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3083 results

A computational pipeline for a neurotransmitter-centric analysis of the effects of psychiatric medication on EEG spectral power

IntroductionTraditional pharmaco-electroencephalography (EEG) studies have mainly examined the effects of psychotropic medications at the level of individual drugs or broad drug classes, limiting biological specificity and clinical translation. This study aimed to determine whether modeling EEG spectral power changes according…

Tags: Academic research, Fear and threat response, Medication, Mood and emotional regulation

Read more

Outcomes from the ASPEN intervention program: a randomized clinical trial of a culturally adapted parent-mediated intervention program in low-resource settings

This randomized controlled study examined the efficacy of a culturally adapted parent-mediated intervention for parents and young children with autism (n = 45) from low-resource households (ClinicalTrials.gov Identifier: NCT04505488). Families from these settings are often left out of autism intervention studies and…

Tags: Academic research, Autism, Clinical trial

Read more

Burnout and perceived health in medical residents after the COVID-19 pandemic: a single-center cross-sectional study

IntroductionResidents have a high risk of burnout during the training period. The COVID-19 pandemic has had a great impact on work conditions and health of medical residents. We therefore estimated the prevalence of post-pandemic burnout and perceived health, and their…

Tags: Academic research, Cognitive focus and executive control, Healthcare provider, Mental health

Read more

Diagnosis of prolonged grief disorder among older adults: mapping physicians’ knowledge and practice, and evaluating the effectiveness of a brief targeted training program

BackgroundProlonged Grief Disorder (PGD) is a psychiatric diagnosis with significant implications for individuals and society. Familiarity with its diagnostic criteria and recommended interventions is essential for early detection and effective treatment. As aging naturally involves multiple losses, older adults are…

Tags: Academic research, Clinical trial, Mental health

Read more

Voltage dynamics of cortical dendrites in vivo

Nature Neuroscience, Published online: 19 June 2026; doi:10.1038/s41593-026-02339-4Simultaneous voltage imaging of soma and dendrites in layer 2/3 cortical neurons in live mice reveals rich dynamics of spike back-propagation, with amplitude shaped by spiking history, dendrite location and behavioral state.

Tags: None

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Tryptamine from wake-active monoaminergic neurons regulates sleep homeostasis

Nature Neuroscience, Published online: 19 June 2026; doi:10.1038/s41593-026-02332-xCao et al. identify tryptamine as a sleep signal in mice. Wake-active monoaminergic neurons release tryptamine, which binds to GPR139 in POA neurons that suppress wake-promoting neurons. GPR139 agonists could be a new…

Tags: Medication, Sleep and arousal regulation

Read more

A startup claims it broke through a bottleneck that’s holding back LLMs

Miami-based AI startup Subquadratic came out of stealth mode last month with a huge claim. It announced that it had solved a mathematical bottleneck that had been holding back large language models for almost a decade. The details were thin,…

Tags: Academic research, Biotech, Cognitive focus and executive control

Read more

Brain-computer interface trials are taking off

This week, I covered the story of Casey Harrell—a man with ALS who is “the first power user” of a brain implant, according to the researchers who worked with him. Harrell is paralyzed and unable to speak coherently without the…

Tags: Academic research, Australia, Medical device, Netherlands

Read more

The inevitable weakness of metrics

There are plenty of useful things a metric can reveal. There are even more it can obscure or corrupt. It took me well over a decade of tracking my own life in ever greater detail to fully appreciate this duality,…

Tags: Medication, Private company, Sleep and arousal regulation, Social and attachment drive, United States

Read more

News Feed

News

Disease
Functional Domain
Type
Source
Reset filters

3083 results

A computational pipeline for a neurotransmitter-centric analysis of the effects of psychiatric medication on EEG spectral power

IntroductionTraditional pharmaco-electroencephalography (EEG) studies have mainly examined the effects of psychotropic medications at the level of individual drugs or broad drug classes, limiting biological specificity and clinical translation. This study aimed to determine whether modeling EEG spectral power changes according…

Tags: Academic research, Fear and threat response, Medication, Mood and emotional regulation

Read more

Outcomes from the ASPEN intervention program: a randomized clinical trial of a culturally adapted parent-mediated intervention program in low-resource settings

This randomized controlled study examined the efficacy of a culturally adapted parent-mediated intervention for parents and young children with autism (n = 45) from low-resource households (ClinicalTrials.gov Identifier: NCT04505488). Families from these settings are often left out of autism intervention studies and…

Tags: Academic research, Autism, Clinical trial

Read more

Burnout and perceived health in medical residents after the COVID-19 pandemic: a single-center cross-sectional study

IntroductionResidents have a high risk of burnout during the training period. The COVID-19 pandemic has had a great impact on work conditions and health of medical residents. We therefore estimated the prevalence of post-pandemic burnout and perceived health, and their…

Tags: Academic research, Cognitive focus and executive control, Healthcare provider, Mental health

Read more

Diagnosis of prolonged grief disorder among older adults: mapping physicians’ knowledge and practice, and evaluating the effectiveness of a brief targeted training program

BackgroundProlonged Grief Disorder (PGD) is a psychiatric diagnosis with significant implications for individuals and society. Familiarity with its diagnostic criteria and recommended interventions is essential for early detection and effective treatment. As aging naturally involves multiple losses, older adults are…

Tags: Academic research, Clinical trial, Mental health

Read more

Voltage dynamics of cortical dendrites in vivo

Nature Neuroscience, Published online: 19 June 2026; doi:10.1038/s41593-026-02339-4Simultaneous voltage imaging of soma and dendrites in layer 2/3 cortical neurons in live mice reveals rich dynamics of spike back-propagation, with amplitude shaped by spiking history, dendrite location and behavioral state.

Tags: None

Read more

Tryptamine from wake-active monoaminergic neurons regulates sleep homeostasis

Nature Neuroscience, Published online: 19 June 2026; doi:10.1038/s41593-026-02332-xCao et al. identify tryptamine as a sleep signal in mice. Wake-active monoaminergic neurons release tryptamine, which binds to GPR139 in POA neurons that suppress wake-promoting neurons. GPR139 agonists could be a new…

Tags: Medication, Sleep and arousal regulation

Read more

A startup claims it broke through a bottleneck that’s holding back LLMs

Miami-based AI startup Subquadratic came out of stealth mode last month with a huge claim. It announced that it had solved a mathematical bottleneck that had been holding back large language models for almost a decade. The details were thin,…

Tags: Academic research, Biotech, Cognitive focus and executive control

Read more

Brain-computer interface trials are taking off

This week, I covered the story of Casey Harrell—a man with ALS who is “the first power user” of a brain implant, according to the researchers who worked with him. Harrell is paralyzed and unable to speak coherently without the…

Tags: Academic research, Australia, Medical device, Netherlands

Read more

The inevitable weakness of metrics

There are plenty of useful things a metric can reveal. There are even more it can obscure or corrupt. It took me well over a decade of tracking my own life in ever greater detail to fully appreciate this duality,…

Tags: Medication, Private company, Sleep and arousal regulation, Social and attachment drive, United States

Read more