News Feed
Constructing the history of a contested region
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
Spawning Season: An Experiment in Queer Parenthood
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
News
3090 results
STAT+: ARCH-launched Neumora stops depression program
A new AI model to improve trial enrollment, importing drugs from Canada, and more biotech news from The Readout
STAT+: Pharmalittle: We’re reading about Medicare and obesity drugs, Germany’s pricing plans, and more
Weight loss drugs will be available through Medicare starting next month, thanks to a program that is supposed to be temporary but may be difficult to end
Turning Rejection Into a Roadmap: Advice for the Next Generation of Mental Health Leaders
Aaliyah Nadirah Madyun, program director at the Stavros Niarchos Foundation (SNF) Global Center for Child and Adolescent Mental Health at the Child Mind Institute, recently sat down with Tom Osborn, founder of the Shamiri Institute and an International Advisory Board…
The Download: the first brain implant power user and South Korea’s AI obsession
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. This man with ALS is the first “power user” of a brain implant that lets him…
How supplement use changed over decades
Medicare-funded weight loss, Utah's lower drunk driving limit, and more health news from Morning Rounds
Assessment of tenecteplase target-associated pathogenic mechanisms underlying depression in acute ischemic stroke patients: insights from artificial intelligence-driven multi-omics analysis and in vitro validation
BackgroundAs a first-line treatment for acute ischemic stroke (AIS), tenecteplase (TNK) can cause adverse effects, such as depression, in AIS patients.ObjectiveThis study aims to elucidate the TNK target-related pathogenic mechanisms underlying major depressive disorder (MDD) in AIS patients.MethodsBy analyzing six…
Screening the optimal rTSMS frequency to orchestrate immune-fibrotic remodeling for adult spinal cord repair
IntroductionThe clinical translation of magnetic stimulation for central nervous system trauma is severely hindered by “parameter ambiguity”—the lack of evidence-based screen of stimulation protocol. Repetitive trans-spinal magnetic stimulation (rTSMS) holds therapeutic promise, yet its frequency-dependent effects on the complex spinal…
CEST MRI reveals nicotine-induced alterations in glutamate-associated molecular connectivity in the mouse brain
IntroductionUnderstanding how neurotransmitter systems organize into large-scale networks is essential for elucidating the mechanisms through which drugs, diseases, and behavioral states alter brain function. Existing imaging modalities such as functional MRI (fMRI) and positron emission tomography (PET) provide measures of…
Brain protein burden is related to intravoxel incoherent motion: PET-MR imaging study
IntroductionDysfunction in brain protein clearance mechanisms is thought to contribute to many neurodegenerative diseases, yet non-invasive assessment of these mechanisms in humans remains challenging. This study is the first to examine whether intravoxel incoherent motion (IVIM) diffusion MRI metrics, measures…
Multimodal behavioral phenotyping for depressive-spectrum classification and severity estimation using eye tracking, facial behavior, and transcript-derived language
IntroductionDepression assessment remains largely dependent on symptom reports and clinician judgment, while objective tools for depressive-spectrum stratification and severity estimation remain limited. Existing digital and multimodal depression-detection studies often focus on binary case-control classification, handle missing modalities incompletely, provide limited…
Generative AI as interactional infrastructure for meaning-centered care in later life
Generative artificial intelligence (GenAI) and large language models are rapidly entering mental health research and service delivery, yet their dominant use remains symptom-centric, emphasizing screening, classification, triage, and risk detection. For older adults, mental health is often inseparable from existential…
Generative AI for pre-consultation mental health triage in disorders of gut-brain interaction
Disorders of gut-brain interaction (DGBI) are common, disabling, and frequently accompanied by anxiety, depressive symptoms, sleep disturbance, symptom-related fear, and repeated health care use. In routine gastroenterology practice, these problems are often recognized late, after fragmented histories, multiple visits, and…
From digital access to social connectedness: the digital divide, bonding social capital, and depressive symptoms among older adults in China
IntroductionAs population aging and digital transformation continue simultaneously in China, the digital divide among older adults has become an increasingly important social issue. This study examines the associations between multiple dimensions of the digital divide and depressive symptoms among older…
Experiences and wellbeing of family members and carers, regarding PARCS across Victoria
IntroductionWhen consumers experience mental health crises, carers are often key supporters and are also impacted significantly themselves. The Prevention and Recovery Care (PARC) model offers a community-based residential program for consumers, in times of mental health crisis. The potential of…
Author Correction: Quantification and transcriptome profiling reveal abundant, dynamic and translatable dephospho-CoA-capped RNAs
Nature Biotechnology, Published online: 16 June 2026; doi:10.1038/s41587-026-03215-zAuthor Correction: Quantification and transcriptome profiling reveal abundant, dynamic and translatable dephospho-CoA-capped RNAs
Engineered heart muscle passes early clinical milestone
Nature Medicine, Published online: 16 June 2026; doi:10.1038/d41591-026-00031-5Engineered heart muscle allografts derived from induced pluripotent stem cells show promising early outcomes in patients with treatment-refractory advanced heart failure with reduced left ventricular ejection fraction, in support of further clinical investigation.
