Radically different
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology.
What actually matters in AI right now? It’s getting harder to tell amid the constant launches, hype, and warnings. To cut through the noise, MIT Technology Review’s reporters and editors have distilled years of analysis into a new essential guide: the 10 Things That Matter in AI Right Now.
The list builds on our annual 10 Breakthrough Technologies, but takes a wider view of the ideas, topics, and research shaping AI, spotlighting the trends and breakthroughs shaping the world.
We’ll be unpacking one item from the list each day here in The Download, explaining what it means and why it matters. Read the full rundown now—and stay tuned for the days ahead.
As the conflict in Iran has escalated, a crucial resource is under fire: the desalinization technology that supplies water in the region.
President Donald Trump recently threatened to destroy “possibly all desalinization plants” in Iran if the Strait of Hormuz is not reopened. The impact on farming, industry, and—crucially—drinking in the Middle East could be severe. Find out why.
—Casey Crownhart
This is our latest story to be turned into an MIT Technology Review Narrated podcast, which we publish each week on Spotify and Apple Podcasts. Just navigate to MIT Technology Review Narrated on either platform, and follow us to get all our new content as it’s released.
The must-reads
I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.
1 An unauthorized group has reportedly accessed Anthropic’s Mythos
Users in a private online forum may have gained access. (Bloomberg $)
+ Anthropic said the model was too dangerous for a full release. (Axios)
+ Mozilla used it to find 271 security vulnerabilities in Firefox. (Wired $)
2 Meta will track workers’ clicks and keystrokes for AI training
Tracking software is being installed on workers’ computers.(Reuters $)
+ Employees are up in arms about the program. (Business Insider)
+ LLMs could supercharge mass surveillance in the US. (MIT Technology Review)
3 ChatGPT allegedly advised the Florida State shooter
About when and where to strike, and which ammunition to use. (Washington Post $)
+ Florida’s attorney general is probing ChatGPT’s role in the shooting. (Ars Technica)
+ Does AI cause delusions or just amplify them? (MIT Technology Review)
4 SpaceX has secured the option to buy AI startup Cursor for $60 billion
Or pay $10 billion for the work they’re doing together. (The Verge)
+ SpaceX made the deal as it prepares to go public. (NYT $)
+ Musk’s endgame for the company may be a land grab in space. (The Atlantic $)
5 The Pentagon wants $54 billion for drones
That would rank among the top 10 military budgets for entire nations. (Ars Technica)
+ Shoplifters could soon be chased down by drones. (MIT Technology Review)
6 Apple’s new chief hardware officer signals a sprint to build in-house chips
Apple silicon lead Johny Srouji has been promoted to the role. (CNBC)
7 China’s government is tightening its grip on AI firms that try to leave
It’s doing all it can to stop firms like Manus sending talent and research overseas. (Washington Post $)
8 The FBI is probing the deaths of scientists tied to sensitive research
Including a nuclear physicist and MIT professor shot outside his home. (CNN)
9 The US is accelerating research into psychedelic medical treatment
Including the mysterious ibogaine. (Nature)
+ But psychedelics are (still) falling short in clinical trials. (MIT Technology Review)
10 The first retail boutique run by an AI agent has opened—and it’s chaos
The San Francisco shop is reassuringly mismanaged. (NYT $)
Quote of the day
—Donald Trump pays a classy tribute to Tim Cook on Truth Social.
One More Thing
A US agency pursuing moonshot health breakthroughs has hired a researcher advocating an extremely radical plan for defeating death. His idea? Replace your body parts. All of them. Even your brain.
Jean Hébert, a program manager at the US Advanced Research Projects Agency for Health (ARPA-H), believes we can beat aging by adding youthful tissue to people’s brains. Read the full story on his futuristic plan to extend human life.
—Antonio Regalado
We can still have nice things
A place for comfort, fun and distraction to brighten up your day. (Got any ideas? Drop me a line.)
+ A Lego set was sent to the edge of space—and survived.
+ Go behind the scenes with Werner Herzog as he guides a new generation of filmmakers.
+ This video about enshittification perfectly captures the frustration of the degrading internet.
+ NASA’s latest deep-space capture offers a rare view of planetary systems in their absolute infancy.
