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New national action plan targets gaps at the intersection of mental health and criminal justice.
FOR IMMEDIATE RELEASE OTTAWA, ON – The Mental Health Commission of Canada (the Commission) today released “Finding New Pathways: An action plan for criminal justice and mental health in Canada”. The plan provides an evidence-based…
Kinase Droplets Activate Growth Signals, Path for Cancer Therapy
Cellular phase separation, a mechanism that organizes biomolecules into dense, liquid-like condensates, may play a previously underappreciated role in regulating kinase activity, offering therapeutic applications. The post Kinase Droplets Activate Growth Signals, Path for Cancer Therapy…
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This tool could show how consciousness works
How does the physical matter in our brains translate into thoughts, sensations, and emotions? It’s hard to explore that question without neurosurgery. But in a recent paper, MIT philosopher Matthias Michel, Lincoln Lab researcher Daniel Freeman, and colleagues outline a…
A natural protein may protect the GI tract from infection
Embedded in the body’s mucosal surfaces, proteins called lectins bind to sugars found on cell surfaces. A team led by MIT chemistry professor Laura Kiessling has found that one such protein, intelectin-2, both helps fortify the mucosal barrier and offers…
The new word in home construction could be “plastics”
Single-use plastics are a persistent source of environmental pollution, and the need to house a growing global population puts increasing pressure on resources such as timber. MIT engineers have an idea that could make a dent in both problems at…
STAT+: Key GOP senators push back on Trump’s plan to cut NIH, reorganize HHS
Lawmakers seem poised to reject cuts to biomedical research and public health spending for a second straight year.
GABA-Based Target for Alzheimer’s Therapy Identified
Modulation of gamma-aminobutyric acid (GABA) signaling can restore disrupted neural balance and improve memory-related function in AD disease models. The post GABA-Based Target for Alzheimer’s Therapy Identified appeared first on Inside Precision Medicine.
Reduced bilateral auditory cortex activation during pure-tone perception in pediatric HIV
IntroductionChildren with perinatally acquired HIV (CPHIV) are at increased risk of neurodevelopmental difficulties, including hearing-related impairments, despite early initiation of antiretroviral therapy (ART). Previous studies have reported a higher prevalence of hearing loss in CPHIV compared with uninfected children; however,…
A narrative review on oxytocin at the intersection of sleep, stress, and social behavior
Sleep, stress regulation, and circadian rhythms form an interdependent network that shapes cognition, emotion, and social behavior. Disruption of any component can amplify stress sensitivity and impair emotional regulation, leading to neurobehavioral instability. This review discusses evidence from human and…
The role of sensory experience in the maturation of prefrontal cortical circuits
Sensory input during early life is crucial for brain circuitry to be appropriately wired and refined. Foundational studies in the past century established that early sensory input was required for the appropriate development of primary sensory areas. Further investigation in…
Analysis of characteristics of hospitalized patients with chronic insomnia: a single-center retrospective study
ObjectiveInsomnia is a prevalent health issue within the general population. Nonetheless, there is a paucity of research specifically addressing chronic insomnia among hospitalized patients. Consequently, the objective of this study is to investigate chronic insomnia in adult inpatients.MethodsA retrospective analysis…
Effect of a nursing-based information–motivation–behavioral model on older patients with type 2 diabetes mellitus
BackgroundOlder patients with type 2 diabetes mellitus (T2DM) frequently encounter challenges, including a diminished capacity for self-management, a high prevalence of negative emotions, and cognitive decline and physiological changes attributable to long-term disease burden, leading to compromised glycemic control and…
Number of children and maternal mental health in the context of China’s fertility policy transition: the moderating effect of employment status and the mediating effect of family environment
BackgroundHaving more children may be detrimental to maternal mental health during China’s ongoing fertility policy transition. However, under what circumstances and how number of children could be associated with maternal mental health remains understudied in China. This study examined the…
Coping under pressure: police-specific stressors and mental health in Catalonia police forces
IntroductionPolice officers are exposed to elevated psychological risks due to both operational and organizational stressors. Additionally, police officers tend to resort to avoidant coping strategies, which exacerbate poor mental health outcomes, such as burnout and PTSD.MethodsThis study aims to examine…
Iron dyshomeostasis in neuropsychiatric disorders
Iron is an indispensable element for the normal physiological function of the brain. In terms of neuronal metabolism, iron is involved in multiple critical biological processes such as oxygen transport, energy metabolism, DNA synthesis, neurotransmitter synthesis and myelin formation. Maintaining…
Is AI actually improving healthcare?
Nature Medicine, Published online: 21 April 2026; doi:10.1038/s41591-026-04329-2Is AI actually improving healthcare?
The Q-MONSTAR consortium: advancing fault-tolerant quantum computing for precision oncology
Nature Medicine, Published online: 21 April 2026; doi:10.1038/s41591-026-04346-1The Q-MONSTAR consortium: advancing fault-tolerant quantum computing for precision oncology
Exposure to negative physical and social factors accelerates brain aging
Nature Medicine, Published online: 21 April 2026; doi:10.1038/s41591-026-04348-zIn a study that included 18,701 people from 34 countries, 73 aggregated physical and social exposomes exhibited nonlinear, synergistic effects that accelerated brain aging. In some cases, these effects were comparable to or…
Show us the evidence for the value of medical AI
Nature Medicine, Published online: 21 April 2026; doi:10.1038/s41591-026-04389-4Claims that medical AI is improving care must be backed by appropriate evidence.
Modifying exposure to plastic-associated chemicals in daily living
Nature Medicine, Published online: 21 April 2026; doi:10.1038/s41591-026-04349-yA study shows that extensively limiting plastic use in food systems, diet and daily life can reduce exposure to plastic-associated chemicals such as phthalates and bisphenols, indicating that large-scale regulatory actions are needed…
Biophysical modeling of excitation/inhibition balance and conversion to psychosis in the clinical high risk syndrome
Reduced mismatch negativity (MMN) and P300 event-related potential (ERP) components are widely replicated in schizophrenia and are also observed in individuals at clinical high risk for psychosis (CHR-P) who subsequently convert to psychosis. It is unknown whether they reflect changes…