News Feed
Constructing the history of a contested region
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
Spawning Season: An Experiment in Queer Parenthood
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
News
3090 results
Identity rupture and reconstruction in post-stroke PTSD: a patient journey map
ObjectiveTo identify the core psychological rehabilitation needs of post-stroke Post-Traumatic Stress Disorder patients based on a patient-family-nurse triad-verified journey map, and to provide references for developing precise nursing intervention strategies.MethodsA descriptive qualitative research method was adopted. From July 2025 to…
Expressive writing combined with digital cognitive therapy in patients with schizophrenia: a narrative review of efficacy, linguistic phenotypes, and adherence modulators
Schizophrenia involves emotional and cognitive deficits that are often unresponsive to medication, emphasizing the need for effective psychosocial rehabilitation. This narrative review and conceptual perspective explores the potential integration of expressive writing (EW) and digital cognitive therapy (DCT) as a…
Cultural and intergenerational pathways between family alcohol use, trauma exposure, and probable PTSD in Taiwanese adolescents
BackgroundPosttraumatic stress disorder (PTSD) and alcohol use (AU) frequently co-occur, yet little is known about how family drinking patterns shape trauma exposure and PTSD risk in non-Western and Indigenous adolescent populations. Taiwan’s multi-ethnic eastern region—home to Amis and Atayal Indigenous…
Functional MRI evidence of brain alterations in premenstrual dysphoric disorder: a systematic review
IntroductionPremenstrual Dysphoric Disorder (PMDD) affects approximately 1.6% of women of reproductive age and significantly impacts quality of life. Despite its prevalence, the underlying pathophysiology remains incompletely understood. First-line treatment typically involves selective serotonin reuptake inhibitors (SSRIs); however, approximately 40 percent…
Spectral EEG-guided adaptive neuromodulation for social anxiety disorder, performance-only subtype: a case report
Social anxiety disorder (SAD) is often complicated by anticipatory anxiety, hyperarousal, and variability in response to first-line treatments such as cognitive behavioral therapy (CBT) and pharmacotherapy. These limitations highlight the need for adjunctive modalities capable of enhancing the magnitude and…
Marked for destruction
Nature Biotechnology, Published online: 04 June 2026; doi:10.1038/s41587-026-03182-5The significance of the first FDA-approved PROTAC lies not in proving that targeted protein degradation is superior to conventional therapies, but in proving that degrading proteins is possible as a therapeutic.
A socially assistive robot to support mental wellbeing in LGBTQ+ young people at risk of self-harm: a randomized controlled trial
Nature Medicine, Published online: 04 June 2026; doi:10.1038/s41591-026-04422-6A randomized controlled trial integrating Purrble, a socially assistive tactile robot, into safety planning found that LGBTQ+ youth at risk of self-harm experienced improvements in Difficulties in Emotion Regulation Scale and fewer depressive…
AAV gene therapy for homozygous familial hypercholesterolemia: a phase 1 trial
Nature Medicine, Published online: 04 June 2026; doi:10.1038/s41591-026-04441-3After preclinical testing, a phase 1 trial involving three individuals with familial hypercholesterolemia demonstrated preliminary evidence for the safety and efficacy of AAV8-mediated LDL receptor gene therapy.
Spinal cord stimulation for upper limb motor function in people with chronic post-stroke hemiparesis: a feasibility trial
Nature Medicine, Published online: 04 June 2026; doi:10.1038/s41591-026-04435-1In this feasibility clinical trial, the authors show that epidural stimulation of the cervical spinal cord safely improved strength, function and spasticity in seven people with arm hemiparesis.
Human microglial transitions at the Aβ–tau inflection point associate with divergent pathways to dementia and resilience
Nature Medicine, Published online: 04 June 2026; doi:10.1038/s41591-026-04393-8Microglia cellular changes underlie divergent resilience-associated mechanisms in human aging.
Aberrant tau accumulation caused by MAPT mutations induces early pathological changes in axonal transport that are rescued by p38α inhibition
Nature Neuroscience, Published online: 04 June 2026; doi:10.1038/s41593-026-02266-4Imaging axonal transport in vivo in the mouse cortex reveals that deficits in axonal transport arise at early stages of tau pathology, are caused by enlarged tau envelopes and are reversed by inhibiting…
How courts are coping with a flood of AI-generated lawsuits
Most days in her chambers, Judge Maritza Braswell, a federal magistrate judge in Colorado, sifts through stacks of documents written by people without a lawyer. Many of them can’t afford to hire a lawyer, and others have cases too weak…
STAT+: Does Revolution Medicines’ pancreatic cancer drug have even greater potential?
