News Feed
Secondary School Staff Engagement With a School-Based Physical Activity and Sedentary Behavior Initiative Website: Implementation Trial During National Scale-Up
Background: Online platforms are increasingly used to deliver training and implementation resources for large-scale, school-based physical activity initiatives, and understanding behavioral engagement with these platforms is important because it provides an early indicator of…
News
3069 results
Dr. Jonathan M. Green selected as CEO of the NIH Clinical Center
The NIH Clinical Center is the largest research hospital in the world.
NIH-funded AI model predicts cancer survival from single-cell tumor data
Study links specific cell populations to patient risk in melanoma and liver cancer.
Adapting Behavioral Interventions for Dementia to Address NCDs and Mental Health
Conditions: Mental Health; Non Communicable Diseases; Dementia Interventions: Behavioral: BECOME-D Intervention Sponsors: Possible; University of California, San Francisco; National Institute of Mental Health (NIMH); Ministry of Health and Population, Nepal Completed
MDMA Assisted Therapy for BN
Conditions: Bulimia Nervosa Interventions: Drug: MDMA-AT; Drug: MDMA-AT-BN; Behavioral: Standard Treatment (ST) Sponsors: Icahn School of Medicine at Mount Sinai Not yet recruiting
Pilot Randomized Trial of BA-GSH in VA PC-MHI
Conditions: Depression Interventions: Behavioral: Behavioral Activation-Guided Self-Help Sponsors: VA Office of Research and Development Not yet recruiting
Efficacy and Safety of Sertraline Combined With Lactobacillus Crispatus in Adolescents With Depression : A Multicenter Randomized Controlled Trial
Conditions: Major Depressive Disorder (MDD); Probiotic Intervention Interventions: Combination Product: Sertraline combined with Lactobacillus crispatus; Combination Product: Sertraline combined with placebo Sponsors: First Affiliated Hospital of Chongqing Medical University Not yet recruiting
Transcranial Photobiomodulation (tPBM) for Somatic Symptoms in Treatment-Resistant Depression
Conditions: Treatment-resistant Depression (TRD); Major Depression Disorder Interventions: Device: transcranial photobiomodulation Sponsors: Taipei Veterans General Hospital, Taiwan Recruiting
Photobiomodulation on Core Symptoms of Autism
Conditions: Autism Interventions: Device: Photobiomodulation Sponsors: Suez University Not yet recruiting
Internet addiction among nursing students: application of latent profile analysis and network analysis
BackgroundInternet addiction is widely reported and heterogeneous among nursing students. However, variable-centered approaches may not fully capture profile differences and core symptom patterns, potentially limiting precise interventions. Therefore, identifying distinct profiles and key symptoms is important for informing effective prevention.ObjectiveThis…
Shinya Yamanaka
Dr. Shinya Yamanaka is recognized for the generation of induced pluripotent stem cells (iPSCs) from fibroblasts by a combination of multiple transcription factors, and he won the Nobel Prize in Physiology or Medicine in 2012 jointly with Sir John B.…
Identifying the role of NLRP3 inflammasome in stroke progression and outcome before recanalization
Bellut et al. show that the NLRP3 inflammasome drives hyperacute inflammation and infarct progression during large vessel occlusion in stroke. Pharmacological inhibition reduces infarct growth in mice. NLRP3-positive cells in human pial blood before thrombectomy correlate with clinical outcome and…
Out-of-frame CBX3::ALK fusion drives ALK activation and therapy response
Hang et al. identify an out-of-frame CBX3::ALK fusion in metastatic melanoma that generates functional ALK isoforms through alternative translation start sites. This study demonstrates that rare noncanonical out-of-frame fusions can be oncogenic and therapeutically actionable, highlighting an analytic blind spot…
Combination immunotherapy for colorectal cancer: Clinical applications, rationale, challenges, and future perspectives
Fei et al. review combination immunotherapy strategies for colorectal cancer, focusing on overcoming resistance in pMMR/MSS/MSI-L tumors. They highlight integrating ICIs with chemotherapy, targeted therapy, and radiotherapy and discuss insights into the tumor microenvironment and biomarkers to improve outcomes.
