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New national action plan targets gaps at the intersection of mental health and criminal justice.
FOR IMMEDIATE RELEASE OTTAWA, ON – The Mental Health Commission of Canada (the Commission) today released “Finding New Pathways: An action plan for criminal justice and mental health in Canada”. The plan provides an evidence-based…
Kinase Droplets Activate Growth Signals, Path for Cancer Therapy
Cellular phase separation, a mechanism that organizes biomolecules into dense, liquid-like condensates, may play a previously underappreciated role in regulating kinase activity, offering therapeutic applications. The post Kinase Droplets Activate Growth Signals, Path for Cancer Therapy…
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Impact of Prescribed and Self-Selected Music Interventions on Stress, Sleep, Heart Rate Variability, and Brain Connectivity in Surgeons Using 7-Tesla Functional Magnetic Resonance Imaging and Wearable Actigraphy: Multimodal Feasibility Randomized Controlled Trial
Background: Stress, sleep deprivation, and burnout are significant safety risks for acute care surgeons, negatively impacting performance, well-being, and clinical outcomes. Objective: This pilot randomized controlled trial aimed to measure neurophysiological effects of prescribed music (PM) and self-selected music (SSM)…
Exploring Influencing Factors of Medication Adherence Among Chinese Patients With Alzheimer Disease: Delphi Study Informing Future Artificial Intelligence–Supported Interventions
Background: Alzheimer disease (AD) affects cognition, treatment adherence, family connections, and health care resource allocation. Most patients with AD have low adherence to medication therapy due to the limitations associated with cognitive impairment. Therefore, increasing the involvement of patients and…
Development of iGET Living, a Digital Graded Exposure Intervention for Youth With Chronic Pain: Multiphase User-Centered Design and Pilot Study
Background: Pediatric chronic pain affects up to one-third of youth and is associated with significant disruptions in social, emotional, and behavioral functioning. Although behavioral treatments are effective, access remains limited due to geographic, financial, and systemic barriers. Digital behavioral health…
STAT+: A pancreatic cancer expert on why Revolution Medicines’ study could ‘open up a new era’ of treatment
"I do think it's a revolution," said Paul Oberstein of NYU Langone's Perlmutter Cancer Center.
Pie Day 2026
Ellie’s Pi Day post: https://mitadmissions.org/blogs/entry/pi-day-2026-food-institute/ How Ellie orchestrated the baking of 30 pies: https://mitadmissions.org/blogs/entry/behind-the-scenes-of-thirty-pies/
STAT+: FDA eyes expanding testosterone therapy for libido
New research questions GLP-1's purpose, a pancreatic cancer breakthrough, and more biotech news from The Readout
The deadly consequences of ICE detention
New research challenges what we know about GLP-1s, vaccine skepticism, and more health news from Morning Rounds
The Download: bad news for inner Neanderthals, and AI warfare’s human illusion
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. The problem with thinking you’re part Neanderthal There’s a theory that many of us have an…
EEG-based stroke severity classification using higher-order topological features and graph convolutional networks
IntroductionElectroencephalography (EEG)-based stroke analysis has mainly relied on conventional signal and network descriptors, while higher-order brain network structures remain insufficiently characterized.MethodsWe used persistent homology to extract cycle-based topological features from EEG functional networks, capturing higher-order organization with reduced sensitivity to…
Cerebral blood flow and functional connectivity immediate changes following intradermal acupuncture in major depressive disorder
BackgroundAcupuncture has been increasingly applied as an adjunctive treatment for major depressive disorder (MDD), yet its central neurobiological mechanisms remain insufficiently understood. Cerebral blood flow (CBF) and functional connectivity strength (FCS) provide complementary perspectives on regional metabolic activity and large-scale…
Effect of low-intensity focused ultrasound on hippocampus of alcohol addicted mice: a preliminary study
Alcohol addiction is a chronic relapsing brain disorder characterized by significant neurobiological changes, particularly within the hippocampus, which mediates emotional regulation and reward-seeking behavior. Previous studies have shown that alcohol-induced neuronal injury contributes to withdrawal-associated anxiety and persistent alcohol preference.…
Transcutaneous auricular vagus nerve stimulation to alleviate metformin-associated gastrointestinal adverse events and optimize glycaemic control: a randomized, sham-controlled pilot trial protocol
BackgroundGastrointestinal adverse events (GI AEs) are the main dose-limiting side effects of metformin in type 2 diabetes mellitus (T2DM), reducing adherence and compromising long-term glycaemic control. Current strategies (dose adjustment or combination therapy) seldom address both tolerability and sustained metabolic…
The patterns of relapse and abstinence: using machine learning to identify a multidimensional signature of long-term outcome after inpatient alcohol withdrawal treatment
AimsA machine learning approach to identify a multidimensional signature associated with relapse and long-term outcome in alcohol dependence treatment.DesignIn this observational naturalistic study, inpatients with alcohol dependence received qualified detoxification plus CBT (Cognitive Behavioral Therapy) and were followed up 6-months…
Psychometric validation of the revised Chinese version of the Dimensional Anhedonia Rating Scale in psychiatric outpatients
ObjectiveTo refine the Chinese version of the Dimensional Anhedonia Rating Scale (DARS) and evaluate the psychometric properties of the Revised Chinese DARS (RC-DARS) in a large sample of first-visit psychiatric outpatients.MethodsThe study was conducted in two sequential phases at a…
Interoceptive dysfunction and its neural correlates in schizophrenia: protocol for a cross-sectional multimodal MRI study
BackgroundInteroception—the perception and integration of internal bodily signals—is fundamental to emotion regulation, bodily self-awareness, and predictive coding. Emerging evidence suggests that interoceptive disturbances may contribute to core psychopathological features of schizophrenia. Our research group recently conducted a systematic review and…
Electroconvulsive therapy in an adolescent with dissociative identity disorder and depression: a case report
BackgroundDissociative identity disorder (DID) is a psychiatric condition characterized by the existence of at least two distinct identities. This disorder often serves as a defense mechanism, a response to severe childhood trauma, aimed at protecting the individual from overwhelming emotions…

