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Expression of Concern for: Nicotine breaks down preformed Alzheimer’s β-amyloid fibrils in vitro
Expression of Concern for: “Nicotine breaks down preformed Alzheimer’s β-amyloid fibrils in vitro,” by Ono et al. (Biol Psychiatry 2002; 52:880–886); https://doi.org/10.1016/S0006-3223(02)01417-8.
Opinion: The podcast bringing together MAHA and public health for hard conversations
“These sides aren't talking to each other. And there's a lot riding on it”: The hosts of “Why Should I Trust You?” on bringing together MAHA and public health.
Optimism for Trump’s CDC pick is tempered by questions about RFK Jr.’s role
As one CDC employee, who asked not to be named, put it on Friday, among staff “the general vibe is guarded but hopeful.”
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Transcriptomic profiling and targeted validation reveal molecular mechanisms of oxygen therapy in high-altitude cerebral injury
BackgroundExposure to high-altitude hypoxia is associated with an increased risk of impaired brain structure and function, with oxidative stress and neuroinflammation widely recognized as key mechanisms involved. In this context, hyperbaric oxygen therapy is considered a potential intervention; however, the…
How yoga shapes the brain: a systematic review
Yoga is a mind–body practice that originated in India thousands of years ago, and which has extended throughout the world in recent years. As it becomes more popular, more studies are being conducted regarding its health benefits in multiple areas,…
From peripheral initiation to central integration: a narrative review of the antihypertensive mechanisms of acupuncture in regulating autonomic nervous system homeostasis
Essential Hypertension (EH) is one of the most prevalent chronic cardiovascular diseases, imposing a significant burden on healthcare systems worldwide due to its high rates of disability and mortality. Long-term elevation of blood pressure leads to multi-organ damage in the…
Causal network analysis-based assessment of gray matter alteration in post-radiotherapy nasopharyngeal carcinoma patients using 3D T1-weighted MRI
ObjectivesTo explore the temporal and causal relationships underlying brain structural changes in post-radiotherapy (RT) nasopharyngeal carcinoma (NPC) patients.MethodsA total of 38 post-radiotherapy NPC patients (33 males, 5 females; median age: 50.0 years, range: 27–63 years; median time post-RT: 17.2 months,…
A novel behavioral paradigm using mice to study predictive postural control
Postural control circuitry performs the essential function of maintaining balance and body position in response to perturbations that are either self-generated (e.g., reaching to pick up an object) or externally delivered (e.g., being pushed by another person). Human studies have…
The associations of systemic inflammation and insulin resistance-related indicators with psychopathology and BDNF in patients with chronic schizophrenia
BackgroundThe triglyceride-glucose (TyG) index and C-reactive protein-triglyceride-glucose index (CTI) are innovative indicators for assessing insulin resistance (IR) and inflammation, yet research on them in patients with schizophrenia remains limited. This study aimed to explore TyG index and CTI levels and…
ASYM: multimodal depression recognition via mamba-enhanced attentive feature fusion
IntroductionDepression is a prevalent mental disorder with a severe global impact. Traditional interview-based assessments are limited by subjectivity, lengthy procedures, and unequal access to care. Although advances in AI have facilitated multimodal models for depression detection—using audiovisual data as an…
Adverse childhood experiences and the risk of non-suicidal self-injury: a meta-analysis
BackgroundSystematically evaluate the association between Adverse Childhood Experiences (ACEs) and the risk of Non-suicidal Self-Injury (NSSI), thereby providing evidence-based guidance for relevant prevention and early intervention strategies.MethodsA systematic search was conducted across PubMed, Embase, Web of Science, and the Cochrane…
Patient safety incidents in mental health residential services: a multicenter, crosssectional, survey-based study
IntroductionWhile patient safety in general hospitals is well-researched, residential mental health services have received less attention. Psychiatric patients and staff working in such facilities face unique and complex risks. This study aims to explore and describe the frequency and characteristics…
Evaluation of anxiety levels and stress coping methods of pregnant women after the Kahramanmaraş earthquake
ObjectiveNatural disasters can cause serious psychological pressures on women during pregnancy. How the mental health of pregnant women is affected after major disasters such as earthquakes and what coping methods come into play in this process is an important research…
Plasma proteomic signature of the human menstrual cycle
Nature Medicine, Published online: 13 April 2026; doi:10.1038/s41591-026-04326-5This Resource presents a large-scale analysis of nearly 3,000 circulating plasma proteins across the menstrual cycle in over 2,700 women from the UK Biobank, revealing distinct proteomic patterns across menstrual phases. This work…
STAT+: Revolution Medicines touts ‘unprecedented’ data for pancreatic cancer pill
In a trial, metastatic pancreatic cancer patients on the medicine lived twice as long as those on chemotherapy.
STAT+: Allogene Therapeutics’ CAR-T treatment eliminates residual cancer cells in B-cell lymphoma patients
The new data bolster Allogene’s efforts to develop a new, easily administered cell therapy that could delay or prevent cancer recurrence.
STAT+: Spyre Therapeutics IBD drug shows promise in early trial
The inflammatory bowel disease therapy succeeded in its first major testing, setting up a competition with several large drugmakers.
You have no choice in reading this article—maybe
Uri Maoz loved doing his human research, back when he was getting his PhD. He was studying a very specific topic in computational neuroscience: how the brain instructs our arms to move and how our gray matter in turn perceives…
Job titles of the future: Wildlife first responder
Grizzly bears have made such a comeback across eastern Montana that in 2017, the state hired its first-ever prairie-based grizzly manager: wildlife biologist Wesley Sarmento. For some seven years, Sarmento worked to keep both the bears, which are still listed…
Opinion: STAT+: Landmines await Vinay Prasad’s successor at the FDA
Who would want to be the head of the FDA's Center for Biologics Evaluation and Research?
STAT+: Hospitals roll out chatbots, looking to reclaim their role in patients’ health conversations
A handful of hospitals are launching their own chatbots, a risky bet aimed at better serving current patients and gaining new ones.
Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)
Conditions: PTSD; Post Traumatic Stress Disorder PTSD; PTSD - Post Traumatic Stress Disorder; Post Traumatic Stress Disorder; Post Traumatic Stress Disorders; Post-traumatic Stress Disorder (PTSD); Post-Traumatic Stress Disorder, PTSD Interventions: Device: non-invasive vagus nerve stimulation Sponsors: Acacia Clinics; ElectroCore INC;…
AI-Guided Relaxation for Hemodialysis Anxiety
Conditions: Renal Insufficiency, Chronic; Anxiety; Relaxation Therapy; Maintenance Hemodialysis; Stress, Psychological Interventions: Device: AI-Guided Relaxation Platform; Other: Standard Hemodialysis Nursing Care Sponsors: Alexandria University Not yet recruiting