The healthy human global project – Hong Kong: A community-based cross-sectional study of a healthy Asian population
A deeply phenotyped healthy Hong Kong cohort reveals age- and sex-dependent immune, clinical, and lifestyle variation, highlighting population-specific differences and the need to extend systems immunology frameworks beyond European ancestry.
STAT+: With successful trials, Roche takes its MS drug to regulators, but safety questions loom
The Swiss drugmaker Roche presented the latest data for its experimental multiple sclerosis drug, setting the stage for the company to seek approval.
STAT+: From Revolution Medicines, more strong data on KRAS drug and a glimpse of a ‘novel class’ beyond it
A company that is changing the outlook on pancreatic cancer has more promising data for treatments near-term and for a generation beyond.
STAT+: Kyverna Therapeutics plans to submit cell therapy for stiff person syndrome for FDA approval
A one-time cell therapy from Kyverna Therapeutics for stiff person syndrome, a rare disease, improved mobility and reduced disabilities in a late-stage trial.
STAT+: At AACR, more strong results for Revolution Medicine’s KRAS drug, plus assurance from NCI’s director
At AACR, Revolution Medicines presented more eye-catching data about its KRAS-targeting treatment, and Anthony Letai declared the state of cancer research steady.
Roundtables: Unveiling The 10 Things That Matter in AI Right Now
Listen to the session or watch below Watch a special edition of Roundtables simulcast live from EmTech AI, MIT Technology Review’s signature conference for AI leadership. Subscribers got an exclusive first look at a new list capturing 10 key technologies,…
Early life may have breathed oxygen earlier than believed
Around 2.3 billion years ago, a pivotal period known as the Great Oxidation Event set the evolutionary course for oxygen-breathing life on Earth. But MIT geobiologists and colleagues have found evidence that some early forms of life evolved the ability…
News Feed
Secondary School Staff Engagement With a School-Based Physical Activity and Sedentary Behavior Initiative Website: Implementation Trial During National Scale-Up
Background: Online platforms are increasingly used to deliver training and implementation resources for large-scale, school-based physical activity initiatives, and understanding behavioral engagement with these platforms is important because it provides an early indicator of…
News
3069 results
Dr. Jonathan M. Green selected as CEO of the NIH Clinical Center
The NIH Clinical Center is the largest research hospital in the world.
NIH-funded AI model predicts cancer survival from single-cell tumor data
Study links specific cell populations to patient risk in melanoma and liver cancer.
Adapting Behavioral Interventions for Dementia to Address NCDs and Mental Health
Conditions: Mental Health; Non Communicable Diseases; Dementia Interventions: Behavioral: BECOME-D Intervention Sponsors: Possible; University of California, San Francisco; National Institute of Mental Health (NIMH); Ministry of Health and Population, Nepal Completed
MDMA Assisted Therapy for BN
Conditions: Bulimia Nervosa Interventions: Drug: MDMA-AT; Drug: MDMA-AT-BN; Behavioral: Standard Treatment (ST) Sponsors: Icahn School of Medicine at Mount Sinai Not yet recruiting
Pilot Randomized Trial of BA-GSH in VA PC-MHI
Conditions: Depression Interventions: Behavioral: Behavioral Activation-Guided Self-Help Sponsors: VA Office of Research and Development Not yet recruiting
Efficacy and Safety of Sertraline Combined With Lactobacillus Crispatus in Adolescents With Depression : A Multicenter Randomized Controlled Trial
Conditions: Major Depressive Disorder (MDD); Probiotic Intervention Interventions: Combination Product: Sertraline combined with Lactobacillus crispatus; Combination Product: Sertraline combined with placebo Sponsors: First Affiliated Hospital of Chongqing Medical University Not yet recruiting
Transcranial Photobiomodulation (tPBM) for Somatic Symptoms in Treatment-Resistant Depression
Conditions: Treatment-resistant Depression (TRD); Major Depression Disorder Interventions: Device: transcranial photobiomodulation Sponsors: Taipei Veterans General Hospital, Taiwan Recruiting
