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Case Report: Probable paroxysmal sympathetic hyperactivity during vascular and postoperative critical illness with bilateral white matter abnormalities
BackgroundRecognition of paroxysmal sympathetic hyperactivity (PSH) during vascular and postoperative critical illness is complicated by overlapping infection and seizure features.Case presentationA 37-year-old man developed encephalopathy and rigidity after extensive arterial thrombosis, thrombectomy, and suspected…
Single-cell dataset of juvenile mouse neurons from the thalamic reticular nucleus: whole-cell patch-clamp electrophysiology
This dataset provides single-cell whole-cell patch-clamp electrophysiology for 19 interneurons of the thalamic reticular nucleus (TRN) in juvenile mice. The recordings were obtained from male C57Bl/6J mice sampled within the developmental window of postnatal…
A systematic review and meta-analysis of quantitative pain outcomes in degenerative thoracic myelopathy
IntroductionDegenerative thoracic myelopathy (DTM) refers to symptomatic compression of the thoracic spinal cord secondary to degenerative pathology, including thoracic disc herniation (TDH), ossification of the ligamentum flavum (OLF) and ossification of the posterior longitudinal…
News
3067 results
Feasibility of a Culturally Adapted Nurse-Led COPE Intervention for Caregivers of Children With Autism Spectrum Disorder
Conditions: Autism Spectrum Disorder; Psychological Distress; Depression; Anxiety Interventions: Behavioral: Culturally Adapted Nurse-Led COPE Intervention; Other: Routine Hospital Care Sponsors: Khyber Medical University Peshawar; Children Hospital Faisalabad Recruiting
A Study to Investigate Pharmacokinetics, Safety, and Tolerability of B2227 Extended-Release Injectable Suspension and Vraylar® in Participants With Schizophrenia
Conditions: Schizophrenia Interventions: Drug: 30 mg B2227; Drug: 70 mg B2227; Drug: 150 mg B2227; Drug: Vraylar® 1.5 mg; Drug: Vraylar® 3.0 mg; Drug: Vraylar® 4.5 mg; Drug: Vraylar® 6.0 mg Sponsors: Bostal Drug Delivery Co., Ltd Not yet recruiting
Applying Mixed Methods to Identify Links Between PTSD Symptoms, Cannabis Use, and Functional Behaviors With Personalized Feedback Intervention Development
Conditions: Stress Disorders, Post-Traumatic; Marijuana Abuse Interventions: Behavioral: Personalized Feedback Session (PFS) Sponsors: VA Office of Research and Development Not yet recruiting
A spatial view of tumor neoantigen recognition
Nature Biotechnology, Published online: 22 July 2026; doi:10.1038/s41587-026-03203-3The cell-by-cell interactions between neoantigen-expressing tumor cells and tumor-specific T cells remained largely unexplored. A single-cell spatial transcriptomics framework enables mapping of neoantigen-expressing tumor cells and tumor-infiltrating T cells, as well as T…
Single-nucleus multimodal spatial transcriptomics reveals spatial colocalization of neoantigen-expressing tumor cells and cognate T cells
Nature Biotechnology, Published online: 22 July 2026; doi:10.1038/s41587-026-03194-1Spatial relationships between tumor neoantigens and cognate T cells are studied.
Author Correction: Multi-antigen-targeting T cells in pediatric central nervous system tumors: a phase 1 trial
Nature Medicine, Published online: 22 July 2026; doi:10.1038/s41591-026-04593-2Author Correction: Multi-antigen-targeting T cells in pediatric central nervous system tumors: a phase 1 trial
STAT+: What is a ‘world model’? Nabla’s Alex LeBrun explains
In this edition of AI Prognosis, Brittany Trang talks to Alex LeBrun, AI scribe company Nabla's executive chairman, about an alternative to LLMs
New study supports testing of Merck’s Ebola vaccine in DRC outbreak
New data supports the idea that Merck’s Ebola vaccine Ervebo, licensed to target the Zaire species of ebolaviruses, could also offer some protection against another.
Opinion: What Argentina’s World Cup loss should teach American hospitals
“Hospitals often make Argentina’s mistake: We confuse continuity with progress,” writes physician, hospital administrator, and bioethicist Basel Tarab.
Congo’s Ebola outbreak has killed over 1,000 people
At least 999 people have died from the Ebola outbreak in Congo, a grim toll in what’s already been declared the fastest Ebola outbreak in history.
