News Feed
Pervasive patterns in bird songs resemble those in human speech and song and are independent of vocal learning
Science, Volume 394, Issue 6823, Page 556-561, October 2026.
Constructing the history of a contested region
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
News
3083 results
Mapping the spatial landscape of extracellular vesicles in tissues with Spatial-EV-seq
Nature Biotechnology, Published online: 26 June 2026; doi:10.1038/s41587-026-03206-0Spatial-EV-seq is a method for spatially resolved profiling of extracellular vesicles (EVs) in tissues while preserving EVs’ native distribution. By integrating EV mapping with spatial transcriptomics, Spatial-EV-seq enables location-specific analysis of EVs and…
Spatially resolved profiling of extracellular vesicles in tissues with Spatial-EV-seq
Nature Biotechnology, Published online: 26 June 2026; doi:10.1038/s41587-026-03192-3Spatial-EV-seq reveals spatial patterns of extracellular vesicles in tissues.
Adaptive brain stimulation 2.0 for Parkinsonian gait
Nature Medicine, Published online: 26 June 2026; doi:10.1038/s41591-026-04489-1Two studies show that adaptive neuromodulation can improve Parkinsonian gait by matching stimulation to the right circuit at the right moment, pointing toward strategies that decompose complex symptoms into targetable spatial and temporal…
Immersive virtual reality with synchronous neurostimulation for upper-limb recovery after stroke: a randomized feasibility trial
Nature Medicine, Published online: 26 June 2026; doi:10.1038/s41591-026-04486-4A multimodal platform combining immersive virtual reality with a synchronous sensory neurostimulation protocol outperformed conventional rehabilitation in individuals with chronic stroke, driving upper-limb motor gains, restored body representation and improved tactile acuity while…
Re-administration of AAV-mediated gene therapy for OTOF-related deafness: a single-arm trial
Nature Medicine, Published online: 26 June 2026; doi:10.1038/s41591-026-04505-4As part of a clinical trial, re-administration of AAV gene therapy in four patients with congenital deafness, who had previously received a first gene therapy dose and developed neutralizing antibodies, was safe and…
Generative AI-enabled clinical decision support system in primary care: a pragmatic, cluster-randomized trial
Nature Medicine, Published online: 26 June 2026; doi:10.1038/s41591-026-04503-6A pragmatic cluster-randomized trial found that ChatGPT-4o-assisted decision support in Kenyan primary care facilities did not significantly reduce 14-day treatment failure over usual care.
Cliramitug for depletion of cardiac amyloid transthyretin: long-term follow-up of the NI006-101 trial
Nature Medicine, Published online: 26 June 2026; doi:10.1038/s41591-026-04487-3In an open-label extension study of the NI006-101 trial, in which patients with transthyretin amyloidosis cardiomyopathy were treated with the monoclonal antibody cliramitug, which targets misfolded transthyretin, long-term follow-up for a median of…
Mitochondrial stress response drives microglial senescence
Nature Neuroscience, Published online: 26 June 2026; doi:10.1038/s41593-026-02264-6The mitochondrial unfolded protein response (UPRmt) drives microglial senescence and disrupts essential glia–neuron communication. By triggering lipid droplet accumulation and dysregulating the S-adenosylmethionine–polyamine axis, UPRmt fuels the senescence-associated secretory pathway, impairs synaptic pruning…
Interpretable abstractions of artificial neural networks predict behavior and neural activity during human information gathering
Nature Neuroscience, Published online: 26 June 2026; doi:10.1038/s41593-026-02342-9D’Ambrogio et al. combine deep learning and symbolic regression to report an interpretable equation of how humans value information. The equation predicts choices and neural activity in anterior insula, cingulate cortex and midbrain…
Conditioned accumbal dopamine transients forecast individual preference for drug versus natural rewards and compulsive behavior
Nature Neuroscience, Published online: 26 June 2026; doi:10.1038/s41593-026-02331-yPascoli et al. show that nucleus accumbens dopamine transients evoked by reward-predictive cues encode subjective reward value in mice, predicting individual preference for drugs over natural rewards and forecasting vulnerability to compulsive drug-seeking…
The mitochondrial unfolded protein response in human microglia disrupts neuronal–glial communication and promotes senescence
Nature Neuroscience, Published online: 26 June 2026; doi:10.1038/s41593-026-02320-1Mitochondrial proteotoxic stress rewires methionine and lipid metabolism in human microglia, driving cellular senescence and disrupting neuronal–glial communication, revealing a mechanism linking mitochondrial dysfunction to brain aging and neurodegeneration.
