News Feed
Secondary School Staff Engagement With a School-Based Physical Activity and Sedentary Behavior Initiative Website: Implementation Trial During National Scale-Up
Background: Online platforms are increasingly used to deliver training and implementation resources for large-scale, school-based physical activity initiatives, and understanding behavioral engagement with these platforms is important because it provides an early indicator of…
News
3069 results
Genomic approaches for understanding the evolution of the human brain
Nature Neuroscience, Published online: 21 April 2026; doi:10.1038/s41593-026-02277-1This Review describes how an approach that starts from genetic changes under selection during human evolution and integrates comparative and functional studies can reveal adaptive phenotypes across different evolutionary timescales.
Constituent-constrained word prediction during language comprehension
Nature Neuroscience, Published online: 21 April 2026; doi:10.1038/s41593-026-02272-6Zou et al. reveal a key difference between human brains and large language models (LLMs). While LLMs are optimized to predict the next word, the human brain modulates prediction efficiency by strategically grouping…
STAT+: Kennedy hints at coming breakthrough device announcement
In this edition of STAT Health Tech: Health secretary hints at possible announcement on how breakthrough medical devices are paid for, and more.
The Download: turning down human noise, and LA’s stunning subway upgrade
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. The noise we make is hurting animals. Can we learn to shut up? As human society…
STAT+: Tortugas Neuroscience launches with hopes to develop drugs for brain disorders, other conditions
Tortugas Neuroscience launched Tuesday with plans to develop drugs licensed from Chinese drugmaker Jiangsu Hansoh and Japanese pharmaceutical Eisai.
STAT+: BioAge says experimental pill aimed at reducing heart risks significantly reduced inflammation
BioAge Labs said its investigational pill for cardiovascular risk prevention significantly reduced inflammation in an early study.
Digging for clues about the North Pole’s past
In the past, even with an icebreaker and during peak melt season, getting to the North Pole wasn’t a sure bet. It took favorable winds to crack the frozen ocean surface, and ships had to fight through ice that had…
Opinion: The U.S. health care system is built around looking backward
A reconstruction layer has fallen on medicine. It asks: Was the original decision justified?
Opinion: What happens when a chief executive loses executive functions?
When a CEO develops acquired executive dysfunction yet remains in their role, the challenges are significant.
Cibisatamab and FAP-4-1BBL in microsatellite-stable colorectal cancer: a phase 1b trial
Nature Medicine, Published online: 20 April 2026; doi:10.1038/s41591-026-04380-zAs presented at the 2026 AACR Annual Meeting: in a phase 1b trial, patients with microsatellite-stable colorectal cancer received a FAP-4-1BB ligand together with the CEA-directed T cell engager cibisatamab; the treatment was…
Ciltacabtagene autoleucel in high-risk smoldering multiple myeloma: the CAR-PRISM phase 2 trial
Nature Medicine, Published online: 20 April 2026; doi:10.1038/s41591-026-04365-yAs presented at the 2026 AACR Annual Meeting, in a phase 2 trial, treatment of patients with high-risk smoldering multiple myeloma with BCMA-targeting CAR T cell therapy ciltacabtagene autoleucel was safe and led…
Microbiome signature of Parkinson’s disease in healthy and genetically at-risk individuals
Nature Medicine, Published online: 20 April 2026; doi:10.1038/s41591-026-04318-5Microbiome analysis suggests that gut microbial changes in Parkinson’s disease evolve progressively from healthy individuals to genetically at-risk individuals to clinically affected patients, with the degree of dysbiosis correlating with disease progression.
STAT+: At AACR, a provocative use of CAR-T, Merck’s new thing and cancer’s geography problem
At AACR, a bold use of CAR-T raises hopes and provocative questions about its use in smoldering multiple myeloma.
STAT+: Former banker brought on to revitalize Pfizer’s strategy departs his post
Andrew Baum, a former Citi analyst, has left his role as Pfizer's executive vice president and chief strategy and innovation officer.
Access to Technology-Mediated Community Mental Health Care Among Low-Socioeconomic Status Consumers With Serious Mental Illness: Qualitative Study
Background: Access to mental health care is critical for the effective management of serious mental illness (SMI), but consumers with low socioeconomic status (SES) have lower rates of service usage and worse retention in care. Digital technologies are often lauded…
Opportunities for Digital Health to Support Early Psychosis Care in Ghana: Qualitative Study Among Patients, Caregivers, and Clinicians
Background: Youth experiencing early psychosis in West Africa often face delays in accessing evidence-based treatment. Digital mental health interventions may offer an acceptable and scalable approach to improve access to early psychosis care in West Africa; however, few data exist…
Popular Online Content as a Treatment-as-Usual Control in Digital Mental Health Intervention Trials: Secondary Analysis of Two Online Randomized Controlled Trials With Repeated Measures
Background: Treatment-as-usual (TAU) conditions are intended to reflect the support typically received in routine treatment settings. For digital mental health interventions (DMHIs) delivered online, TAU conditions should reflect the usual patterns of online help-seeking. The lack of ecologically valid TAU…
STAT+: In early trial, CAR-T results raise hope of preventing multiple myeloma in high-risk patients
A CAR-T trial shows promise in preventing smoldering multiple myeloma from becoming the real thing.
STAT+: Trump order to advance psychedelic treatments generates excitement — and worries
President Trump’s executive order on was largely applauded by advocates. But some also quietly worried the White House’s role risks politicizing their field and undermining its credibility.
Opinion: The contradiction at the heart of Republicans’ embrace of psychedelics
“The research is clear about one thing: Recovery is not primarily a pharmacological event,” write Dimitri Mugianis and Ross Ellenhorn.