Author Correction: Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study
Nature Medicine, Published online: 16 June 2026; doi:10.1038/s41591-026-04513-4Author Correction: Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study
Red-shifted GRAB acetylcholine sensors for multiplex imaging in vivo
Nature Neuroscience, Published online: 16 June 2026; doi:10.1038/s41593-026-02325-wThe authors develop red fluorescent GRAB acetylcholine (ACh) sensors and highlight rACh1h as a robust tool for multiplex recording together with various green sensors. Using fiber photometry, mesoscopic imaging and two-photon imaging, rACh1h…
STAT+: Verge Labs’ new AI model solves patient stratification problems for neurology clinical trials
As the saying goes, one man’s trash is another man’s treasure. Or as Verge Labs might put it, one company’s failed clinical trial … is that same company’s new AI…
News Feed
Constructing the history of a contested region
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
Spawning Season: An Experiment in Queer Parenthood
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
News
3090 results
STAT+: ARCH-launched Neumora stops depression program
A new AI model to improve trial enrollment, importing drugs from Canada, and more biotech news from The Readout
STAT+: Pharmalittle: We’re reading about Medicare and obesity drugs, Germany’s pricing plans, and more
Weight loss drugs will be available through Medicare starting next month, thanks to a program that is supposed to be temporary but may be difficult to end
Turning Rejection Into a Roadmap: Advice for the Next Generation of Mental Health Leaders
Aaliyah Nadirah Madyun, program director at the Stavros Niarchos Foundation (SNF) Global Center for Child and Adolescent Mental Health at the Child Mind Institute, recently sat down with Tom Osborn, founder of the Shamiri Institute and an International Advisory Board…
The Download: the first brain implant power user and South Korea’s AI obsession
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. This man with ALS is the first “power user” of a brain implant that lets him…
How supplement use changed over decades
Medicare-funded weight loss, Utah's lower drunk driving limit, and more health news from Morning Rounds
Assessment of tenecteplase target-associated pathogenic mechanisms underlying depression in acute ischemic stroke patients: insights from artificial intelligence-driven multi-omics analysis and in vitro validation
BackgroundAs a first-line treatment for acute ischemic stroke (AIS), tenecteplase (TNK) can cause adverse effects, such as depression, in AIS patients.ObjectiveThis study aims to elucidate the TNK target-related pathogenic mechanisms underlying major depressive disorder (MDD) in AIS patients.MethodsBy analyzing six…
Screening the optimal rTSMS frequency to orchestrate immune-fibrotic remodeling for adult spinal cord repair
IntroductionThe clinical translation of magnetic stimulation for central nervous system trauma is severely hindered by “parameter ambiguity”—the lack of evidence-based screen of stimulation protocol. Repetitive trans-spinal magnetic stimulation (rTSMS) holds therapeutic promise, yet its frequency-dependent effects on the complex spinal…
CEST MRI reveals nicotine-induced alterations in glutamate-associated molecular connectivity in the mouse brain
IntroductionUnderstanding how neurotransmitter systems organize into large-scale networks is essential for elucidating the mechanisms through which drugs, diseases, and behavioral states alter brain function. Existing imaging modalities such as functional MRI (fMRI) and positron emission tomography (PET) provide measures of…
Brain protein burden is related to intravoxel incoherent motion: PET-MR imaging study
IntroductionDysfunction in brain protein clearance mechanisms is thought to contribute to many neurodegenerative diseases, yet non-invasive assessment of these mechanisms in humans remains challenging. This study is the first to examine whether intravoxel incoherent motion (IVIM) diffusion MRI metrics, measures…
