’t tell you precisely when “getting out into nature more” or “thinking smarter thoughts” stopped mattering to me as goals, but I suspect it took no more than a few weeks. What I can say with certainty is that my initial goal of 6,000 daily steps quickly turned into 10,000, which then jumped to 15,000 and eventually settled at 20,000 for years. Stories about becoming a “steps guy” are clichéd at this point, and they’ve earned that status for a reason.  

It didn’t take long for me to trade in pedometers for heart-rate monitors (I also started running), smartwatches, sleep-tracking rings, and an embarrassing number of macronutrient-­tabulating apps. Outside the health and fitness realm, my early career as a journalist also happened to coincide with the rise of social media and web analytics tools like Chartbeat, which promised to further quantify ­difficult-to-measure aspects of my life, like “job success” and “impact,” by tracking things like page views, followers, retweets, likes, and all sorts of other attentional metrics that now carry great weight.

Metrics inevitably redefine your core sense of what’s important, whether you’re aware of the trap or not.

Ultimately, during the 10-plus years I diligently tracked my heart rate, steps, active calories, sleep, story engagement time, stress levels, and other metrics, I gained virtually nothing in terms of greater self-knowledge. (I suppose I did learn that I liked to make numbers go up and down, but who doesn’t?) The swirl of data that followed me everywhere did not lend additional meaning or insight to the way I relate to myself, my work, or the important people in my life. In fact, the more I used numerical proxies, the worse I felt about pretty much everything. 

What I did learn were two important lessons about what happens when you try to quantify the minutiae of your life. First and foremost, whatever the amount of data you’re currently collecting about yourself, it will never feel sufficient. There’s always a new metric around the corner, a better way for a tracker to remix its readings and more accurately measure what’s “important”: heart rate variability, daily stress, exercise “readiness,” cardiovascular or “fitness” ages. Measurement begets more measurement. You can count on it. 

book cover
The Score: How to Stop Playing Somebody Else’s Game
C. Thi Nguyen
PENGUIN PRESS, 2026

The second lesson was less obvious but no less significant. The more personal or nuanced your goals are when you set off on your self-quantifying journey, the more likely it is you will ultimately replace them with some simplified metric or ranking. Want to become a better journalist? Why not use page views and leaderboards as a proxy for success? Enjoy cooking and want to improve? Foodie metrics dictate that more complicated recipes with longer ingredient lists are the answer. Even when we know that the value of good journalism isn’t reflected in how many people read a given story or that the joys of cooking are as much about improvisation and experimentation as about successfully following some complex recipe, it’s hard to resist the allure of a simple score or stat. Metrics inevitably redefine your core sense of what’s important, whether you’re aware of the trap or not. 

Over the years, people have invented various terms to describe this phenomenon. In his recent book The Score: How to Stop Playing Somebody Else’s Game, the philosopher C. Thi Nguyen calls it “value capture.” Value capture happens, he says, when you adopt external sources of measurement and then let them rule you without adapting them to suit your life. “In value capture, you’re essentially outsourcing your values,” Nguyen writes. “You’re letting an external metric or ranking set what’s important for you.” Crucially, you’re also outsourcing the process of figuring out your own sense of meaning. It’s why my walks quickly shifted from feeling meditative to prioritizing miles. 

Individuals, institutions, and indeed entire societies can fall prey to value capture. In fact, once you start noticing it, you start seeing it everywhere—in journalism, education, and business, but also in our food, our hobbies, and, yes, the way we measure our health and happiness. Here’s how Nguyen puts it:

Value capture happens when a restaurant stops caring about making good food and starts caring about maximizing its Yelp ratings. It happens when students stop caring about education and start caring about their GPA. It happens when scientists stop caring about finding truth and start caring about getting the biggest grants. It even happens in religion. A pastor recently told me that his church had become completely obsessed with baptism rates. The higher-ups had established an internal leaderboard in which the pastors competed on monthly baptism rates, and it was starting to dominate everybody’s attention. He’d found himself caring less about the long-term spiritual development of his flock and focusing more on trying to deliver popular sermons that would up his baptism rates and move him up that leaderboard.