STAT+: Pharma tries to tamp down broad China restrictions
AI-focused VC firm raises $800M, Merck's new cholesterol pill, and more biotech news from The Readout
Child Mind Institute Launches Research Initiative To Inform Safer AI Systems for Youth
Today, the Child Mind Institute announced a new research initiative, launched with support from the OpenAI Foundation, to build the research infrastructure needed to measure and better understand youth mental health while using AI chatbots and over time. The post…
The Download: NASA’s new space telescope and OpenAI’s autonomous hacker
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Shape-shifting mirrors on NASA’s new space telescope could unveil Jupiters like our own When NASA’s Nancy…
Integration of imaging and clinical biomarkers for cerebral infarction diagnosis via NeuroFusionNet
BackgroundCerebral infarction remains a leading cause of mortality and long-term disability worldwide, demanding rapid and accurate diagnostic strategies. However, current assessments primarily rely on imaging interpretation, often neglecting valuable clinical and laboratory information that could enhance diagnostic precision.MethodsWe developed NeuroFusionNet,…
High-altitude hypoxia alters the developmental trajectory of working memory in Tibetan children
BackgroundVerbal working memory (WM) undergoes rapid development during school age, yet the impact of high-altitude hypoxia on this trajectory remains unclear. We propose two distinct models: the simple additive model, which posits that hypoxia imposes a uniform impairment independent of…
Integration of laryngeal and cardiorespiratory control by the dorsomedial and perifornical hypothalamus in anaesthetised rats
The dorsomedial hypothalamic nucleus and perifornical area (DMH/PeF), historically identified as the hypothalamic defence area, plays a key role in orchestrating autonomic and respiratory adjustments during threat-related states. To investigate how activation of this region affects upper-airway and respiratory motor…
Safety of transcutaneous electrical stimulation potentiating recovery in acute spinal cord injury syndromes: a trial protocol
Background and objectivesSpinal cord injury (SCI) often results in permanent paralysis, leading to substantial long-term disability and loss of quality-adjusted life years. Strategies to preserve neural function in the hyperacute phase are needed. Transcutaneous spinal cord stimulation (tSCS) improves neurological…
Using cortical auditory-evoked potential responses to verify the objective benefit of aural rehabilitation in adult cochlear implant users
IntroductionCortical auditory-evoked potential (CAEP) responses are used clinically to assess auditory processing and support cochlear implant (CI) mapping procedures post-implantation. This study aims to examine CAEP responses as an objective measure of neurophysiological changes following a structured Aural Rehabilitation Program…
Mechanisms underlying the association between perceived recurrence risk and negative emotions in patients with ischemic stroke: a cross-sectional study
ObjectiveTo examine the relationships among perceived risk of recurrence, attitudes toward seeking professional psychological help, negative emotions, and family care in patients with ischemic stroke, and to test a moderated mediation model. The findings aim to provide a scientific basis…
Effects of visual art therapy on depressive symptoms in adults: a systematic review and meta-analysis
ObjectiveTo systematically evaluate the intervention effects of visual art therapy on depressive symptoms in adults, and to examine its impact on anxiety symptoms.MethodsA systematic search was conducted in databases including CNKI, WanFang Data, VIP, Chinese Biomedical Literature Database (CBM), PubMed,…
News Feed
Case Report: Probable paroxysmal sympathetic hyperactivity during vascular and postoperative critical illness with bilateral white matter abnormalities
BackgroundRecognition of paroxysmal sympathetic hyperactivity (PSH) during vascular and postoperative critical illness is complicated by overlapping infection and seizure features.Case presentationA 37-year-old man developed encephalopathy and rigidity after extensive arterial thrombosis, thrombectomy, and suspected…
Single-cell dataset of juvenile mouse neurons from the thalamic reticular nucleus: whole-cell patch-clamp electrophysiology
This dataset provides single-cell whole-cell patch-clamp electrophysiology for 19 interneurons of the thalamic reticular nucleus (TRN) in juvenile mice. The recordings were obtained from male C57Bl/6J mice sampled within the developmental window of postnatal…
A systematic review and meta-analysis of quantitative pain outcomes in degenerative thoracic myelopathy
IntroductionDegenerative thoracic myelopathy (DTM) refers to symptomatic compression of the thoracic spinal cord secondary to degenerative pathology, including thoracic disc herniation (TDH), ossification of the ligamentum flavum (OLF) and ossification of the posterior longitudinal…
News
3067 results
Feasibility of a Culturally Adapted Nurse-Led COPE Intervention for Caregivers of Children With Autism Spectrum Disorder
Conditions: Autism Spectrum Disorder; Psychological Distress; Depression; Anxiety Interventions: Behavioral: Culturally Adapted Nurse-Led COPE Intervention; Other: Routine Hospital Care Sponsors: Khyber Medical University Peshawar; Children Hospital Faisalabad Recruiting
A Study to Investigate Pharmacokinetics, Safety, and Tolerability of B2227 Extended-Release Injectable Suspension and Vraylar® in Participants With Schizophrenia
Conditions: Schizophrenia Interventions: Drug: 30 mg B2227; Drug: 70 mg B2227; Drug: 150 mg B2227; Drug: Vraylar® 1.5 mg; Drug: Vraylar® 3.0 mg; Drug: Vraylar® 4.5 mg; Drug: Vraylar® 6.0 mg Sponsors: Bostal Drug Delivery Co., Ltd Not yet recruiting
Applying Mixed Methods to Identify Links Between PTSD Symptoms, Cannabis Use, and Functional Behaviors With Personalized Feedback Intervention Development
Conditions: Stress Disorders, Post-Traumatic; Marijuana Abuse Interventions: Behavioral: Personalized Feedback Session (PFS) Sponsors: VA Office of Research and Development Not yet recruiting
A spatial view of tumor neoantigen recognition
Nature Biotechnology, Published online: 22 July 2026; doi:10.1038/s41587-026-03203-3The cell-by-cell interactions between neoantigen-expressing tumor cells and tumor-specific T cells remained largely unexplored. A single-cell spatial transcriptomics framework enables mapping of neoantigen-expressing tumor cells and tumor-infiltrating T cells, as well as T…
Single-nucleus multimodal spatial transcriptomics reveals spatial colocalization of neoantigen-expressing tumor cells and cognate T cells
Nature Biotechnology, Published online: 22 July 2026; doi:10.1038/s41587-026-03194-1Spatial relationships between tumor neoantigens and cognate T cells are studied.
