STAT+: U.K. advocacy groups threaten court action over a key provision in the pharma trade deal with the U.S.

Two advocacy groups are demanding the United Kingdom revoke regulations at the heart of a new trade agreement with the U.S. over concerns the deal will allow outsiders to influence official decisions about the cost-effectiveness of medicines. And if the government does not comply, the groups are readying legal action.

Under the trade agreement that covers pharmaceuticals, which was finalized last month, the Trump administration committed to impose zero tariffs on medicines exported from the U.K. for at least three years. The deal is significant because it would make the U.K. the only country with tariff-free access for medicines to the U.S. market.

In return, the U.K. government took steps to appease the pharmaceutical industry, which is a key part of its economy, by pledging to increase spending on medicines from 0.3% of GDP to 0.35% by 2028 and then to 0.6% by 2035. At the same time, the U.K.’s National Health Service will increase the prices paid for by medicines by 25% and slash the maximum rebate it can claw back from drugmakers to 15%.

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In Ebola outbreak, a number of Americans in the Congo believed to have had exposure to suspected cases

A number of Americans who are in the Democratic Republic of the Congo are believed to have had exposure to suspected cases in the country’s latest Ebola outbreak, with several deemed to have had high-risk exposures, sources have told STAT. At least one of these individuals may have developed symptoms.  

One source said that there are not yet test results for any of the individuals, but the U.S. government is reportedly trying to arrange to transport them out of the DRC to somewhere they can be safely quarantined, and cared for, if they prove to have been infected. It’s not clear if that would be in the United States; there is some discussion of perhaps taking the individuals to an American military base in Germany, a source said.

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When should you get a mammogram? Conflicting advice makes it hard to know

WASHINGTON — Deciding when to get routine mammograms is confusing. Some health groups recommend women begin at age 40 or 45 while another recently opted for age 50. They also differ on whether yearly or every other year is best.

The conflicting advice is at least partly because guidelines for breast cancer screening are designed for women at average risk and with no possible cancer symptoms. But breast cancer is so common that it is hard to know who is really “average” and how to balance the pros and cons of screening.

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STAT+: The hantavirus outbreak is prompting Covid flashbacks — including the conspiracies

WASHINGTON — The deadly outbreak of a rare strain of hantavirus on a cruise has generated echoes of the pandemic era, including a reprise of a familiar drumbeat of questionable theories from social media personalities prominent for their Covid-19 skepticism.

At the moment, ironically, the public health establishment and the conspiracists challenging it actually seem to agree on the big picture: Hantavirus is not like the Covid-19 virus, and for now, the risk to the general public remains low.

But the speed at which a handful of people who became influential amid Covid-19 have begun recycling theories, from baseless suggestions about the origin of the current outbreak to unproven treatments, illustrates a new reality for any emerging public health threat.

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<![CDATA[Analysis of speech, acoustics, and facial cues reveals early psychosis and suicide risk.]]>
<![CDATA[Guidance on psychotropic meds in pregnancy: personalize decisions, coordinate care, and plan early to prevent postpartum relapse.]]>
<![CDATA[Studies link compassion and wisdom to less loneliness and richer gut microbiome diversity, pointing to gut–brain targets for mental health interventions.]]>

STAT+: Sen. Bill Cassidy loses primary as race heads to run-off in win for Trump

Bill Cassidy, a key Republican health care leader in the Senate, will lose his seat, as Louisiana’s Senate primary heads for a runoff between state treasurer John Fleming and Rep. Julia Letlow, who won President Trump’s endorsement.

In initial election results, Letlow leads with just over 44% of the vote, followed by Fleming with just over 28% percent of the vote. Cassidy came in at 24.8% of the vote. The president has endorsed Letlow, a Trump loyalist who became a proponent for the Covid-19 vaccine in 2021 following the death of her husband to Covid. 

Cassidy’s defeat is a win for President Trump and his allies, who have criticized the senator for voting in 2021 to convict the president for inciting the January 6 insurrection. Later, Cassidy came into conflict with the administration when he expressed concerns with anti-vaccine statements made by then-health secretary nominee Robert F. Kennedy Jr. before ultimately voting to confirm him

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WHO declares Ebola outbreak an international public health emergency

The World Health Organization late Saturday declared the outbreak of Ebola that was first seen in the Democratic Republic of the Congo an international public health emergency, underscoring the concern about the spread of the virus as travel-related cases were reported in Kampala, the capital of Uganda.

The speed with which the emergency issuance was made — African health officials only confirmed the outbreak on Friday — is unusual. So too is the fact that WHO Director-General Tedros Adhanom Ghebreyesus issued the declaration without first seeking the advice of an expert panel, called an emergency committee.

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<![CDATA[GLP-1 drugs like semaglutide may curb alcohol and opioid cravings, as trials expand, combos emerge, and interaction risks surface.]]>