At its core, The Score is trying to untangle a mystery that Nguyen, a specialist in the philosophy of games at the University of Utah, has been thinking about for a long time: Why is it that numbers and scoring systems in games can be the source of so much joy and fluidity and play, but public measures and institutional metrics (i.e., scores that apply to the real world) seem to drain the life out of everything and thrust us all into a bleak mindset of grinding optimization?

To begin to answer this question, he turns to one of the foundational inquiries into the limits of data and quantification, Theodore M. Porter’s 1995 book Trust in Numbers: The Pursuit of Objectivity in Science and Public Life. 

Porter, a historian of science who specializes in the social power of numbers, has spent his career looking at why quantification has become so dominant, not just in political and bureaucratic life but everywhere. One of his key insights about the inherent attractiveness of quantification, which he calls “a technology of distance,” is that it “minimizes the need for intimate knowledge and personal trust.” Put another way, metrics travel extremely well between different contexts and are easy to grasp and aggregate. 

Whether it’s a student’s GPA or a country’s GDP, these measures are understood by pretty much everyone. But that understanding comes at a price, Porter reminds us: To arrive at a clear metric, you inevitably need to simplify what you’re attempting to measure, often jettisoning heaps of nuanced, qualitative, or open-ended information so that others can find the resulting number legible. 

No one (hopefully) believes that a GPA captures in any meaningful way a student’s entire educational experience or aptitude for learning, but we’ve agreed to use it because more qualitative assessments are onerous to wade through and require expertise to decipher and compare. Ditto for the economic metric of GDP, which politicians and societies are now compelled to drive higher and higher because a group of economists once concluded that this figure correlates with general economic well-being.  

This is the essential tension at the heart of all data, argues Nguyen. Any institutional quantification, he says, requires that the evaluation procedure and its product be comprehensible across contexts. That profoundly limits what the metric can actually measure. “In value capture, you’re ultimately taking that decontextualized nugget and internalizing it,” he writes. “You’re guiding your life using an evaluative technology that has been engineered to travel between contexts, by stripping it of nuance.” 


Every so often I’ll find myself in friendly debate with a “numbers person”—a statistician, an economist, or a friend who’s still a committed self-quantifier. After patiently listening to my measurement-gone-awry examples—the disastrous attempt to quantify pain as “the fifth vital sign” in the mid-1990s (which exacerbated the opioid epidemic), or any of the countless examples of the McNamara fallacy, where decisions in academia, medicine, and politics are based solely on what’s easily measured—many will insist that I’m misunderstanding or misinterpreting the whole point of measuring. Metrics, they’ll say, are simply a means, and the important questions concern the ends for which they are used. In other words, these unfortunate outcomes amount to user error, not something inherently dangerous or misleading about the nature of measurement. 

At some point during these conversations, Goodhart’s Law will invariably come up, usually as an explanation the metrics-minded deploy for why the ends get all mucked up. The principle, which is attributed to the British economist Charles Goodhart, is often expressed as the following: “When a measure becomes a target, it ceases to be a good measure.” I have a profound dislike for Goodhart’s Law, not because I think it’s untrue, but rather for the way it gets interpreted.

As Nguyen notes, Goodhart’s Law says very little about why metrics fail to capture what’s important—or what to do about it. Find better measures, some will conclude. Don’t let metrics become targets, others will insist. These are not helpful takeaways. All measurements, I would argue, are in fact targets, whether you intend them to be or not. Metrics inevitably present one direction or option as better, Nguyen writes in The Score—“longer lifespans, faster student graduation rates, more page views, higher customer satisfaction scores.” What people are talking about when they bring up Goodhart’s Law isn’t human error; it’s actually a fundamental problem with measurement itself. 

I want to be clear here: Measurement can and does serve a number of vital functions. It has in a very literal sense made the modern world possible, with all its life­-saving, suffering-reducing, and awe-
inspiring scientific breakthroughs. When used with care and diligence, metrics can make our progress (or lack of it) clearer and more transparent. Are we decreasing carbon dioxide emissions or not? They can also introduce accountability into formerly opaque systems, such as by measuring whether a company is complying with state and federal regulations. They can even make us more objective, reduce biases, and galvanize us to act. 