Revolution Medicines' pancreatic cancer drug has not yet been approved — and already talk has shifted to how (and when) its use might be expanded.
What happens at a longevity festival?
What happens at a longevity festival? On this week's STATus Report, Alex Hogan gets a dispatch from STAT's Sarah Todd.
Opinion: Grail’s multi-cancer early detection trial was negative. But as an oncologist, I see more to this story
An oncologist shares three lessons from the world’s first randomized trial on a multi-cancer early detection.
Opinion: Lawmakers promised cancer patients would be protected from Medicaid cuts. Now CMS says otherwise
“One of the cancer community’s worst fears is coming to pass,” writes Gwen Nichols of Blood Cancer United.
STAT+: After hospitals, patients get a turn to bring AI into the doctor’s office
Ambient scribes were the first large-scale application of AI in health care. Now developers are pitching them as diligent note-takers for patients.
Transcranial Temporal Interference Stimulation for Children With Autism Spectrum Disorders
Conditions: Autism Spectrum Disorder Interventions: Device: transcranial Temporal Interference Stimulation Sponsors: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Recruiting
A Positron Emission Tomography (PET) Study to Evaluate Dopamine D2 and D3 Receptor Occupancy by SIPI6398
Conditions: Schizophrenia Disorder Interventions: Drug: SIPI6398 Tablets Sponsors: Shanghai Zhongze Therapeutics Co., Ltd.; Yale University Not yet recruiting
A Prospective Comparative Study Evaluating the Safety and Efficacy of Transurethral Thulium Fiber Laser, Holmium Laser and Bipolar Enucleation of Large Sized Prostate
Conditions: Benign Prostatic Hyperplasia (BPH); Lower Urinary Tract Symptom; Bladder Outlet Obstruction Interventions: Procedure: Endoscopic Enucleation of the Prostate; Procedure: Endoscopic Enucleation of the Prostate; Procedure: Endoscopic Enucleation of the Prostate Sponsors: Tanta University Recruiting
News Feed
Constructing the history of a contested region
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
Spawning Season: An Experiment in Queer Parenthood
Science, Volume 394, Issue 6823, Page 492-492, October 2026.
News
3090 results
Identity rupture and reconstruction in post-stroke PTSD: a patient journey map
ObjectiveTo identify the core psychological rehabilitation needs of post-stroke Post-Traumatic Stress Disorder patients based on a patient-family-nurse triad-verified journey map, and to provide references for developing precise nursing intervention strategies.MethodsA descriptive qualitative research method was adopted. From July 2025 to…
Expressive writing combined with digital cognitive therapy in patients with schizophrenia: a narrative review of efficacy, linguistic phenotypes, and adherence modulators
Schizophrenia involves emotional and cognitive deficits that are often unresponsive to medication, emphasizing the need for effective psychosocial rehabilitation. This narrative review and conceptual perspective explores the potential integration of expressive writing (EW) and digital cognitive therapy (DCT) as a…
Cultural and intergenerational pathways between family alcohol use, trauma exposure, and probable PTSD in Taiwanese adolescents
BackgroundPosttraumatic stress disorder (PTSD) and alcohol use (AU) frequently co-occur, yet little is known about how family drinking patterns shape trauma exposure and PTSD risk in non-Western and Indigenous adolescent populations. Taiwan’s multi-ethnic eastern region—home to Amis and Atayal Indigenous…
Functional MRI evidence of brain alterations in premenstrual dysphoric disorder: a systematic review
IntroductionPremenstrual Dysphoric Disorder (PMDD) affects approximately 1.6% of women of reproductive age and significantly impacts quality of life. Despite its prevalence, the underlying pathophysiology remains incompletely understood. First-line treatment typically involves selective serotonin reuptake inhibitors (SSRIs); however, approximately 40 percent…
Spectral EEG-guided adaptive neuromodulation for social anxiety disorder, performance-only subtype: a case report
Social anxiety disorder (SAD) is often complicated by anticipatory anxiety, hyperarousal, and variability in response to first-line treatments such as cognitive behavioral therapy (CBT) and pharmacotherapy. These limitations highlight the need for adjunctive modalities capable of enhancing the magnitude and…
Marked for destruction
Nature Biotechnology, Published online: 04 June 2026; doi:10.1038/s41587-026-03182-5The significance of the first FDA-approved PROTAC lies not in proving that targeted protein degradation is superior to conventional therapies, but in proving that degrading proteins is possible as a therapeutic.
