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1477 results

Impact of Prescribed and Self-Selected Music Interventions on Stress, Sleep, Heart Rate Variability, and Brain Connectivity in Surgeons Using 7-Tesla Functional Magnetic Resonance Imaging and Wearable Actigraphy: Multimodal Feasibility Randomized Controlled Trial

Background: Stress, sleep deprivation, and burnout are significant safety risks for acute care surgeons, negatively impacting performance, well-being, and clinical outcomes. Objective: This pilot randomized controlled trial aimed to measure neurophysiological effects of prescribed music (PM) and self-selected music (SSM)…

Tags: Academic research, Anxiety, Clinical trial, Sleep and arousal regulation

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Exploring Influencing Factors of Medication Adherence Among Chinese Patients With Alzheimer Disease: Delphi Study Informing Future Artificial Intelligence–Supported Interventions

Background: Alzheimer disease (AD) affects cognition, treatment adherence, family connections, and health care resource allocation. Most patients with AD have low adherence to medication therapy due to the limitations associated with cognitive impairment. Therefore, increasing the involvement of patients and…

Tags: Academic research, Medication, Mental health

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Development of iGET Living, a Digital Graded Exposure Intervention for Youth With Chronic Pain: Multiphase User-Centered Design and Pilot Study

Background: Pediatric chronic pain affects up to one-third of youth and is associated with significant disruptions in social, emotional, and behavioral functioning. Although behavioral treatments are effective, access remains limited due to geographic, financial, and systemic barriers. Digital behavioral health…

Tags: Academic research, Clinical trial, Mental health

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Tags: Medication, Mental health, Social and attachment drive

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Tags: Reality testing and perceptual stability, Schizophrenia spectrum, Substance abuse, Substance use

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Pie Day 2026

Ellie’s Pi Day post: https://mitadmissions.org/blogs/entry/pi-day-2026-food-institute/ How Ellie orchestrated the baking of 30 pies: https://mitadmissions.org/blogs/entry/behind-the-scenes-of-thirty-pies/

Tags: None

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Tags: Medication, Mental health, Social and attachment drive

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EEG-based stroke severity classification using higher-order topological features and graph convolutional networks

IntroductionElectroencephalography (EEG)-based stroke analysis has mainly relied on conventional signal and network descriptors, while higher-order brain network structures remain insufficiently characterized.MethodsWe used persistent homology to extract cycle-based topological features from EEG functional networks, capturing higher-order organization with reduced sensitivity to…

Tags: Cognitive focus and executive control

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Cerebral blood flow and functional connectivity immediate changes following intradermal acupuncture in major depressive disorder

BackgroundAcupuncture has been increasingly applied as an adjunctive treatment for major depressive disorder (MDD), yet its central neurobiological mechanisms remain insufficiently understood. Cerebral blood flow (CBF) and functional connectivity strength (FCS) provide complementary perspectives on regional metabolic activity and large-scale…

Tags: Academic research, Cognitive focus and executive control, Depression, Medication, Mood and emotional regulation

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Effect of low-intensity focused ultrasound on hippocampus of alcohol addicted mice: a preliminary study

Alcohol addiction is a chronic relapsing brain disorder characterized by significant neurobiological changes, particularly within the hippocampus, which mediates emotional regulation and reward-seeking behavior. Previous studies have shown that alcohol-induced neuronal injury contributes to withdrawal-associated anxiety and persistent alcohol preference.…

Tags: Academic research, Anxiety, Dissociation and identity integration, Mood and emotional regulation, Substance abuse, Substance use

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Transcutaneous auricular vagus nerve stimulation to alleviate metformin-associated gastrointestinal adverse events and optimize glycaemic control: a randomized, sham-controlled pilot trial protocol

BackgroundGastrointestinal adverse events (GI AEs) are the main dose-limiting side effects of metformin in type 2 diabetes mellitus (T2DM), reducing adherence and compromising long-term glycaemic control. Current strategies (dose adjustment or combination therapy) seldom address both tolerability and sustained metabolic…

Tags: Appetite and ingestive regulation, Biomarker, Clinical trial, Mood and emotional regulation

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The patterns of relapse and abstinence: using machine learning to identify a multidimensional signature of long-term outcome after inpatient alcohol withdrawal treatment

AimsA machine learning approach to identify a multidimensional signature associated with relapse and long-term outcome in alcohol dependence treatment.DesignIn this observational naturalistic study, inpatients with alcohol dependence received qualified detoxification plus CBT (Cognitive Behavioral Therapy) and were followed up 6-months…

Tags: CBT, Substance abuse, Substance use

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Psychometric validation of the revised Chinese version of the Dimensional Anhedonia Rating Scale in psychiatric outpatients

ObjectiveTo refine the Chinese version of the Dimensional Anhedonia Rating Scale (DARS) and evaluate the psychometric properties of the Revised Chinese DARS (RC-DARS) in a large sample of first-visit psychiatric outpatients.MethodsThe study was conducted in two sequential phases at a…

Tags: Academic research, Anxiety, Depression, Healthcare provider, Mood and emotional regulation, Sleep and arousal regulation

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Interoceptive dysfunction and its neural correlates in schizophrenia: protocol for a cross-sectional multimodal MRI study

BackgroundInteroception—the perception and integration of internal bodily signals—is fundamental to emotion regulation, bodily self-awareness, and predictive coding. Emerging evidence suggests that interoceptive disturbances may contribute to core psychopathological features of schizophrenia. Our research group recently conducted a systematic review and…

Tags: Academic research, Clinical trial, Fear and threat response, Schizophrenia spectrum, Sensory processing

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