<![CDATA[Why teens use drugs and alcohol: avoidant attachment and emotional isolation fuel addiction; attachment-based therapy rebuilds bonds and cuts relapse.]]>
<![CDATA[Top 2026 psychiatry conference takeaways: mixed-feature bipolar care, GLP-1 addiction trials, schizophrenia adherence, TD gaps, AI prodrome screening.]]>

Development and validation of the digital well-being scale using university students

IntroductionDigital technologies are central to university students’ academic, social, and personal lives, offering opportunities for learning and connection while also introducing challenges such as distraction, emotional strain, and difficulties with self-regulation. Despite increasing interest in digital well-being, there is a lack of comprehensive, psychometrically sound instruments specifically designed to assess digital well-being among university students. This study developed and validated the Digital Well-Being Scale (DWS) for use in higher education.MethodsA cross-sectional survey was conducted among 1,533 undergraduate and postgraduate students from a public university in Ghana. Scale development involved literature review, expert evaluation, pilot testing, and psychometric validation. Exploratory factor analysis (EFA) was used to identify the underlying factor structure, followed by confirmatory factor analysis (CFA) to evaluate construct validity. Reliability, convergent validity, discriminant validity, and measurement invariance across gender were also assessed.ResultsEFA supported a six-factor solution comprising Task Interference, Digital Safety and Responsible Use, Perceived Control and Satisfaction, Digital Life Balance, Emotional Regulation, and Digital Dependence and Frustration. Following CFA-based refinement, a 41-item scale was retained. The six-factor first-order model demonstrated excellent fit to the data and outperformed a higher-order model. The DWS showed satisfactory internal consistency, convergent validity, and discriminant validity across all dimensions. Measurement invariance analyses supported configural and metric invariance across gender, although scalar invariance was only partially supported.DiscussionThe DWS provides a theoretically grounded and psychometrically robust multidimensional measure of digital well-being among university students. The findings suggest that digital well-being encompasses behavioural, emotional, cognitive, self-regulatory, and responsible dimensions of digital engagement rather than representing a single, unidimensional construct. The scale offers a valuable tool for research, screening, and intervention aimed at understanding and promoting digital well-being and digital mental health in higher education settings.

Quitting smoking is hard. A Medicare change may push doctors to give more help

Pretty much everyone who cares about public health agrees that it’s a good idea to help people quit smoking, the No. 1 cause of preventable death in the U.S. Doctors may soon get some extra encouragement to lend a hand, thanks to proposed changes in Medicare’s physician fee schedules.

Physicians who offer counseling on quitting cigarettes or other tobacco products during visits with patients would get a 19% increase in reimbursement, according to a few paragraphs buried in the 1,592-page document released this week. The same adjustment would also apply to assessments of, and interventions for, alcohol and substance misuse during doctors’ visits.

“Given the evidence supported role these services play in preventing and managing chronic disease […] we believe that valuation should more accurately reflect the clinical intensity and work associated with these time-based services,” the proposal from the Centers for Medicare and Medicaid Services explains. Comments on the proposal are due Sept. 14. 

“The prioritization of cessation as a service is long overdue, and we’re very excited about it,” said Anne DiGiulio, the American Lung Association’s senior director of nationwide tobacco cessation and health policy.

Read the rest…

<![CDATA[Learn how clinicians tackle mood and substance use disorders together, boost patient engagement, and expand evidence-based addiction medications for bipolar and alcohol use.]]>

Physical education performance as a protective pathway: breaking the cycle between learning burnout and gaming disorder in Chinese adolescents

Background and AimsGaming disorder (GD) and learning burnout (LB) are critical issues impacting adolescents, with GD recognized by the World Health Organization as a behavioral addiction and LB contributing to academic disengagement. While prior research has examined bivariate relationships, such as GD’s negative correlation with academic performance and physical education performance, or LB’s association with poor grades, no study has integrated all four variables into one model to explore their dynamic interactions longitudinally.MethodsA cross-lagged panel network (CLPN) model was applied to longitudinal data from 811 Chinese middle school students collected at two time points.ResultsGD and LB showed minimal direct effects on academic performance or physical education performance. Instead, academic performance and physical education performance acted as protective factors, significantly alleviating LB, particularly among boys. These two protective factors were mutually reinforcing. Cognitive exhaustion (a core component of LB) and GD functioned as reciprocal risk factors.ConclusionInterventions for adolescent maladjustment should prioritize addressing learning burnout through academic and physical avenues rather than overemphasizing gaming disorder, with tailored strategies for different genders.

