Biophysical modeling of excitation/inhibition balance and conversion to psychosis in the clinical high risk syndrome

Reduced mismatch negativity (MMN) and P300 event-related potential (ERP) components are widely replicated in schizophrenia and are also observed in individuals at clinical high risk for psychosis (CHR-P) who subsequently convert to psychosis. It is unknown whether they reflect changes in excitatory and/or inhibitory synaptic function, both implicated in schizophrenia and considered potential drug targets.

AACR 2026: A Video Update from San Diego

The American Association for Cancer Research (AACR) meeting is off and running in San Diego. Julianna LeMieux, PhD, Deputy Editor in Chief at GEN, and Damian Doherty, Editor in Chief at Inside Precision Medicine, are on the ground—in the talks, expo hall, and press room, covering as much of the news as they can. Here, they take a moment to chat about the first few days at the meeting.

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Regulatory tips from a breakthrough noninvasive device startup

Compremium’s noninvasive Quantis CVP (central venous pressure) measurement device joined the FDA’s Total Product Life Cycle Advisory Program (TAP) after earning Breakthrough Device designation in January 2026. The FDA designed TAP to “help spur more rapid development of high-quality, safe, effective, and innovative medical devices that are critical to public health” and expedite patient access…

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Henry Schein discloses exec pay for longtime CEO Stan Bergman’s final year

Henry Schein reported pay increases for three of its five executives in 2025, while median employee pay increased from the year before. The Melville, New York-based medical product supplier is the 11th-largest medical device company in the world, according to Medical Design & Outsourcing’s 2025 Medtech Big 100 ranking by revenue. Since then, Henry Schein increased…

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CPC Biotech debuts unified bioprocess fluid portfolio

NEWS RELEASE: Introducing CPC Biotech – one brand uniting critical fluid management components New brand unites CPC’s Biopharma connector products with PSG Biotech’s pump, flow meter and sensor expertise – creating an integrated portfolio for the biopharmaceutical industry CPC Biotech to make its public debut at INTERPHEX 2026, April 21–23, Javits Center, New York City Roseville,…

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Freudenberg Medical launches ISO Class 5 cleanroom for biopharma

NEWS RELEASE: Freudenberg Medical launches CleanAssure, an ISO class 5 controlled cleanroom for sterile single-use assemblies New controlled cleaning and sterilization service supports biopharma customers with ready-to-use single-use assemblies Kaiserslautern, Germany — Freudenberg Medical, a global contract design and manufacturing partner to the medical device and biopharma industry, announced the launch of CleanAssure, a new ISO…

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How ZB’s Paragon 28 created a novel curved foot nail system

At Paragon 28, now part of Zimmer Biomet, engineers asked if there was a better implant shape to support foot and ankle anatomy. It took three novel instruments and a novel implant to make it a reality. When Paragon 28 Director of Engineering Ken Roggow and his team approached the drawing board to design a…

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