News Feed
Secondary School Staff Engagement With a School-Based Physical Activity and Sedentary Behavior Initiative Website: Implementation Trial During National Scale-Up
Background: Online platforms are increasingly used to deliver training and implementation resources for large-scale, school-based physical activity initiatives, and understanding behavioral engagement with these platforms is important because it provides an early indicator of…
News
3069 results
Genomic approaches for understanding the evolution of the human brain
Nature Neuroscience, Published online: 21 April 2026; doi:10.1038/s41593-026-02277-1This Review describes how an approach that starts from genetic changes under selection during human evolution and integrates comparative and functional studies can reveal adaptive phenotypes across different evolutionary timescales.
Constituent-constrained word prediction during language comprehension
Nature Neuroscience, Published online: 21 April 2026; doi:10.1038/s41593-026-02272-6Zou et al. reveal a key difference between human brains and large language models (LLMs). While LLMs are optimized to predict the next word, the human brain modulates prediction efficiency by strategically grouping…
STAT+: Kennedy hints at coming breakthrough device announcement
In this edition of STAT Health Tech: Health secretary hints at possible announcement on how breakthrough medical devices are paid for, and more.
The Download: turning down human noise, and LA’s stunning subway upgrade
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. The noise we make is hurting animals. Can we learn to shut up? As human society…
STAT+: Tortugas Neuroscience launches with hopes to develop drugs for brain disorders, other conditions
Tortugas Neuroscience launched Tuesday with plans to develop drugs licensed from Chinese drugmaker Jiangsu Hansoh and Japanese pharmaceutical Eisai.
STAT+: BioAge says experimental pill aimed at reducing heart risks significantly reduced inflammation
BioAge Labs said its investigational pill for cardiovascular risk prevention significantly reduced inflammation in an early study.
Digging for clues about the North Pole’s past
In the past, even with an icebreaker and during peak melt season, getting to the North Pole wasn’t a sure bet. It took favorable winds to crack the frozen ocean surface, and ships had to fight through ice that had…
Opinion: The U.S. health care system is built around looking backward
A reconstruction layer has fallen on medicine. It asks: Was the original decision justified?
Opinion: What happens when a chief executive loses executive functions?
When a CEO develops acquired executive dysfunction yet remains in their role, the challenges are significant.
Cibisatamab and FAP-4-1BBL in microsatellite-stable colorectal cancer: a phase 1b trial
Nature Medicine, Published online: 20 April 2026; doi:10.1038/s41591-026-04380-zAs presented at the 2026 AACR Annual Meeting: in a phase 1b trial, patients with microsatellite-stable colorectal cancer received a FAP-4-1BB ligand together with the CEA-directed T cell engager cibisatamab; the treatment was…
Ciltacabtagene autoleucel in high-risk smoldering multiple myeloma: the CAR-PRISM phase 2 trial
Nature Medicine, Published online: 20 April 2026; doi:10.1038/s41591-026-04365-yAs presented at the 2026 AACR Annual Meeting, in a phase 2 trial, treatment of patients with high-risk smoldering multiple myeloma with BCMA-targeting CAR T cell therapy ciltacabtagene autoleucel was safe and led…
Microbiome signature of Parkinson’s disease in healthy and genetically at-risk individuals
Nature Medicine, Published online: 20 April 2026; doi:10.1038/s41591-026-04318-5Microbiome analysis suggests that gut microbial changes in Parkinson’s disease evolve progressively from healthy individuals to genetically at-risk individuals to clinically affected patients, with the degree of dysbiosis correlating with disease progression.
STAT+: At AACR, a provocative use of CAR-T, Merck’s new thing and cancer’s geography problem
At AACR, a bold use of CAR-T raises hopes and provocative questions about its use in smoldering multiple myeloma.
STAT+: Former banker brought on to revitalize Pfizer’s strategy departs his post
Andrew Baum, a former Citi analyst, has left his role as Pfizer's executive vice president and chief strategy and innovation officer.
Access to Technology-Mediated Community Mental Health Care Among Low-Socioeconomic Status Consumers With Serious Mental Illness: Qualitative Study
Background: Access to mental health care is critical for the effective management of serious mental illness (SMI), but consumers with low socioeconomic status (SES) have lower rates of service usage and worse retention in care. Digital technologies are often lauded…
Opportunities for Digital Health to Support Early Psychosis Care in Ghana: Qualitative Study Among Patients, Caregivers, and Clinicians
Background: Youth experiencing early psychosis in West Africa often face delays in accessing evidence-based treatment. Digital mental health interventions may offer an acceptable and scalable approach to improve access to early psychosis care in West Africa; however, few data exist…
Popular Online Content as a Treatment-as-Usual Control in Digital Mental Health Intervention Trials: Secondary Analysis of Two Online Randomized Controlled Trials With Repeated Measures
Background: Treatment-as-usual (TAU) conditions are intended to reflect the support typically received in routine treatment settings. For digital mental health interventions (DMHIs) delivered online, TAU conditions should reflect the usual patterns of online help-seeking. The lack of ecologically valid TAU…
STAT+: In early trial, CAR-T results raise hope of preventing multiple myeloma in high-risk patients
A CAR-T trial shows promise in preventing smoldering multiple myeloma from becoming the real thing.
STAT+: Trump order to advance psychedelic treatments generates excitement — and worries
President Trump’s executive order on was largely applauded by advocates. But some also quietly worried the White House’s role risks politicizing their field and undermining its credibility.
Opinion: The contradiction at the heart of Republicans’ embrace of psychedelics
“The research is clear about one thing: Recovery is not primarily a pharmacological event,” write Dimitri Mugianis and Ross Ellenhorn.