News Feed
Case Report: Probable paroxysmal sympathetic hyperactivity during vascular and postoperative critical illness with bilateral white matter abnormalities
BackgroundRecognition of paroxysmal sympathetic hyperactivity (PSH) during vascular and postoperative critical illness is complicated by overlapping infection and seizure features.Case presentationA 37-year-old man developed encephalopathy and rigidity after extensive arterial thrombosis, thrombectomy, and suspected…
Single-cell dataset of juvenile mouse neurons from the thalamic reticular nucleus: whole-cell patch-clamp electrophysiology
This dataset provides single-cell whole-cell patch-clamp electrophysiology for 19 interneurons of the thalamic reticular nucleus (TRN) in juvenile mice. The recordings were obtained from male C57Bl/6J mice sampled within the developmental window of postnatal…
A systematic review and meta-analysis of quantitative pain outcomes in degenerative thoracic myelopathy
IntroductionDegenerative thoracic myelopathy (DTM) refers to symptomatic compression of the thoracic spinal cord secondary to degenerative pathology, including thoracic disc herniation (TDH), ossification of the ligamentum flavum (OLF) and ossification of the posterior longitudinal…
News
3067 results
Developing a Text Messaging Intervention to Increase Uptake of the Screening and Treatment for Anxiety and Depression Program Among Community College Students: Formative Study Using a Human-Centered Design Approach
Background: Community college (CC) students face significant mental health concerns but are unlikely to receive treatment. Barriers to mental health service uptake among CC students have been delineated, but few studies have identified strategies to improve uptake. Text messaging has…
Optimizing Treatment Strategies in the Bipolar Disorder Spectrum With Classical AI Approaches: Systematic Review of Performance, Bias, and Clinical Applicability
Background: Bipolar disorder (BD) is a complex and heterogeneous psychiatric condition, characterized by fluctuating clinical courses that affect approximately 1%‐2% of the global population in their lifetime. Despite pharmacological advances, treatment response varies significantly among patients, making the identification of…
Opinion: Pete Hegseth, ‘The Odyssey,’ and the testosterone myth
The poet didn’t say “sing to me, Muse, of a man with optimized endocrine panels," writes urologist Elizabeth Dray.
STAT+: Advocates say federal funding is being cut from groups fighting HIV
The administration is shifting some funding to states, but community groups are set to lose out.
Digital Reassurance Seeking in OCD
– by Jordan Karr, PhD We all need reassurance once in a while. Receiving reassurance from a friend, loved one, or expert can reduce short-term distress, foster a sense of connection,... Read more » The post Digital Reassurance Seeking in OCD…
Is there an exodus underway at Epic?
In this edition of STAT Health Tech: executive departures at Epic Systems, new CEO takes over at Nabla, and more health tech news.
The Download: Chinese AI divides the White House, and a record copyright payout
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. China’s AI models have Trump’s AI world at war with itself Last weekend, several current and…
Curcumin attenuates α-synuclein pathology in Parkinson’s disease model mice through modulation of UBC9-associated SUMOylation signaling
BackgroundPost-translational modifications, particularly SUMOylation, plays a crucial role in α-synuclein (α-syn) aggregation, a key pathological feature of Parkinson’s disease (PD). Curcumin, a natural polyphenol, has shown neuroprotective potential, but its effects on SUMOylation-related signaling in PD remain unclear.ObjectiveThis study aimed…
Targeting mitochondria for the treatment of neurodegenerative diseases
Mitochondria are central regulators of cellular metabolism, redox balance, calcium signaling, and cell survival, making them essential for neuronal function. Because neurons rely heavily on mitochondrial oxidative phosphorylation to meet their high energetic demands, mitochondrial dysfunction has emerged as a…
Venous-significant intracranial hemorrhage in neonatal HIE treated with therapeutic hypothermia: imaging phenotypes, diagnostic pitfalls, and prognostic implications
In the therapeutic hypothermia era, intracranial hemorrhage is increasingly detected in term and near-term neonates with hypoxic–ischemic encephalopathy (HIE), yet its clinical significance remains heterogeneous and is often oversimplified. This review uses a pattern-based approach for venous system–related intracranial hemorrhage…
Subcortical gray matter atrophy and iron deposition in patients with vascular dementia: a multimodal MRI study
PurposeVascular dementia (VAD) is the second most common type of dementia worldwide. Therefore, early detection and diagnosis, along with a clear understanding of its pathogenesis are critical for mitigating disease progression. In the present study, we aimed to elucidate the…
Latest developments in the use of e-cigarettes by people with schizophrenia spectrum disorders who smoke: a scoping review
BackgroundTobacco use is significantly more prevalent among individuals with schizophrenia spectrum disorders (SSD) compared to the general population, contributing to elevated rates of premature mortality from smoking-related diseases. Despite a decline in smoking prevalence in the general population, individuals with…
Illness perception, family resilience, and emotional distress among hospitalized older adults with multimorbidity in Xinjiang, China: a latent profile and mediation analysis
BackgroundOlder adults with multimorbidity frequently encounter significant psychological challenges, with negative illness perception being a prevalent issue. Such perceptions can intensify emotional distress. Family resilience—the ability of a family system to adapt positively to adversity—plays a crucial role in alleviating…
Remimazolam versus propofol on seizure adequacy in electroconvulsive therapy: a retrospective cohort study
ObjectiveElectroconvulsive therapy (ECT) is a core treatment modality for severe mental disorders, and the choice of anesthetic induction agent directly impacts seizure quality and therapeutic outcomes. This study aimed to compare the effects of remimazolam versus propofol on seizure adequacy…
ENVnet provides a global molecular resource of dissolved organic matter
Nature Biotechnology, Published online: 21 July 2026; doi:10.1038/s41587-026-03230-0A resource of dissolved organic matter illuminates carbon and microbial life in Earth’s ecosystems.