But as Nguyen points out throughout The Score, the fundamental weakness of metrics comes when we use them to pursue subtler, more personal goals. What I think many of us miss—what I know I certainly missed—is that there are always trade-offs when you try to distill something important down to a data point. When we turn to metrics to understand ourselves, our social world, and culture as a whole, they will never come close to capturing what matters. Even worse, they’ll often actively obscure it. 


Today, I find that numbers have very little to offer when it comes to my daily work, my physical or mental fitness, my relationships, or any other part of my life I consider important. Granted, I’m lucky enough to be in relatively good health at the moment. I don’t have to track my glucose levels or monitor my blood pressure. As a freelance writer, I also have the luxury of not having numbers foisted on me in the form of key performance indicators (KPIs), objectives and key results (OKRs), or any of the endless quantitative evaluations that come baked into pretty much every corporate and gig economy job. 

Still, in a very real sense, there is no escaping metrics or, especially, the logic that accompanies them. Knowing has become numeric, and we all live in a world that increasingly sees us as a collection of numbers—as “data subjects.” The first and most urgent challenge, I’d suggest, is finding a way to keep us from seeing ourselves and each other that way. 

This won’t be easy. As Porter, Nguyen, and countless other philosophers, anthropologists, and historians have already observed, the language of numbers is largely how we ascribe value today—as well as how we digest and metabolize our relationships to ourselves, to others, and to the world around us. Indeed, many of us have accepted not only that metrics have a natural existence in human affairs but that there are in fact no aspects of human life that cannot be somehow translated into data.

Knowing has become numeric, and we all live in a world that increasingly sees us as a collection of numbers— as “data subjects.”

So how do we push back? Nguyen’s book offers a useful first step. As he notes again and again in The Score, believing that numbers say something real or useful about human needs and desires gives them power. We can, at the very least, start to seriously question that belief, to ask what meaning and pleasure we might be giving up in pursuit of a metric.

Doing so will hopefully lead to another realization: that playing the numbers game is ultimately a losing proposition for humans. If we insist on expressing our worth through attentional metrics and productivity scores, if we continue to turn intelligence and creativity into a series of benchmarks for AI to surpass, we’ve already lost. Of course machines will surpass us in a world built around metrics. That is literally what we create them to do. The answer is not to turn ourselves into machines too. 

If there’s one thing that keeps me up at night, it is that we’ve become so accustomed to seeing and understanding the larger world and ourselves through numbers that it has deprived us of the language to express what’s fundamental and valuable about our own humanity. We need this ability now more than ever, especially if we’re going to adequately answer two of the most important questions of our era: What are humans for? And what is AI for?

As part of my own attempts to disentangle myself from a life of numbers—efforts that started shortly before covid—I’ve abandoned most of the tools of measurement I spent a decade collecting. I’ve largely given up on social media. I stopped using apps to track my health and well-­being. The watch I currently wear tells me the time and the date and nothing else. 

In fact, the only holdover from my days of obsessive self-quantification is a dogmatic devotion to walking—without all the step counting, of course. These days, I walk when I’m feeling disillusioned or overwhelmed; I walk when I can’t figure out how to finish an essay; I also walk because I enjoy spending time outdoors with my dog and catching up on the details of my neighbors’ lives. The benefits of pursuing this daily activity are as clear and obvious to me as anything could be in life. I just can’t express them in a number. 

Bryan Gardiner is a writer based in Oakland, California.

Solvent Recovery Gains Ground in Bioprocessing

In addition to making products, a bioprocessor should be thinking more about solvents. “Solvent recovery is becoming a critical part of operational resilience and fiscal strategy for bioprocessing companies,” says Rudy Morin, engineering and modular solutions manager at Koch Modular. “It provides three primary benefits: operating expense reductions, supply-chain independence, and corporate sustainability.”

The financial case is especially compelling for bioprocessors that rely on high-purity HPLC- or USP-grade solvents, which are costly to procure and expensive to dispose of properly. By recovering and reusing solvents from waste streams, companies can meaningfully cut virgin-solvent purchases while reducing hazardous waste disposal costs. Morin notes that the economics tend to work in a bioprocessor’s favor. “The payback periods are often attractive given quantities and solvent costs, and the recovery system quickly becomes a predictable long-term asset,” he says.

