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Organ Aging Linked to Breakdown in Immune Cell Interaction and Senescent Neutrophil Clearance
A study in mice and in human cells found that blocking a single receptor on tissue-resident macrophages promoted clearance of accumulating senescent neutrophils, preserved the youthfulness of multiple organs in mice, and substantially slowed…
Opinion: STAT readers on the value of primary care, obesity as a disease, and more
“The real opportunity is to move beyond policies and narratives that pit specialties against one another,” presidents of the AAFP, ACP, and AAP write.
Circuit logic of oxytocin and vasopressin complementary actions
Oxytocin (OT) and vasopressin (VP) are evolutionarily conserved neuropeptides that regulate social behavior, emotional processing and physiological homeostasis. Although traditionally studied as individual modulators of affiliation, stress and autonomic function, emerging evidence indicates that…
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The Download: the state of AI, and protecting bears with drones
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Want to understand the current state of AI? Check out these charts. If you’re following AI news, you’re probably getting whiplash.…
NASA is building the first nuclear reactor-powered interplanetary spacecraft. How will it work?
MIT Technology Review Explains: Let our writers untangle the complex, messy world of technology to help you understand what’s coming next. You can read more from the series here. Just before Artemis II began its historic slingshot around the moon, Jared…
A fluoride shortage for some U.S. water systems
An experimental Medicare program, how family dynamics affect brain recovery, and other health news from Morning Rounds
Coming soon: 10 Things That Matter in AI Right Now
Each year we compile our 10 Breakthrough Technologies list, featuring our educated predictions for which technologies will have the biggest impact on how we live and work. This year, however, we had a dilemma. While our final picks encompass all…
The problem with thinking you’re part Neanderthal
You’ve probably heard some version of this idea before: that many of us have an “inner Neanderthal.” That is to say, around 45,000 years ago, when Homo sapiens first arrived in Europe, they met members of a cousin species—the broad-browed,…
For Ben Sasse, Revolution Medicines’ pancreatic cancer trial felt like his best, only option
Former Sen. Ben Sasse gives a glimpse of what it's like to be a participant in an tough but promising new drug for pancreatic cancer.
NIH-funded breakthrough shrinks CRISPR for precision delivery in the body
Smaller gene-editing system could expand treatment options for cancer, ALS and other diseases.
AI-Guided Relaxation for Hemodialysis Anxiety
Conditions: Renal Insufficiency, Chronic; Anxiety; Relaxation Therapy; Maintenance Hemodialysis; Stress, Psychological Interventions: Device: AI-Guided Relaxation Platform; Other: Standard Hemodialysis Nursing Care Sponsors: Alexandria University Not yet recruiting
Personalized Repetitive Transcranial Magnetic Stimulation (PrTMS) for Treatment of Post-Traumatic Stress Disorder (PTSD)
Conditions: Posttraumatic Stress Disorder (PTSD) Interventions: Device: Transcranial Magnetic Stimulation; Device: Transcranial Magnetic Stimulation Sham Sponsors: Massachusetts General Hospital; United States Air Force Research Laboratory Not yet recruiting
Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)
Conditions: PTSD; Post Traumatic Stress Disorder PTSD; PTSD - Post Traumatic Stress Disorder; Post Traumatic Stress Disorder; Post Traumatic Stress Disorders; Post-traumatic Stress Disorder (PTSD); Post-Traumatic Stress Disorder, PTSD Interventions: Device: non-invasive vagus nerve stimulation Sponsors: Acacia Clinics; ElectroCore INC;…
Evaluation of an Online ACT and Compassion-based Intervention for Disorders of Gut-Brain Interaction
Conditions: DGBI; Depression/Anxiety Interventions: Behavioral: Acceptance and Commitment Therapy with explicit self-compassion training; Other: Education Sponsors: Örebro University, Sweden; Sahlgrenska University Hospital; Göteborg University; Uppsala University Not yet recruiting
Trial Phase: Syndemic Adapted Medly Uganda
Conditions: Mental Health Interventions: Device: Syndemic-Adapted Medly Uganda (SAMU) Sponsors: Yale University; National Institute of Mental Health (NIMH) Not yet recruiting
Trial of Center-Based Early Start Denver Model vs. Pivotal Response Treatment in Children With Autism
Conditions: Autism Spectrum Disorder (ASD); Autism Interventions: Behavioral: Early Start Denver Model (ESDM); Behavioral: Pivotal Response Treatment (PRT); Behavioral: Developmental Reciprocity Treatment (DRT) Sponsors: Stanford University; John and Marcia Goldman Foundation Not yet recruiting
Want to understand the current state of AI? Check out these charts.
If you’re following AI news, you’re probably getting whiplash. AI is a gold rush. AI is a bubble. AI is taking your job. AI can’t even read a clock. The 2026 AI Index from Stanford University’s Institute for Human-Centered Artificial…
Author Correction: Real-time surveillance system for patient deterioration: a pragmatic cluster-randomized controlled trial
Nature Medicine, Published online: 13 April 2026; doi:10.1038/s41591-026-04382-xAuthor Correction: Real-time surveillance system for patient deterioration: a pragmatic cluster-randomized controlled trial
Designing Psychologically Grounded Artificial Intelligence for Supporting Bystander-Based Cyberaggression Intervention: Mixed Methods Exploratory Study
Background: Cyberaggression poses a growing threat to mental health, contributing to increased distress, reduced self-esteem, and other adverse psychosocial outcomes. Although bystander intervention can mitigate the escalation and impact of cyberaggression, individuals often lack the confidence, strategies, or language to…
STAT+: Maryland state affordability board sets its first price cap for a medicine
The board will now oversee a process to lower the cost of the type 2 diabetes medicine Jardiance by January 2027.
STAT+: FDA pushes drugmakers to report missing clinical trial results
FDA officials said an internal analysis found results were not submitted for nearly 30% of studies “highly likely” to fall under mandatory reporting requirements.
STAT+: Federal judge tosses California No Surprises Act lawsuit against HaloMD
HaloMD is a middleman that became the top filer of out-of-network billing disputes on behalf of medical providers.
STAT+: Access granted: CMS greenlights more than 150 participants for chronic care experiment
CMS greenlights more than 150 digital health companies for its ACCESS experiment, a new program for tech-backed chronic care with outcome-aligned payments.