News Feed
Single-Cell Analysis Reveals Distinct Biology of Early-Onset Colorectal Cancer
An atlas of more than 850,000 nuclei revealed distinct cellular and genetic features in early-onset colorectal cancer, including changes associated with aggressive tumor behavior and poorer outcomes. The post Single-Cell Analysis Reveals Distinct Biology…
Is the oxytocin system a keystone in human wellbeing?
It has also taken over a century for science to fully realize that oxytocin is far more than a “female reproductive hormone.” Both the measurement and interpretation of the biochemical and functional properties of…
News
3048 results
Synaptic mechanisms for differential severity of social preference deficits in male and female mice induced by diminished activity-dependent BDNF
Males are more commonly diagnosed with autism spectrum disorder (ASD) than females with a ratio of about 4–1. However, the neural mechanisms underlying the sex differences in ASD are unknown. Social deficits are the core symptoms of patients with ASD.…
Resting-state functional connectivity of the sensorimotor network in medication-naïve Chinese children with ADHD: cross-sectional associations with hyperactivity/impulsivity and executive function
BackgroundAttention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder, often—but not always—characterized by inattention, hyperactivity/impulsivity, and deficits in executive functions (EFs); some individuals may also exhibit sensorimotor dysfunction. While SMN dysfunction has been implicated in ADHD, the patterns of SMN functional…
Historical trauma as a contributor to postpartum depression among Indigenous mothers
IntroductionPostpartum depression (PPD) is a significant public health concern. Moreover, research suggests that American Indian/Alaskan Native (AI/AN) mothers experience postpartum depression at higher rates than the general population (Heck, 2021; Ko et al., 2017). As a result, understanding the potential…
Immersive wearable virtual reality for autism: a systematic review of current evidence
IntroductionImmersive and wearable virtual reality (VR) is an emerging technology with growing potential to support assessment and intervention ifor autistic people. The methodological heterogeneity of existing studies limits the interpretation and generalization of current evidence.MethodsA systematic review with a narrative…
Autonomic dysregulation and nonsuicidal self-injury: findings from a cross-sectional online survey
IntroductionDysregulation of the autonomic nervous system has been implicated in nonsuicidal self-injury (NSSI) in laboratory studies of physiological reactivity, but it remains unclear whether self-reported everyday autonomic symptom burden is associated with NSSI severity.MethodsWe conducted a preregistered cross-sectional online survey…
Clinical warning signs preceding severe suicide attempts requiring pediatric intensive care in children and adolescents
BackgroundChildhood suicide attempts requiring pediatric intensive care unit (PICU) admission represent some of the most severe forms of self-harm and are associated with substantial morbidity and mortality. This study aimed to identify potential psychosocial factors and clinical warning signs preceding…
Engineered polyketide synthases enable a microbial chassis for recyclable plastics with tunable properties
Nature Biotechnology, Published online: 27 July 2026; doi:10.1038/s41587-026-03229-7Polyketide synthases are engineered for the production of sustainable plastics.
Toward a test of medical AI superintelligence
Nature Medicine, Published online: 27 July 2026; doi:10.1038/s41591-026-04539-8Researchers urgently need a rigorous, task-based framework to define and measure medical AI ‘superintelligence’, because existing benchmarks are misleading and insufficient.
Longitudinal plasma proteomics predict phenoconversion to clinically manifest ALS
Nature Medicine, Published online: 27 July 2026; doi:10.1038/s41591-026-04528-xLongitudinal proteomic analysis of plasma from unaffected carriers of ALS-associated pathogenic variants revealed early protein changes before ALS symptoms and enabled mapping of their trajectories as well as prediction of the timing of…
A trend that isn’t fading, ultra-processed baby foods
An FDA advisory panel serves some peptide wins, a measles record, and more health news from Morning Rounds
The Download: lasers for nuclear fuel, and organ preservation advances
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. How lasers could help provide fuel for nuclear reactors Nuclear power provides about 9% of global…
The path to artificial superintelligence
Imagine a healthcare system made up of multiple AI agents: one that manages symptom assessment, another scheduling, a third insurance, and a fourth pharmacy. Each is an expert in its domain. But they all have their own distinct knowledge and…
STAT+: RA Capital backs upstart rival to Ultragenyx and Ionis in rare brain disease
Oak Hill Bio, a new company backed by RA Capital and other investors, will take on Ultragenyx and Ionis in developing an Angelman syndrome medicine.
