News Feed
Pervasive patterns in bird songs resemble those in human speech and song and are independent of vocal learning
Science, Volume 394, Issue 6823, Page 556-561, October 2026.
Constructing the history of a contested region
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
News
3083 results
Direct modulation of human GABA-A α1β2γ2 receptors by the endocannabinoid 2-arachidonoylglycerol: implications for cannabinoid-related ligands and limitations for anxiolytic drug development
Anxiety disorders are associated with impaired inhibitory neurotransmission mediated by γ-aminobutyric acid type A (GABA-A) receptors. Although benzodiazepines remain effective anxiolytics, their clinical utility is limited by sedation, cognitive impairment, tolerance, and dependence, prompting the search for mechanistically distinct GABAergic…
Federated training of spiking neural networks on edge hardware for audio processing
Spiking Neural Networks have caught significant attention recently for their potential for energy-efficient computation on neuromorphic hardware and their event-driven processing. Spiking Neural networks employ spike-based learning paradigms, which require specialized training procedures such as Surrogate Gradient Descent. At the…
Assessing directional connections between symptoms, cognition, insight, and real-life functioning in schizophrenia: a partial ancestor graphs analysis
IntroductionSchizophrenia is a severe chronic mental disorder causing significant global disability. Understanding the intricate relationships between symptoms, cognitive functions, and real-life outcomes is essential for developing effective interventions. Prior research, while informative, could not often determine the direction of the…
Romanian male patients with the dual diagnosis of schizophrenia and alcohol use disorder: a prospective study of clinical, social, and treatment-related factors affecting quality of life
BackgroundSchizophrenia frequently co-occurs with alcohol use disorder (AUD), resulting in a complex clinical profile associated with poor functional outcomes and reduced quality of life (QoL). Although both conditions independently impair psychosocial functioning, few studies have examined the combined effects of…
Internalizing and externalizing pathways to internet gaming disorder: the roles of anger and social anxiety
BackgroundInternet Gaming Disorder (IGD) represents a significant behavioral health concern, yet the roles of internalizing and externalizing psychological vulnerabilities in its development remain underexplored, particularly in Arabic-speaking populations.ObjectiveThis study examined anger and social anxiety as distinct externalizing and internalizing predictors…
Perception of social support and psychological well-being among mothers of individuals with intellectual disabilities: the mediating role of self-efficacy
BackgroundThe aim of this study is to examine the mediating role of self-efficacy in the relationship between social support perception and psychological well-being among mothers of individuals with intellectual disabilities.MethodsA correlational survey model was used in this study in line…
From cats to cortex: T. gondii and psychosis, depression, and anxiety
This review examines whether cat ownership, via exposure to the neurotropic parasite T. gondii, contributes to vulnerability for psychotic, depressive, and anxiety symptoms. T. gondii establishes lifelong latent infection in the brain and muscle, where it can modulate dopaminergic signaling,…
Deep peptide recognition profiling decodes TCR specificity and enables disease-associated antigen discovery
Nature Biotechnology, Published online: 13 May 2026; doi:10.1038/s41587-026-03128-xA deep-learning method predicts T cell receptor specificity and disease-associated antigens.
Immune-remodeling mRNAs expressing IRF8 or NIK generate durable antitumor immunity in multiple cancer models
Nature Biotechnology, Published online: 13 May 2026; doi:10.1038/s41587-026-03115-2Immune-remodeling mRNAs delivered in lipid nanoparticles boost antitumor immunity.
Fluctuating internal states mediate neural–behavioral covariations in V1
Nature Neuroscience, Published online: 13 May 2026; doi:10.1038/s41593-026-02296-yThe authors report surprising covariations between subthreshold activity of single V1 neurons and behavior, demonstrating that interactions between external sensory inputs and internal states are implemented by a nonlinear modulatory signal in V1.
