News Feed
Constructing the history of a contested region
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
Spawning Season: An Experiment in Queer Parenthood
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
News
3090 results
STAT+: Merck-Kelun lung cancer drug cut risk of tumor progression by 65%, ASCO abstract shows
A type of targeted chemotherapy developed by China-based Kelun-Biotech and licensed to Merck cut the risk of tumor progression by 65% in patients with lung cancer, according to Phase 3…
Conceptualizing Acceptance and Knowledge as Process Variables in Internet-Delivered and Therapist-Supported Cognitive Behavioral Therapy and Acceptance and Commitment Therapy in Primary Care for Insomnia: Pilot Feasibility and Process-Oriented Randomized Controlled Trial
Background: Internet-based interventions for insomnia show promise, but understanding the process variables, such as knowledge acquisition and psychological acceptance, is crucial for enhancing digital adherence and clinical effectiveness. Objective: This study aimed to evaluate the feasibility, adherence, and preliminary clinical…
Roundtables: Can AI Learn to Understand the World?
Listen to the session or watch below AI companies want to build systems that understand the external world and overcome the limitations of LLMs. Recent developments have brought world models to the forefront of the AI discussion. Watch a conversation…
Melatonin for Kids: Is It Safe?
If you’ve spent any time talking to other parents about sleep, you’ve probably heard about melatonin. One person swears by it. Someone else warns against it. And if your child is struggling to fall asleep, it can be hard to…
Scaling creativity in the age of AI
Storytelling is core to humanity’s DNA, stemming from our impulse to express ideals, warnings, hopes, and experiences. Technology has always been woven through the medium and the distribution: from early humans’ innovation of natural pigments and charcoals for cave paintings…
Guarding biotech from China and big bets in longevity
On this week’s episode of “The Readout LOUD,” the hosts discuss STAT's Breakthrough Summit West, where powerful leaders from health care and science rubbed shoulders. They share some of the…
Functional brain alterations associated with acupuncture for chronic pain: a scoping review of fMRI studies
BackgroundChronic pain (CP) is a public health challenge recognized as involving large-scale functional brain dysregulation. Acupuncture is widely used as a non-pharmacological intervention for CP, yet its central mechanisms remain incompletely understood. fMRI provides an approach for investigating acupuncture-related brain…
A compressed sensing neuromorphic processor for sparse signal classification
This paper presents a neuromorphic processing system integrating a compressed sensing spiking neural network (CSSNN) designed for sparse signal classification. The proposed CSSNN combines data coding, data compression, and SNN classification, enabling end-to-end optimization of network performance and model compression.…
Structural connectome analysis using a graph-based deep model for prediction of non-imaging variables
We address the prediction of non-imaging variables based on structural brain connectivity derived from diffusion magnetic resonance images, using graph-based machine learning. We predict age and the mini-mental state examination (MMSE) score as examples of a demographic and a clinical…
Association between frailty and postoperative delirium after transcatheter aortic valve replacement: a meta-analysis
BackgroundPostoperative delirium (POD) is a common complication following transcatheter aortic valve replacement (TAVR) and is associated with adverse outcomes in older patients. Frailty, a multidimensional geriatric syndrome, has been increasingly recognized as a potential risk factor for POD. However, existing…
Associations between serum tumor necrosis factor-alpha, hippocampal-prefrontal-ventricular volumes, and clinical profiles in schizophrenia: a biomarker and neuroimaging study in North Sumatera, Indonesia
IntroductionSchizophrenia is a neurodevelopmental disorder with systemic inflammation that is thought to play a role in its pathophysiology. The pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-α) has been reported to be dysregulated in individuals with schizophrenia, but its relationship with brain…
Baseline working memory was associated with improvement in psychological quality of life in patients with persistent depressive symptoms: a prospective observational study
BackgroundCognitive dysfunction is prevalent in patients with depressive symptoms and contributes to impaired quality of life (QOL) and functional outcomes. However, the prognostic significance of specific cognitive domains for long-term outcomes remains unclear in patients with persistent depressive symptoms.MethodsIn this…
Precision diagnosis model for treatment-resistant depression integrating serum metabolomics and clinical risk factors
ObjectiveThis study aimed to construct a high-efficiency dual-modal diagnostic model for treatment-resistant depression (TRD) by integrating serum metabolomics and clinical risk factors, and explore its metabolic pathological mechanisms.MethodsA total of 93 major depressive disorder (MDD) patients (53 TRD, 40 non-TRD)…
ESMR: a process framework for calibration dynamics across psychosomatic and psychiatric phenomena
The brain can be modeled as a generative system that predicts bodily and environmental input and reduces mismatch through updating and action. From this perspective, stress is treated not as prediction error per se, but as a condition in which…
AI-guided redesign of laboratory-evolved reverse transcriptases enhances prime editing
Nature Biotechnology, Published online: 21 May 2026; doi:10.1038/s41587-026-03149-6A computational redesign strategy improves evolved prime editors.
Integrating public health into house design
Nature Medicine, Published online: 21 May 2026; doi:10.1038/s41591-026-04413-7Housing is not just a backdrop to health, but a powerful intervention. A study now shows that redesigning the home environment can improve child health outcomes, but success requires community co-design and solutions…
Resetting autoimmune disease with CAR cell therapies
Nature Medicine, Published online: 21 May 2026; doi:10.1038/s41591-026-04430-6This Review surveys the fast-developing landscape of CAR T cells in autoimmune disease from both a technological and clinical standpoint, exploring the concept of deep B cell depletion and immune ‘reset’.
