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UCSD, IGI Partnership Expands CRISPR Innovation Across Health, Agriculture, and the Environment
UC San Diego has joined the Innovative Genomics Institute as its fourth UC partner, expanding collaboration to develop next-generation genome-editing technologies that address major health, climate, agriculture, and environmental challenges through interdisciplinary research. The…
Diagnostic Discrimination of BOKE STARS, a Bimodal Continuous Performance Test, for Attention-Deficit/Hyperactivity Disorder Assessment in Chinese Children: Single-Center Case-Control Study
Background: Attention-deficit/hyperactivity disorder (ADHD) affects 6.3% of Chinese children, but only 10% are diagnosed, as diagnosis is hindered by low awareness and lack of culturally adapted, objective tools. Existing continuous performance tests are unimodal…
Clinical Decision Support for Digital Dietary Counseling Under GLP-1 Receptor Agonist Therapy: Convergent Mixed Methods Usability and Treatment Satisfaction Pilot Study of the Personalized Nutrition Advisor
Background: Dietary counseling is an essential complement to the growing use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) to achieve sustainable weight loss. Diverse patient needs, the demand for ongoing support, and limited resources…
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Risk for Autism Across Generations
Autism spectrum disorder (ASD) has a complex inheritance pattern and is more common in males. Etiological models suggest that majority of ASD risk is transmitted through common and rare de-novo genetic variation. It has been hypothesized that rare variation could…
Astrocytic cholesterol jams brain clearance in AD
Nature Neuroscience, Published online: 05 May 2026; doi:10.1038/s41593-026-02310-3Zhang and colleagues identify astrocytic calcium–cholesterol–AQP4 signaling that drives glymphatic dysfunction in early Alzheimer’s disease (AD). Attenuating this signaling restored glymphatic flow, reduced amyloid burden and improved cognition in young 5xFAD mice only…
Molecular mechanism of calcium permeability and magnesium block in NMDA receptors
Nature Neuroscience, Published online: 05 May 2026; doi:10.1038/s41593-026-02283-3Using cryo-electron microscopy and electrophysiology, this study explains the structural basis for Ca2+ permeation and Mg2+ block in NMDA receptors and identifies a surrounding lipid network that may tune Mg2+-dependent voltage sensitivity.
What you need to know about hantavirus (don’t panic)
The latest on the abortion pill, paternal deaths, and more health news from Morning Rounds
STAT+: Cytokinetics drug Myqorzo meets twin efficacy goals in study of genetic heart disease
A Cytokinetics heart disease drug — already approved in one indication — succeeded in another Phase 3 trial, a potential boost for sales.
A blueprint for using AI to strengthen democracy
Every few centuries, changes in how information moves reshape how societies govern themselves. The printing press spread vernacular literacy, helping give rise to the Reformation and, eventually, representative government. The telegraph made it possible to administer vast nations like the…
Opinion: The ‘brain drain’ narrative about health professionals misses half of the story
52 health professionals returned home to 43 countries. Here are the unexpected challenges and opportunities they faced.
Opinion: The cruise ship hantavirus outbreak is a warning sign to the U.S.
Leaving the WHO means the U.S. lacks access to necessary information about infectious disease.
STAT+: Top lawmaker takes aim at doctor lobby, linking AMA’s billing codes to fraud fight
A top Republican is asking if the AMA's codes are helping to fuel health care fraud.
Neural Correlates of Suicidal Behavior in Youth
Conditions: Suicidal Ideation; Suicide Attempt; Suicidal Behavior; Depression / Major Depressive Disorder; Hopelessness; Neurobiological Interventions: Behavioral: CAMS Sponsors: The Cleveland Clinic; MQ Mental Health Research Not yet recruiting
The PREVENT Resilience Study
Conditions: Psychological Trauma Interventions: Device: Transcranial Magnetic Stimulation (TMS); Other: TMS Sham Sponsors: Emory University; National Institute of Mental Health (NIMH) Not yet recruiting
TUBSIS 2.0 – Tobacco Use Behavioral Support and Intervention System
Conditions: Tobacco Use Disorder; Nicotine Dependence; Vaping; Smoking Tobacco Interventions: Behavioral: TUBSIS 2.0 Sponsors: University of Zurich; State Secretariat for Education Research and Innovation, Switzerland Recruiting
The Effectiveness of 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS) and Psychological Problems Among Adolescence
Conditions: 4-STEP-Training Program for Social Media Addiction Interventions: Behavioral: 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS) Sponsors: Government College University Faisalabad Not yet recruiting
PrevED MR. Improving Emotion Dysregulation Through Mixed Reality Based Dialectical Behavioral Therapy in Adolescents and Young Adults at Risk of Developing Eating Disorders.
Conditions: Eating Disorders; Emotion Dysregulation Interventions: Behavioral: PrevED MR Intervention Sponsors: Universitat Internacional de Catalunya; Ministerio de Ciencia e Innovación, Spain Not yet recruiting
Optimization of Late Imagery Rescripting Research Using Generative Artificial Intelligence
Conditions: Generalized Anxiety; Fear of Failure; Rumination Interventions: Behavioral: Imagery Rescripting Intervention Sponsors: University of Social Sciences and Humanities, Warsaw Recruiting
Two-week Intensive Outpatient Trauma Treatment.
Conditions: Posttraumatic Stress Disorder (PTSD) Interventions: Other: Prolonged exposure and EMDR Sponsors: Oslo University Hospital Recruiting
KALM-B: Ketamine-assisted Psychotherapy (KAP) to Lessen Morbidity After Burn Injury
Conditions: PTSD and Trauma-related Symptoms Interventions: Behavioral: Preparatory Session; Drug: Ketamine-assisted Psychotherapy Session #1; Drug: Ketamine-assisted Psychotherapy Session #2; Behavioral: Integration Session Sponsors: Irma Fleming; University of Utah Not yet recruiting
Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression
Conditions: Treatment Resistant Depression (TRD) Interventions: Behavioral: Psychedelic Integration Coaching Sponsors: Massachusetts General Hospital; Fireside Project Recruiting
Group PACBT for Depression
Conditions: Depression - Major Depressive Disorder; Psilocybin; Cognitive Behavioral Therapy Interventions: Drug: Psilocybin (drug); Behavioral: Group Cognitive Behavioral Therapy Sponsors: University of California, Los Angeles Not yet recruiting
Group Retreat Psilocybin Therapy for Healthcare Clinicians With Loss of Meaning in Their Work and Symptoms of Depression
Conditions: Depression; Anxiety Interventions: Drug: Psilocybin Sponsors: University of Washington Not yet recruiting

