The MHRA is launching a new AI regulatory sandbox to improve medicines safety and accelerate the development of new treatments.
EEG Biomarkers for ADHD Stimulant Treatment
Conditions: ADHD
Interventions: Drug: methylphenidate HCl; Drug: Mixed amphetamine salts extended release
Sponsors: Boston Children’s Hospital; Seattle Children’s Hospital; Tris Pharma, Inc.
Not yet recruiting
Interventions: Drug: methylphenidate HCl; Drug: Mixed amphetamine salts extended release
Sponsors: Boston Children’s Hospital; Seattle Children’s Hospital; Tris Pharma, Inc.
Not yet recruiting
Non-Coding RNA Gene Expression in Psychiatric Disorders
Conditions: Schizophrenia Disorders; Major Depression; Bipolar Affective Disorders; Obsessive Compulsive Disorder (OCD); Anxiety Disorder (Panic Disorder or GAD)
Interventions: Genetic: Real-time Polymerase Chain Reaction
Sponsors: Carmen Concerto
Not yet recruiting
Interventions: Genetic: Real-time Polymerase Chain Reaction
Sponsors: Carmen Concerto
Not yet recruiting
Evaluation of Depression Screening Methods Administered by Registered Nurses in Chronic Hemodialysis Patients
Conditions: Depressive Disorders; End-stage Chronic Kidney Disease Treated With Hemodialysis
Interventions: Other: evaluate the psychometric performance of different modalities of hetero-assessment of depressive symptoms by nurses
Sponsors: Centre Hospitalier Annecy Genevois; GIRCI Auvergne Rhone-Alpes; SFNDT – Société Francophone de Néphrologie, Dialyse et Transplantation
Not yet recruiting
Interventions: Other: evaluate the psychometric performance of different modalities of hetero-assessment of depressive symptoms by nurses
Sponsors: Centre Hospitalier Annecy Genevois; GIRCI Auvergne Rhone-Alpes; SFNDT – Société Francophone de Néphrologie, Dialyse et Transplantation
Not yet recruiting
Using Fenfluramine to Test the Serotonin Deficiency Theory of Depression
Conditions: Depression – Major Depressive Disorder
Interventions: Drug: Fenfluramine Hydrochloride; Radiation: [11C]Cimbi-36; Drug: Placebo
Sponsors: Imperial College Healthcare NHS Trust; University of Oxford
Not yet recruiting
Interventions: Drug: Fenfluramine Hydrochloride; Radiation: [11C]Cimbi-36; Drug: Placebo
Sponsors: Imperial College Healthcare NHS Trust; University of Oxford
Not yet recruiting
Artificial Intelligence Powered Digital Education Based on the Neuman Systems Model for Breast Cancer Patients Receiving Radiotherap
Conditions: Breast Cancer; Radiodermatitis
Interventions: Behavioral: Neuman-Based AI-Supported Digital Education Program; Other: Standard Care (in control arm)
Sponsors: Ataturk University
Not yet recruiting
Interventions: Behavioral: Neuman-Based AI-Supported Digital Education Program; Other: Standard Care (in control arm)
Sponsors: Ataturk University
Not yet recruiting
Two-component Radiology-guided Autonomous Cascade Engine (TRACE)
Conditions: Gastric Cancer (Diagnosis)
Interventions: Diagnostic Test: Utilizing the TRACE model to assist radiologists in T-staging; Other: washout period; Diagnostic Test: Utilizing the TRACE model to assist radiologists in T-staging
Sponsors: Liaoning Cancer Hospital & Institute
Recruiting
Interventions: Diagnostic Test: Utilizing the TRACE model to assist radiologists in T-staging; Other: washout period; Diagnostic Test: Utilizing the TRACE model to assist radiologists in T-staging
Sponsors: Liaoning Cancer Hospital & Institute
Recruiting
AIDE: Decision Support for Anastomosis or Colostomy in Emergency Surgery for Complicated Acute Diverticulitis
Conditions: Complicated Diverticulitis; Acute Diverticulitis; Peritonitis; Perforated Diverticulitis
Interventions: Procedure: Primary anastomosis; Procedure: Hartmann’s procedure
Sponsors: IRCCS San Raffaele Roma
Not yet recruiting
Interventions: Procedure: Primary anastomosis; Procedure: Hartmann’s procedure
Sponsors: IRCCS San Raffaele Roma
Not yet recruiting
The Effectiveness of Dialectical Behavior Therapy on Rumination and Cognitive Avoidance in Teachers
Conditions: Rumination; Cognitive Avoidance
Interventions: Behavioral: Dialectical Behavior Therapy Skills Training
Sponsors: Islamic Azad University, Sanandaj
Completed
Interventions: Behavioral: Dialectical Behavior Therapy Skills Training
Sponsors: Islamic Azad University, Sanandaj
Completed
Comparison of Day Hospitalization Versus Full-Time Hospitalization in the Treatment of Severe Adolescent Obesity
Conditions: Severe Adolescent Obesity; Adolescent Obesity; Pediatric Obesity
Interventions: Other: Day Hospital Multidisciplinary Care; Other: Full-Time Inpatient Multidisciplinary Care
Sponsors: Fondation Santé des Étudiants de France
Not yet recruiting
Interventions: Other: Day Hospital Multidisciplinary Care; Other: Full-Time Inpatient Multidisciplinary Care
Sponsors: Fondation Santé des Étudiants de France
Not yet recruiting