News Feed
Constructing the history of a contested region
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
Spawning Season: An Experiment in Queer Parenthood
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
News
3090 results
STAT+: Merck-Kelun lung cancer drug cut risk of tumor progression by 65%, ASCO abstract shows
A type of targeted chemotherapy developed by China-based Kelun-Biotech and licensed to Merck cut the risk of tumor progression by 65% in patients with lung cancer, according to Phase 3…
Conceptualizing Acceptance and Knowledge as Process Variables in Internet-Delivered and Therapist-Supported Cognitive Behavioral Therapy and Acceptance and Commitment Therapy in Primary Care for Insomnia: Pilot Feasibility and Process-Oriented Randomized Controlled Trial
Background: Internet-based interventions for insomnia show promise, but understanding the process variables, such as knowledge acquisition and psychological acceptance, is crucial for enhancing digital adherence and clinical effectiveness. Objective: This study aimed to evaluate the feasibility, adherence, and preliminary clinical…
Roundtables: Can AI Learn to Understand the World?
Listen to the session or watch below AI companies want to build systems that understand the external world and overcome the limitations of LLMs. Recent developments have brought world models to the forefront of the AI discussion. Watch a conversation…
Melatonin for Kids: Is It Safe?
If you’ve spent any time talking to other parents about sleep, you’ve probably heard about melatonin. One person swears by it. Someone else warns against it. And if your child is struggling to fall asleep, it can be hard to…
Scaling creativity in the age of AI
Storytelling is core to humanity’s DNA, stemming from our impulse to express ideals, warnings, hopes, and experiences. Technology has always been woven through the medium and the distribution: from early humans’ innovation of natural pigments and charcoals for cave paintings…
Guarding biotech from China and big bets in longevity
On this week’s episode of “The Readout LOUD,” the hosts discuss STAT's Breakthrough Summit West, where powerful leaders from health care and science rubbed shoulders. They share some of the…
Functional brain alterations associated with acupuncture for chronic pain: a scoping review of fMRI studies
BackgroundChronic pain (CP) is a public health challenge recognized as involving large-scale functional brain dysregulation. Acupuncture is widely used as a non-pharmacological intervention for CP, yet its central mechanisms remain incompletely understood. fMRI provides an approach for investigating acupuncture-related brain…
A compressed sensing neuromorphic processor for sparse signal classification
This paper presents a neuromorphic processing system integrating a compressed sensing spiking neural network (CSSNN) designed for sparse signal classification. The proposed CSSNN combines data coding, data compression, and SNN classification, enabling end-to-end optimization of network performance and model compression.…
Structural connectome analysis using a graph-based deep model for prediction of non-imaging variables
We address the prediction of non-imaging variables based on structural brain connectivity derived from diffusion magnetic resonance images, using graph-based machine learning. We predict age and the mini-mental state examination (MMSE) score as examples of a demographic and a clinical…
Association between frailty and postoperative delirium after transcatheter aortic valve replacement: a meta-analysis
BackgroundPostoperative delirium (POD) is a common complication following transcatheter aortic valve replacement (TAVR) and is associated with adverse outcomes in older patients. Frailty, a multidimensional geriatric syndrome, has been increasingly recognized as a potential risk factor for POD. However, existing…
Associations between serum tumor necrosis factor-alpha, hippocampal-prefrontal-ventricular volumes, and clinical profiles in schizophrenia: a biomarker and neuroimaging study in North Sumatera, Indonesia
IntroductionSchizophrenia is a neurodevelopmental disorder with systemic inflammation that is thought to play a role in its pathophysiology. The pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-α) has been reported to be dysregulated in individuals with schizophrenia, but its relationship with brain…
Baseline working memory was associated with improvement in psychological quality of life in patients with persistent depressive symptoms: a prospective observational study
BackgroundCognitive dysfunction is prevalent in patients with depressive symptoms and contributes to impaired quality of life (QOL) and functional outcomes. However, the prognostic significance of specific cognitive domains for long-term outcomes remains unclear in patients with persistent depressive symptoms.MethodsIn this…
Precision diagnosis model for treatment-resistant depression integrating serum metabolomics and clinical risk factors
ObjectiveThis study aimed to construct a high-efficiency dual-modal diagnostic model for treatment-resistant depression (TRD) by integrating serum metabolomics and clinical risk factors, and explore its metabolic pathological mechanisms.MethodsA total of 93 major depressive disorder (MDD) patients (53 TRD, 40 non-TRD)…
ESMR: a process framework for calibration dynamics across psychosomatic and psychiatric phenomena
The brain can be modeled as a generative system that predicts bodily and environmental input and reduces mismatch through updating and action. From this perspective, stress is treated not as prediction error per se, but as a condition in which…
AI-guided redesign of laboratory-evolved reverse transcriptases enhances prime editing
Nature Biotechnology, Published online: 21 May 2026; doi:10.1038/s41587-026-03149-6A computational redesign strategy improves evolved prime editors.
Integrating public health into house design
Nature Medicine, Published online: 21 May 2026; doi:10.1038/s41591-026-04413-7Housing is not just a backdrop to health, but a powerful intervention. A study now shows that redesigning the home environment can improve child health outcomes, but success requires community co-design and solutions…
Resetting autoimmune disease with CAR cell therapies
Nature Medicine, Published online: 21 May 2026; doi:10.1038/s41591-026-04430-6This Review surveys the fast-developing landscape of CAR T cells in autoimmune disease from both a technological and clinical standpoint, exploring the concept of deep B cell depletion and immune ‘reset’.