Strategic Planning for a Digital Health Innovation Hub at a Saudi Academic Medical Center: Qualitative Case Study

Background: Rapid digital transformation is reshaping health care, but many digital initiatives struggle to deliver sustained organizational value when they are introduced as stand-alone technologies rather than as part of an institutional strategy. In Saudi Arabia, Vision 2030 has intensified pressure on academic medical centers to strengthen digital capability, localize innovation, and reduce dependence on externally driven solutions. Objective: This study aimed to examine organizational factors shaping digital health innovation at King Saud University Medical City (KSUMC) and to develop a preliminary strategic planning framework for a digital health innovation hub tailored to that setting. Methods: We conducted a qualitative exploratory case study at KSUMC between April and June 2025. Fourteen stakeholders from clinical, administrative, research, governance, educational, and innovation-related roles were recruited using maximum variation purposive sampling. Semistructured interviews were audio-recorded, transcribed verbatim, and analyzed using reflexive thematic analysis. Reporting was guided by the COREQ (Consolidated Criteria for Reporting Qualitative Research). Diffusion of innovation theory and systems thinking informed interpretation, while a context-actor-mechanism-outcome lens was used to examine how institutional conditions shaped innovation processes. No patient data were collected. Results: Five interrelated themes were identified. First, leadership support existed at a symbolic level, but middle-management translation and risk tolerance were inconsistent. Second, innovation was constrained by workload, fragmented systems, and weak operational support, which meant that project work was often treated as discretionary rather than embedded. Third, knowledge transfer and commercialization pathways were fragmented; participants repeatedly described unclear routes from idea generation to prototyping, regulatory review, and market engagement. Fourth, incentives and innovation capability were misaligned with institutional expectations, particularly for clinicians and trainees. Fifth, Vision 2030 created strategic legitimacy and momentum, but participants also cautioned that an overreliance on consultant-led or vendor-led approaches could weaken internal capability building. These findings informed a preliminary framework centered on governance, knowledge transfer, partnership structures, workforce development, and phased implementation rather than a validated institutional model. Conclusions: At KSUMC, digital health innovation is shaped not only by technology availability but also by organizational culture, intermediary structures, governance design, and the extent to which innovation work is made operationally feasible. The framework proposed here should therefore be understood as a preliminary planning model derived from one qualitative case study. Its main contribution is to specify how knowledge transfer, commercialization, and institutional capability building can be integrated into a digital health strategy within a Saudi academic medical center.
<img src="https://jmir-production.s3.us-east-2.amazonaws.com/thumbs/85d230b912fdefe6673792b1fe27c5d2" />

The Download: a donor conception cap and world models for AI

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology.

Sperm donors need limits, says a European fertility group

Ties van der Meer doesn’t know how many siblings he has. The 47-year-old was conceived at a private fertility clinic using sperm from an anonymous donor. He eventually tracked down one sibling, but he may have others he’ll never find. 

Other donor-conceived people have found they have tens or even hundreds of them. “It does make you feel a bit mass-produced,” said one who discovered they had 25 half-siblings.

In response, a European fertility organization says we need international limits on the number of children a single donor can contribute to. 

Find out what their proposal could achieve—and where it may fall short. 

—Jessica Hamzelou

This story is from The Checkup, our weekly biotech newsletter. Sign up to receive it in your inbox every Thursday.

How will AI understand the real world?

LLMs have transformed what AI can do with language, but helping machines understand and operate within physical spaces presents a different challenge. In response, researchers are developing a new form of artificial intelligence: world models.

At a LinkedIn Live event tomorrow, MIT Technology Review will explore how this technology could shape the future of robotics and open one of AI’s next major frontiers. Join Will Douglas Heaven, our senior editor for AI, and Sam Sinha, founding AI researcher and head of world models at 1X Technologies, for the conversation on Tuesday, July 14. 

