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Population-scale genomic medicine with the Hong Kong Genome Project
Nature Medicine, Published online: 15 May 2026; doi:10.1038/s41591-026-04410-wPart of the Hong Kong Genome Project, genomic analyses of more than 20,000 participants provide information on clinically relevant variants for the Chinese population and offer insights on the implementation of genomic medicine…
Parsing autism spectrum heterogeneity through fMRI
Nature Neuroscience, Published online: 15 May 2026; doi:10.1038/s41593-026-02269-1Autism is remarkably heterogeneous, posing a long-standing challenge for linking genetics to brain dynamics. A cross-species study identifies two principal dysconnectivity signatures across 20 mouse models of autism risk, each associated with distinct…
Autism subtypes identified using cross-species functional connectivity analyses
Nature Neuroscience, Published online: 15 May 2026; doi:10.1038/s41593-026-02287-zPagani et al. used cross-species fMRI to reveal two autism subtypes, characterized by lower and higher brain connectivity and linked to synaptic and immune-related pathways, respectively.
Excitatory synapses onto axonic spines jump-start action potentials and route information flow
Nature Neuroscience, Published online: 15 May 2026; doi:10.1038/s41593-026-02282-4The axon initial segment was known to receive GABAergic synaptic inputs. Yang et al. show that it can be excited directly via specialized ‘axonic spines’. These spines thus boost neuronal firing and act…
How Chinese short dramas became AI content machines
In a dimly lit bedroom, a frightened young woman is thrown onto a bed by a tall, muscular man. He grabs her hand, and flame-like vines crawl across her body, fusing with her flesh. She levitates, then drops. A dragon-shaped…
The world is on track to miss its health targets
Every year the World Health Organization publishes a global health statistics report. It features the numbers behind world health trends and, importantly, assesses whether we’re on track to reach ambitious goals set in 2015. It’s a bit like a health…
Opinion: I’m 73. I wish my pills wouldn’t keep changing colors and shapes
Pharmaceutical companies, generic manufacturers, and pharmacists should be more careful about changing how pills look.
Why isn’t alcohol seen as a public health emergency?
Why isn't alcohol seen as a public health emergency? Alex Hogan talks to STAT's Isabella Cueto and Lev Facher about their new series on this week's STATus Report.
Opinion: Tributes to Craig Venter and the genomics race are missing something important
A race, two rivals, a photo finish? Former National Human Genome Research Institute archivist explains what Craig Venter tributes are missing.
STAT+: Top U.S. officials pressured Germany to pay more for prescription drugs
It's a key piece of Trump's effort to secure lower drug prices for U.S. patients.
DOJ accuses Yale and UCLA medical schools of discriminating against white and Asian applicants
The Justice Department sent a letter to Yale School of Medicine on Thursday, alleging it was illegally discriminating against applicants who are not Black or Hispanic, following a similar missive…
Retail-Grade Weighted Blanket Effectiveness on ADHD-related Sleep Disturbances (BEAD)
Conditions: ADHD - Attention Deficit Disorder With Hyperactivity Interventions: Device: Sleep Intervention with weighted device Sponsors: University Hospital Bispebjerg and Frederiksberg Not yet recruiting
Online Evaluation of the Diagnostic Accuracy of BlinkLab’s Digital Assessments for Autism
Conditions: Autism; Autism Spectrum Disorder; Autism Spectrum Disorder (ASD); Neurodevelopmental Conditions Interventions: Diagnostic Test: BlinkLab Dx1; Behavioral: Retrospective Neurodevelopmental Diagnostic Assessment Sponsors: Blinklab Limited Recruiting
Use of Low Doses of Interleukin-2 in Autism Spectrum Disorders
Conditions: Autism Spectrum Disorder Interventions: Drug: ILT-101 ld-(IL2); Drug: NaCl (0,9%) Sponsors: Assistance Publique - Hôpitaux de Paris; Iltoo Pharma Not yet recruiting
Research on the Efficacy and Safety of Targeted Suprachiasmatic Nucleus Electrical Stimulation for Improving Metabolic Disorders in Patients With Stable Bipolar Disorder Comorbid With Obesity
Conditions: Bipolar Disorder (BD) Interventions: Other: Temporal Interference Stimulation; Other: Sham Temporal Interference Stimulation Arm Description Sponsors: First Affiliated Hospital of Zhejiang University Recruiting
Acupuncture Treament in Children With Tic Disorders
Conditions: Tic Disorder, Childhood Interventions: Other: Acupuncture; Behavioral: Comprehensive Behavioral Intervention for Tics (CBIT) Sponsors: Meizhou People's Hospital Not yet recruiting
Researchers identify first suite of human antibodies against measles virus
NIH-funded study lays foundation for antibody-based measles treatment.
Family psychoeducation to support patients with psychotic illness: two-year outcomes from a pre–post longitudinal pilot study
BackgroundPsychoeducation for families of young adults with psychosis is an evidence-based intervention that alleviates carer burden. The implementation of programming is limited, leaving family carers shouldering a heavy burden without appropriate support.ObjectiveThis pre-post longitudinal pilot study evaluated the preliminary outcomes…
Accelerated Himalayan river meandering and dynamics due to climate change
Science, Volume 392, Issue 6799, May 2026.