WASHINGTON — Health secretary Robert F. Kennedy Jr. once said there are no vaccines that are safe and effective. On Wednesday, he seemed to have changed his tune.
Across two Senate hearings, Kennedy noted that as health secretary, he funded the development of new vaccines, green-lit new shots for patients, asserted flu vaccines are preventive care, and even urged “every child to get the MMR,” a shot he previously suggested wasn’t safe. Last week, he acknowledged the shot could have saved the life of a child who died of measles.
Kennedy’s agenda continues to make waves across American health care, as his department pursues a broad crackdown on alleged fraud and seeks to upend Americans’ relationship with ultra-processed foods, all after major cuts across health agencies and a reworking of vaccine policy. But the about-face expands to a number of core MAHA issues — chemicals in food and the government’s relationship with industry among them.
It comes as some leaders of the insurgent movement have grown skeptical of the administration they rallied to support, forcing the Trump administration to thread the needle between courting the MAHA base’s ongoing support and dropping MAHA priorities seen as impractical or politically unwise.
Washington state hospitals say their Medicare patients are waiting two to four times longer in some cases for procedures that are now subject to prior authorization under a new Medicare program.
The report from Sen. Maria Cantwell (D-Wash.) is among the first to document alleged patient harm stemming from the Centers for Medicare and Medicaid Services’ new Wasteful and Inappropriate Service Reduction, or WISeR, Model. Cantwell is one of several Democratic members of Congress who have been urging CMS to scrap the program, which launched Jan. 1.
Cantwell aired her concerns about WISeR to Health and Human Services Secretary Robert F. Kennedy Jr. at a Senate Committee on Finance hearing Wednesday. She said CMS is using artificial intelligence as a “denial device” and that patients are waiting weeks to get sign off for services that previously didn’t require approval.
A former tobacco industry executive has been appointed to senior leadership at the Centers for Disease Control and Prevention, alarming public health advocates and critics of industry influence on government.
Stephen Sayle, named in March as the CDC’s deputy director for legislative affairs, previously worked at Fontem Ventures, a subsidiary of the British multinational tobacco corporation Imperial Brands. Between 2017 and 2018, he was U.S. vice president of corporate affairs at Fontem, which is focused on non-combustible tobacco products like the e-cigarette brand blu and the oral nicotine pouch brand Zone.
Background: Telemedicine has become central to digital health strategies, yet the regulatory environment that shapes ethical safeguards and equitable access remains uneven and incompletely assessed across countries. Legal and normative instruments matter because they define requirements for privacy, consent, accountability, professional readiness, and barrier reduction. Objective: This study aimed to map the current global landscape of normative instruments related to telemedicine and identify which ethical and social safeguards are explicitly addressed, with particular attention to equity. Methods: We conducted a document analysis guided by the READ (ready the materials, extract data, analyze data, and distill findings) framework. From February 2024 to February 2026, we conducted a structured web-based search across all World Health Organization (WHO) member states with no language restrictions, using official government sources, statutory professional regulators, and institutional publication channels. Retrieval combined internal site searches, direct navigation, external search engine queries, and targeted snowball sampling to identify currently in-force instruments. Two researchers independently extracted and coded data using a predefined codebook. We operationalized 10 binary items covering regulatory presence and scope (questions 1 and 2), safeguards for data protection (question 3), consent and disclosure (questions 4 and 5), prior in-person prerequisites (question 6), monitoring (question 7), training requirements (question 8), and equity (questions 9 and 10). We summarized frequencies overall and stratified by WHO region and World Bank income group and conducted a qualitative thematic analysis of included normative instruments. Results: Of the 194 WHO member states, 81 (41.8%) had at least one current normative instrument related to telemedicine in force. Among these, 72.8% (59/81) defined telemedicine or telehealth. Data protection provisions were most common (73/81, 90.1%), followed by mandatory informed consent (n=71, 87.7%) and monitoring mechanisms (n=65, 80.2%). Fewer countries required disclosure of telemedicine limitations (n=36, 44.4%) or mandated telemedicine-specific training (n=26, 32.1%). Prior in-person consultation requirements were uncommon (n=8, 9.9%). Equity-related safeguards were uneven: 51.9% (n=42) referenced justice, equity, or nondiscrimination, whereas 30.9% (n=25) included concrete barrier reduction provisions (eg, digital inclusion or accommodations for people with disabilities and minors). Conclusions: Telemedicine regulation is becoming more common, but both coverage and safeguarding content remain uneven. While privacy, consent, and monitoring are frequently addressed where regulation exists, disclosure, physician competency, and operational equity measures are less consistently specified. Strengthening telemedicine governance will require translating ethical commitments into enforceable standards that address digital determinants of access and protect groups at risk of exclusion.
