Psychological function in the context of protracted stress during war: a multi-sample, multivariate longitudinal study
Cyclothymic and anxious affective temperament in perinatal depression: findings from an exploratory cross-sectional study
Auditory processing and communication in autism: exploring verbal abilities and vocal affective cues
Association between the geriatric nutritional risk index and postoperative delirium: a meta-analysis
High-fidelity intravital imaging of biological dynamics with latent-space-enhanced digital adaptive optics
Nature Biotechnology, Published online: 23 April 2026; doi:10.1038/s41587-026-03107-2
Intravital imaging is improved by applying deep learning to wave-optics modeling.
Genome editing of phylogenetically distinct bacteria using cross-species retron-mediated recombineering
Nature Biotechnology, Published online: 23 April 2026; doi:10.1038/s41587-026-03076-6
Retron-based systems for genome editing are functional across bacterial species.
How to meaningfully evaluate AI in clinical medicine
Nature Medicine, Published online: 23 April 2026; doi:10.1038/s41591-026-04350-5
How to meaningfully evaluate AI in clinical medicine
Africa’s moment for health security
Nature Medicine, Published online: 23 April 2026; doi:10.1038/s41591-026-04330-9
Advancing pandemic readiness to secure Africa’s health sovereignty.
Intestinal metaplasia is the only precursor to esophageal adenocarcinoma
Nature Medicine, Published online: 23 April 2026; doi:10.1038/s41591-026-04332-7
We integrated large-scale epidemiological and genomic data from patients with esophageal adenocarcinoma to compare cancers with and without Barrett’s esophagus (BE). We found shared risk factors, molecular features, evolutionary trajectories and BE lineage markers in both cancer phenotypes. Our findings support a single intestinal metaplasia-mediated pathway and have direct implications for early detection and prevention strategies.