Supply-chain reliability has become an equally pressing concern. Geopolitical tensions, severe weather, and transportation disruptions have laid bare the vulnerabilities in chemical sourcing. Solvent recovery addresses this by creating a closed-loop supply within the facility itself. “A solvent-recovery system gives bioprocessing facilities total control over their solvent supply and business continuity,” Morin says.

Implementation, however, is rarely straightforward. Bioprocessing waste streams typically contain multiple solvents, water, and solids. Such mixtures often demand sophisticated separation technologies, such as pressure-swing distillation, extractive distillation, vacuum distillation, or liquid-liquid extraction. “Each additional unit operation adds intricate controls and operational variables, making the initial design phase absolutely critical,” Morin says.

Capital costs present another barrier. Automated systems generally start in the low seven-figure range, with complexity driving costs higher. To manage risk, Morin recommends combining pilot testing, process simulation, and modular construction. Pilot testing clarifies feed characteristics and yields critical process data; simulation software optimizes designs before a dollar is spent on construction; and modular fabrication reduces project risk by moving work off-site, compressing schedules, and tightening quality control.

Looking ahead, Morin sees meaningful opportunities in advanced extraction technologies and modular deployment. Liquid-liquid extraction, for instance, can recover products directly from fermentation broths while enabling downstream solvent recycling. For facilities considering the leap, his advice is practical: start with a clear design basis, conduct a rigorous economic analysis, and engage experienced process-engineering partners early. “Any solvent-recovery stream is worth a conversation with an experienced process engineering company, given the multiple potential benefits,” he says.

As cost pressures and sustainability commitments converge, solvent recovery is increasingly positioned not as a compliance measure but as a strategic investment—one capable of delivering measurable value across operations, supply chains, and environmental performance.

The post Solvent Recovery Gains Ground in Bioprocessing appeared first on GEN – Genetic Engineering and Biotechnology News.

STAT+: Online care is caught in the crossfire as states crack down on corporate medicine

In less than a decade, telehealth has expanded from a sideshow of health care to an industry worth tens of billions of dollars. Companies like Hims & Hers and Teladoc have become household names, their ads interrupting streaming TV and flooding social media feeds with the promise of quick, convenient care.

Despite their popularity, few patients understand who’s actually taking care of them when they click through a telehealth site. 

National telehealth brands present a unified front to patients across the country. But in more than 30 states, it’s illegal for corporations to practice medicine. So behind the scenes, telehealth companies work with distinct, independent medical groups. Owned by physicians — who often hold 50 state licenses at once — those practices are meant to act as a firewall, making sure that clinical decisions are driven by patients’ needs, not the profits of the corporations they deal with. 

Continue to STAT+ to read the full story…

How the Pope’s Magnifica Humanitas offers a template for individuals to meet the AI moment

Pope Leo XIV’s new encyclical on artificial intelligence includes a statement that warrants serious attention from technologists and policymakers: “Technology is never neutral.” Magnifica Humanitas (“Magnificent Humanity”) is a clarion call to all people to act with courage and solidarity as we enter an age already being transformed by artificial intelligence, the greatest change in human life since the Industrial Revolution. As the pope says, the choice before us—the choice AI presents—is one between the Tower of Babel and the rebuilding of our common humanity. 

In the biblical story of the Tower of Babel, humans sought to build a massive structure that reached all the way to Heaven, only to have their project thwarted when God made those involved unable to understand one another. It was a pursuit fixated on relentless growth, divorced from any concern about God’s commandments or the human cost. It resulted in failure and atomization.

The Book of Nehemiah, however, offers a contrasting narrative, in which the rebuilding of Jerusalem after a period of violence and displacement becomes an opportunity for humanity to show its collaborative resilience. As the encyclical puts it, “The city is reborn, not through the initiative of one man, but through the shared responsibility of all: men, women, priests, artisans, heads of households and young people all play a part. It is an undertaking with God at the center, which rebuilds relationships before rebuilding with stones.” 

