NHS SBS and Salesforce launch AI finance support platform
Tailored Brain Health Insights Through Nurturing Knowledge-based Change – Stakeholder-driven, Human-centered, AI-powered Refinement for Prevention
Interventions: Behavioral: BLAZE (Brain health Lifestyle Action with personaliZed Engagement)
Sponsors: Alexandra Hospital; National University Hospital, Singapore; National University Polyclinics, Singapore
Not yet recruiting
STAT+: As Ebola outbreak in Central Africa grows, the U.S. turns itself into a fortress
When Craig Spencer contracted Ebola while working in Guinea during the West African outbreak in 2014, he was already back in the United States when he first developed symptoms. He credits the treatment he got at New York’s Bellevue Hospital for his survival.
If Spencer, an emergency medicine physician and an associate professor in Brown University’s School of Public Health, were to contract Ebola in the current outbreak in the Democratic Republic of Congo and Uganda — if he’d even had high-risk exposures to Ebola patients — he wouldn’t be allowed back into the U.S. for care or quarantine.
Administration officials confirmed Thursday that any Americans who contract Ebola will not be brought to the United States for treatment. Instead, they will be evacuated to as-yet-undetermined locations in Europe. An official, speaking on condition of anonymity, told reporters that the Centers for Disease Control and Prevention and the State Department are working to identify tertiary care facilities that could take Americans needing care. One such case has already occurred.
System C completes Badgernet maternity rollout in Wales
Stress Management and Meditative Movements for Asian Americans With Depression and Physical Symptoms
Interventions: Behavioral: Stress Management and Resiliency Training with Qigong/Tai Chi; Behavioral: Healthy Living Program
Sponsors: Massachusetts General Hospital; National Center for Complementary and Integrative Health (NCCIH)
Not yet recruiting
EEG Prediction and Clinical Efficacy of tDCS in Major Depression
Interventions: Device: High-dose home-tDCS; Device: Conventional home-tDCS
Sponsors: Ionclinics & Deionic SL; Hospital Universitario Doctor Peset; Universidad Europea de Valencia
Not yet recruiting
Artificial Intelligence-driven Tuberculosis Landscape Analysis & Stratification Research
Sponsors: Huashan Hospital; The Hong Kong Polytechnic University
Not yet recruiting
Immune Repertoire Decoding for Chronic Pancreatitis-to-Pancreatic Cancer Risk Stratification
Sponsors: Changhai Hospital
Not yet recruiting
Real-World Implementation of EndoConnect in Brazilian Primary Care: Formative Study of Usability, Engagement, and Equity in Digital Endometriosis Care
Background: Endometriosis is a chronic gynecological condition affecting approximately 10% of women of reproductive age worldwide and is associated with chronic pelvic pain, infertility, and reduced quality of life. In Brazil’s Unified Health System (Sistema Único de Saúde [SUS]), diagnostic delays frequently range from 7 to 10 years and disproportionately affect socially vulnerable populations, including rural, low-income, Black, and Indigenous women. Digital health interventions have been proposed as scalable solutions; however, most available applications are developed in high-income settings and do not align with the structural and operational realities of low- and middle-income countries (LMICs). Objective: This study aimed to evaluate feasibility, usability, acceptability, and user engagement associated with the real-world implementation of EndoConnect Alpha in primary health care settings, and to explore preliminary patterns of change in symptom burden, knowledge, and care navigation. Methods: A single-arm, prospective, formative implementation study was conducted in 10 primary health care units in Ceará, Brazil. A convenience sample of 60 participants, including women with suspected or confirmed endometriosis and primary care professionals, used the platform over an 8-week period under real-world conditions. Usability (assessed using the System Usability Scale), acceptability (assessed using the Technology Acceptance Model), engagement metrics, and exploratory outcomes were assessed. All analyses were exploratory, with no control group and no causal inference. Results: High usability and acceptability were observed, with strong user engagement, including a 79% completion rate of educational modules and consistent platform use. Observed decreases in pelvic pain and anxiety were identified, alongside increases in disease-related knowledge, self-reported therapy adherence, and reported gynecological referrals. A positive association between usability and acceptability was also observed. These findings should be interpreted as exploratory signals given the study design. Descriptive subgroup analyses suggested more pronounced trends among rural participants and those with a lower education level. Conclusions: The real-world implementation of EndoConnect Alpha demonstrated high feasibility, usability, and acceptability within a public primary care setting in a middle-income country. Observed trends suggest potential benefits, particularly among underserved populations; however, causal inference cannot be established. These findings support further controlled evaluation and highlight the relevance of equity-oriented digital health strategies tailored to LMIC contexts.
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