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3083 results

Revolution’s aftermath: population based cross-sectional study to understand the intergeneration mental health and wellbeing following the 2024 student-led uprising

BackgroundBangladesh was confronted with a nationwide student uprising in July 2024, that exposed both participants and observers to widespread unrest and traumatic events. To better understand the kind of support the population will need, it is important to understand its…

Tags: Academic research, Mental health, PTSD

Read more

Comparative efficacy of non-pharmacological therapies in adolescents with subthreshold depression: a systematic review and network meta-analysis

BackgroundSubthreshold depression (SD) is highly prevalent in adolescents and young adults aged 11–25 years, leading to impaired psychosocial functioning and a high risk of progression to major depressive disorder (MDD). Non-pharmacological therapies are the mainstay of intervention for adolescent SD,…

Tags: Academic research, Depression, Medication, Mood and emotional regulation

Read more

RESCUE- expected usefulness and willingness to participate in a trauma-informed group intervention for coping with traumatic work experiences in the emergency medical services

Emergency Medical Services personnel (EMS) are confronted with potentially highly stressful and traumatic occupational experiences, placing them at high-risk for mental disorders. Avoidant coping mechanisms, internalized and occupational stigma not only impede disclosure of and processing the incident-related stress but…

Tags: Academic research, Germany, Mental health, Therapy

Read more

Harnessing the power of biomarkers for diffuse intrinsic pontine gliomas

Nature Medicine, Published online: 12 May 2026; doi:10.1038/s41591-026-04399-2The BIOMEDE trial, although negative for its primary endpoint, illustrates the utility of adaptive trial designs and biopsy-informed tumor profiling in guiding treatment decisions and patient counseling — and provides mechanistic evidence that…

Tags: Biomarker, Medication

Read more

Brazil’s big bet on mosquitos

Nature Medicine, Published online: 12 May 2026; doi:10.1038/s41591-026-04388-5As Brazil takes its modified mosquito program from pilot to practice at national scale, what will it take to beat dengue?

Tags: Medication

Read more

Genomic epidemiology of the 2025 mpox epidemic in Sierra Leone

Nature Medicine, Published online: 12 May 2026; doi:10.1038/s41591-026-04385-8A phylogenetic analysis examined the origins of the first mpox outbreak in Sierra Leone and found evidence of an emerging lineage (G.1) that has likely descended from the Nigerian epidemic and emerged in…

Tags: Genomics, Medication

Read more

Data-Driven Decision Support in Obesity Management Commission: enabling more equitable and personalized obesity care

Nature Medicine, Published online: 12 May 2026; doi:10.1038/s41591-026-04363-0Announced in this Comment and in collaboration with Nature Medicine is the convening of the Data-Driven Decision Support in Obesity Management Commission, to promote adequate scientific evidence to support obesity management across global…

Tags: Appetite and ingestive regulation, Medication

Read more

CRISPR−Cas9 CD33-deleted allogeneic hematopoietic cell transplantation with gemtuzumab ozogamicin maintenance in AML: a phase 1/2 trial

Nature Medicine, Published online: 12 May 2026; doi:10.1038/s41591-026-04362-1In a first-in-human trial combining the transplantation of CD33-negative CRISPR-edited hematopoietic cells with the CD33-targeted antibody–drug conjugate gemtuzumab ozogamicin, all transplanted patients achieved primary engraftment, and the treatment was well tolerated.

Tags: Clinical trial, Medication

Read more

Optics-free spatial genomics for mapping mammalian brain aging by IRISeq

Nature Neuroscience, Published online: 12 May 2026; doi:10.1038/s41593-026-02293-1The authors developed an optics-free spatial genomics method to map mouse brain aging, revealing region-specific inflammation and showing that lymphocytes promote harmful interferon signaling, whereas their loss preserves ependymal cells and reshapes glial…

Tags: Genomics

Read more

The Download: a Nobel winner on AI, and the case for fixing everything

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Three things in AI to watch, according to a Nobel-winning economist A few months before he…

Tags: Cognitive focus and executive control, Government / public service, Substance abuse, Substance use, United States

Read more

Case Report: Recurrent pathogenic mutation c.110G>A in DHDDS gene

Recent studies have demonstrated the close association of mutations in the dehydrodolichyl diphosphate synthase (DHDDS) gene with neurodevelopmental disorders and the onset of epilepsy. This report describes a female patient harboring a de novo heterozygous variant c.110G>A (p.Arg37His) in the…

