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3090 results

Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial

Conditions: Suicidal Ideation; Suicide Attempt; Safety Plan; Depression / Major Depressive Disorder; Hopelessness Interventions: Behavioral: CAMS Brief Intervention; Behavioral: Stanley-Brown Safety Planning Intervention Sponsors: The Cleveland Clinic Not yet recruiting

Tags: Clinical trial, Depression, Healthcare provider, Mood and emotional regulation

Read more

The Download: Trump’s new AI order, and smart glasses for warfare

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. 5 key points in Trump’s new AI order Less than two weeks after scrapping an executive…

Tags: Biotech, European Union, France, Government / public service

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Transcriptional signatures of the cortical morphometric similarity network gradient in left temporal lobe epilepsy with different seizure symptoms

BackgroundTemporal lobe epilepsy (TLE) manifests with diverse seizure symptoms, including focal to bilateral tonic—clonic seizures (FBTCS), linked to widespread brain network disruptions. The role of cortical morphometric similarity (MS) network gradients and their relationship with gene expression in TLE remains…

Tags: Dissociation and identity integration

Read more

Prediction model for postoperative delirium risk in elderly hypertensive patients: machine learning-based development and validation

BackgroundPostoperative delirium (POD) is a severe complication in elderly hypertensive patients, associated with poor long-term outcomes. Existing models often rely on intraoperative data, limiting preoperative risk stratification. This study aimed to develop a non-invasive machine learning model to predict POD…

Tags: Academic research, Mental health, Sleep and arousal regulation

Read more

Treatment outcomes of an integrated treatment model for patients with co-occurring opioid use and schizophrenia spectrum disorders

BackgroundIndividuals with schizophrenia spectrum disorders are at elevated risk for developing opioid use disorder and often experience higher substance use rates and morbidity. However, integrated treatment models for such patients remain rare.ObjectiveThis study addresses a gap in clinical knowledge by…

Tags: Academic research, Medication, Schizophrenia spectrum, Substance abuse

Read more

Clinical practice guidelines and quality standards for early intervention in psychosis: an AGREE II appraisal and systematic review of service components

BackgroundEarly intervention in psychosis (EIP) is a key component of youth mental health care, yet recommended models of care for individuals at clinical high risk for psychosis (CHR-P) and first-episode psychosis (FEP) remain heterogeneous across jurisdictions. No previous study has…

Tags: Academic research, Medication, Mental health, Reality testing and perceptual stability, Schizophrenia spectrum

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Case Report: Multimodal clinical and neurophysiological effects of cranial electrotherapy stimulation in a patient with chronic stress and sleep disturbance

IntroductionCranial Electrotherapy Stimulation (CES) is a non-invasive brain stimulation (NIBS) technique used for anxiety and sleep disorders; however, case-level evidence linking clinical improvement with objective neurophysiological change remains limited. This case presents a multimodal examination of the therapeutic and neurophysiological…

Tags: Anxiety, Depression, Medication, Mental health, Sleep and arousal regulation

Read more

Reduced serum cortisol, IGF-1, GLP-1, and T3 levels in medication-free children and adolescents with obsessive–compulsive disorder: a case–control study

IntroductionObsessive–compulsive disorder (OCD) frequently emerges during childhood and adolescence and has been associated with alterations in multiple neurobiological systems. Neuroendocrine pathways involved in stress regulation, neurodevelopment, metabolic signaling, and thyroid function interact closely to influence brain circuits implicated in OCD.…

Tags: Academic research, Anxiety, Appetite and ingestive regulation, Fear and threat response, Medication, OCD

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Programmable control of bacterial operons with a single Cas13 RNA effector

Nature Biotechnology, Published online: 03 June 2026; doi:10.1038/s41587-026-03159-4The SONAR system enables RNA-level control of bacterial operons using a single engineered Cas13 effector that can be modified to control transcript degradation, translation inhibition and translation activation through simple changes in crRNA…