A socially assistive robot to support mental wellbeing in LGBTQ+ young people at risk of self-harm: a randomized controlled trial
Nature Medicine, Published online: 04 June 2026; doi:10.1038/s41591-026-04422-6A randomized controlled trial integrating Purrble, a socially assistive tactile robot, into safety planning found that LGBTQ+ youth at risk of self-harm experienced improvements in Difficulties in Emotion Regulation Scale and fewer depressive…
AAV gene therapy for homozygous familial hypercholesterolemia: a phase 1 trial
Nature Medicine, Published online: 04 June 2026; doi:10.1038/s41591-026-04441-3After preclinical testing, a phase 1 trial involving three individuals with familial hypercholesterolemia demonstrated preliminary evidence for the safety and efficacy of AAV8-mediated LDL receptor gene therapy.
Spinal cord stimulation for upper limb motor function in people with chronic post-stroke hemiparesis: a feasibility trial
Nature Medicine, Published online: 04 June 2026; doi:10.1038/s41591-026-04435-1In this feasibility clinical trial, the authors show that epidural stimulation of the cervical spinal cord safely improved strength, function and spasticity in seven people with arm hemiparesis.
Human microglial transitions at the Aβ–tau inflection point associate with divergent pathways to dementia and resilience
Nature Medicine, Published online: 04 June 2026; doi:10.1038/s41591-026-04393-8Microglia cellular changes underlie divergent resilience-associated mechanisms in human aging.
Aberrant tau accumulation caused by MAPT mutations induces early pathological changes in axonal transport that are rescued by p38α inhibition
Nature Neuroscience, Published online: 04 June 2026; doi:10.1038/s41593-026-02266-4Imaging axonal transport in vivo in the mouse cortex reveals that deficits in axonal transport arise at early stages of tau pathology, are caused by enlarged tau envelopes and are reversed by inhibiting…
How courts are coping with a flood of AI-generated lawsuits
Most days in her chambers, Judge Maritza Braswell, a federal magistrate judge in Colorado, sifts through stacks of documents written by people without a lawyer. Many of them can’t afford to hire a lawyer, and others have cases too weak…
STAT+: Does Revolution Medicines’ pancreatic cancer drug have even greater potential?
Revolution Medicines' pancreatic cancer drug has not yet been approved — and already talk has shifted to how (and when) its use might be expanded.
What happens at a longevity festival?
What happens at a longevity festival? On this week's STATus Report, Alex Hogan gets a dispatch from STAT's Sarah Todd.
Opinion: Grail’s multi-cancer early detection trial was negative. But as an oncologist, I see more to this story
An oncologist shares three lessons from the world’s first randomized trial on a multi-cancer early detection.
Opinion: Lawmakers promised cancer patients would be protected from Medicaid cuts. Now CMS says otherwise
“One of the cancer community’s worst fears is coming to pass,” writes Gwen Nichols of Blood Cancer United.
STAT+: After hospitals, patients get a turn to bring AI into the doctor’s office
Ambient scribes were the first large-scale application of AI in health care. Now developers are pitching them as diligent note-takers for patients.
Transcranial Temporal Interference Stimulation for Children With Autism Spectrum Disorders
Conditions: Autism Spectrum Disorder Interventions: Device: transcranial Temporal Interference Stimulation Sponsors: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Recruiting
A Positron Emission Tomography (PET) Study to Evaluate Dopamine D2 and D3 Receptor Occupancy by SIPI6398
Conditions: Schizophrenia Disorder Interventions: Drug: SIPI6398 Tablets Sponsors: Shanghai Zhongze Therapeutics Co., Ltd.; Yale University Not yet recruiting
A Prospective Comparative Study Evaluating the Safety and Efficacy of Transurethral Thulium Fiber Laser, Holmium Laser and Bipolar Enucleation of Large Sized Prostate
Conditions: Benign Prostatic Hyperplasia (BPH); Lower Urinary Tract Symptom; Bladder Outlet Obstruction Interventions: Procedure: Endoscopic Enucleation of the Prostate; Procedure: Endoscopic Enucleation of the Prostate; Procedure: Endoscopic Enucleation of the Prostate Sponsors: Tanta University Recruiting