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3090 results

Programmable control of bacterial operons with a single Cas13 RNA effector

Nature Biotechnology, Published online: 03 June 2026; doi:10.1038/s41587-026-03159-4The SONAR system enables RNA-level control of bacterial operons using a single engineered Cas13 effector that can be modified to control transcript degradation, translation inhibition and translation activation through simple changes in crRNA…

Tags: Biotech

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Reinventing biotech systems for patient impact

Nature Medicine, Published online: 03 June 2026; doi:10.1038/s41591-026-04445-zChina’s integration of national reforms with institutional redesign has accelerated drug development and access to medicines. As momentum shifts globally, what can other nations learn from this experience?

Tags: Biotech, Medication

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A brainstem pathway underlying vagal modulation of somatic pain and affective states

Nature Neuroscience, Published online: 03 June 2026; doi:10.1038/s41593-026-02313-0This study identifies a brainstem pathway through which vagus nerve stimulation reduces pain and negative affect, showing how the caudal nucleus of the solitary tract transforms pain signals and regulates pain-related dopamine responses.

Tags: Academic research, Fear and threat response, Medication, Mood and emotional regulation

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The representational geometry of emotional states in basolateral amygdala

Nature Neuroscience, Published online: 03 June 2026; doi:10.1038/s41593-026-02315-yO’Neill, Posani and colleagues show that while single amygdala neurons encode multiple emotional state-related variables (for example, valence, fear and safety), population-level geometry can enable one variable to be read out cleanly without…

Tags: Fear and threat response

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Regulating Together for Intellectual Disability: A Group Behavioral Therapy for for Emotion Dysregulation in Autism and Intellectual Disability

Conditions: Autism; Intellectual Disabilities With Other Behavioral Symptoms; Intellectual Disability Interventions: Behavioral: Regulating Together group therapy Sponsors: Children's Mercy Hospital Kansas City; National Institutes of Health (NIH); National Center for Advancing Translational Sciences (NCATS); Frontiers Clinical & Translational Science Institute…

Tags: Autism, BPD, Healthcare provider, Therapy

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Developing a Virtual Reality-assisted Intervention for Emotion Regulation Difficulties in Psychosis

Conditions: Psychosis; SCHIZOPHRENIA 1 (Disorder); Schizophrenia and Related Disorders Interventions: Other: MANOEUVRE therapy Sponsors: King's College London; South London and Maudsley NHS Foundation Trust Not yet recruiting

Tags: Charity / nonprofit, Healthcare provider, Reality testing and perceptual stability, Schizophrenia spectrum, Social and attachment drive, United Kingdom

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NeuroFinance Human Stress Trial During Financial and Informational Volatility

Conditions: Psychological Stress; Anxiety; Emotional Stress; Autonomic Nervous System Dysfunction; Sleep Disturbance; Insomnia; Behavioral Health; Cognitive Fatigue; Occupational Stress; Financial Stress; Burnout Syndrome; Heart Rate Variability; Neurobehavioral Manifestations Interventions: Device: Wearable Physiologic Monitoring Platform Sponsors: Truway Health, Inc. Not yet…

Tags: Anxiety, Medical device, Mental health, Sleep and arousal regulation

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GAIP ASD Research Study

Conditions: Autism Spectrum Disorder; Autism; ASD; Autism Spectrum Disorder (ASD) Interventions: Biological: Umbilical Cord Blood-Derived Stem Cells and Exosomes; Drug: Glutathione Sponsors: Greater Atlanta Integrative Pediatrics Recruiting

Tags: Academic research, Autism

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Effectiveness of a culturally adapted psychoeducational intervention for family caregivers of children with hematologic malignancy: a randomized controlled trial

ObjectiveThis study aimed to develop and evaluate a culturally adapted psychoeducational intervention to address the severe psychological distress and caregiving burden commonly experienced by caregivers of newly diagnosed pediatric hematologic malignancy patients during the early stages of illness.MethodsAmong 116 randomized…