Striatal control of amygdalar acetylcholine release during salience-associated processing
Nature Neuroscience, Published online: 26 June 2026; doi:10.1038/s41593-026-02353-6Amygdalar acetylcholine signals dynamically represent salience. Chen et al. show that striatal D1 and D2 neurons oppositely control these signals via basal forebrain cholinergic pathways to shape salience-associated learning.
Supreme Court rules in weedkiller cancer case
Dems want to unmask Eli Lilly's obesity drug user, a new genome-editing tool raises ethics questions, and more health news
Heat waves mess with your brain. Scientists are trying to figure out why.
It’s been hot in London this week. Really hot. A dangerous heat wave has hit Western Europe. Yesterday, the UK recorded its highest ever June temperature at 36.1 °C (about 97 °F). But as the weather app on my phone…
Jails are the frontline in fielding dangerous new type of drug withdrawal
Medetomidine-laced opioids cause severe, life-threatening withdrawal in jails. Here's why many facilities remain ill-equipped to treat a growing crisis.
Opinion: ‘The Hot Zone’ led me to work with Ebola patients. Now I have mixed feelings about the book
“The reality of Ebola is simultaneously less sensational and far more challenging than most people imagine,” writes Krutika Kuppalli.
Opinion: Joseph Fraumeni Jr., pioneering cancer genetics researcher, devoted his life to families like mine
“They don't make many like Joe Fraumeni anymore,” writes Lawrence Ingrassia, author of “A Fatal Inheritance.”
What is pulmonary hypertension and why would a new GLP-1 help?
A report about unusual access to an experimental obesity drug has raised interest in the condition pulmonary hypertension.
A Pilot Study of Adjunctive Structured Supportive Psychotherapy in Schizophrenia
Conditions: Schizophrenia; Cognitive and Executive Dysfunction; Neuroinflammation Interventions: Behavioral: Structured supportive psychotherapy; Drug: Risperidone 2 mg; Behavioral: Standard Clinical Care with Active Control; Drug: Risperidone 2 mg Sponsors: Hasanuddin University Completed
News Feed
Pervasive patterns in bird songs resemble those in human speech and song and are independent of vocal learning
Science, Volume 394, Issue 6823, Page 556-561, October 2026.
Constructing the history of a contested region
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
News
3083 results
Mapping the spatial landscape of extracellular vesicles in tissues with Spatial-EV-seq
Nature Biotechnology, Published online: 26 June 2026; doi:10.1038/s41587-026-03206-0Spatial-EV-seq is a method for spatially resolved profiling of extracellular vesicles (EVs) in tissues while preserving EVs’ native distribution. By integrating EV mapping with spatial transcriptomics, Spatial-EV-seq enables location-specific analysis of EVs and…
Spatially resolved profiling of extracellular vesicles in tissues with Spatial-EV-seq
Nature Biotechnology, Published online: 26 June 2026; doi:10.1038/s41587-026-03192-3Spatial-EV-seq reveals spatial patterns of extracellular vesicles in tissues.
Adaptive brain stimulation 2.0 for Parkinsonian gait
Nature Medicine, Published online: 26 June 2026; doi:10.1038/s41591-026-04489-1Two studies show that adaptive neuromodulation can improve Parkinsonian gait by matching stimulation to the right circuit at the right moment, pointing toward strategies that decompose complex symptoms into targetable spatial and temporal…
Immersive virtual reality with synchronous neurostimulation for upper-limb recovery after stroke: a randomized feasibility trial
Nature Medicine, Published online: 26 June 2026; doi:10.1038/s41591-026-04486-4A multimodal platform combining immersive virtual reality with a synchronous sensory neurostimulation protocol outperformed conventional rehabilitation in individuals with chronic stroke, driving upper-limb motor gains, restored body representation and improved tactile acuity while…
Re-administration of AAV-mediated gene therapy for OTOF-related deafness: a single-arm trial
Nature Medicine, Published online: 26 June 2026; doi:10.1038/s41591-026-04505-4As part of a clinical trial, re-administration of AAV gene therapy in four patients with congenital deafness, who had previously received a first gene therapy dose and developed neutralizing antibodies, was safe and…
Generative AI-enabled clinical decision support system in primary care: a pragmatic, cluster-randomized trial
Nature Medicine, Published online: 26 June 2026; doi:10.1038/s41591-026-04503-6A pragmatic cluster-randomized trial found that ChatGPT-4o-assisted decision support in Kenyan primary care facilities did not significantly reduce 14-day treatment failure over usual care.
