News Feed
Pervasive patterns in bird songs resemble those in human speech and song and are independent of vocal learning
Science, Volume 394, Issue 6823, Page 556-561, October 2026.
Constructing the history of a contested region
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
News
3090 results
An AI framework for multi-disease detection via retinal imaging
Nature Medicine, Published online: 20 May 2026; doi:10.1038/s41591-026-04424-4Using large-scale retinal images from community and tertiary hospitals, we developed Reti-Pioneer, a quality-aware, multi-task framework for multi-disease detection. Diverse external validation confirmed its generalizability. Furthermore, a prospective silent trial and clinical pilot…
Unintended consequences of legacy oversight in digital medicine
Nature Medicine, Published online: 20 May 2026; doi:10.1038/s41591-026-04417-3Unintended consequences of legacy oversight in digital medicine
Pathogenic germline variations and cancer risks in pediatric patients referred for genetic testing
Nature Medicine, Published online: 20 May 2026; doi:10.1038/s41591-026-04423-5Analyses of sequencing data from 75,602 children referred for genetic testing from 2016 to 2025 provide insights on the association between pathogenic germline variants and childhood cancer.
Considering biological limitations of lesion network mapping
Nature Neuroscience, Published online: 20 May 2026; doi:10.1038/s41593-026-02319-8Lesion network mapping (LNM), or atrophy network mapping, has become a widely adopted tool for linking focal brain lesions or neurodegenerative brain clusters, respectively, to distributed functional networks associated with cognitive or clinical…
Tau aggregates cause reactivation of transposable DNA elements, leading to Z-RNA–ZBP1-mediated neuronal death
Nature Neuroscience, Published online: 20 May 2026; doi:10.1038/s41593-026-02299-9Tau aggregates disrupt heterochromatin by sequestering H3K9me3, reactivating transposable elements. This generates Z-RNAs, activating ZBP1 to drive neuronal death. ZBP1 haploinsufficiency reverses cognitive decline in aged tau mice, offering a therapeutic target for…
The Download: fully artificial chicken eggs and why Musk lost
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Colossal Biosciences is growing chickens in a 3D-printed artificial eggshell The baby chicks were shifting and…
There’s a leadership vacuum at NIH, too
USAID cuts have painful outcomes for the Ebola outbreak, states sue over a new professional ed loan rule, and other health news
After a critique from Rubio, WHO defends work on Ebola response
The WHO defended its Ebola response, noting it's national authorities who detect outbreaks. Marco Rubio had said the WHO was 'a little late'
STAT+: Senate Democrats propose adding long-term care benefit to Medicare
It's part of Democrats' strategy to focus on health care affordability and access in drawing contrasts with Republicans ahead of the midterms.
STAT+: OpenEvidence makes its pitch to hospitals. ‘We’re not crazy monsters’
OpenEvidence CTO Zachary Ziegler said, at the STAT Breakthrough Summit West, that the company is looking beyond physician users.
STAT+: NIH behind in filling top roles, with 15 of 27 institutes led by acting directors
An NIH leadership vacuum has persisted for months, with 15 of the 27 institutes being led by acting directors.
