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Lifestyle, psychological and demographic predictors of anxiety: insights from a large-scale survey and machine learning analysis
ObjectiveAnxiety is influenced by a combination of lifestyle, psychological, and demographic factors. This study aimed to evaluate these associations and explore the potential of machine learning in predicting anxiety severity.MethodsAnxiety levels were evaluated using a large survey-based dataset of 11,…
Seasonal and gender-specific patterns in prescriptions for hypnotic and sedative medications in primary care
IntroductionPopulation-level prevalence of sleep disorders can be assessed using prescription data for hypnotic and sedative medications. Such prescribing patterns exhibit seasonality that may be linked to variations in daylight exposure. The aim of this study was to analyze temporal trends…
HPV vaccines, 20 years on
Nature Medicine, Published online: 20 May 2026; doi:10.1038/s41591-026-04374-xWomen are now at the very center of the global cancer control agenda, but there are major challenges ahead.
Aspects of Quality of Life in Interstitial Lung Disease: Pilot Observational Cross-Sectional Study in a Single Center
Background: Quality of life (QOL) is an important aspect of every chronic disease, including interstitial lung disease (ILD). QOL is perceived as a significant patient-centered outcome. Objective: This study aims to identify factors correlating with different aspects of QOL in…
Feasibility of Videoconference-Based Cognitive Behavioral Therapy for Somatic Symptom Disorder: Single-Arm Pilot Trial
Background: Somatic symptom disorder (SSD) is a mental disorder marked by persistent somatic symptoms and maladaptive health-related thoughts, feelings, or behaviors. Cognitive behavioral therapy has been shown to be effective in treating SSD, reducing patients’ somatic symptoms, depressive symptoms, and…
Impact of Restriction-Resumption Protocols on Mood and Anxiety in Healthy Adults: Randomized Controlled Trial
Background: Simple behavioral and cognitive actions can reduce symptoms of anxiety and depression. However, there is limited research investigating whether restricting those same actions increases symptoms and whether resuming those actions reduces symptoms. Objective: The primary aim was to examine…
Development, Feasibility, Acceptability, and Usability of an Artificial Intelligence–Powered Chatbot (Suzy) to Support Patients in Substance Use Disorder Recovery: Multiphase Study
Background: Substance use disorder (SUD) remains a major public health crisis in the United States, with significant challenges in treatment access, retention, and workforce capacity. SUD care teams, including addiction medicine physicians and peer recovery coaches (PRCs), support patients receiving…
Efficacy of a World Health Organization–Guided Self-Help Intervention for Reducing Psychological Distress in Afghan Refugees: Randomized Controlled Trial
Background: Common mental health disorders are highly prevalent among refugees. There is an urgent need to address the mental health burden in this population. Objective: This study tested the efficacy of an individually supported self-help stress-management intervention developed by the…
Congressional Democrats try to force a vote to end Medicare AI prior authorization pilot
Congressional Democrats are mounting a fresh effort to end a Medicare experiment to use AI to approve or deny care.
STAT+: Pioneering trial for treating genetic disease before birth nears reality
A UCSF team has submitted an application to the FDA seeking approval for a small trial of in utero gene therapy for a rare lysosomal storage disorder.
Surgeon general’s office issues warning on screen time for children
A public health advisory calls on parents, schools, and government to limit children's use of screens, saying some patterns of use “can pose real harm to children.”
STAT+: Florida hospitals win $8 billion in extra Medicaid funds
Stricter limits on extra Medicaid funds are coming, stemming from President Trump's tax cut bill.
STAT+: Scientists track cellular disruptions that lead to type 1 diabetes
Growing evidence suggests it takes a sustained viral infection in the right genetic environment to lead to type 1 diabetes.
Green steel startup Boston Metal is doubling down on critical metals
The startup Boston Metal has raised a $75 million funding round to produce critical metals, MIT Technology Review can exclusively report. The company has been known largely for its efforts to clean up steel production, an industry that’s responsible for…
The Download: fully artificial chicken eggs and why Musk lost
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Colossal Biosciences is growing chickens in a 3D-printed artificial eggshell The baby chicks were shifting and…
Machine learning-based morphological brain analysis in schizophrenia and unaffected siblings: a multisite study of potential risk markers
Background and hypothesisAssessing schizophrenia risk factors is crucial for developing early preventive interventions. We hypothesized that unaffected siblings, who share high genetic risk, exhibit neuroanatomical signatures similar to affected patients, potentially reflecting early pathogenic processes.Study designTo overcome single-center limitations, we…
Infant traumatic brain injury with a biphasic clinical course and late diffusion restriction: a case report
Traumatic brain injury (TBI) in young children can rarely exhibit a biphasic clinical course with delayed neurological deterioration. We report a 2-year-old boy who fell from 50 cm and briefly lost consciousness with vomiting, initially found to have a right frontotemporoparietal…