Is there any question which road we are currently barreling down? And can there be any doubt which we would do well to walk together? 

We are both Catholics, members of religious communities and longtime advocates within the movement for socially responsible investment. Of particular interest to us and that movement is Pope Leo’s point that AI is not some force of nature or hyperrational, ineffable entity. Instead, he reminds us, AI is ultimately another commercial product, one emerging at a point in history when excessive power over commerce and the wider society has amassed in a vanishingly small number of hands. 

It’s a powerful message. It’s also one that institutional investors have been acting on for years. This encyclical doesn’t break new ground so much as ratify a governance effort that’s already underway, led not by states or international bodies but by shareholders. When governments fail to meaningfully regulate, and corporations cannot be trusted to do what is beneficial beyond their own bottom line, people in society still have the power to set us on the right path, and indeed have the duty to do so. 

Around the world, AI systems are being deployed at scale with remarkably little institutional oversight. There is no AI safety board. The US Federal Trade Commission has jurisdiction over unfair practices but limited authority over algorithmic design. The National Institute of Standards and Technology publishes guidance that most companies ignore. The EU AI Act is partially in force but addresses only a sliver of the deployment surface.

Institutional investors have stepped into this vacuum. Coalitions including the membership of the Interfaith Center on Corporate Responsibility, representing investors managing over $400 billion in assets, have spent the past several proxy seasons filing resolutions demanding transparency, risk assessment, and accountability around AI deployment. Secular institutional investors have joined them, treating AI governance failures as material business risks.

Shareholders have called tech giants including Alphabet, Amazon, Nvidia, Palantir, and Uber to account and demanded that AI not be used for acts of violence or other violations of human rights. The importance of this aspect of corporate governance was highlighted tragically in the opening hours of the war against Iran, when AI was used to help identify targets for thousands of missile strikes that killed hundreds of people.  

Investors have also challenged executives at CVS and UnitedHealth Group to ensure that AI not be used to undermine the well-being of patients and quality of health care across the United States. 

At companies including Meta and Microsoft, shareholders have decried the environmental impact of AI data centers, which consume vast amounts of energy and precious water resources, and in turn can emit large amounts of greenhouse gases. 

Within creative industries, investors have challenged the leadership at companies like Disney, Netflix, and Warner Bros. to demand transparency about the ways they are using AI and to defend the inimitable human element in storytelling. 

Soon, with OpenAI, Anthropic, and Grok all set to enter the public markets, we will be able to exert similar influence over what are now all privately held entities.

These actions by concerned investors not only call out misdeeds but hold fast to an immutable truth: that it is wrong to use technology to kill, harm, or oppress people. Every human being has a right to safe and effective health care and the opportunity to earn a dignified living. The stories we tell each other matter and require the human creative spark. 

Investor advocates hail from a range of faith traditions. Some have no formal religious faith. Yet in their informed and tenacious advocacy, all these people echo the calls embedded within Pope Leo’s encyclical and act on its declaration that “it is essential that the use of AI, especially when it touches on public goods and fundamental rights, be guided by clear criteria and effective oversight.” 

Encyclicals mark time. A century from now, how will we be remembered for how we met this moment? Will we be seen as having been too timid or shortsighted to prevent a small group of unfathomably wealthy and self-interested people from seizing ever greater control over the human family’s shared destiny? 

Or will the years ahead be remembered as a turning point that helped us rebuild our common humanity? Let this be a time when people of good will and diverse talents come together through their own magnificent humanity to build a future that honors our Creator.

Father Séamus Finn, OMI, is a global leader in faith-based and socially responsible investing and a priest of the Oblates of Mary Immaculate, a missionary religious congregation.

Sister Susan Francois is the assistant congregation leader and congregation treasurer for the Sisters of St. Joseph of Peace.

Understanding the modern cybercrime landscape

Throughout 2025, HPE observed significant changes in how cybercriminals operate. Analyzing real-world threats, our HPE Threat Labs highlighted an industrialization of the cyber criminals’ methods in its new In the Wild Report, enabling greater scale, speed and structure in their campaigns. They typically use automation and AI to exploit longstanding vulnerabilities, and many have adopted a professional, corporate hierarchy to optimize their efficiency.

