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New national action plan targets gaps at the intersection of mental health and criminal justice.
FOR IMMEDIATE RELEASE OTTAWA, ON – The Mental Health Commission of Canada (the Commission) today released “Finding New Pathways: An action plan for criminal justice and mental health in Canada”. The plan provides an evidence-based…
Kinase Droplets Activate Growth Signals, Path for Cancer Therapy
Cellular phase separation, a mechanism that organizes biomolecules into dense, liquid-like condensates, may play a previously underappreciated role in regulating kinase activity, offering therapeutic applications. The post Kinase Droplets Activate Growth Signals, Path for Cancer Therapy…
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Closing the gap on antifungal resistance
Nature Medicine, Published online: 15 April 2026; doi:10.1038/s41591-026-04334-5Drug-resistant fungal disease must be addressed in the 2026 update to the Global Action Plan on Antimicrobial Resistance
Rapid expansion of genotype D1.1 A(H5N1) influenza viruses in wild birds across North America during the 2024 migratory season
Nature Medicine, Published online: 15 April 2026; doi:10.1038/s41591-026-04300-1Using active and passive genomic surveillance, researchers observed the rapid spread of high pathogenicity avian influenza H5N1 D1.1 viruses in wild birds during the 2024 migratory season, which coincided with detection in humans,…
Proteomic risk score for early prediction of kidney disease progression in individuals with APOL1 high-risk genotypes
Nature Medicine, Published online: 15 April 2026; doi:10.1038/s41591-026-04337-2For individuals with APOL1 high-risk genotypes, which are enriched in individuals of African ancestry, a nine-protein proteomic risk score enables early prediction of kidney disease progression and may, thereby, enable early intervention.
An acetylated Tau-174 CSF biomarker discriminates between TDP-43 and tau pathology in patients with frontotemporal lobar degeneration
Nature Medicine, Published online: 15 April 2026; doi:10.1038/s41591-026-04341-6A new cerebrospinal fluid biomarker, AcTau174, was elevated in frontotemporal lobar degeneration with TAR DNA-binding protein (FTLD-TDP), distinguishing this pathology from FTLD-Tau, and was associated with disease severity and progression in FTLD-TDP.
Amyloid-β-driven glymphatic dysfunction in Alzheimer’s disease model mice is driven by Ca2+-mediated increases in astrocytic cholesterol
Nature Neuroscience, Published online: 15 April 2026; doi:10.1038/s41593-026-02261-9This study uncovers how amyloid-β boosts astrocyte calcium activity, increasing cholesterol and disrupting brain waste clearance in an Alzheimer’s disease mouse model. Targeting astrocyte calcium or cholesterol restores clearance and improves cognition.
Trump DOJ report says Biden administration treated anti-abortion protestors unfairly
New CDC tetanus shot analysis, AI scans for heart risk, and more health news from Morning Rounds
Cyberscammers are bypassing banks’ security with illicit tools sold on Telegram
From inside a money-laundering center in Cambodia, an employee opens a popular Vietnamese banking app on his phone. The app asks him to upload a photo associated with the account, so he clicks on a picture of a 30-something Asian…
Call for expert – Research & report on deinstitutionalisation and psychosocial disabilities in Europe
Seeking an expert to support the development of a study on deinstitutionalisation (DI) and psychosocial disabilities in Europe, exploring how mental health systems and disability-inclusive policies can be better aligned at the EU level. The post Call for expert –…
STAT+: New Bain biotech startup, building on BMS drugs, gets a name and a CEO
Beeline Medicine is focused on development of five inflammatory and immune disorder drugs, starting with a potential daily pill for lupus.
No one’s sure if synthetic mirror life will kill us all
For four days in February 2019, some 30 synthetic biologists and ethicists hunkered down at a conference center in Northern Virginia to brainstorm high-risk, cutting-edge, irresistibly exciting ideas that the National Science Foundation should fund. By the end of the…
STAT+: Flawed study on the antidepressant Paxil came with a cautionary note — if you knew how to find it
When scientific journals publish expressions of concerns, they have an obligation to do so prominently, Ed Silverman writes.
Opinion: Hosting the ‘intellectual wrestling match’ between MAHA, public health
“These sides aren't talking to each other. And there's a lot riding on it”: the podcast trying to bridge MAHA and public health.
STAT+: AI could check millions of CT scans for heart risk. Who will pay for it?
New AI tools could screen existing CT scans to asses risk for heart disease. But, who'll pay for it, and will it improve health outcomes?
Building trust in the AI era with privacy-led UX
The practice of privacy-led user experience (UX) is a design philosophy that treats transparency around data collection and usage as an integral part of the customer relationship. An undertapped opportunity in digital marketing, privacy-led UX treats user consent not as…
Five Digits Test – Validation of a Neuropsychological Test of Inhibition for Patients With Neuropsychiatric Conditions
Conditions: Autism; ADHD Interventions: Diagnostic Test: Five Digits Test Sponsors: Umeå University; Region Västerbotten Recruiting
Analysis of Influencing Factors for the Development of PTSD in Emergency Department Trauma Patients
Conditions: Trauma Patients; PTSD Sponsors: The First Affiliated Hospital of Air Force Medicial University Not yet recruiting
NASA is building the first nuclear reactor-powered interplanetary spacecraft. How will it work?
MIT Technology Review Explains: Let our writers untangle the complex, messy world of technology to help you understand what’s coming next. You can read more from the series here. Just before Artemis II began its historic slingshot around the moon, Jared…
User Experience and Early Clinical Outcomes of a Mental Wellness Chatbot for Depression and Anxiety: Pilot Evaluation Mixed Methods Study
Background: Artificial intelligence–powered conversational agents (ie, chatbots) are increasingly popular outlets for users seeking psychological support, yet little is known about how users experience early-stage prototypes or which therapeutic processes contribute to clinical improvement. A transparent evaluation of emerging chatbot…
Development of Virtual Mental Health Stepped Care Service for a Heart Failure Remote Management Program: Qualitative Descriptive Study
Background: Depression is highly prevalent yet undertreated among people living with heart failure, indicating barriers to mental health services. Although various digital mental health interventions have been developed to detect, treat, and manage depression in this population, these interventions have…