Tags: Academic research, Mental health

Read more

News Feed

News

Disease
Functional Domain
Type
Source
Reset filters

3083 results

Revolution’s aftermath: population based cross-sectional study to understand the intergeneration mental health and wellbeing following the 2024 student-led uprising

BackgroundBangladesh was confronted with a nationwide student uprising in July 2024, that exposed both participants and observers to widespread unrest and traumatic events. To better understand the kind of support the population will need, it is important to understand its…

Tags: Academic research, Mental health, PTSD

Read more

Comparative efficacy of non-pharmacological therapies in adolescents with subthreshold depression: a systematic review and network meta-analysis

BackgroundSubthreshold depression (SD) is highly prevalent in adolescents and young adults aged 11–25 years, leading to impaired psychosocial functioning and a high risk of progression to major depressive disorder (MDD). Non-pharmacological therapies are the mainstay of intervention for adolescent SD,…

Tags: Academic research, Depression, Medication, Mood and emotional regulation

Read more

RESCUE- expected usefulness and willingness to participate in a trauma-informed group intervention for coping with traumatic work experiences in the emergency medical services

Emergency Medical Services personnel (EMS) are confronted with potentially highly stressful and traumatic occupational experiences, placing them at high-risk for mental disorders. Avoidant coping mechanisms, internalized and occupational stigma not only impede disclosure of and processing the incident-related stress but…

Tags: Academic research, Germany, Mental health, Therapy

Read more

Harnessing the power of biomarkers for diffuse intrinsic pontine gliomas

Nature Medicine, Published online: 12 May 2026; doi:10.1038/s41591-026-04399-2The BIOMEDE trial, although negative for its primary endpoint, illustrates the utility of adaptive trial designs and biopsy-informed tumor profiling in guiding treatment decisions and patient counseling — and provides mechanistic evidence that…

Tags: Biomarker, Medication

Read more

Brazil’s big bet on mosquitos

Nature Medicine, Published online: 12 May 2026; doi:10.1038/s41591-026-04388-5As Brazil takes its modified mosquito program from pilot to practice at national scale, what will it take to beat dengue?

Tags: Medication

Read more

Genomic epidemiology of the 2025 mpox epidemic in Sierra Leone

Nature Medicine, Published online: 12 May 2026; doi:10.1038/s41591-026-04385-8A phylogenetic analysis examined the origins of the first mpox outbreak in Sierra Leone and found evidence of an emerging lineage (G.1) that has likely descended from the Nigerian epidemic and emerged in…

Tags: Genomics, Medication

Read more

Data-Driven Decision Support in Obesity Management Commission: enabling more equitable and personalized obesity care

Nature Medicine, Published online: 12 May 2026; doi:10.1038/s41591-026-04363-0Announced in this Comment and in collaboration with Nature Medicine is the convening of the Data-Driven Decision Support in Obesity Management Commission, to promote adequate scientific evidence to support obesity management across global…

Tags: Appetite and ingestive regulation, Medication

Read more

CRISPR−Cas9 CD33-deleted allogeneic hematopoietic cell transplantation with gemtuzumab ozogamicin maintenance in AML: a phase 1/2 trial

Nature Medicine, Published online: 12 May 2026; doi:10.1038/s41591-026-04362-1In a first-in-human trial combining the transplantation of CD33-negative CRISPR-edited hematopoietic cells with the CD33-targeted antibody–drug conjugate gemtuzumab ozogamicin, all transplanted patients achieved primary engraftment, and the treatment was well tolerated.

Tags: Clinical trial, Medication

Read more

Optics-free spatial genomics for mapping mammalian brain aging by IRISeq

Nature Neuroscience, Published online: 12 May 2026; doi:10.1038/s41593-026-02293-1The authors developed an optics-free spatial genomics method to map mouse brain aging, revealing region-specific inflammation and showing that lymphocytes promote harmful interferon signaling, whereas their loss preserves ependymal cells and reshapes glial…

Tags: Genomics

Read more

The Download: a Nobel winner on AI, and the case for fixing everything

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Three things in AI to watch, according to a Nobel-winning economist A few months before he…

Tags: Cognitive focus and executive control, Government / public service, Substance abuse, Substance use, United States

Read more

Case Report: Recurrent pathogenic mutation c.110G>A in DHDDS gene

Recent studies have demonstrated the close association of mutations in the dehydrodolichyl diphosphate synthase (DHDDS) gene with neurodevelopmental disorders and the onset of epilepsy. This report describes a female patient harboring a de novo heterozygous variant c.110G>A (p.Arg37His) in the…

Tags: Academic research, Mental health

Read more