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New national action plan targets gaps at the intersection of mental health and criminal justice.
FOR IMMEDIATE RELEASE OTTAWA, ON – The Mental Health Commission of Canada (the Commission) today released “Finding New Pathways: An action plan for criminal justice and mental health in Canada”. The plan provides an evidence-based…
Kinase Droplets Activate Growth Signals, Path for Cancer Therapy
Cellular phase separation, a mechanism that organizes biomolecules into dense, liquid-like condensates, may play a previously underappreciated role in regulating kinase activity, offering therapeutic applications. The post Kinase Droplets Activate Growth Signals, Path for Cancer Therapy…
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Oral administration of kratom leaf extract alleviates anxiety-like behavior, urinary bladder pain, voiding dysfunction, and bladder hypercontractility via attenuating muscarinic receptor response in male mice exposed to chronic water avoidance stress
Psychological stress causes and deteriorates interstitial cystitis/painful bladder syndrome with urinary frequency, incontinence, bladder pain and urgency. The major alkaloid of kratom (Mitragyna speciosa), mitragynine, shows analgesic, anxiolytic, and smooth muscle relaxant effects. However, the effects of kratom leaf extract…
Psychometric properties of Lithuanian translation of the self-report version of the Liebowitz social anxiety scale in young adult sample
BackgroundSocial anxiety disorder starts in adolescence or young adulthood and may have damaging effects on psychosocial development of the individual. Any intervention starts from assessment and the Liebowitz social anxiety scale with later developed self-report version is a valuable tool…
The temporal stability of core symptoms of social media addiction and their comorbidity with anxiety and depression in adolescents: a longitudinal network analysis
IntroductionSocial media addiction (SMA) is often comorbid with anxiety and depression. This study examined the temporal stability of core SMA symptoms and the bridging symptoms with anxiety and depression.MethodsA total of 1,240 adolescents (179 males, 1,061 females; mean age =…
Expanding the phenotypic spectrum of Xq28 duplication involving MECP2: a familial case report
X-linked intellectual disability (XLID) is a well-recognized group of neurodevelopmental disorders, with pathogenic variants in X-chromosomal genes accounting for approximately 16% of intellectual disability cases in males. Clinical expression in females is variable and depends on patterns of X-chromosome inactivation.…
Effectiveness and mechanisms of Intensive Short-Term Dynamic Psychotherapy for treatment-resistant depression: a reanalysis of a randomized controlled trial
IntroductionIntensive Short-Term Dynamic Psychotherapy has shown promising effects for treatment-resistant depression, but it remains unclear whether its hypothesized mechanisms — reducing emotional repression, negative affect, and psychological distress — actually mediate treatment outcomes.MethodsWe reanalyzed publicly available data from a randomized…
Group CBT targeting hostile attribution bias in adolescents and young adults with ASD traits
BackgroundAdolescence is characterized by heightened self-consciousness and sensitivity to social evaluations. During this period, hostile attribution bias—interpreting ambiguous social cues as hostile—can lower quality of life (QOL) and contribute to future mental health problems. Adolescents with autism spectrum disorder (ASD)…
Synthetic biology’s uncertain regulatory future in the wake of Loper Bright Enterprises v. Raimondo
Nature Biotechnology, Published online: 22 April 2026; doi:10.1038/s41587-026-03114-3The US Supreme Court’s decision in Loper Bright Enterprises v. Raimondo, along with federal spending cuts, may limit the potential of synthetic biology to provide innovative solutions for environmental challenges, medicine and biomanufacturing.
Deeper is not always better in plasma proteomics
Nature Biotechnology, Published online: 22 April 2026; doi:10.1038/s41587-026-03106-3This Comment discusses depth, robustness and bias in plasma proteomics, concluding that increasing the depth of coverage does not necessarily translate to quantitative robustness.
Reference-free discovery with barcoded single-cell sequencing
Nature Biotechnology, Published online: 22 April 2026; doi:10.1038/s41587-026-03084-6sc-SPLASH extends reference-free analysis to barcoded single-cell and spatial transcriptomics data.
The future of diagnostics in Africa
Nature Medicine, Published online: 22 April 2026; doi:10.1038/s41591-026-04308-7The authors propose five high-priority areas to close the current gaps in diagnostic testing, providing a path to self-reliance in health security and universal healthcare in Africa.
The ghost of tuberculosis past
Nature Medicine, Published online: 22 April 2026; doi:10.1038/s41591-026-04356-zThe analysis of the 100 Million Brazilian database reveals that a past tuberculosis diagnosis increases the risk of death up to 14 years later regardless of treatment outcome, which should prompt urgent prioritization…
Moderna continues bird flu vax study, but limits work in the U.S.
Flu shot no longer mandated for U.S. troops, "healthy" snacks, and other news from Morning Rounds
AI needs a strong data fabric to deliver business value
Artificial intelligence is moving quickly in the enterprise, from experimentation to everyday use. Organizations are deploying copilots, agents, and predictive systems across finance, supply chains, human resources, and customer operations. By the end of 2025, half of companies used AI…
Los Angeles is finally going underground
Los Angeles deserves its reputation as the quintessential car city—the rhythms of its 2,200 square miles are dictated by wide boulevards and concrete arcs of freeways. But it once had a world-class rail transit system, and for the last three…
There is no nature anymore
When people talk about “nature,” they’re generally talking about things that aren’t made by human beings. Rocks. Reefs. Red wolves. But while there is plenty of God’s creation to go around, it is hard to think of anything on Earth…
One town’s scheme to get rid of its geese
“Pull over!” I order my brother one sunny February afternoon. Our target is in sight: a gaggle of Canada geese, pecking at grass near the dog park. As I approach, tiptoeing over their grayish-white poop, I notice that one bird…
3 things Michelle Kim is into right now
Isegye Idol If you thought K-pop was weird, virtual idols—humans who perform as anime-style digital characters via motion capture—will blow your mind. My favorite is a girl group called Isegye Idol, created by Woowakgood, a Korean VTuber (a streamer who…
Opinion: The CDC’s ‘disease detective’ program turns 75
The CDC’s EIS program has trained more than 4,300 people to be the next generation of public health leaders.
Opinion: NASA’s plans for living in space should prioritize immunology and infectious disease
Infectious diseases could pose serious risks for interplanetary travelers.
Are MAHA snacks really better for you? Nutrition experts parse a grocery aisle gold rush
From protein Pop-Tarts to avocado-oil chips, a MAHA-fueled snack revolution promises healthier eating. Experts say it may mostly be illusion.