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3083 results

Cell atlas of brain aneurysms reveals fibroblast–macrophage crosstalk

Nature Neuroscience, Published online: 24 June 2026; doi:10.1038/s41593-026-02368-zBrain aneurysms are a major cause of stroke worldwide, yet the cellular mechanisms that drive vessel instability remain poorly defined. A combined single-cell and spatial transcriptomic atlas of aneurysm tissue shows previously unrecognized…

Tags: None

Read more

Supporting Student Mental Health With the Safespace Generative AI Chatbot: Mixed Methods Feasibility Study

Background: Generative artificial intelligence (GenAI) chatbots have the potential to provide personalized mental health support to individuals at scale. Objective: This study evaluates the feasibility and usage patterns of the Safespace GenAI chatbot, an artificial intelligence (AI)–driven smartphone app that…

Tags: Academic research, Depression, Mental health, Mood and emotional regulation, Therapy

Read more

Europe’s extreme heat is shutting down power plants

Europe is in the middle of a record-breaking heat wave, and the grid is being pushed to its limits as people turn to fans and air-conditioning to try to stay cool. Some power plants won’t be online to help handle…

Tags: France, United Kingdom

Read more

The Download: introducing the Engineering issue

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Introducing: the Engineering issue We can’t fix everything, but we can be ambitious. We can take…

Tags: Anxiety, Charity / nonprofit, Government / public service, Substance abuse, United States

Read more

Hedgehog signaling enhances the Schwann-like and nerve repair-supportive properties of ectomesenchymal stem cells

IntroductionPeripheral nerve injury (PNI) is characterized by limited regenerative capacity and incomplete functional recovery. Schwann cells (SCs) are essential for nerve repair, but their clinical application is constrained by limited availability. Ectomesenchymal stem cells (EMSCs), derived from neural crest lineage,…

Tags: Academic research, Mood and emotional regulation

Read more

Microglia derived from human induced pluripotent stem cells are regulated by osteopontin, an endogenous extracellular matrix protein maintaining immune homeostasis

IntroductionMicroglia are brain-resident immune cells responsible for maintaining homeostasis, coordinating responses to injury and disease, and mediating regeneration. Upon activation, they undergo dynamic changes in morphology, gene expression, and function, reflecting the nature and context of the stimuli encountered. Although…

Tags: Medication

Read more

Enhancing hematoma expansion prediction in hypertensive intracerebral hemorrhage based on habitat and perihematomal edema radiomics from non-contrast CT: a dual-center study

ObjectivesCharacterizing the microenvironmental habitats within the hematoma may yield crucial imaging biomarkers and improve the early prediction of hematoma expansion (HE) in patients with hypertensive intracerebral hemorrhage (HICH). Our objective was to construct and validate a combined model that integrates…

Tags: Academic research, Biomarker

Read more

Global research landscape, knowledge structure, and emerging trends in adverse childhood experiences and personality disorders: a bibliometric analysis

BackgroundThe relationship between adverse childhood experiences (ACEs) and personality disorders (PDs) has attracted sustained attention in psychiatry, psychology, and public health. Existing studies have mainly examined epidemiological associations, specific PDs diagnoses, or mechanisms, whereas bibliometric evidence mapping the field’s knowledge…

Tags: Academic research, BPD, Cognitive focus and executive control, Depression, Epigenomics, Germany, Mood and emotional regulation, United Kingdom

Read more

Adjunctive berberine for schizophrenia with metabolic syndrome: a systematic review and meta-analysis

BackgroundAntipsychotic-induced metabolic syndrome complicates the clinical management of schizophrenia. This investigation seeks to examine berberine’s efficacy and safety as adjunctive therapy in schizophrenia patients with metabolic syndrome.MethodsA thorough literature search was executed across international (PubMed, Cochrane Library, EMBASE) and Chinese…

Tags: Appetite and ingestive regulation, Schizophrenia spectrum

Read more

Prevalence of depression in patients with advanced cancer receiving palliative care: a meta-analysis of self‐report instruments

BackgroundAlthough the prevalence of depression in patients with advanced cancer receiving palliative care has been widely reported, the estimates vary substantially. This meta-analysis aimed to determine the pooled prevalence of depression in patients with advanced cancer receiving palliative care and…

Tags: Academic research, Depression, Mood and emotional regulation

Read more

Shared reading is associated with fewer emotional/behavioral problems and better prosocial behavior in preschool children: a cross-sectional study in western China

BackgroundThe home literacy environment, particularly shared reading, plays a critical role in preschool children’s cognitive and socioemotional development. However, its associations with emotional and behavioral problems remain underexplored in large-scale studies. This study examined the relationship between shared reading and…

Tags: Academic research, Mental health

Read more

Global trends and neurobiological frontiers of manual therapy in sleep disorders: integrating bibliometrics with clinical evidence

BackgroundSleep disorders not only impair nocturnal rest but also significantly compromise daytime functioning, emotional regulation, and overall mental well-being. Beyond conventional pharmacological treatments, manual therapy has emerged as a promising non-pharmacological intervention. Specifically, emerging evidence suggests its benefits may extend…

Tags: Academic research, Fear and threat response, Medication, Sleep and arousal regulation