Closing the data loop in AI-driven drug discovery
Drug discovery is a high-cost, high-risk endeavor that is under growing pressure from a market increasingly defined by first-mover advantage. Since the 1950s, the cost of developing new pharmaceuticals has roughly doubled every nine years—a phenomenon known as Eroom’s Law.…
Building the enterprise environment for agentic AI
For the enterprise, the promise of agentic AI is much more than just a better chatbot. It is software agents that execute business tasks end-to-end across people, business workflows, data, and systems. The platform best-suited to run agents is built…
Opinion: How midwives like me can help fight medical misinformation
“I have come to believe that changing a mind is rarely the point. Planting a seed is,” writes nurse-midwife Mara Evans.
STAT+: As some medical schools embrace RFK Jr.’s nutrition push, they deftly sidestep MAHA priorities
Even as some medical schools heed health secretary Robert F. Kennedy Jr.’s call for more nutrition education, several told STAT that they plan to steer clear of topics that aren’t…
Opinion: E-bikes, e-scooters are a burgeoning pediatric public health emergency
“Emergency departments across America report dramatic increases in serious injuries from e-bikes and e-scooters,” write CHOP’s J. Todd R. Lawrence and Madison A. Kesler.
Clinical Trial of “Exploradores de Sabores” to Improve Food Selectivity in ASD Kids
Conditions: Autism Spectrum Disorder; Food Selectivity Interventions: Behavioral: Exploradores de Sabores Parent-Mediated Nutrition Intervention; Other: Education as Usual (EAU) Sponsors: Universidad Autonoma de Baja California Recruiting
SONATA LIFU for OCD
Conditions: Obsessive Compulsive Disorder Interventions: Device: Low Intensity Focused Ultrasound; Device: Sham (No Treatment) Sponsors: University of Pennsylvania; Attune Neurosciences Inc Recruiting
News Feed
Single-Cell Analysis Reveals Distinct Biology of Early-Onset Colorectal Cancer
An atlas of more than 850,000 nuclei revealed distinct cellular and genetic features in early-onset colorectal cancer, including changes associated with aggressive tumor behavior and poorer outcomes. The post Single-Cell Analysis Reveals Distinct Biology…
Is the oxytocin system a keystone in human wellbeing?
It has also taken over a century for science to fully realize that oxytocin is far more than a “female reproductive hormone.” Both the measurement and interpretation of the biochemical and functional properties of…
News
3048 results
Synaptic mechanisms for differential severity of social preference deficits in male and female mice induced by diminished activity-dependent BDNF
Males are more commonly diagnosed with autism spectrum disorder (ASD) than females with a ratio of about 4–1. However, the neural mechanisms underlying the sex differences in ASD are unknown. Social deficits are the core symptoms of patients with ASD.…
Resting-state functional connectivity of the sensorimotor network in medication-naïve Chinese children with ADHD: cross-sectional associations with hyperactivity/impulsivity and executive function
BackgroundAttention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder, often—but not always—characterized by inattention, hyperactivity/impulsivity, and deficits in executive functions (EFs); some individuals may also exhibit sensorimotor dysfunction. While SMN dysfunction has been implicated in ADHD, the patterns of SMN functional…
Historical trauma as a contributor to postpartum depression among Indigenous mothers
IntroductionPostpartum depression (PPD) is a significant public health concern. Moreover, research suggests that American Indian/Alaskan Native (AI/AN) mothers experience postpartum depression at higher rates than the general population (Heck, 2021; Ko et al., 2017). As a result, understanding the potential…
Immersive wearable virtual reality for autism: a systematic review of current evidence
IntroductionImmersive and wearable virtual reality (VR) is an emerging technology with growing potential to support assessment and intervention ifor autistic people. The methodological heterogeneity of existing studies limits the interpretation and generalization of current evidence.MethodsA systematic review with a narrative…
Autonomic dysregulation and nonsuicidal self-injury: findings from a cross-sectional online survey
IntroductionDysregulation of the autonomic nervous system has been implicated in nonsuicidal self-injury (NSSI) in laboratory studies of physiological reactivity, but it remains unclear whether self-reported everyday autonomic symptom burden is associated with NSSI severity.MethodsWe conducted a preregistered cross-sectional online survey…
Clinical warning signs preceding severe suicide attempts requiring pediatric intensive care in children and adolescents
BackgroundChildhood suicide attempts requiring pediatric intensive care unit (PICU) admission represent some of the most severe forms of self-harm and are associated with substantial morbidity and mortality. This study aimed to identify potential psychosocial factors and clinical warning signs preceding…
Engineered polyketide synthases enable a microbial chassis for recyclable plastics with tunable properties
Nature Biotechnology, Published online: 27 July 2026; doi:10.1038/s41587-026-03229-7Polyketide synthases are engineered for the production of sustainable plastics.