Cybersecurity threats today are as menacing as ever for enterprises, as any CISO or CIO can probably confirm. But, digging behind that straightforward statement, there is a much more nuanced, complex cybersecurity landscape at play. This can make it significantly harder to plan, execute, and sustain effective strategies and solutions to protect the network—plus the often valuable—sometimes priceless—data, apps, and assets it transports and stores.

But it can be done, with the right philosophy and strategy, and the right tools and insights.

We must first understand the contemporary cybersecurity landscape. This understanding can unlock the right strategy and then onward to identify the tools and insights necessary to protect an enterprise’s network effectively.

There are five primary factors influencing the landscape, some old, some new, all dynamic. These factors are distinct but often interdependent, both within themselves and with one or more of the others. Another meaningful way of looking at them is “internal” and “external”; as ever, understanding and dealing with what is in your control can also help to navigate and mitigate what is beyond your control.

Five key factors influencing today’s dynamic cybersecurity landscape

1. Expectations

The first factor is predicated on the fundamental reality of an enterprise’s reliance on its network. Most enterprises have already undergone some form of digital transformation and are reaping the day-to-day benefits. This means that the number of people, devices, and things using the network continues to grow; it also means that people’s expectations of the network are higher than ever before – they demand that it does exactly what they need it to do, typically across a proliferation of devices and from multiple locations. Conversely, many employees might not be fully aware of cyber threats and infiltration methods, so their skillsets can easily be the weak point that admits bad actors into the network.

Equally, senior management and board members have high expectations at a meta level. Embracing digital transformation and network reliance means the enterprise’s function and reputation are inextricably tied to that. Loss of reputation due to a security breach is a chilling prospect, as is the threat of financial penalty and revenue loss. So, in the minds of leadership, the network has to be safe from cyber threats and be compliant.

2. Financial pressures

The first factor arguably contradicts its neighbor in the landscape: general financial constraints and the pressure on CISOs and CIOs to achieve more with less. Despite the strategic reliance on the network and the expectation that it will be protected from cyber threats regardless, the appropriate latticework of defenses (e.g., skilled and right-sized IT teams using progressive tools and meaningful data insights, plus constant workforce education) is not always properly funded and sustained, particularly in the current tough economic climate.

3. Complex infrastructure operations

The ongoing pursuit of digital transformation and consequent network reliance also drives the third factor. Ironically, there is another facet of enterprise protection and financial control wrapped up in this. The widespread move from one-stop shops (avoiding IT vendor lock-in in favor of more competitive pricing and autonomy) has created a more complex, multivendor environment. This is coupled with multiple IT domains required to handle many diverse functions and layers of IT infrastructure (e.g., cloud, on-prem), all connected to the network. Complex, mission-critical IT operations now need to be monitored and protected from increasingly sophisticated cyber breaches.

4. Unpredictable geopolitics and economics

Shifting from the first three factors—all internal to an enterprise—the fourth is unquestionably external and without doubt the most intractable risk for any enterprise, individual, or industry group. Global uncertainty and tension are unavoidably putting even greater pressure on already-tight IT budgets, component supply chains and power costs. This can easily exacerbate existing constraints on cybersecurity budgets when vigilance and protection are more needed than ever. Unfortunately, in cyberspace one cannot always point a finger in one direction to identify an adversary. Geopolitical alliances in cyberspace are much more difficult to track, and defending against an escalating tension becomes an all-out fight to secure the network.

5. Evolving cyber threats

The fifth factor is obviously the epicenter of today’s cyber security landscape. According to the HPE Threat Labs’ report, governments were the most frequently targeted sector globally in 2025, followed by finance, technology, defense, and manufacturing. The prevailing global geopolitical and economic situation may further accelerate the twin motivations of nation state-linked espionage and organized crime for extortion and theft.

Use the network to protect the network… and beyond

The current cybersecurity landscape calls for a re-think of the network’s pivotal role and how it can manage an enterprise’s digital defenses effectively, dynamically, and comprehensively. Overall, the network can be an excellent security sensor and enforcement point, using built-in security capabilities rather than being a collection of devices with an inflexible, bolted-on security layer.