Sleep Architecture as a Digital Biomarker for Postpartum Depression in Hong Kong Mothers
Conditions: Postpartum Women Sponsors: The University of Hong Kong Not yet recruiting
Binge Eating, Depression and Anxiety Outcomes After Sleeve Gastrectomy Versus Gastric Bypass: A Cohort Study
Conditions: Obesity Interventions: Procedure: Laparoscopic Sleeve Gastrectomy; Procedure: Gastric Bypass Sponsors: Cairo University Recruiting
Colossal Biosciences is growing chickens in a 3D-printed artificial eggshell
The baby chicks were shifting and starting to pip—or trying to hatch. But not from an egg. Instead, these chickens were growing inside transparent 3D-printed plastic cups at the Dallas headquarters of Colossal Biosciences. The biotech company today claimed it…
Machine learning-based predictive factor analysis of depression among Chinese adolescents
IntroductionAdolescent depression has emerged as a critical global public health concern, with rising prevalence in China posing severe threats to psychological development and social adaptation. Traditional statistical methods face limitations in capturing complex non-linear relationships and interactions among influencing factors,…
Understanding the workplace needs of autistic adults in Singapore: insights to inform inclusive AI support
IntroductionAutistic adults face persistent challenges in obtaining and sustaining meaningful employment. Despite growing attention to workplace inclusion, research on autistic adults’ employment experiences in non-Western contexts remains scarce. The potential of emerging technologies, such as large language models (LLMs), to…
T cell-engaging bispecific antibodies for myeloid malignancies: Targets, formats, and clinical challenges
Paczesny et al. review why bispecific antibodies, successful in other blood cancers, have lagged in acute myeloid leukemia. They highlight how limited tumor specificity and toxicity hinder progress and outline emerging targets and engineering strategies that could enable safer, more…
Antibody-drug conjugates in breast cancer: Progress and future directions
Newman et al. review the evolving landscape of antibody-drug conjugates (ADCs) in breast cancer, including approved agents, resistance mechanisms, and combinatorial strategies. The authors highlight novel agents, antigen targets, and next-generation platforms, underscoring the need for predictive biomarkers and optimized…
Microbiome biomarkers in autism spectrum disorder: Toward prediction, diagnosis, and prognosis
Wong et al. review gut microbiota biomarkers for ASD, detailing gut-brain axis mechanisms, biomarker evolution from taxonomic profiling to multi-omics and multi-kingdom integration, key translational challenges, and actionable research guidelines to boost clinical utility for ASD diagnosis and prognosis.
BDNF insufficiency exacerbates ALS progression
Xu and He et al. provide in vivo evidence that BDNF insufficiency exacerbates the symptoms and pathologies in amyotrophic lateral sclerosis (ALS) patients and mouse models, leading to accelerated demise. They develop an agonistic antibody that boosts BDNF signaling and…
News Feed
Pervasive patterns in bird songs resemble those in human speech and song and are independent of vocal learning
Science, Volume 394, Issue 6823, Page 556-561, October 2026.
Constructing the history of a contested region
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
News
3090 results
An AI framework for multi-disease detection via retinal imaging
Nature Medicine, Published online: 20 May 2026; doi:10.1038/s41591-026-04424-4Using large-scale retinal images from community and tertiary hospitals, we developed Reti-Pioneer, a quality-aware, multi-task framework for multi-disease detection. Diverse external validation confirmed its generalizability. Furthermore, a prospective silent trial and clinical pilot…
Unintended consequences of legacy oversight in digital medicine
Nature Medicine, Published online: 20 May 2026; doi:10.1038/s41591-026-04417-3Unintended consequences of legacy oversight in digital medicine
Pathogenic germline variations and cancer risks in pediatric patients referred for genetic testing
Nature Medicine, Published online: 20 May 2026; doi:10.1038/s41591-026-04423-5Analyses of sequencing data from 75,602 children referred for genetic testing from 2016 to 2025 provide insights on the association between pathogenic germline variants and childhood cancer.
Considering biological limitations of lesion network mapping
Nature Neuroscience, Published online: 20 May 2026; doi:10.1038/s41593-026-02319-8Lesion network mapping (LNM), or atrophy network mapping, has become a widely adopted tool for linking focal brain lesions or neurodegenerative brain clusters, respectively, to distributed functional networks associated with cognitive or clinical…
Tau aggregates cause reactivation of transposable DNA elements, leading to Z-RNA–ZBP1-mediated neuronal death
Nature Neuroscience, Published online: 20 May 2026; doi:10.1038/s41593-026-02299-9Tau aggregates disrupt heterochromatin by sequestering H3K9me3, reactivating transposable elements. This generates Z-RNAs, activating ZBP1 to drive neuronal death. ZBP1 haploinsufficiency reverses cognitive decline in aged tau mice, offering a therapeutic target for…
The Download: fully artificial chicken eggs and why Musk lost
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Colossal Biosciences is growing chickens in a 3D-printed artificial eggshell The baby chicks were shifting and…
There’s a leadership vacuum at NIH, too
USAID cuts have painful outcomes for the Ebola outbreak, states sue over a new professional ed loan rule, and other health news
After a critique from Rubio, WHO defends work on Ebola response
The WHO defended its Ebola response, noting it's national authorities who detect outbreaks. Marco Rubio had said the WHO was 'a little late'
STAT+: Senate Democrats propose adding long-term care benefit to Medicare
It's part of Democrats' strategy to focus on health care affordability and access in drawing contrasts with Republicans ahead of the midterms.