Multimodal behavioral phenotyping for depressive-spectrum classification and severity estimation using eye tracking, facial behavior, and transcript-derived language
IntroductionDepression assessment remains largely dependent on symptom reports and clinician judgment, while objective tools for depressive-spectrum stratification and severity estimation remain limited. Existing digital and multimodal depression-detection studies often focus on binary case-control classification, handle missing modalities incompletely, provide limited…
Generative AI as interactional infrastructure for meaning-centered care in later life
Generative artificial intelligence (GenAI) and large language models are rapidly entering mental health research and service delivery, yet their dominant use remains symptom-centric, emphasizing screening, classification, triage, and risk detection. For older adults, mental health is often inseparable from existential…
Generative AI for pre-consultation mental health triage in disorders of gut-brain interaction
Disorders of gut-brain interaction (DGBI) are common, disabling, and frequently accompanied by anxiety, depressive symptoms, sleep disturbance, symptom-related fear, and repeated health care use. In routine gastroenterology practice, these problems are often recognized late, after fragmented histories, multiple visits, and…
From digital access to social connectedness: the digital divide, bonding social capital, and depressive symptoms among older adults in China
IntroductionAs population aging and digital transformation continue simultaneously in China, the digital divide among older adults has become an increasingly important social issue. This study examines the associations between multiple dimensions of the digital divide and depressive symptoms among older…
Experiences and wellbeing of family members and carers, regarding PARCS across Victoria
IntroductionWhen consumers experience mental health crises, carers are often key supporters and are also impacted significantly themselves. The Prevention and Recovery Care (PARC) model offers a community-based residential program for consumers, in times of mental health crisis. The potential of…
Author Correction: Quantification and transcriptome profiling reveal abundant, dynamic and translatable dephospho-CoA-capped RNAs
Nature Biotechnology, Published online: 16 June 2026; doi:10.1038/s41587-026-03215-zAuthor Correction: Quantification and transcriptome profiling reveal abundant, dynamic and translatable dephospho-CoA-capped RNAs
Engineered heart muscle passes early clinical milestone
Nature Medicine, Published online: 16 June 2026; doi:10.1038/d41591-026-00031-5Engineered heart muscle allografts derived from induced pluripotent stem cells show promising early outcomes in patients with treatment-refractory advanced heart failure with reduced left ventricular ejection fraction, in support of further clinical investigation.
Author Correction: Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study
Nature Medicine, Published online: 16 June 2026; doi:10.1038/s41591-026-04513-4Author Correction: Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study
Red-shifted GRAB acetylcholine sensors for multiplex imaging in vivo
Nature Neuroscience, Published online: 16 June 2026; doi:10.1038/s41593-026-02325-wThe authors develop red fluorescent GRAB acetylcholine (ACh) sensors and highlight rACh1h as a robust tool for multiplex recording together with various green sensors. Using fiber photometry, mesoscopic imaging and two-photon imaging, rACh1h…
STAT+: Verge Labs’ new AI model solves patient stratification problems for neurology clinical trials
As the saying goes, one man’s trash is another man’s treasure. Or as Verge Labs might put it, one company’s failed clinical trial … is that same company’s new AI…