Read more

News Feed

News

Disease
Functional Domain
Type
Source
Reset filters

3083 results

Cell atlas of brain aneurysms reveals fibroblast–macrophage crosstalk

Nature Neuroscience, Published online: 24 June 2026; doi:10.1038/s41593-026-02368-zBrain aneurysms are a major cause of stroke worldwide, yet the cellular mechanisms that drive vessel instability remain poorly defined. A combined single-cell and spatial transcriptomic atlas of aneurysm tissue shows previously unrecognized…

Tags: None

Read more

Supporting Student Mental Health With the Safespace Generative AI Chatbot: Mixed Methods Feasibility Study

Background: Generative artificial intelligence (GenAI) chatbots have the potential to provide personalized mental health support to individuals at scale. Objective: This study evaluates the feasibility and usage patterns of the Safespace GenAI chatbot, an artificial intelligence (AI)–driven smartphone app that…

Tags: Academic research, Depression, Mental health, Mood and emotional regulation, Therapy

Read more

Europe’s extreme heat is shutting down power plants

Europe is in the middle of a record-breaking heat wave, and the grid is being pushed to its limits as people turn to fans and air-conditioning to try to stay cool. Some power plants won’t be online to help handle…

Tags: France, United Kingdom

Read more

The Download: introducing the Engineering issue

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Introducing: the Engineering issue We can’t fix everything, but we can be ambitious. We can take…

Tags: Anxiety, Charity / nonprofit, Government / public service, Substance abuse, United States

Read more

Hedgehog signaling enhances the Schwann-like and nerve repair-supportive properties of ectomesenchymal stem cells

IntroductionPeripheral nerve injury (PNI) is characterized by limited regenerative capacity and incomplete functional recovery. Schwann cells (SCs) are essential for nerve repair, but their clinical application is constrained by limited availability. Ectomesenchymal stem cells (EMSCs), derived from neural crest lineage,…

Tags: Academic research, Mood and emotional regulation

Read more

Microglia derived from human induced pluripotent stem cells are regulated by osteopontin, an endogenous extracellular matrix protein maintaining immune homeostasis

IntroductionMicroglia are brain-resident immune cells responsible for maintaining homeostasis, coordinating responses to injury and disease, and mediating regeneration. Upon activation, they undergo dynamic changes in morphology, gene expression, and function, reflecting the nature and context of the stimuli encountered. Although…

Tags: Medication

Read more

Enhancing hematoma expansion prediction in hypertensive intracerebral hemorrhage based on habitat and perihematomal edema radiomics from non-contrast CT: a dual-center study

ObjectivesCharacterizing the microenvironmental habitats within the hematoma may yield crucial imaging biomarkers and improve the early prediction of hematoma expansion (HE) in patients with hypertensive intracerebral hemorrhage (HICH). Our objective was to construct and validate a combined model that integrates…

Tags: Academic research, Biomarker

Read more

Global research landscape, knowledge structure, and emerging trends in adverse childhood experiences and personality disorders: a bibliometric analysis

BackgroundThe relationship between adverse childhood experiences (ACEs) and personality disorders (PDs) has attracted sustained attention in psychiatry, psychology, and public health. Existing studies have mainly examined epidemiological associations, specific PDs diagnoses, or mechanisms, whereas bibliometric evidence mapping the field’s knowledge…

Tags: Academic research, BPD, Cognitive focus and executive control, Depression, Epigenomics, Germany, Mood and emotional regulation, United Kingdom

Read more

Adjunctive berberine for schizophrenia with metabolic syndrome: a systematic review and meta-analysis

BackgroundAntipsychotic-induced metabolic syndrome complicates the clinical management of schizophrenia. This investigation seeks to examine berberine’s efficacy and safety as adjunctive therapy in schizophrenia patients with metabolic syndrome.MethodsA thorough literature search was executed across international (PubMed, Cochrane Library, EMBASE) and Chinese…

Tags: Appetite and ingestive regulation, Schizophrenia spectrum

Read more

Prevalence of depression in patients with advanced cancer receiving palliative care: a meta-analysis of self‐report instruments

BackgroundAlthough the prevalence of depression in patients with advanced cancer receiving palliative care has been widely reported, the estimates vary substantially. This meta-analysis aimed to determine the pooled prevalence of depression in patients with advanced cancer receiving palliative care and…

Tags: Academic research, Depression, Mood and emotional regulation

Read more

Shared reading is associated with fewer emotional/behavioral problems and better prosocial behavior in preschool children: a cross-sectional study in western China

BackgroundThe home literacy environment, particularly shared reading, plays a critical role in preschool children’s cognitive and socioemotional development. However, its associations with emotional and behavioral problems remain underexplored in large-scale studies. This study examined the relationship between shared reading and…

Tags: Academic research, Mental health

Read more

Global trends and neurobiological frontiers of manual therapy in sleep disorders: integrating bibliometrics with clinical evidence

BackgroundSleep disorders not only impair nocturnal rest but also significantly compromise daytime functioning, emotional regulation, and overall mental well-being. Beyond conventional pharmacological treatments, manual therapy has emerged as a promising non-pharmacological intervention. Specifically, emerging evidence suggests its benefits may extend…

Tags: Academic research, Fear and threat response, Medication, Sleep and arousal regulation

Read more