News Approved - Relatix Health

April 3, 2026

Efficacy of Spectrally Optimized Light on Cognitive Impairment in Major Depressive Disorder and Its Neuroimaging Mechanisms

Conditions: Major Depressive Disorder (MDD); Neuroimaging; Bright Light Treatment; Cognitive Impairment

Interventions: Device: bright light; Device: dim red light(placebo)

Sponsors: Peking University Sixth Hospital

Not yet recruiting

April 3, 2026

The exposome of brain aging across 34 countries

Nature Medicine, Published online: 03 April 2026; doi:10.1038/s41591-026-04302-z

Exposome analyses across 34 countries showed that social exposures were associated with faster functional brain aging and physical exposures with faster structural brain aging.

April 3, 2026

Optimized, Neuroplasticity-Enhanced-Depression (ONE-D) Transcranial Magnetic Stimulation (TMS) Treatment for Female Athletes With Co-morbid Depression and Concussion

Conditions: Concussion; Depression

Interventions: Device: ONE-D TMS protocol and d-cycloserine (125 mg)

Sponsors: University of Florida

Not yet recruiting

April 3, 2026

CARED : A Novel Rapid Treatment Paradigm for Depression

Conditions: Major Depressive Disorder

Interventions: Device: Intermittent Theta Burst Stimulation (iTBS); Device: Transcranial Alternating Current Stimulation (tACS); Behavioral: Psychotherapy; Device: Sham (Placebo) Transcranial Alternating Current Stimulation (tACS)

Sponsors: University of North Carolina, Chapel Hill; Foundation of Hope for the Research and Treatment of Mental Illness

Not yet recruiting

April 3, 2026

Target product profiles for treatments to delay or prevent symptomatic Alzheimer’s disease

Nature Medicine, Published online: 03 April 2026; doi:10.1038/s41591-026-04305-w

To accelerate therapeutic development and equip stakeholders with clear benchmarks, the authors outline target product profiles for therapies designed to delay or prevent the onset of clinical symptoms of Alzheimer’s disease.

April 3, 2026

Efficacy and Influencing Factors of Mindfulness-Based Exposure Group Therapy for OCD

Conditions: Obessive-Compulsive Disorder

Interventions: Behavioral: mindfulness based exposure therapy; Other: Treatment as Usual (TAU)

Sponsors: Shanghai Mental Health Center

Recruiting

April 3, 2026

Improving Caregiver Engagement in Early Interventions

Conditions: Autism

Interventions: Behavioral: FANS-EI; Behavioral: Early Intervention

Sponsors: University of California, Davis; National Institute of Mental Health (NIMH)

Not yet recruiting

April 3, 2026

Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital

Conditions: Psychiatric Disorders; Depression – Major Depressive Disorder; Schizophrenia and Other Psychotic Disorders; Anxiety and Mood Disorders; Bipolar and Related Disorders; PTSD – Post Traumatic Stress Disorder; Autism Spectrum Disorder

Interventions: Behavioral: Action-Based Cognitive Remediation

Sponsors: The Royal Ottawa Mental Health Centre

Not yet recruiting

April 3, 2026

Safety Planning Intervention for Autistic Youth: A Randomized Controlled Trial With Providers in Developmental-Behavioral Pediatric Clinics

Conditions: Autism; Suicide Prevention

Interventions: Behavioral: Safety Planning Intervention; Behavioral: Crisis Interventions for Pediatric Providers – Autism version (CIPP-A)

Sponsors: Children’s Hospital Los Angeles; Children’s Hospital of Philadelphia

Not yet recruiting