Tags: Academic research, Anxiety, Depression, Psychoeducation program

Read more

News Feed

News

Disease
Functional Domain
Type
Source
Reset filters

3090 results

Programmable control of bacterial operons with a single Cas13 RNA effector

Nature Biotechnology, Published online: 03 June 2026; doi:10.1038/s41587-026-03159-4The SONAR system enables RNA-level control of bacterial operons using a single engineered Cas13 effector that can be modified to control transcript degradation, translation inhibition and translation activation through simple changes in crRNA…

Tags: Biotech

Read more

Reinventing biotech systems for patient impact

Nature Medicine, Published online: 03 June 2026; doi:10.1038/s41591-026-04445-zChina’s integration of national reforms with institutional redesign has accelerated drug development and access to medicines. As momentum shifts globally, what can other nations learn from this experience?

Tags: Biotech, Medication

Read more

A brainstem pathway underlying vagal modulation of somatic pain and affective states

Nature Neuroscience, Published online: 03 June 2026; doi:10.1038/s41593-026-02313-0This study identifies a brainstem pathway through which vagus nerve stimulation reduces pain and negative affect, showing how the caudal nucleus of the solitary tract transforms pain signals and regulates pain-related dopamine responses.

Tags: Academic research, Fear and threat response, Medication, Mood and emotional regulation

Read more

The representational geometry of emotional states in basolateral amygdala

Nature Neuroscience, Published online: 03 June 2026; doi:10.1038/s41593-026-02315-yO’Neill, Posani and colleagues show that while single amygdala neurons encode multiple emotional state-related variables (for example, valence, fear and safety), population-level geometry can enable one variable to be read out cleanly without…

Tags: Fear and threat response

Read more

Regulating Together for Intellectual Disability: A Group Behavioral Therapy for for Emotion Dysregulation in Autism and Intellectual Disability

Conditions: Autism; Intellectual Disabilities With Other Behavioral Symptoms; Intellectual Disability Interventions: Behavioral: Regulating Together group therapy Sponsors: Children's Mercy Hospital Kansas City; National Institutes of Health (NIH); National Center for Advancing Translational Sciences (NCATS); Frontiers Clinical & Translational Science Institute…

Tags: Autism, BPD, Healthcare provider, Therapy

Read more

Developing a Virtual Reality-assisted Intervention for Emotion Regulation Difficulties in Psychosis

Conditions: Psychosis; SCHIZOPHRENIA 1 (Disorder); Schizophrenia and Related Disorders Interventions: Other: MANOEUVRE therapy Sponsors: King's College London; South London and Maudsley NHS Foundation Trust Not yet recruiting

Tags: Charity / nonprofit, Healthcare provider, Reality testing and perceptual stability, Schizophrenia spectrum, Social and attachment drive, United Kingdom

Read more

NeuroFinance Human Stress Trial During Financial and Informational Volatility

Conditions: Psychological Stress; Anxiety; Emotional Stress; Autonomic Nervous System Dysfunction; Sleep Disturbance; Insomnia; Behavioral Health; Cognitive Fatigue; Occupational Stress; Financial Stress; Burnout Syndrome; Heart Rate Variability; Neurobehavioral Manifestations Interventions: Device: Wearable Physiologic Monitoring Platform Sponsors: Truway Health, Inc. Not yet…

Tags: Anxiety, Medical device, Mental health, Sleep and arousal regulation

Read more

GAIP ASD Research Study

Conditions: Autism Spectrum Disorder; Autism; ASD; Autism Spectrum Disorder (ASD) Interventions: Biological: Umbilical Cord Blood-Derived Stem Cells and Exosomes; Drug: Glutathione Sponsors: Greater Atlanta Integrative Pediatrics Recruiting

Tags: Academic research, Autism

Read more

Effectiveness of a culturally adapted psychoeducational intervention for family caregivers of children with hematologic malignancy: a randomized controlled trial

ObjectiveThis study aimed to develop and evaluate a culturally adapted psychoeducational intervention to address the severe psychological distress and caregiving burden commonly experienced by caregivers of newly diagnosed pediatric hematologic malignancy patients during the early stages of illness.MethodsAmong 116 randomized…

Tags: Academic research, Anxiety, Depression, Psychoeducation program

Read more