Much as cybercriminals use agentic and generative AI to intensify their campaigns, CISOs can stay ahead more easily by leveraging AI-driven network platforms for 24×7 automated management of security policy enforcement (e.g., zero trust), threat monitoring, and mitigation, encompassing devices, things, and users. Meaningful data insights can be harvested, analyzed, and recycled back into secure networking management tools for dynamic protection.

This approach helps the progressive enterprise to overcome increasingly sophisticated, multi-step, and prolific attacks, while better managing IT costs and simplifying oversight of IT operations. It can also significantly improve the user experience, going a long way to meet and even exceed those rising expectations consistently. 

As a strategy in today’s uncertain world, embracing this self-driving network paradigm enables flexibility, visibility, and consistency in an enterprise’s frontline digital defenses.

For more, read the “In the Wild” report.

This content was produced by HPE. It was not written by MIT Technology Review’s editorial staff.

Three things in AI to watch, according to a Nobel-winning economist

This story originally appeared in The Algorithm, our weekly newsletter on AI. To get stories like this in your inbox first, sign up here.

A few months before he was awarded the Nobel Prize in economics in 2024, Daron Acemoglu published a paper that earned him few fans in Silicon Valley. Contrary to what Big Tech CEOs had been promising—an overhaul of all white-collar work—Acemoglu estimated that AI would give only a small boost to US productivity and would not obviate the need for human work. It’s okay at automating certain tasks, he wrote, but some jobs will be perfectly fine.

Two years later, Acemoglu’s measured take has not caught on. Chatter about an AI jobs apocalypse pops up everywhere from Senator Bernie Sanders’s rallies to conversations I overhear in line at the grocery store. Some previously skeptical economists have gotten more open to the idea that something seismic could be coming with AI. A California gubernatorial candidate said last week that he wants to tax corporate AI use and pay victims of “AI-driven layoffs.” 

On the one hand, the data is still on Acemoglu’s side; studies repeatedly find that AI is not affecting employment rates or layoffs. But the technology has advanced quite a bit since his cautious predictions. I spoke with him to understand if any of the latest developments in AI have changed his thesis, and to find out what does worry him these days if not imminent AGI.

AI agents

One of the biggest technical leaps in AI since Acemoglu’s paper has been agentic AI, or tools that can go beyond chatbots and operate on their own to complete the goal you give them. Because they can work independently rather than just answering questions, companies are increasingly pitching agents as a one-to-many replacement for human workers.

“I think that’s just a losing proposition,” Acemoglu says. He thinks agents are better thought of as tools to augment particular pieces of someone’s work than something malleable enough to handle a person’s whole job.

One reason has to do with all the various tasks that go into a job, something Acemoglu has been researching in his work on AI since 2018. For example, an x-ray technician juggles 30 different tasks, from taking down patient histories to organizing archives of mammogram images. A worker can naturally switch between formats, databases, and working styles to do this, Acemoglu says, but how many individual tools or protocols would an AI require to do the same?

Whether or not agents will supercharge AI’s impact on jobs will come down to whether they can eventually handle the orchestration between tasks that humans do naturally. AI companies are in heated competition to prove that their AI agents can work independently for ever longer periods without making mistakes, sometimes exaggerating the results—but Acemoglu says many jobs will be spared from an AI takeover if agents can’t fluidly switch between tasks.

The new hiring spree

For years Big Tech has been offering staggering salaries to recruit AI researchers. But I asked Acemoglu about a different hiring spree I’ve noticed: AI companies are all building in-house economics teams.

OpenAI hired Ronnie Chatterji from Duke University in 2024 to be its chief economist and announced last year that Chatterji will work with Jason Furman—Harvard economist and former advisor to Barack Obama—to research AI and jobs. Anthropic has convened a group of 10 leading economists to do similar work. And just last week, Google DeepMind announced it had hired Alex Imas, an economist from the University of Chicago, to be its “director of AGI economics.”

Acemoglu has noticed colleagues getting snatched up for these roles too. “It makes sense,” he says: AI companies are well aware that public skepticism about AI, in large part due to job concerns, is growing. And they have strong incentives to shape the economic narrative around their technology (consider OpenAI’s latest proposal for a new era of industrial policy).