<img src="https://jmir-production.s3.us-east-2.amazonaws.com/thumbs/e7a1a08d85d00c323ddd2943c5eeeb00" />
Background: Mobile health (mHealth), and specifically smartphone apps, have grown exponentially in both functionality and accessibility and are becoming an important component of health care. Research exploring the use of mHealth for managing or treating chronic diseases, such as cancer, has shown promising effects. Yet, comparatively little work has examined how such technologies can enhance exercise interventions for young people with cancer. To optimize the effectiveness of mHealth in these contexts, it is essential to build a stronger evidence base on user experience. Objective: This study aimed to investigate how healthy children and young people engaged with an augmented reality (AR) app developed specifically for children and young people undergoing cancer treatment, and to identify design features that may support engagement and behavior change in the intended clinical population. Methods: School and university students, aged 8‐21 years, were eligible to participate in the study. Practical workshops allowed participants to engage with the AR exercise app before taking part in focus groups to explore user experiences. Data were analyzed using qualitative content analysis, which also involved a critical friend approach using 2 researchers (HM and KS). Suggested improvements were mapped against the motivational affordances’ taxonomy. Results: A total of 39 participants aged 8‐21 years took part in the focus group study. Participants found the demonstrations and varied exercises useful but expressed some concerns regarding data safety and functionality of the novel AR avatar. It was proposed that additional educational components, challenges, and rewards, as well as a customizable avatar, social support features, and audio instructions for a more inclusive design would be desirable and could enhance user experience. When mapped against the motivational affordances taxonomy, the suggested improvements aligned primarily with mechanisms of user education, challenges, feedback, cooperation, and comparison. Conclusions: This study provides an understanding of how apps that prescribe exercise can be optimized to enhance motivation and user experience. By assessing feedback and suggestions for improvements, the findings highlight key design features that may support engagement. While this initial work focused on healthy, age-matched participants, further evidence specifically in children and young people with a childhood cancer diagnosis is needed. International Registered Report Identifier (IRRID): RR2-10.1177/14604582241288784
<img src="https://jmir-production.s3.us-east-2.amazonaws.com/thumbs/672e136cdb9160f2425765e861564c3e" />
Formative evaluation is widely used in implementation science to anticipate barriers and facilitators prior to the deployment of health technologies, typically relying on stakeholders’ reported beliefs collected before real-world exposure. This approach has proven informative for many digital health tools; however, its application to immersive and embodied technologies such as extended reality (XR) warrants closer scrutiny. Most XR interventions in health care are delivered through head-mounted displays, which depend on spatial perception and sensorimotor engagement. Several implementation-relevant properties, including comfort, perceived intrusiveness, safety, and workflow disruption, often become apparent only through direct interaction. At the same time, large segments of the health care workforce remain XR-naive, such that preuse judgments are frequently shaped by anticipation rather than experience. Drawing on concepts from implementation science, grounded cognition, and human-computer interaction, this Viewpoint examines a plausible interpretive problem in XR adoption and argues that perception-based formative evaluation, when applied through frameworks developed for screen-based technologies, may misclassify barriers and facilitators. Rather than questioning formative evaluation as a methodological approach, we identify a boundary condition for its interpretability in experience-dependent technologies and propose a pragmatic refinement: incorporating brief experiential familiarization before eliciting stakeholder perceptions to strengthen early-stage assessment and improve alignment with real-world implementation decisions.
<img src="https://jmir-production.s3.us-east-2.amazonaws.com/thumbs/6b17c7f022153c7e3d6256671daa9279" />