Register here to attend the free session at 9:30 PDT, 12:30 PM EDT, and 5:30 PM BST. 

The must-reads

I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.

1 Apple has sued OpenAI for allegedly stealing trade secrets
OpenAI purportedly stole IP to develop its own consumer hardware. (CNBC)
+ The suit claims OpenAI poached Apple staff to access the information. (BBC)
+ And requested trade secrets in job interviews with Apple workers. (Guardian)
+ Apple also sued two former employees, Chang Liu and Tang Tan. (Reuters $)

2 A Nobel-winning chemist is leaving the US to lead an AI lab in China
Omar Yaghi will head an institute using AI to discover new materials. (LA Times $)
+ He won a Nobel Prize in Chemistry for creating “molecular sponges.” (NYT $)
+ His departure comes as China tries to woo US scientists. (Nature)
+ The White House has slashed science spending. (MIT Technology Review)
 
3 The EU is moving closer to banning children from social media
It’s proposed barring under-13s unless supervised by an adult. (NYT $)
+ And limiting access for older children. (Bloomberg $)
+ The EU has also told Meta to disable autoplay and infinite scroll. (Politico $)
 
4 Meta scrapped an AI image feature on Instagram after a backlash
It allowed users to generate images based on public accounts. (TechCrunch)
+ And automatically opted in any Instagram user with a public account. (NYT $)
+ AI memories are privacy’s next frontier. (MIT Technology Review)
 
5 Phoebe Gates’ shopping app claimed credit for sales it didn’t drive
Phia claimed unearned affiliate sales through fake clicks. (Bloomberg $)
+ Cofounder Gates is the daughter of Microsoft cofounder Bill. (Engadget)
 
6 Leaked police drone footage exposes the new reality of surveillance
Hours of San Francisco Police video were accidentally released. (Wired $)
+ Surveillance from drones is on the rise in the US. (MIT Technology Review)
 
7 Over two-thirds of Americans back a Sanders-style AI ownership plan
A poll found strong support for public ownership of AI stock. (Gizmodo)
+ Tech firms have their own takes on the idea. (MIT Technology Review)

8 AI may soon make campaign text messages more potent—and irritating
AI platforms are training bots to sound like political candidates. (NPR)

9 An orbiting disco ball gave Einstein’s theory its most precise test yet  
It measured Earth’s twisting of space-time more precisely. (Rest of World)

10 Australia’s biggest radio hit may be the product of GenAI
Musicians are questioning how the song was made. (Guardian)

Quote of the day

“LOL, I found out I can access the [network storage], so funny.” 

—A text message sent by former Apple engineer Chang Liu to a colleague, which a new lawsuit alleges was part of a scheme to steal hardware IP for OpenAI.

One More Thing

view of an unmanned sub from the nose
Colombian military officials intercepted this 40-foot-long uncrewed fiberglass “narco sub” in the ocean just off Tayrona National Park.
CARLOS PARRA RIOS


How uncrewed narco subs could transform the Colombian drug trade

On a bright April morning in 2025, a surveillance plane operated by the Colombian military spotted a 40-foot-long “narco sub” idling in the Caribbean Sea. The stealthy vessel, used by drug cartels to move cocaine north, could sail with its hull almost entirely underwater.

After seizing the boat, the coast guard noticed something unusual: there was no one on board. This was Colombia’s first confirmed uncrewed narco sub, operable by remote control, but also capable of a degree of autonomous travel.

Uncrewed subs could move more cocaine over longer distances, and they won’t put human smugglers at risk of capture. Find out how they may transform the drug trade.

— Eduardo Echeverri López

We can still have nice things

A place for comfort, fun, and distraction to brighten up your day. (Got any ideas? Drop me a line.)

+ Metallica’s “Enter Sandman” has been reinvented as a yacht rock track.
+ Two super-puff planets lighter than cotton candy have been spotted floating through space.
+ An inventor has given Tic Tac fans (like Donald Trump) a solution to the box’s annoying rattling in their pockets.
+ Imbibe a dose of adrenaline with this first-person footage of a rider on heart-pounding Red Bull Genova Cerro Abajo.