“What I hope we won’t get,” Acemoglu says, “is that they’re interested in economists just to further their viewpoints or further the hype.” That tension hangs over the emerging field of “AI economics”; it’s concerning that some of the most influential research about AI’s impact on work may increasingly come from the companies with the most to gain from favorable conclusions.

AI apps

I don’t think of AI as hard to use; most of us interact with it via chatbots that use plain language. But Acemoglu says we should consider how it compares with the sort of software that kicked off earlier tech transformations, like PowerPoint for slide decks and Word for documents. 

“Anybody could install these on their computer and get them to do the things that they want them to do,” he says. They spread accordingly. 

“We have not seen the development of apps based on AI that have the same usability,” he says. Even if anyone can chat with an AI model, it tends to take a while for the average worker to get practical and productive use out of it. That’s part of the reason why AI has not yet shown any seismic impact on the job market or the economy. One of the key signals Acemoglu is watching, then, is the creation of apps that make AI easier to use. 

But he acknowledges that for a while, we’re going to see all sorts of conflicting evidence about AI: anecdotes that college grads are finding the job market worse and worse, but no noticeable effect of AI on productivity, for example. “There’s a huge amount of uncertainty,” he says. And that’s the most telling thing about the AI economy right now: the certainty of the rhetoric alongside the uncertainty of everything else.

Fully Anonymized Digital Health Data Acquisition in a Research Partnership Using a Blinded Deidentification Proxy in the HerzFit App: Implementation Study

Background: The European General Data Protection Regulation (GDPR) strictly regulates the processing of personal and health-related data, posing challenges for digital health research, especially when data are collected using participants’ own devices. Although scientific data can theoretically be anonymized, standard internet communication protocols inevitably expose transmission metadata, preventing true anonymization. Existing solutions, including virtual private networks, reverse proxies, and trust centers, improve confidentiality but do not technically or legally enable fully anonymized data collection. Consequently, large-scale digital health research often requires extensive organizational measures, complex consent procedures, and high regulatory overhead. Objective: This study aimed to develop a GDPR-compliant concept for fully anonymized scientific data collection, ensuring that no entity has simultaneous access to identifying information and donated data. We also implemented and evaluated this concept in a real-world public-private partnership. Methods: We designed a data donation architecture based on a blinded deidentification proxy that decouples identifying transmission metadata from encrypted user data at the time of donation. The concept combines symmetric (Advanced Encryption Standard-128 in Cipher Block Chaining) and asymmetric (Rivest-Shamir-Adleman with Optimal Asymmetric Encryption Padding) encryption, enabling end-to-end encrypted and anonymized data transfer without persistent identifiers. The system was integrated into the HerzFit app, a mobile lifestyle coach for cardiovascular disease prevention available in German-speaking countries, and evaluated for adoption, technical feasibility, and performance. Performance overhead was assessed using round-trip time benchmarks. Duplicate donations were identified and merged to estimate unique data donors. Results: The solution was integrated and tested in the HerzFit app with more than 200,000 downloads between April 2022 and December 2025. Since the introduction of the data donation feature, more than 13,000 donations have been received, translating to more than 9000 individual users contributing anonymized datasets. Proxy-based transmission resulted in an average round-trip time of 143 ms, compared to 58 ms for direct transfer, representing a modest overhead while maintaining usability. The operator of the donation database did not gain access to identifying information at any stage, demonstrating full technical anonymization. The approach can be operated reliably at scale with minimal server resources due to the stateless proxy design. Conclusions: This work introduces a novel system architecture enabling fully anonymized, GDPR-compliant data donation directly from participants’ devices. By decoupling identifying metadata from encrypted health data, the concept minimizes regulatory effort, strengthens privacy protection, and provides a practical framework for large-scale digital health research in research partnerships, for example, between a private company and a research institution. The real-world deployment in HerzFit demonstrates the feasibility, scalability, and scientific utility of this approach. The concept is broadly transferable to other mobile health apps and has the potential to substantially expand ethically and legally compliant data acquisition.
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