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Disease Detection Gets Boost from Keck’s New Brain Reference Map
A research team used diffusion magnetic resonance imaging (MRI) scans from more than 54,000 people to chart how the brain’s communication pathways develop, mature, and decline across the lifespan. The post Disease Detection Gets…
Mature Intestinal Cells Revert to Stem-Like State to Sustain Colorectal Cancer
The research shows that mature intestinal cells that revert to a stem cell-like state can sustain tumor growth more effectively than mutated intestinal stem cells. The post Mature Intestinal Cells Revert to Stem-Like State…
Use of the Dynamic Systems Development Method to Inform Technology-Assisted Motivational Interviewing (TAMI) for Tobacco Cessation: Qualitative Study
Background: Smoking continues to be a leading cause of preventable morbidity and mortality, and more than 480,000 Americans die annually due to smoking-related illness attributable to smoking and secondhand smoke. More advanced, responsive, and…
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Reading speed, visual deficits, and cerebral white matter integrity in veterans with and without mild traumatic brain injury
IntroductionSince 2001, approximately 17.3% of enlisted personnel have experienced a traumatic brain injury (TBI) according to the United States military. Visual deficits (e.g., convergence insufficiency or pursuit abnormalities) are reported as chronic, persistent symptoms of TBI, which can impact daily…
Synaptic alterations are preceding the axonal loss in optic atrophy of Wolfram syndrome mouse model
BackgroundWolfram syndrome is a rare autosomal recessive disorder characterized by antibody-negative early-onset diabetes mellitus, optic atrophy, sensorineural hearing loss, arginine-vasopressin deficiency, and progressive neurodegeneration of the brainstem and cerebellum. It is caused primarily by pathogenic variants in the WFS1 gene,…
Beyond the auditory: anxiety bridges sleep disturbances and depressive symptoms to tinnitus handicap
BackgroundTinnitus is closely associated with psychological factors including anxiety, depression, and sleep disturbances. However, how these variables interact to influence tinnitus severity remains poorly understood, warranting further exploration.MethodsThis retrospective study analyzed data from 285 patients with tinnitus, utilizing the Tinnitus…
Association between neurodegenerative plasma biomarkers and geriatric depression in older adults with and without clinical dementia in Kinshasa, Democratic Republic of the Congo
IntroductionPrevious Western studies have shown an association between neurodegenerative plasma biomarkers and geriatric depression. However, few studies have examined this relationship in sub-Saharan African countries. This article examines this association in older adults with or without clinical dementia in Kinshasa,…
Does the phubbing scale measure the same construct across sexes? Evidence from a Nigerian sample
IntroductionPhubbing is associated with excessive use of digital technologies, and the Phubbing Scale (PS) is widely used to measure it. The PS may be influenced by cultural variations, so it is advisable to validate it before applying it in a…
Unseen intimate partner violence: regional differences in controlling behaviours
IntroductionControlling behaviour is considered a form of emotional abuse and restricts an individual’s autonomy. This study aims to determine the factors associated with women’s exposure to controlling behaviour by their spouse/partner in the last year, as of the time the…
Remote EMDR versus CBT for PTSD after the Kahramanmaraş earthquakes: a randomized trial
BackgroundLarge-scale earthquakes are associated with high and persistent rates of post-traumatic stress disorder (PTSD), depression, and anxiety. Although Eye Movement Desensitization and Reprocessing (EMDR) and Cognitive Behavioral Therapy (CBT) are both guideline-recommended treatments for PTSD, direct randomized comparisons—particularly in post-disaster…
Naming in medicine: how disease nomenclature shapes diagnosis, research and patient lives
Nature Medicine, Published online: 22 May 2026; doi:10.1038/s41591-026-04456-wNaming in medicine: how disease nomenclature shapes diagnosis, research and patient lives
Semaglutide versus placebo in individuals with poor weight loss after bariatric surgery: a double-blinded, randomized, placebo-controlled trial
Nature Medicine, Published online: 22 May 2026; doi:10.1038/s41591-026-04416-4At week 68, in patients who experienced poor weight loss following bariatric surgery, semaglutide was associated with 18.0% weight loss compared to 0.4% weight gain in patients receiving placebo.
AI-induced never-skilling in medical education
Nature Medicine, Published online: 22 May 2026; doi:10.1038/s41591-026-04438-yWill medical trainees who rely on AI fail to develop foundational independent clinical reasoning? This Perspective outlines a precautionary framework to preserve foundational competence while supporting safe and effective AI integration in medical…
STAT+: Longevity startup Retro Biosciences says latest fundraising values it at $1.8 billion
Retro Biosciences, the longevity startup backed by OpenAI CEO Sam Altman, has raised more money at a $1.8 billion valuation, it announced Friday.
A federal office of men’s health has never been closer, yet it’s likely still years away
Supporters worry that a men’s health office created by the Trump administration risks being dismantled by a future Democratic president
Google I/O showed how the path for AI-driven science is shifting
During Tuesday’s Google I/O keynote, Demis Hassabis, the CEO of Google DeepMind, proclaimed that we are currently “standing in the foothills of the singularity.” It was a striking statement—the singularity is the theoretical future moment when AI rapidly exceeds human…
The Enhanced Games fit right in with the rest of 2026’s longevity vibes
This Sunday, a group of 42 athletes will gather in Las Vegas to compete in a somewhat unusual sporting competition. Participants in the inaugural Enhanced Games are being encouraged to take performance-enhancing drugs. The goal is to “push the boundaries of…
Opinion: The seed oil panic is hurting my cardiac patients
“My patients are replacing olive oil with beef tallow, even if they don't tell me during cardiac rehab,” writes a clinical dietitian.
Opinion: Check-in and intake at the doctor’s office are perfect for AI
This skeptic of AI in medicine sees one place where it could be valuable.
STAT+: Genentech is soliciting research that can be used to blunt pharma reforms in Washington
How a pharma company is soliciting research that can be used to blunt pharma proposed reforms in Washington.
Transcranial Sonography and Machine Learning for Schizophrenia Identification
Conditions: Schizophrenia Interventions: Diagnostic Test: Transcranial Sonography Sponsors: Taizhou Second People's Hospital Not yet recruiting
A Descriptive Study of the Correlation Between Postpartum Depression and Body Image Dissatisfaction, Self-objectification, and Social Media Appearance Comparison
Conditions: Postpartum Depression Sponsors: Sun Yat-sen University Not yet recruiting
Accelerated iTBS for Major Depression
Conditions: Major Depressive Disorder (MDD); Treatment Resistant Depression (TRD) Interventions: Device: Accelerated Intermittent Theta Burst Stimulation (iTBS) Sponsors: Istanbul University - Cerrahpasa Recruiting