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3083 results

Teclistamab-based induction treatment in transplant-eligible, newly diagnosed multiple myeloma: a phase 2 trial

Nature Medicine, Published online: 25 June 2026; doi:10.1038/s41591-026-04471-xIn the ongoing phase 2 GMMG-HD10/DSMM-XX (MajesTEC-5) trial in patients with transplant-eligible, newly diagnosed multiple myeloma, induction with the BCMA×CD3 bispecific engager teclistamab in combination with daratumumab plus lenalidomide, with or without bortezomib,…

Tags: Clinical trial, Medication

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Learning shapes neural geometry in the primate prefrontal cortex

Nature Neuroscience, Published online: 25 June 2026; doi:10.1038/s41593-026-02333-wLearning transforms prefrontal cortex activity from flexible, high-dimensional representations into compact, task-relevant and abstract codes, enabling efficient generalization of learned rules to new stimuli and contexts.

Tags: Cognitive focus and executive control

Read more

DBS: from neuromodulation to neuroremodelling

Nature Neuroscience, Published online: 25 June 2026; doi:10.1038/s41593-026-02347-4Deep-brain stimulation (DBS) treats movement and neuropsychiatric disorders through mechanisms that remain unclear. Two studies that combine longitudinal neuroimaging, stimulation experiments and tissue-level analysis show that the effects of DBS evolve in space…

Tags: None

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What Europe’s heat wave means for the power grid

It’s been hard to look away from headlines about the European heat wave this week. Temperatures are breaking records across the continent, and the weather is threatening lives, shutting down schools, and in one particularly ironic case, forcing the cancellation…

Tags: Cognitive focus and executive control, France, United Kingdom

Read more

Social Prescribing for a Mindful Lifestyle

Conditions: Depression and/or Anxiety in the Mild-to-moderate Range; Loneliness; Social Isolation Interventions: Behavioral: Mindfulness Lifestyle Social Prescribing Program Sponsors: Buddhist Tzu Chi General Hospital Not yet recruiting

Tags: Anxiety, Depression, Healthcare provider, Mood and emotional regulation

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The emergence of the web data infrastructure layer for AI

AI is booming. New use cases are emerging each day. To capitalize on the technology’s potential, enterprises require data at scale. In many cases, though, the relevant information is blocked or unstructured, which limits its use by AI models.  To…

Tags: Academic research, Charity / nonprofit, European Union, Social and attachment drive, United States

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Associations between childhood trauma, intolerance of uncertainty, and symptom severity in obsessive-compulsive disorder

BackgroundChildhood trauma (CT) has been associated with obsessive-compulsive disorder (OCD), but its relationship with obsessive-compulsive symptom (OCS) severity remains inconsistent. Intolerance of uncertainty (IU) may represent one of the cognitive processes underlying this association. The present study aimed to examine…

Tags: Academic research, Anxiety, OCD

Read more

Publisher Correction: Oral small molecule GLP-1 receptor agonist aleniglipron in people with overweight or obesity: a randomized, double-blind, placebo-controlled phase 2b trial

Nature Medicine, Published online: 24 June 2026; doi:10.1038/s41591-026-04532-1Publisher Correction: Oral small molecule GLP-1 receptor agonist aleniglipron in people with overweight or obesity: a randomized, double-blind, placebo-controlled phase 2b trial

Tags: Appetite and ingestive regulation, Clinical trial, Medication

Read more

News Feed

News

Disease
Functional Domain
Type
Source
Reset filters

3083 results

Teclistamab-based induction treatment in transplant-eligible, newly diagnosed multiple myeloma: a phase 2 trial

Nature Medicine, Published online: 25 June 2026; doi:10.1038/s41591-026-04471-xIn the ongoing phase 2 GMMG-HD10/DSMM-XX (MajesTEC-5) trial in patients with transplant-eligible, newly diagnosed multiple myeloma, induction with the BCMA×CD3 bispecific engager teclistamab in combination with daratumumab plus lenalidomide, with or without bortezomib,…

Tags: Clinical trial, Medication

Read more

Learning shapes neural geometry in the primate prefrontal cortex

Nature Neuroscience, Published online: 25 June 2026; doi:10.1038/s41593-026-02333-wLearning transforms prefrontal cortex activity from flexible, high-dimensional representations into compact, task-relevant and abstract codes, enabling efficient generalization of learned rules to new stimuli and contexts.

Tags: Cognitive focus and executive control

Read more

DBS: from neuromodulation to neuroremodelling

Nature Neuroscience, Published online: 25 June 2026; doi:10.1038/s41593-026-02347-4Deep-brain stimulation (DBS) treats movement and neuropsychiatric disorders through mechanisms that remain unclear. Two studies that combine longitudinal neuroimaging, stimulation experiments and tissue-level analysis show that the effects of DBS evolve in space…

Tags: None

Read more

What Europe’s heat wave means for the power grid

It’s been hard to look away from headlines about the European heat wave this week. Temperatures are breaking records across the continent, and the weather is threatening lives, shutting down schools, and in one particularly ironic case, forcing the cancellation…

Tags: Cognitive focus and executive control, France, United Kingdom

Read more

Social Prescribing for a Mindful Lifestyle

Conditions: Depression and/or Anxiety in the Mild-to-moderate Range; Loneliness; Social Isolation Interventions: Behavioral: Mindfulness Lifestyle Social Prescribing Program Sponsors: Buddhist Tzu Chi General Hospital Not yet recruiting

Tags: Anxiety, Depression, Healthcare provider, Mood and emotional regulation

Read more

The emergence of the web data infrastructure layer for AI

AI is booming. New use cases are emerging each day. To capitalize on the technology’s potential, enterprises require data at scale. In many cases, though, the relevant information is blocked or unstructured, which limits its use by AI models.  To…

Tags: Academic research, Charity / nonprofit, European Union, Social and attachment drive, United States

Read more

Associations between childhood trauma, intolerance of uncertainty, and symptom severity in obsessive-compulsive disorder

BackgroundChildhood trauma (CT) has been associated with obsessive-compulsive disorder (OCD), but its relationship with obsessive-compulsive symptom (OCS) severity remains inconsistent. Intolerance of uncertainty (IU) may represent one of the cognitive processes underlying this association. The present study aimed to examine…

Tags: Academic research, Anxiety, OCD

Read more

Publisher Correction: Oral small molecule GLP-1 receptor agonist aleniglipron in people with overweight or obesity: a randomized, double-blind, placebo-controlled phase 2b trial

Nature Medicine, Published online: 24 June 2026; doi:10.1038/s41591-026-04532-1Publisher Correction: Oral small molecule GLP-1 receptor agonist aleniglipron in people with overweight or obesity: a randomized, double-blind, placebo-controlled phase 2b trial

Tags: Appetite and ingestive regulation, Clinical trial, Medication

Read more