Closed-loop stimulation modulates attention shifting in children
Nature Neuroscience, Published online: 13 May 2026; doi:10.1038/s41593-026-02294-0Intracranial recordings in children revealed neural signals predicting attentional lapses. Closed-loop stimulation rescued performance and scalp EEG enabled noninvasive modulation, identifying a reproducible marker of attentional control.
Extreme heat is worsening faster for Black Americans
Bill Cassidy's can't-win conundrum, what RFK Jr. gets right and wrong about antidepressants, and more health news
STAT+: Drug meant to make gene therapy safer may also make it less effective
Encoded Therapeutics gives a heads-up to other gene therapy company about the trade-offs with a drug meant to improve safety.
STAT+: Scientists link boy’s tumor to gene therapy viruses, in rare finding
Doctors have linked a boy's tumor to a gene therapy, but say the rare risks need to be weighed against the profound benefits such medicines can offer.
A plan to make drugs in orbit is going commercial
Varda Space Industries, a startup that’s been pitching its ability to perform drug experiments in space, says it has signed up the pharmaceutical company United Therapeutics in what may be remembered as a notable step toward in-orbit manufacturing. The idea…
Opinion: What can ‘blue zones’ really teach us about aging?
Have you heard about blue zones where people tend to live much longer? They’re more complicated than they might sound.
Opinion: RFK Jr.’s antidepressant deprescribing push gets one thing right — and others dangerously wrong
“Deprescribing requires gradual tapering, psychological support, careful risk stratification, and accessible alternatives — none of which Kennedy’s initiative provides at scale.”
A Randomized, Double-blind, Placebo-controlled, Dose-escalating Phase I Clinical Trial
Conditions: Schizophrenia Interventions: Drug: KR23248; Drug: Matching Placebo Sponsors: Jiangxi Kvvit Pharmaceutical Co., Ltd. Not yet recruiting
NIH-funded study maps human pancreatic islet cells, offering new clues to diabetes risk
Comprehensive characterization of islet cells facilitated by national organ donation program.
News Feed
Pervasive patterns in bird songs resemble those in human speech and song and are independent of vocal learning
Science, Volume 394, Issue 6823, Page 556-561, October 2026.
Constructing the history of a contested region
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
News
3083 results
Direct modulation of human GABA-A α1β2γ2 receptors by the endocannabinoid 2-arachidonoylglycerol: implications for cannabinoid-related ligands and limitations for anxiolytic drug development
Anxiety disorders are associated with impaired inhibitory neurotransmission mediated by γ-aminobutyric acid type A (GABA-A) receptors. Although benzodiazepines remain effective anxiolytics, their clinical utility is limited by sedation, cognitive impairment, tolerance, and dependence, prompting the search for mechanistically distinct GABAergic…
Federated training of spiking neural networks on edge hardware for audio processing
Spiking Neural Networks have caught significant attention recently for their potential for energy-efficient computation on neuromorphic hardware and their event-driven processing. Spiking Neural networks employ spike-based learning paradigms, which require specialized training procedures such as Surrogate Gradient Descent. At the…
Assessing directional connections between symptoms, cognition, insight, and real-life functioning in schizophrenia: a partial ancestor graphs analysis
IntroductionSchizophrenia is a severe chronic mental disorder causing significant global disability. Understanding the intricate relationships between symptoms, cognitive functions, and real-life outcomes is essential for developing effective interventions. Prior research, while informative, could not often determine the direction of the…
Romanian male patients with the dual diagnosis of schizophrenia and alcohol use disorder: a prospective study of clinical, social, and treatment-related factors affecting quality of life
BackgroundSchizophrenia frequently co-occurs with alcohol use disorder (AUD), resulting in a complex clinical profile associated with poor functional outcomes and reduced quality of life (QoL). Although both conditions independently impair psychosocial functioning, few studies have examined the combined effects of…
