News Feed
New national action plan targets gaps at the intersection of mental health and criminal justice.
FOR IMMEDIATE RELEASE OTTAWA, ON – The Mental Health Commission of Canada (the Commission) today released “Finding New Pathways: An action plan for criminal justice and mental health in Canada”. The plan provides an evidence-based…
Kinase Droplets Activate Growth Signals, Path for Cancer Therapy
Cellular phase separation, a mechanism that organizes biomolecules into dense, liquid-like condensates, may play a previously underappreciated role in regulating kinase activity, offering therapeutic applications. The post Kinase Droplets Activate Growth Signals, Path for Cancer Therapy…
News
1477 results
Opinion: Behind every miracle drug is a story
“In every drug, there is a much larger story to tell about health and medicine and society and business and economics,” says Thomas Goetz.
Carea adds miscarriage support feature to maternal health app
Carea has launched a digital support tool within its app to provide guidance and mental health support for women following pregnancy loss.
Single Arm, Monocentric, Pilot Feasibility Study on an Interactive Virtual Reality Program in 20 Complex In-clinic Palliative Care Patients
Conditions: Palliative Care; Refractory Pain; Anxiety; Depression Disorders; Fatigue, Mental; Psychological Distress Interventions: Device: ZenctuaryVR+ Interactive Virtual Reality Sponsors: University Hospital, Strasbourg, France; MOME, University of Arts and Design Not yet recruiting
A Mindfulness-Based Stress Reduction Training Program Model
Conditions: Depression; Anxiety; Stress; Well-Being, Psychological Interventions: Behavioral: The mindfulness group-"Mindfulness-Based Stress Reduction Program"; Behavioral: The life skills workshop group-"Lifestyle Management and Well-being Workshop" Sponsors: Istanbul Medeniyet University Not yet recruiting
Teen Vulnerability to Irritability: Brain and Estrogen Changes
Conditions: Depression - Major Depressive Disorder; Irritability Interventions: Drug: Kurvelo; Drug: Placebo COC Sponsors: University of North Carolina, Chapel Hill; Foundation of Hope for the Research and Treatment of Mental Illness Not yet recruiting
THE EFFECTS OF AN ONLINE FAMILY PSYCHOEDUCATION PROGRAM ON EXPRESSED EMOTION OF FAMILY MEMBERS AND MEDICATION ADHERENCE OF PATIENTS WITH FIRST-EPISODE SCHIZOPHRENIA
Conditions: First- Episode Schizophrenia Interventions: Behavioral: Mobile based family psychoeducation program Sponsors: Mahidol University Completed
NIH-funded AI model predicts cancer survival from single-cell tumor data
Study links specific cell populations to patient risk in melanoma and liver cancer.
Dr. Jonathan M. Green selected as CEO of the NIH Clinical Center
The NIH Clinical Center is the largest research hospital in the world.
Efficacy and Safety of Sertraline Combined With Lactobacillus Crispatus in Adolescents With Depression : A Multicenter Randomized Controlled Trial
Conditions: Major Depressive Disorder (MDD); Probiotic Intervention Interventions: Combination Product: Sertraline combined with Lactobacillus crispatus; Combination Product: Sertraline combined with placebo Sponsors: First Affiliated Hospital of Chongqing Medical University Not yet recruiting
Out-of-frame CBX3::ALK fusion drives ALK activation and therapy response
Hang et al. identify an out-of-frame CBX3::ALK fusion in metastatic melanoma that generates functional ALK isoforms through alternative translation start sites. This study demonstrates that rare noncanonical out-of-frame fusions can be oncogenic and therapeutically actionable, highlighting an analytic blind spot…
Combination immunotherapy for colorectal cancer: Clinical applications, rationale, challenges, and future perspectives
Fei et al. review combination immunotherapy strategies for colorectal cancer, focusing on overcoming resistance in pMMR/MSS/MSI-L tumors. They highlight integrating ICIs with chemotherapy, targeted therapy, and radiotherapy and discuss insights into the tumor microenvironment and biomarkers to improve outcomes.
Shinya Yamanaka
Dr. Shinya Yamanaka is recognized for the generation of induced pluripotent stem cells (iPSCs) from fibroblasts by a combination of multiple transcription factors, and he won the Nobel Prize in Physiology or Medicine in 2012 jointly with Sir John B.…
Identifying the role of NLRP3 inflammasome in stroke progression and outcome before recanalization
Bellut et al. show that the NLRP3 inflammasome drives hyperacute inflammation and infarct progression during large vessel occlusion in stroke. Pharmacological inhibition reduces infarct growth in mice. NLRP3-positive cells in human pial blood before thrombectomy correlate with clinical outcome and…
The healthy human global project – Hong Kong: A community-based cross-sectional study of a healthy Asian population
A deeply phenotyped healthy Hong Kong cohort reveals age- and sex-dependent immune, clinical, and lifestyle variation, highlighting population-specific differences and the need to extend systems immunology frameworks beyond European ancestry.
STAT+: With successful trials, Roche takes its MS drug to regulators, but safety questions loom
The Swiss drugmaker Roche presented the latest data for its experimental multiple sclerosis drug, setting the stage for the company to seek approval.
STAT+: From Revolution Medicines, more strong data on KRAS drug and a glimpse of a ‘novel class’ beyond it
A company that is changing the outlook on pancreatic cancer has more promising data for treatments near-term and for a generation beyond.
STAT+: Kyverna Therapeutics plans to submit cell therapy for stiff person syndrome for FDA approval
A one-time cell therapy from Kyverna Therapeutics for stiff person syndrome, a rare disease, improved mobility and reduced disabilities in a late-stage trial.
STAT+: At AACR, more strong results for Revolution Medicine’s KRAS drug, plus assurance from NCI’s director
At AACR, Revolution Medicines presented more eye-catching data about its KRAS-targeting treatment, and Anthony Letai declared the state of cancer research steady.
Roundtables: Unveiling The 10 Things That Matter in AI Right Now
Listen to the session or watch below Watch a special edition of Roundtables simulcast live from EmTech AI, MIT Technology Review’s signature conference for AI leadership. Subscribers got an exclusive first look at a new list capturing 10 key technologies,…
Early life may have breathed oxygen earlier than believed
Around 2.3 billion years ago, a pivotal period known as the Great Oxidation Event set the evolutionary course for oxygen-breathing life on Earth. But MIT geobiologists and colleagues have found evidence that some early forms of life evolved the ability…