Toward a test of medical AI superintelligence
Nature Medicine, Published online: 27 July 2026; doi:10.1038/s41591-026-04539-8Researchers urgently need a rigorous, task-based framework to define and measure medical AI ‘superintelligence’, because existing benchmarks are misleading and insufficient.
Longitudinal plasma proteomics predict phenoconversion to clinically manifest ALS
Nature Medicine, Published online: 27 July 2026; doi:10.1038/s41591-026-04528-xLongitudinal proteomic analysis of plasma from unaffected carriers of ALS-associated pathogenic variants revealed early protein changes before ALS symptoms and enabled mapping of their trajectories as well as prediction of the timing of…
A trend that isn’t fading, ultra-processed baby foods
An FDA advisory panel serves some peptide wins, a measles record, and more health news from Morning Rounds
The Download: lasers for nuclear fuel, and organ preservation advances
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. How lasers could help provide fuel for nuclear reactors Nuclear power provides about 9% of global…
The path to artificial superintelligence
Imagine a healthcare system made up of multiple AI agents: one that manages symptom assessment, another scheduling, a third insurance, and a fourth pharmacy. Each is an expert in its domain. But they all have their own distinct knowledge and…
STAT+: RA Capital backs upstart rival to Ultragenyx and Ionis in rare brain disease
Oak Hill Bio, a new company backed by RA Capital and other investors, will take on Ultragenyx and Ionis in developing an Angelman syndrome medicine.
Closing the data loop in AI-driven drug discovery
Drug discovery is a high-cost, high-risk endeavor that is under growing pressure from a market increasingly defined by first-mover advantage. Since the 1950s, the cost of developing new pharmaceuticals has roughly doubled every nine years—a phenomenon known as Eroom’s Law.…
Building the enterprise environment for agentic AI
For the enterprise, the promise of agentic AI is much more than just a better chatbot. It is software agents that execute business tasks end-to-end across people, business workflows, data, and systems. The platform best-suited to run agents is built…
Opinion: How midwives like me can help fight medical misinformation
“I have come to believe that changing a mind is rarely the point. Planting a seed is,” writes nurse-midwife Mara Evans.
STAT+: As some medical schools embrace RFK Jr.’s nutrition push, they deftly sidestep MAHA priorities
Even as some medical schools heed health secretary Robert F. Kennedy Jr.’s call for more nutrition education, several told STAT that they plan to steer clear of topics that aren’t…
Opinion: E-bikes, e-scooters are a burgeoning pediatric public health emergency
“Emergency departments across America report dramatic increases in serious injuries from e-bikes and e-scooters,” write CHOP’s J. Todd R. Lawrence and Madison A. Kesler.
Clinical Trial of “Exploradores de Sabores” to Improve Food Selectivity in ASD Kids
Conditions: Autism Spectrum Disorder; Food Selectivity Interventions: Behavioral: Exploradores de Sabores Parent-Mediated Nutrition Intervention; Other: Education as Usual (EAU) Sponsors: Universidad Autonoma de Baja California Recruiting
SONATA LIFU for OCD
Conditions: Obsessive Compulsive Disorder Interventions: Device: Low Intensity Focused Ultrasound; Device: Sham (No Treatment) Sponsors: University of Pennsylvania; Attune Neurosciences Inc Recruiting