Internalizing and externalizing pathways to internet gaming disorder: the roles of anger and social anxiety
BackgroundInternet Gaming Disorder (IGD) represents a significant behavioral health concern, yet the roles of internalizing and externalizing psychological vulnerabilities in its development remain underexplored, particularly in Arabic-speaking populations.ObjectiveThis study examined anger and social anxiety as distinct externalizing and internalizing predictors…
Perception of social support and psychological well-being among mothers of individuals with intellectual disabilities: the mediating role of self-efficacy
BackgroundThe aim of this study is to examine the mediating role of self-efficacy in the relationship between social support perception and psychological well-being among mothers of individuals with intellectual disabilities.MethodsA correlational survey model was used in this study in line…
From cats to cortex: T. gondii and psychosis, depression, and anxiety
This review examines whether cat ownership, via exposure to the neurotropic parasite T. gondii, contributes to vulnerability for psychotic, depressive, and anxiety symptoms. T. gondii establishes lifelong latent infection in the brain and muscle, where it can modulate dopaminergic signaling,…
Deep peptide recognition profiling decodes TCR specificity and enables disease-associated antigen discovery
Nature Biotechnology, Published online: 13 May 2026; doi:10.1038/s41587-026-03128-xA deep-learning method predicts T cell receptor specificity and disease-associated antigens.
Immune-remodeling mRNAs expressing IRF8 or NIK generate durable antitumor immunity in multiple cancer models
Nature Biotechnology, Published online: 13 May 2026; doi:10.1038/s41587-026-03115-2Immune-remodeling mRNAs delivered in lipid nanoparticles boost antitumor immunity.
Fluctuating internal states mediate neural–behavioral covariations in V1
Nature Neuroscience, Published online: 13 May 2026; doi:10.1038/s41593-026-02296-yThe authors report surprising covariations between subthreshold activity of single V1 neurons and behavior, demonstrating that interactions between external sensory inputs and internal states are implemented by a nonlinear modulatory signal in V1.
Closed-loop stimulation modulates attention shifting in children
Nature Neuroscience, Published online: 13 May 2026; doi:10.1038/s41593-026-02294-0Intracranial recordings in children revealed neural signals predicting attentional lapses. Closed-loop stimulation rescued performance and scalp EEG enabled noninvasive modulation, identifying a reproducible marker of attentional control.
Extreme heat is worsening faster for Black Americans
Bill Cassidy's can't-win conundrum, what RFK Jr. gets right and wrong about antidepressants, and more health news
STAT+: Drug meant to make gene therapy safer may also make it less effective
Encoded Therapeutics gives a heads-up to other gene therapy company about the trade-offs with a drug meant to improve safety.
STAT+: Scientists link boy’s tumor to gene therapy viruses, in rare finding
Doctors have linked a boy's tumor to a gene therapy, but say the rare risks need to be weighed against the profound benefits such medicines can offer.
A plan to make drugs in orbit is going commercial
Varda Space Industries, a startup that’s been pitching its ability to perform drug experiments in space, says it has signed up the pharmaceutical company United Therapeutics in what may be remembered as a notable step toward in-orbit manufacturing. The idea…
Opinion: What can ‘blue zones’ really teach us about aging?
Have you heard about blue zones where people tend to live much longer? They’re more complicated than they might sound.
Opinion: RFK Jr.’s antidepressant deprescribing push gets one thing right — and others dangerously wrong
“Deprescribing requires gradual tapering, psychological support, careful risk stratification, and accessible alternatives — none of which Kennedy’s initiative provides at scale.”
A Randomized, Double-blind, Placebo-controlled, Dose-escalating Phase I Clinical Trial
Conditions: Schizophrenia Interventions: Drug: KR23248; Drug: Matching Placebo Sponsors: Jiangxi Kvvit Pharmaceutical Co., Ltd. Not yet recruiting
NIH-funded study maps human pancreatic islet cells, offering new clues to diabetes risk
Comprehensive characterization of islet cells facilitated by national organ donation program.