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Publisher Correction: Artificial allosteric protein switches with machine-learning-designed receptors
Nature Biotechnology, Published online: 20 July 2026; doi:10.1038/s41587-026-03263-5Publisher Correction: Artificial allosteric protein switches with machine-learning-designed receptors
Flu Virus Interaction with Host Cell Machinery Mapped Inside Infected Cells
Researchers developed a customized experimental workflow combining cross-linking mass spectrometry with AlphaFold-based structural modeling and functional assays to directly map protein-protein interactions in influenza-infected human cells. The post Flu Virus Interaction with Host Cell…
A 3-Tier AI Model for COVID-19 Triage Using Pharyngeal Images: Algorithm Development and Validation
Background: SARS-CoV-2 remains a common cause of acute respiratory illness; however, symptom-based triage poorly discriminates it from other febrile conditions. A recently developed artificial intelligence (AI)–powered pharyngeal camera acquires pharyngeal images and clinical data…
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Roundtables: Unveiling The 10 Things That Matter in AI Right Now
Listen to the session or watch below Watch a special edition of Roundtables simulcast live from EmTech AI, MIT Technology Review’s signature conference for AI leadership. Subscribers got an exclusive first look at a new list capturing 10 key technologies,…
Early life may have breathed oxygen earlier than believed
Around 2.3 billion years ago, a pivotal period known as the Great Oxidation Event set the evolutionary course for oxygen-breathing life on Earth. But MIT geobiologists and colleagues have found evidence that some early forms of life evolved the ability…
This tool could show how consciousness works
How does the physical matter in our brains translate into thoughts, sensations, and emotions? It’s hard to explore that question without neurosurgery. But in a recent paper, MIT philosopher Matthias Michel, Lincoln Lab researcher Daniel Freeman, and colleagues outline a…
A natural protein may protect the GI tract from infection
Embedded in the body’s mucosal surfaces, proteins called lectins bind to sugars found on cell surfaces. A team led by MIT chemistry professor Laura Kiessling has found that one such protein, intelectin-2, both helps fortify the mucosal barrier and offers…
The new word in home construction could be “plastics”
Single-use plastics are a persistent source of environmental pollution, and the need to house a growing global population puts increasing pressure on resources such as timber. MIT engineers have an idea that could make a dent in both problems at…
STAT+: Key GOP senators push back on Trump’s plan to cut NIH, reorganize HHS
Lawmakers seem poised to reject cuts to biomedical research and public health spending for a second straight year.
GABA-Based Target for Alzheimer’s Therapy Identified
Modulation of gamma-aminobutyric acid (GABA) signaling can restore disrupted neural balance and improve memory-related function in AD disease models. The post GABA-Based Target for Alzheimer’s Therapy Identified appeared first on Inside Precision Medicine.
Reduced bilateral auditory cortex activation during pure-tone perception in pediatric HIV
IntroductionChildren with perinatally acquired HIV (CPHIV) are at increased risk of neurodevelopmental difficulties, including hearing-related impairments, despite early initiation of antiretroviral therapy (ART). Previous studies have reported a higher prevalence of hearing loss in CPHIV compared with uninfected children; however,…
A narrative review on oxytocin at the intersection of sleep, stress, and social behavior
Sleep, stress regulation, and circadian rhythms form an interdependent network that shapes cognition, emotion, and social behavior. Disruption of any component can amplify stress sensitivity and impair emotional regulation, leading to neurobehavioral instability. This review discusses evidence from human and…
The role of sensory experience in the maturation of prefrontal cortical circuits
Sensory input during early life is crucial for brain circuitry to be appropriately wired and refined. Foundational studies in the past century established that early sensory input was required for the appropriate development of primary sensory areas. Further investigation in…
Analysis of characteristics of hospitalized patients with chronic insomnia: a single-center retrospective study
ObjectiveInsomnia is a prevalent health issue within the general population. Nonetheless, there is a paucity of research specifically addressing chronic insomnia among hospitalized patients. Consequently, the objective of this study is to investigate chronic insomnia in adult inpatients.MethodsA retrospective analysis…
Effect of a nursing-based information–motivation–behavioral model on older patients with type 2 diabetes mellitus
BackgroundOlder patients with type 2 diabetes mellitus (T2DM) frequently encounter challenges, including a diminished capacity for self-management, a high prevalence of negative emotions, and cognitive decline and physiological changes attributable to long-term disease burden, leading to compromised glycemic control and…
Number of children and maternal mental health in the context of China’s fertility policy transition: the moderating effect of employment status and the mediating effect of family environment
BackgroundHaving more children may be detrimental to maternal mental health during China’s ongoing fertility policy transition. However, under what circumstances and how number of children could be associated with maternal mental health remains understudied in China. This study examined the…
Coping under pressure: police-specific stressors and mental health in Catalonia police forces
IntroductionPolice officers are exposed to elevated psychological risks due to both operational and organizational stressors. Additionally, police officers tend to resort to avoidant coping strategies, which exacerbate poor mental health outcomes, such as burnout and PTSD.MethodsThis study aims to examine…
Iron dyshomeostasis in neuropsychiatric disorders
Iron is an indispensable element for the normal physiological function of the brain. In terms of neuronal metabolism, iron is involved in multiple critical biological processes such as oxygen transport, energy metabolism, DNA synthesis, neurotransmitter synthesis and myelin formation. Maintaining…
Is AI actually improving healthcare?
Nature Medicine, Published online: 21 April 2026; doi:10.1038/s41591-026-04329-2Is AI actually improving healthcare?
Exposure to negative physical and social factors accelerates brain aging
Nature Medicine, Published online: 21 April 2026; doi:10.1038/s41591-026-04348-zIn a study that included 18,701 people from 34 countries, 73 aggregated physical and social exposomes exhibited nonlinear, synergistic effects that accelerated brain aging. In some cases, these effects were comparable to or…
Show us the evidence for the value of medical AI
Nature Medicine, Published online: 21 April 2026; doi:10.1038/s41591-026-04389-4Claims that medical AI is improving care must be backed by appropriate evidence.
The Q-MONSTAR consortium: advancing fault-tolerant quantum computing for precision oncology
Nature Medicine, Published online: 21 April 2026; doi:10.1038/s41591-026-04346-1The Q-MONSTAR consortium: advancing fault-tolerant quantum computing for precision oncology