Tags: Biotech

Read more

News Feed

News

Disease
Functional Domain
Type
Source
Reset filters

3090 results

Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial

Conditions: Suicidal Ideation; Suicide Attempt; Safety Plan; Depression / Major Depressive Disorder; Hopelessness Interventions: Behavioral: CAMS Brief Intervention; Behavioral: Stanley-Brown Safety Planning Intervention Sponsors: The Cleveland Clinic Not yet recruiting

Tags: Clinical trial, Depression, Healthcare provider, Mood and emotional regulation

Read more

The Download: Trump’s new AI order, and smart glasses for warfare

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. 5 key points in Trump’s new AI order Less than two weeks after scrapping an executive…

Tags: Biotech, European Union, France, Government / public service

Read more

Transcriptional signatures of the cortical morphometric similarity network gradient in left temporal lobe epilepsy with different seizure symptoms

BackgroundTemporal lobe epilepsy (TLE) manifests with diverse seizure symptoms, including focal to bilateral tonic—clonic seizures (FBTCS), linked to widespread brain network disruptions. The role of cortical morphometric similarity (MS) network gradients and their relationship with gene expression in TLE remains…

Tags: Dissociation and identity integration

Read more

Prediction model for postoperative delirium risk in elderly hypertensive patients: machine learning-based development and validation

BackgroundPostoperative delirium (POD) is a severe complication in elderly hypertensive patients, associated with poor long-term outcomes. Existing models often rely on intraoperative data, limiting preoperative risk stratification. This study aimed to develop a non-invasive machine learning model to predict POD…

Tags: Academic research, Mental health, Sleep and arousal regulation

Read more

Treatment outcomes of an integrated treatment model for patients with co-occurring opioid use and schizophrenia spectrum disorders

BackgroundIndividuals with schizophrenia spectrum disorders are at elevated risk for developing opioid use disorder and often experience higher substance use rates and morbidity. However, integrated treatment models for such patients remain rare.ObjectiveThis study addresses a gap in clinical knowledge by…

Tags: Academic research, Medication, Schizophrenia spectrum, Substance abuse

Read more

Clinical practice guidelines and quality standards for early intervention in psychosis: an AGREE II appraisal and systematic review of service components

BackgroundEarly intervention in psychosis (EIP) is a key component of youth mental health care, yet recommended models of care for individuals at clinical high risk for psychosis (CHR-P) and first-episode psychosis (FEP) remain heterogeneous across jurisdictions. No previous study has…

Tags: Academic research, Medication, Mental health, Reality testing and perceptual stability, Schizophrenia spectrum

Read more

Case Report: Multimodal clinical and neurophysiological effects of cranial electrotherapy stimulation in a patient with chronic stress and sleep disturbance

IntroductionCranial Electrotherapy Stimulation (CES) is a non-invasive brain stimulation (NIBS) technique used for anxiety and sleep disorders; however, case-level evidence linking clinical improvement with objective neurophysiological change remains limited. This case presents a multimodal examination of the therapeutic and neurophysiological…

Tags: Anxiety, Depression, Medication, Mental health, Sleep and arousal regulation

Read more

Reduced serum cortisol, IGF-1, GLP-1, and T3 levels in medication-free children and adolescents with obsessive–compulsive disorder: a case–control study

IntroductionObsessive–compulsive disorder (OCD) frequently emerges during childhood and adolescence and has been associated with alterations in multiple neurobiological systems. Neuroendocrine pathways involved in stress regulation, neurodevelopment, metabolic signaling, and thyroid function interact closely to influence brain circuits implicated in OCD.…

Tags: Academic research, Anxiety, Appetite and ingestive regulation, Fear and threat response, Medication, OCD

Read more

Programmable control of bacterial operons with a single Cas13 RNA effector

Nature Biotechnology, Published online: 03 June 2026; doi:10.1038/s41587-026-03159-4The SONAR system enables RNA-level control of bacterial operons using a single engineered Cas13 effector that can be modified to control transcript degradation, translation inhibition and translation activation through simple changes in crRNA…

Tags: Biotech

Read more