Author Correction: Multi-antigen-targeting T cells in pediatric central nervous system tumors: a phase 1 trial
Nature Medicine, Published online: 22 July 2026; doi:10.1038/s41591-026-04593-2Author Correction: Multi-antigen-targeting T cells in pediatric central nervous system tumors: a phase 1 trial
STAT+: What is a ‘world model’? Nabla’s Alex LeBrun explains
In this edition of AI Prognosis, Brittany Trang talks to Alex LeBrun, AI scribe company Nabla's executive chairman, about an alternative to LLMs
New study supports testing of Merck’s Ebola vaccine in DRC outbreak
New data supports the idea that Merck’s Ebola vaccine Ervebo, licensed to target the Zaire species of ebolaviruses, could also offer some protection against another.
Opinion: What Argentina’s World Cup loss should teach American hospitals
“Hospitals often make Argentina’s mistake: We confuse continuity with progress,” writes physician, hospital administrator, and bioethicist Basel Tarab.
Congo’s Ebola outbreak has killed over 1,000 people
At least 999 people have died from the Ebola outbreak in Congo, a grim toll in what’s already been declared the fastest Ebola outbreak in history.
STAT+: Pharma tries to tamp down broad China restrictions
AI-focused VC firm raises $800M, Merck's new cholesterol pill, and more biotech news from The Readout
Child Mind Institute Launches Research Initiative To Inform Safer AI Systems for Youth
Today, the Child Mind Institute announced a new research initiative, launched with support from the OpenAI Foundation, to build the research infrastructure needed to measure and better understand youth mental health while using AI chatbots and over time. The post…
The Download: NASA’s new space telescope and OpenAI’s autonomous hacker
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Shape-shifting mirrors on NASA’s new space telescope could unveil Jupiters like our own When NASA’s Nancy…
Integration of imaging and clinical biomarkers for cerebral infarction diagnosis via NeuroFusionNet
BackgroundCerebral infarction remains a leading cause of mortality and long-term disability worldwide, demanding rapid and accurate diagnostic strategies. However, current assessments primarily rely on imaging interpretation, often neglecting valuable clinical and laboratory information that could enhance diagnostic precision.MethodsWe developed NeuroFusionNet,…
High-altitude hypoxia alters the developmental trajectory of working memory in Tibetan children
BackgroundVerbal working memory (WM) undergoes rapid development during school age, yet the impact of high-altitude hypoxia on this trajectory remains unclear. We propose two distinct models: the simple additive model, which posits that hypoxia imposes a uniform impairment independent of…
Integration of laryngeal and cardiorespiratory control by the dorsomedial and perifornical hypothalamus in anaesthetised rats
The dorsomedial hypothalamic nucleus and perifornical area (DMH/PeF), historically identified as the hypothalamic defence area, plays a key role in orchestrating autonomic and respiratory adjustments during threat-related states. To investigate how activation of this region affects upper-airway and respiratory motor…
Safety of transcutaneous electrical stimulation potentiating recovery in acute spinal cord injury syndromes: a trial protocol
Background and objectivesSpinal cord injury (SCI) often results in permanent paralysis, leading to substantial long-term disability and loss of quality-adjusted life years. Strategies to preserve neural function in the hyperacute phase are needed. Transcutaneous spinal cord stimulation (tSCS) improves neurological…
Using cortical auditory-evoked potential responses to verify the objective benefit of aural rehabilitation in adult cochlear implant users
IntroductionCortical auditory-evoked potential (CAEP) responses are used clinically to assess auditory processing and support cochlear implant (CI) mapping procedures post-implantation. This study aims to examine CAEP responses as an objective measure of neurophysiological changes following a structured Aural Rehabilitation Program…
Mechanisms underlying the association between perceived recurrence risk and negative emotions in patients with ischemic stroke: a cross-sectional study
ObjectiveTo examine the relationships among perceived risk of recurrence, attitudes toward seeking professional psychological help, negative emotions, and family care in patients with ischemic stroke, and to test a moderated mediation model. The findings aim to provide a scientific basis…
Effects of visual art therapy on depressive symptoms in adults: a systematic review and meta-analysis
ObjectiveTo systematically evaluate the intervention effects of visual art therapy on depressive symptoms in adults, and to examine its impact on anxiety symptoms.MethodsA systematic search was conducted in databases including CNKI, WanFang Data, VIP, Chinese Biomedical Literature Database (CBM), PubMed,…