Photobiomodulation on Core Symptoms of Autism
Conditions: Autism Interventions: Device: Photobiomodulation Sponsors: Suez University Not yet recruiting
Internet addiction among nursing students: application of latent profile analysis and network analysis
BackgroundInternet addiction is widely reported and heterogeneous among nursing students. However, variable-centered approaches may not fully capture profile differences and core symptom patterns, potentially limiting precise interventions. Therefore, identifying distinct profiles and key symptoms is important for informing effective prevention.ObjectiveThis…
Shinya Yamanaka
Dr. Shinya Yamanaka is recognized for the generation of induced pluripotent stem cells (iPSCs) from fibroblasts by a combination of multiple transcription factors, and he won the Nobel Prize in Physiology or Medicine in 2012 jointly with Sir John B.…
Identifying the role of NLRP3 inflammasome in stroke progression and outcome before recanalization
Bellut et al. show that the NLRP3 inflammasome drives hyperacute inflammation and infarct progression during large vessel occlusion in stroke. Pharmacological inhibition reduces infarct growth in mice. NLRP3-positive cells in human pial blood before thrombectomy correlate with clinical outcome and…
Out-of-frame CBX3::ALK fusion drives ALK activation and therapy response
Hang et al. identify an out-of-frame CBX3::ALK fusion in metastatic melanoma that generates functional ALK isoforms through alternative translation start sites. This study demonstrates that rare noncanonical out-of-frame fusions can be oncogenic and therapeutically actionable, highlighting an analytic blind spot…
Combination immunotherapy for colorectal cancer: Clinical applications, rationale, challenges, and future perspectives
Fei et al. review combination immunotherapy strategies for colorectal cancer, focusing on overcoming resistance in pMMR/MSS/MSI-L tumors. They highlight integrating ICIs with chemotherapy, targeted therapy, and radiotherapy and discuss insights into the tumor microenvironment and biomarkers to improve outcomes.
The healthy human global project – Hong Kong: A community-based cross-sectional study of a healthy Asian population
A deeply phenotyped healthy Hong Kong cohort reveals age- and sex-dependent immune, clinical, and lifestyle variation, highlighting population-specific differences and the need to extend systems immunology frameworks beyond European ancestry.
STAT+: With successful trials, Roche takes its MS drug to regulators, but safety questions loom
The Swiss drugmaker Roche presented the latest data for its experimental multiple sclerosis drug, setting the stage for the company to seek approval.
STAT+: From Revolution Medicines, more strong data on KRAS drug and a glimpse of a ‘novel class’ beyond it
A company that is changing the outlook on pancreatic cancer has more promising data for treatments near-term and for a generation beyond.
STAT+: Kyverna Therapeutics plans to submit cell therapy for stiff person syndrome for FDA approval
A one-time cell therapy from Kyverna Therapeutics for stiff person syndrome, a rare disease, improved mobility and reduced disabilities in a late-stage trial.
STAT+: At AACR, more strong results for Revolution Medicine’s KRAS drug, plus assurance from NCI’s director
At AACR, Revolution Medicines presented more eye-catching data about its KRAS-targeting treatment, and Anthony Letai declared the state of cancer research steady.
Roundtables: Unveiling The 10 Things That Matter in AI Right Now
Listen to the session or watch below Watch a special edition of Roundtables simulcast live from EmTech AI, MIT Technology Review’s signature conference for AI leadership. Subscribers got an exclusive first look at a new list capturing 10 key technologies,…
Early life may have breathed oxygen earlier than believed
Around 2.3 billion years ago, a pivotal period known as the Great Oxidation Event set the evolutionary course for oxygen-breathing life on Earth. But MIT geobiologists and colleagues have found evidence that some early forms of life evolved the ability…