Cliramitug for depletion of cardiac amyloid transthyretin: long-term follow-up of the NI006-101 trial
Nature Medicine, Published online: 26 June 2026; doi:10.1038/s41591-026-04487-3In an open-label extension study of the NI006-101 trial, in which patients with transthyretin amyloidosis cardiomyopathy were treated with the monoclonal antibody cliramitug, which targets misfolded transthyretin, long-term follow-up for a median of…
Mitochondrial stress response drives microglial senescence
Nature Neuroscience, Published online: 26 June 2026; doi:10.1038/s41593-026-02264-6The mitochondrial unfolded protein response (UPRmt) drives microglial senescence and disrupts essential glia–neuron communication. By triggering lipid droplet accumulation and dysregulating the S-adenosylmethionine–polyamine axis, UPRmt fuels the senescence-associated secretory pathway, impairs synaptic pruning…
Interpretable abstractions of artificial neural networks predict behavior and neural activity during human information gathering
Nature Neuroscience, Published online: 26 June 2026; doi:10.1038/s41593-026-02342-9D’Ambrogio et al. combine deep learning and symbolic regression to report an interpretable equation of how humans value information. The equation predicts choices and neural activity in anterior insula, cingulate cortex and midbrain…
Conditioned accumbal dopamine transients forecast individual preference for drug versus natural rewards and compulsive behavior
Nature Neuroscience, Published online: 26 June 2026; doi:10.1038/s41593-026-02331-yPascoli et al. show that nucleus accumbens dopamine transients evoked by reward-predictive cues encode subjective reward value in mice, predicting individual preference for drugs over natural rewards and forecasting vulnerability to compulsive drug-seeking…
The mitochondrial unfolded protein response in human microglia disrupts neuronal–glial communication and promotes senescence
Nature Neuroscience, Published online: 26 June 2026; doi:10.1038/s41593-026-02320-1Mitochondrial proteotoxic stress rewires methionine and lipid metabolism in human microglia, driving cellular senescence and disrupting neuronal–glial communication, revealing a mechanism linking mitochondrial dysfunction to brain aging and neurodegeneration.
Striatal control of amygdalar acetylcholine release during salience-associated processing
Nature Neuroscience, Published online: 26 June 2026; doi:10.1038/s41593-026-02353-6Amygdalar acetylcholine signals dynamically represent salience. Chen et al. show that striatal D1 and D2 neurons oppositely control these signals via basal forebrain cholinergic pathways to shape salience-associated learning.
Supreme Court rules in weedkiller cancer case
Dems want to unmask Eli Lilly's obesity drug user, a new genome-editing tool raises ethics questions, and more health news
Heat waves mess with your brain. Scientists are trying to figure out why.
It’s been hot in London this week. Really hot. A dangerous heat wave has hit Western Europe. Yesterday, the UK recorded its highest ever June temperature at 36.1 °C (about 97 °F). But as the weather app on my phone…
Jails are the frontline in fielding dangerous new type of drug withdrawal
Medetomidine-laced opioids cause severe, life-threatening withdrawal in jails. Here's why many facilities remain ill-equipped to treat a growing crisis.
Opinion: ‘The Hot Zone’ led me to work with Ebola patients. Now I have mixed feelings about the book
“The reality of Ebola is simultaneously less sensational and far more challenging than most people imagine,” writes Krutika Kuppalli.
Opinion: Joseph Fraumeni Jr., pioneering cancer genetics researcher, devoted his life to families like mine
“They don't make many like Joe Fraumeni anymore,” writes Lawrence Ingrassia, author of “A Fatal Inheritance.”
What is pulmonary hypertension and why would a new GLP-1 help?
A report about unusual access to an experimental obesity drug has raised interest in the condition pulmonary hypertension.
A Pilot Study of Adjunctive Structured Supportive Psychotherapy in Schizophrenia
Conditions: Schizophrenia; Cognitive and Executive Dysfunction; Neuroinflammation Interventions: Behavioral: Structured supportive psychotherapy; Drug: Risperidone 2 mg; Behavioral: Standard Clinical Care with Active Control; Drug: Risperidone 2 mg Sponsors: Hasanuddin University Completed