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2647 results

Tags: Reality testing and perceptual stability, Schizophrenia spectrum, Substance abuse, Substance use

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Pie Day 2026

Ellie’s Pi Day post: https://mitadmissions.org/blogs/entry/pi-day-2026-food-institute/ How Ellie orchestrated the baking of 30 pies: https://mitadmissions.org/blogs/entry/behind-the-scenes-of-thirty-pies/

Tags: None

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Tags: Medication, Mental health, Social and attachment drive

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EEG-based stroke severity classification using higher-order topological features and graph convolutional networks

IntroductionElectroencephalography (EEG)-based stroke analysis has mainly relied on conventional signal and network descriptors, while higher-order brain network structures remain insufficiently characterized.MethodsWe used persistent homology to extract cycle-based topological features from EEG functional networks, capturing higher-order organization with reduced sensitivity to…

Tags: Cognitive focus and executive control

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New gene-editing approaches for β-hemoglobinopathies

Nature Medicine, Published online: 17 April 2026; doi:10.1038/d41591-026-00021-7Three phase 1/2 trials show that direct editing of HBG1 and HBG2 promoters is a promising disease‑agnostic strategy for treating β‑hemoglobinopathies such as sickle-cell disease and β-thalassemia.

Tags: Clinical trial, Medication

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A roadmap to competitive preclinical packages

Nature Medicine, Published online: 17 April 2026; doi:10.1038/s41591-026-04345-2Should researchers avoid translational research in animals in favor of human or AI models? We argue that this debate should focus not on comparing species but instead on how experimental systems can be…

Tags: Academic research, Medication

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How robots learn: A brief, contemporary history

Roboticists used to dream big but build small. They’d hope to match or exceed the extraordinary complexity of the human body, and then they’d spend their career refining robotic arms for auto plants. Aim for C-3P0; end up with the…

Tags: Charity / nonprofit

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The case for fixing everything

The handsome new book Maintenance: Of Everything, Part One, by the tech industry legend Stewart Brand, promises to be the first in a series offering “a comprehensive overview of the civilizational importance of maintenance.” One of Brand’s several biographers described…

Tags: Academic research, Alternative therapies, Anxiety, Cognitive focus and executive control, Fear and threat response, United States

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Why having “humans in the loop” in an AI war is an illusion

The availability of artificial intelligence for use in warfare is at the center of a legal battle between Anthropic and the Pentagon. This debate has become urgent, with AI playing a bigger role than ever before in the current conflict…

Tags: Academic research, Healthcare provider

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Transcutaneous auricular vagus nerve stimulation to alleviate metformin-associated gastrointestinal adverse events and optimize glycaemic control: a randomized, sham-controlled pilot trial protocol

BackgroundGastrointestinal adverse events (GI AEs) are the main dose-limiting side effects of metformin in type 2 diabetes mellitus (T2DM), reducing adherence and compromising long-term glycaemic control. Current strategies (dose adjustment or combination therapy) seldom address both tolerability and sustained metabolic…

Tags: Appetite and ingestive regulation, Biomarker, Clinical trial, Mood and emotional regulation

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Cerebral blood flow and functional connectivity immediate changes following intradermal acupuncture in major depressive disorder

BackgroundAcupuncture has been increasingly applied as an adjunctive treatment for major depressive disorder (MDD), yet its central neurobiological mechanisms remain insufficiently understood. Cerebral blood flow (CBF) and functional connectivity strength (FCS) provide complementary perspectives on regional metabolic activity and large-scale…

Tags: Academic research, Cognitive focus and executive control, Depression, Medication, Mood and emotional regulation

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Effect of low-intensity focused ultrasound on hippocampus of alcohol addicted mice: a preliminary study

Alcohol addiction is a chronic relapsing brain disorder characterized by significant neurobiological changes, particularly within the hippocampus, which mediates emotional regulation and reward-seeking behavior. Previous studies have shown that alcohol-induced neuronal injury contributes to withdrawal-associated anxiety and persistent alcohol preference.…

Tags: Academic research, Anxiety, Dissociation and identity integration, Mood and emotional regulation, Substance abuse, Substance use

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