STAT+: Pharmalittle: We’re reading about Trump’s drug tariffs, a U.S.-U.K. pharma trade deal, and more

And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is rather modest so far. We plan to tidy up around the castle, promenade with the official mascots, and catch up on our reading. We also plan another listening party, where the rotation will likely include this, this, this, this and this. And what about you? The change of seasons opens up all sorts of possibilities, from long walks through woods to strolling along city streets to drives through the countryside. Of course, if the weather fails to cooperate, you could open a book, watch the telly, or spin a platter and dance about. Or maybe it is an opportunity to connect with someone special. Well, whatever you do, have a grand time. But be safe. Enjoy, and see you soon. …

The Trump administration announced 100% tariffs on imported brand-name drugs — but with significant caveats, STAT explains. Many large drugmakers will not have to pay the tax because they struck deals with the U.S. to build manufacturing facilities here and lower the prices of their medications. Drugmakers that have not struck such deals but pledge to bring production to the U.S. can have tariffs reduced to 20% for the remainder of Trump’s term. The tariffs open a new front in the Trump administration’s efforts to rein in the pharmaceutical industry and in its push to bring manufacturing back to the U.S. The announcement comes as Trump has looked to emphasize his administration’s work to make prices — especially for medicines — more affordable ahead of the midterm elections.

Meanwhile, the Trump administration is negotiating more drug-pricing deals, now with smaller companies, according to STAT. The new talks offer a pathway for smaller pharmaceutical companies — those not included in the first round of deals — to pledge lower prices and potentially avoid tariffs or new pricing policies through Medicare. The negotiations suggest the administration is looking to replicate the strategy it used with larger drugmakers: extract voluntary, confidential agreements in pursuit of lower prices and more domestic manufacturing. They also offer smaller players in the sector the chance to cut a deal and gain more certainty about how they might be affected by federal policies. But the number of companies in talks with the administration remains unclear, as does whether or when the sides will reach agreement.

Continue to STAT+ to read the full story…

Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers

Conditions: Skin and Connective Tissue Diseases; Neglected Tropical Diseases; Leprosy; Buruli Ulcer; Cutaneous Leishmaniasis; Scabies; Mycetoma; Lymphatic Filariasis; Onchocerciasis; Tungiasis; Post Kala-Azar Dermal Leishmaniasis; Yaws; Podoconiosis

Interventions: Device: A mobile app with AI functionality for diagnosing skin-related NTDs

Sponsors: Kenya Medical Research Institute; Universidad Politecnica de Madrid; FACHHOCHSCHULE ZENTRALSCHWEIZ – HOCHSCHULE LUZERN; SHERWOOD HEALTHCARE SENEGAL SARL; King’s College London; TEACUP CONSULTING SL; MTU AUSTRALO ALPHA LAB; OMODI, AGASNA, ODIEMBO ADVOCATES LLP; OEUVRES HOSPITALIERES FRANCAISES DE L’ORDRE DE MALTE; ARMAUER HANSEN RESEARCH INSTITUTE; Leprosy and Tuberculosis Relief Initiative Nigeria; UNIVERSITE CATHOLIQUE DE BUKAVU

Not yet recruiting

CFT Guided Self-help Intervention: Parents of Autistic Children

Conditions: Autism Disorders and Maternal Stress; Autism; Autism Disorder; Autism Spectrum Disorder; Autism in Children; Parent; Parent Mental Health; Parent Stress; Parent Support

Interventions: Other: Guided, self-help compassion-focused intervention for parents of autistic children

Sponsors: University of Nottingham; University Hospitals of Derby and Burton NHS Foundation Trust; Lincolnshire Partnership NHS Foundation Trust

Not yet recruiting

Relatix Health Applies for ARIA Funding to Build Digital Trust for Neurodiverse Communities

We’re proud to share that Relatix Health has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under its Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds, and we believe that conversation must include people whose minds work differently.

Our proposal focuses on one of the most pressing and least understood challenges of the digital age: how people with neurodevelopmental and neurodiverse conditions, including autism, ADHD, schizophrenia, borderline traits, and psychopathy, experience, interact with, and build trust in AI systems. In a world increasingly mediated by algorithms, the ways these systems interpret, respond to, and store our most personal thoughts and data matter profoundly.

Throughout history, individuals living with stigmatized neurocognitive conditions have been marginalized or misrepresented by institutions, by society, and now, potentially, by AI. Some may over-trust technology that feels neutral or supportive; others may under-trust it because of past harm or bias. We want to ensure that digital systems meet people where they are, building trust rather than eroding it, while protecting privacy and supporting quality of life, health, and wellbeing.

Through this work, Relatix Health aims to lead the way in ethical and inclusive neuro-AI design: protecting privacy, reducing stigma, and helping define standards for responsible data handling in the era of AI. Our goal is to make sure that the next generation of AI-driven tools, from chatbots to diagnostics, truly serves everyone, regardless of how their brain is wired.

We know how often things have already gone wrong, from chatbots unintentionally encouraging depressive or paranoid thoughts, to credit and gambling platforms optimizing for addiction or impulsive behaviour. These systems were not built with sufficient safeguards for people with neurodevelopmental conditions, who may react differently to AI-optimized interactions. Many respond by disengaging digitally, and may feel that an AI-driven world is a minefield because it was not built for them.

Join us in shaping a radically different future where cognitive diversity and digital trust can coexist, and AI tools are built to truly support and empower. To learn more about our mission or to collaborate, contact our team.