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New national action plan targets gaps at the intersection of mental health and criminal justice.
FOR IMMEDIATE RELEASE OTTAWA, ON – The Mental Health Commission of Canada (the Commission) today released “Finding New Pathways: An action plan for criminal justice and mental health in Canada”. The plan provides an evidence-based…
Kinase Droplets Activate Growth Signals, Path for Cancer Therapy
Cellular phase separation, a mechanism that organizes biomolecules into dense, liquid-like condensates, may play a previously underappreciated role in regulating kinase activity, offering therapeutic applications. The post Kinase Droplets Activate Growth Signals, Path for Cancer Therapy…
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RecoveryWorks: vocational support services for recovery capital growth
This paper introduces RecoveryWorks, a multi-system recovery and vocational support program designed to expand the therapeutic landscape of recovery by increasing access to career development resources that support meaningful employment. In contrast to vocational approaches that prioritize rapid job placement,…
Tryptophan modulates the impact of prolactin on insomnia in perimenopausal women: a cross-sectional study
BackgroundInsomnia is highly prevalent among perimenopausal women and exerts detrimental effects on physical health, psychological well-being, and overall quality of life. However, its underlying mechanisms remain incompletely understood. This cross-sectional study aimed to identify factors associated with insomnia in perimenopausal…
Research trends and knowledge mapping of transcranial direct current stimulation in depression: a bibliometric study based on web of science, Scopus, and PubMed (2000-2025)
BackgroundDepressive disorders are clinically heterogeneous and mechanistically complex psychiatric conditions. Transcranial direct current stimulation (tDCS), a key non-invasive neuromodulation technique, has expanded rapidly in both therapeutic application and mechanistic research. However, the field is marked by rapid publication growth, thematic…
Case Report: Prism for PTSD in severe traumatic brain injury with psychiatric comorbidities: two cases
BackgroundTraumatic brain injury (TBI) with post-traumatic stress disorder (PTSD) is treatment-resistant, with conventional psychotherapy showing limited efficacy due to neurocognitive impairments.Case SummaryWe report two patients with severe TBI and psychiatric comorbidities treated with Prism neurofeedback.Case 144-year-old female, 35 years post-childhood…
TxPert: using multiple knowledge graphs for prediction of transcriptomic perturbation effects
Nature Biotechnology, Published online: 01 May 2026; doi:10.1038/s41587-026-03113-4TxPert predicts unseen single transcriptomic perturbations with accuracy approaching split-half experimental reproducibility.
DNA-guided CRISPR–Cas12a effectors for programmable RNA recognition and cleavage
Nature Biotechnology, Published online: 01 May 2026; doi:10.1038/s41587-026-03120-5Synthetic DNA guides (crDNA) reprogram Cas12a nucleases for RNA targeting.
Rethinking triage for febrile children in low-resource settings
Nature Medicine, Published online: 01 May 2026; doi:10.1038/s41591-026-04387-6Integrating clinical data with simple physiological measures or biomarkers improves triage of febrile children and could reshape frontline care in resource-limited settings.
Brazilian elimination of mother-to-child HIV transmission: lessons for large-scale global health systems
Nature Medicine, Published online: 01 May 2026; doi:10.1038/s41591-026-04373-yBrazilian elimination of mother-to-child HIV transmission: lessons for large-scale global health systems
A communication subspace relays context-dependent actions from human prefrontal to motor cortex
Nature Neuroscience, Published online: 01 May 2026; doi:10.1038/s41593-026-02290-4Context-dependent behavior selects actions according to task demands. Using direct brain recordings in humans, Binish et al. uncover how coordinated population activity efficiently channels information from prefrontal to motor cortex.
Inexpensive seafloor-hopping submersibles could stoke deep-sea science—and mining
Smack dab between Australia and South America, the US National Oceanic and Atmospheric Administration (NOAA) research vessel Rainier is currently on a mission to map more than 8,000 square nautical miles of the Pacific seafloor in search of critical mineral…
A new US phone network for Christians aims to block porn and gender-related content
A new US-wide cell phone network marketed to Christians is set to launch next week. It blocks porn, which experts in network security say marks the first time a US cell plan has used network-level blocking for such content that…
Trump’s mass firing just dealt another blow to American science
This past week delivered another gut punch for science in the US. This time, the target was the National Science Foundation—a federal agency that funds major research projects to the tune of around $9 billion. The foundation’s efforts were overseen…
Opinion: America is worrying about fertility again. But it’s not really about families
Where the state once worried about too many births, it now worries about too few.
STAT+: Her daughter Mila got a bespoke medicine. Now she’s starting a new biotech to make more
Efforts to make customized medicines at scale have hit commercial and regulatory roadblocks. Julia Vintarello is trying again.
‘Forever chemicals’ in baby formula? Scientists unpack FDA results
FDA review confirmed overall safety of 16 brands of baby formula. In a STAT Q&A, experts unpack what low-level PFAS findings mean to worried moms.
Opinion: The psychedelic revolution is leaving behind people of color
Psychedelics’ potential as a form of treatment is virtually unmatched. But their promise faces both scientific uncertainty and thorny political questions.
Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression
Conditions: Major Depression Interventions: Drug: D-Cycloserine (DCS); Device: Continuous theta-burst stimulation (cTBS); Device: Transcranial Magnetic Stimulation Sham; Drug: Memantine; Drug: Lorazepam (drug); Drug: Baclofen; Drug: Placebo Sponsors: Mclean Hospital; National Institute of Mental Health (NIMH) Recruiting
Electrophysiological Biomarkers and Treatment Response to Accelerated Transcranial Magnetic Stimulation in Patients With Obsessive-Compulsive Disorder
Conditions: Obsessive - Compulsive Disorder; Transcranial Magnetic Stimilation; Intermittent Theta Burst Stimulation; EEG Interventions: Device: iTBS TMS Sponsors: Istanbul University - Cerrahpasa Recruiting
Predictive Value of Early Peritraumatic Distress Screening for Childbirth-PTSD Following Unplanned Cesarean Delivery
Conditions: Post Traumatic Stress Disorder; Post Partum Depression; Acute Stress Symptoms Interventions: Other: Postpartum Psychological Screening Sponsors: University of British Columbia; Women's Health Research Institute of British Columbia Not yet recruiting
PB-18 Probiotic for Mild to Moderate Depression
Conditions: Depressive Disorder Interventions: Dietary Supplement: Bifidobacterium; Other: Placebo Sponsors: First Affiliated Hospital of Zhejiang University Not yet recruiting