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Diagnostic Discrimination of BOKE STARS, a Bimodal Continuous Performance Test, for Attention-Deficit/Hyperactivity Disorder Assessment in Chinese Children: Single-Center Case-Control Study
Background: Attention-deficit/hyperactivity disorder (ADHD) affects 6.3% of Chinese children, but only 10% are diagnosed, as diagnosis is hindered by low awareness and lack of culturally adapted, objective tools. Existing continuous performance tests are unimodal…
Clinical Decision Support for Digital Dietary Counseling Under GLP-1 Receptor Agonist Therapy: Convergent Mixed Methods Usability and Treatment Satisfaction Pilot Study of the Personalized Nutrition Advisor
Background: Dietary counseling is an essential complement to the growing use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) to achieve sustainable weight loss. Diverse patient needs, the demand for ongoing support, and limited resources…
Medtech CDMO Aptyx names new CEO
Aptyx has promoted CFO David Price to the role of CEO effective immediately, succeeding former Aptyx CEO Gregg Tobin. Price joined the Tempe, Arizona-based medical device contract development and manufacturing organization as CFO in…
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Opinion: The psychedelic revolution is leaving behind people of color
Psychedelics’ potential as a form of treatment is virtually unmatched. But their promise faces both scientific uncertainty and thorny political questions.
Electrophysiological Biomarkers and Treatment Response to Accelerated Transcranial Magnetic Stimulation in Patients With Obsessive-Compulsive Disorder
Conditions: Obsessive - Compulsive Disorder; Transcranial Magnetic Stimilation; Intermittent Theta Burst Stimulation; EEG Interventions: Device: iTBS TMS Sponsors: Istanbul University - Cerrahpasa Recruiting
Predictive Value of Early Peritraumatic Distress Screening for Childbirth-PTSD Following Unplanned Cesarean Delivery
Conditions: Post Traumatic Stress Disorder; Post Partum Depression; Acute Stress Symptoms Interventions: Other: Postpartum Psychological Screening Sponsors: University of British Columbia; Women's Health Research Institute of British Columbia Not yet recruiting
PB-18 Probiotic for Mild to Moderate Depression
Conditions: Depressive Disorder Interventions: Dietary Supplement: Bifidobacterium; Other: Placebo Sponsors: First Affiliated Hospital of Zhejiang University Not yet recruiting
Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression
Conditions: Major Depression Interventions: Drug: D-Cycloserine (DCS); Device: Continuous theta-burst stimulation (cTBS); Device: Transcranial Magnetic Stimulation Sham; Drug: Memantine; Drug: Lorazepam (drug); Drug: Baclofen; Drug: Placebo Sponsors: Mclean Hospital; National Institute of Mental Health (NIMH) Recruiting
STAT+: OxyContin maker Purdue Pharma set to dissolve after judge approves its criminal sentence
At the hearing, the judge heard from mothers who lost sons to overdose, a teenager born into withdrawal, and people who spent years dealing with addiction treatment.
Disneyland’s factory-inspired future
Science, Volume 392, Issue 6797, Page 471-471, April 2026.
Disordered protein LAT encodes relative levels of signaling pathways in T cell activation
Science, Volume 392, Issue 6797, April 2026.
Lymphoid tissue chemokines limit priming duration to preserve CD8+ T cell functionality
Science, Volume 392, Issue 6797, April 2026.
Anticipating the future in an algorithmic age
Science, Volume 392, Issue 6797, Page 472-472, April 2026.
Current Landscape of Mental Health Conversational Agents From a Trauma-Informed Care Lens: Scoping Review
Background: Conversational agents (CAs) are increasingly used in mental health care to enhance access and engagement. However, their safe, ethical, and user-sensitive design remains a challenge. Despite growing attention to trauma-informed approaches in human-computer interaction, there is limited work on…
Remembering J. Craig Venter: a relentless scientist who changed biotech — and was all too easily misunderstood
J. Craig Venter, the scientist whose relentless ambition helped turn genetics from an artisanal trade into an industrialized information machine, died at 79.
STAT+: Katherine Szarama named acting director of FDA’s vaccines and biologics center
Katherine Szarama, who joined the FDA last year to serve as Vinay Prasad’s deputy, will now fill his shoes at CBER.
STAT+: In her own words: Surgeon general nominee Nicole Saphier expresses enthusiasm and caution for MAHA
Examining the past statements and writings of Trump's third surgeon general nominee, Dr. Nicole Saphier, on vaccines, autism, peptides, diet and more.
STAT+: Hair-raising trial results, and Servier’s M&A wishlist
Why are investors excited about hair loss drugs? Will AI make clinical trials run more smoothly? And more in "The Readout LOUD," STAT's weekly biotech podcast.
Exclusive eBook: Inside the stealthy startup that pitched brainless human clones
The ultimate plan to live forever is a brand new body. This subscriber-only eBook explores R3 Bio, a small startup that has pitched a startling and ethically charged vision for “brainless clones” to serve the role of backup human bodies.…
STAT+: As artificial intelligence shows off diagnostic chops, scientists reckon with the way forward
On Thursday, researchers published in Science the results of a study that tested an OpenAI model on diagnostic and clinical reasoning tasks.
This startup’s new mechanistic interpretability tool lets you debug LLMs
The San Francisco–based startup Goodfire just released a new tool, called Silico, that lets researchers and engineers peer inside an AI model and adjust its parameters—the settings that determine a model’s behavior—during training. This could give model makers more fine-grained…