STAT+: OpenEvidence makes its pitch to hospitals. ‘We’re not crazy monsters’
OpenEvidence CTO Zachary Ziegler said, at the STAT Breakthrough Summit West, that the company is looking beyond physician users.
STAT+: NIH behind in filling top roles, with 15 of 27 institutes led by acting directors
An NIH leadership vacuum has persisted for months, with 15 of the 27 institutes being led by acting directors.
Sleep Architecture as a Digital Biomarker for Postpartum Depression in Hong Kong Mothers
Conditions: Postpartum Women Sponsors: The University of Hong Kong Not yet recruiting
Binge Eating, Depression and Anxiety Outcomes After Sleeve Gastrectomy Versus Gastric Bypass: A Cohort Study
Conditions: Obesity Interventions: Procedure: Laparoscopic Sleeve Gastrectomy; Procedure: Gastric Bypass Sponsors: Cairo University Recruiting
Colossal Biosciences is growing chickens in a 3D-printed artificial eggshell
The baby chicks were shifting and starting to pip—or trying to hatch. But not from an egg. Instead, these chickens were growing inside transparent 3D-printed plastic cups at the Dallas headquarters of Colossal Biosciences. The biotech company today claimed it…
Machine learning-based predictive factor analysis of depression among Chinese adolescents
IntroductionAdolescent depression has emerged as a critical global public health concern, with rising prevalence in China posing severe threats to psychological development and social adaptation. Traditional statistical methods face limitations in capturing complex non-linear relationships and interactions among influencing factors,…
Understanding the workplace needs of autistic adults in Singapore: insights to inform inclusive AI support
IntroductionAutistic adults face persistent challenges in obtaining and sustaining meaningful employment. Despite growing attention to workplace inclusion, research on autistic adults’ employment experiences in non-Western contexts remains scarce. The potential of emerging technologies, such as large language models (LLMs), to…
T cell-engaging bispecific antibodies for myeloid malignancies: Targets, formats, and clinical challenges
Paczesny et al. review why bispecific antibodies, successful in other blood cancers, have lagged in acute myeloid leukemia. They highlight how limited tumor specificity and toxicity hinder progress and outline emerging targets and engineering strategies that could enable safer, more…
Antibody-drug conjugates in breast cancer: Progress and future directions
Newman et al. review the evolving landscape of antibody-drug conjugates (ADCs) in breast cancer, including approved agents, resistance mechanisms, and combinatorial strategies. The authors highlight novel agents, antigen targets, and next-generation platforms, underscoring the need for predictive biomarkers and optimized…
Microbiome biomarkers in autism spectrum disorder: Toward prediction, diagnosis, and prognosis
Wong et al. review gut microbiota biomarkers for ASD, detailing gut-brain axis mechanisms, biomarker evolution from taxonomic profiling to multi-omics and multi-kingdom integration, key translational challenges, and actionable research guidelines to boost clinical utility for ASD diagnosis and prognosis.
BDNF insufficiency exacerbates ALS progression
Xu and He et al. provide in vivo evidence that BDNF insufficiency exacerbates the symptoms and pathologies in amyotrophic lateral sclerosis (ALS) patients and mouse models, leading to accelerated demise. They develop an agonistic antibody that boosts BDNF signaling and…