Treating addiction with an addictive drug: the ketamine paradox revisited

BackgroundSubstance use disorders (SUDs) and treatment-resistant depression (TRD) remain a major global health challenge, marked by high relapse rates and limited long-term effectiveness of existing treatments. Ketamine, a glutamatergic modulator with rapid neuroplastic effects, has emerged as a novel intervention for TRD and is increasingly investigated as an adjunctive treatment for addiction, yet concerns about its abuse liability persist.ObjectiveThis review critically evaluates ketamine’s therapeutic potential for SUDs while examining its neurobiological mechanisms, clinical efficacy, and risk of misuse within a unified risk–benefit framework.MethodsA structured narrative review conducted in accordance with the SANRA framework using the PubMed, Scopus, PsycINFO, and Web of Science databases, covering literature published until March 2026. Eligible studies included clinical trials, experimental studies, and mechanistic investigations relevant to ketamine use in addiction and depression. Evidence was synthesized thematically across the domains of efficacy, mechanisms, and safety.ResultsAcross alcohol and cocaine use disorders, ketamine combined with psychotherapy has demonstrated promising reductions in craving and increases in abstinent days in small-to moderate-sized Phase 2 trials. However, findings remain difficult to generalize due to considerable variability in dosing strategies, comparator conditions, and follow-up periods. Effects on relapse prevention have been more inconsistent and less reliably positive. Mechanistically, ketamine promotes synaptic plasticity via NMDA receptor antagonism and downstream glutamatergic signaling, potentially disrupting maladaptive reward-related memories and reversing maladaptive neurocircuitry involved in both depression and addiction. While acute adverse effects are generally transient under clinical supervision, ketamine carries a well-established risk of misuse, particularly in unsupervised or high-dose settings.ConclusionsKetamine represents a promising but still experimental intervention for both refractory depression and selected SUDs. Its clinical use depends on careful patient selection, structured delivery, and integration with psychotherapy. Although ketamine may redefine treatment paradigms for TRD and addiction, larger-scale trials and long-term safety data are essential to define its role within psychiatric and addiction treatment frameworks.

Case Report: Delirium and complications resulting from the abuse of compound liquorice tablets

BackgroundCompound liquorice tablets is a cough-suppressing compound formulation containing opium powder and liquorice. With the strict regulation of traditional opioids, this medication has emerged as a novel alternative for substance abuse due to its easy accessibility and low cost; however, its addiction potential and severe adverse complications remain underrecognized and insufficiently addressed in clinical practice.Case summaryThe patient is a 29-year-old male who began self-medicating with compound liquorice tablets for a dry cough after COVID-19 infection. His daily dosage gradually escalated to 200–600 tablets within two years, resulting in established drug dependence. Two days after discontinuing the medication, he developed delirium manifested as confusion, disorientation, visual hallucinations and psychomotor agitation, accompanied by palpitations, hypertension, tremors, rhinorrhea, vomiting, severe hypokalemia, and bilateral lower limb edema. Organic brain diseases were excluded by systematic examinations. According to the ICD-10 diagnostic criteria, he was diagnosed with opioid-induced mental and behavioral disorders, hypokalemia and hypertension. We implemented a benzodiazepine tapering regimen to control delirium and sympathetic excitation associated with withdrawal symptoms, combined with antidepressants and antipsychotics to improve mood, anxiety, and psychotic symptoms, Under the guidance of a cardiologist, we actively managing hypertension and correcting internal environmental disturbances. Following comprehensive management, the patient’s withdrawal symptoms and delirium resolved, with stable emotional state and blood pressure, resulting in successful withdrawal.ConclusionThis is the first reported case of delirium caused by withdrawal from compound liquorice tablets. It provides preliminary insights for clinical identification, diagnosis, and multidisciplinary management of dependence on compound liquorice tablets, as well as related withdrawal symptoms and complications. This case also alerts to the emerging risk of abuse associated with new substances such as compound liquorice tablets and underscores the need for stricter prescription controls and patient education regarding the risks of abuse.