A new additive in the opioid supply is causing disastrous complications
Nature Medicine, Published online: 21 July 2026; doi:10.1038/s41591-026-04536-xA new additive in the opioid supply is causing disastrous complications
Genomas Brasil program: building precision public health within Brazil’s Unified Health System
Nature Medicine, Published online: 21 July 2026; doi:10.1038/s41591-026-04523-2Brazil is embedding large-scale genomics into its universal public healthcare system, combining sequencing, infrastructure and clinical implementation at scale. The experience may provide a model for other countries in the global south that…
Individualized antisense oligonucleotides for SCN2A-related developmental epileptic encephalopathy
Nature Medicine, Published online: 21 July 2026; doi:10.1038/s41591-026-04527-yIn two patients with SCN2A epileptic encephalopathy, treatment with personalized allele-selective antisense oligonucleotides led to a decrease in seizure frequency with a positive safety profile.
News Feed
Case Report: Probable paroxysmal sympathetic hyperactivity during vascular and postoperative critical illness with bilateral white matter abnormalities
BackgroundRecognition of paroxysmal sympathetic hyperactivity (PSH) during vascular and postoperative critical illness is complicated by overlapping infection and seizure features.Case presentationA 37-year-old man developed encephalopathy and rigidity after extensive arterial thrombosis, thrombectomy, and suspected…
Single-cell dataset of juvenile mouse neurons from the thalamic reticular nucleus: whole-cell patch-clamp electrophysiology
This dataset provides single-cell whole-cell patch-clamp electrophysiology for 19 interneurons of the thalamic reticular nucleus (TRN) in juvenile mice. The recordings were obtained from male C57Bl/6J mice sampled within the developmental window of postnatal…
A systematic review and meta-analysis of quantitative pain outcomes in degenerative thoracic myelopathy
IntroductionDegenerative thoracic myelopathy (DTM) refers to symptomatic compression of the thoracic spinal cord secondary to degenerative pathology, including thoracic disc herniation (TDH), ossification of the ligamentum flavum (OLF) and ossification of the posterior longitudinal…
News
3067 results
Developing a Text Messaging Intervention to Increase Uptake of the Screening and Treatment for Anxiety and Depression Program Among Community College Students: Formative Study Using a Human-Centered Design Approach
Background: Community college (CC) students face significant mental health concerns but are unlikely to receive treatment. Barriers to mental health service uptake among CC students have been delineated, but few studies have identified strategies to improve uptake. Text messaging has…
Optimizing Treatment Strategies in the Bipolar Disorder Spectrum With Classical AI Approaches: Systematic Review of Performance, Bias, and Clinical Applicability
Background: Bipolar disorder (BD) is a complex and heterogeneous psychiatric condition, characterized by fluctuating clinical courses that affect approximately 1%‐2% of the global population in their lifetime. Despite pharmacological advances, treatment response varies significantly among patients, making the identification of…
Opinion: Pete Hegseth, ‘The Odyssey,’ and the testosterone myth
The poet didn’t say “sing to me, Muse, of a man with optimized endocrine panels," writes urologist Elizabeth Dray.
STAT+: Advocates say federal funding is being cut from groups fighting HIV
The administration is shifting some funding to states, but community groups are set to lose out.
Digital Reassurance Seeking in OCD
– by Jordan Karr, PhD We all need reassurance once in a while. Receiving reassurance from a friend, loved one, or expert can reduce short-term distress, foster a sense of connection,... Read more » The post Digital Reassurance Seeking in OCD…
Is there an exodus underway at Epic?
In this edition of STAT Health Tech: executive departures at Epic Systems, new CEO takes over at Nabla, and more health tech news.
The Download: Chinese AI divides the White House, and a record copyright payout
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. China’s AI models have Trump’s AI world at war with itself Last weekend, several current and…
Curcumin attenuates α-synuclein pathology in Parkinson’s disease model mice through modulation of UBC9-associated SUMOylation signaling
BackgroundPost-translational modifications, particularly SUMOylation, plays a crucial role in α-synuclein (α-syn) aggregation, a key pathological feature of Parkinson’s disease (PD). Curcumin, a natural polyphenol, has shown neuroprotective potential, but its effects on SUMOylation-related signaling in PD remain unclear.ObjectiveThis study aimed…
Targeting mitochondria for the treatment of neurodegenerative diseases
Mitochondria are central regulators of cellular metabolism, redox balance, calcium signaling, and cell survival, making them essential for neuronal function. Because neurons rely heavily on mitochondrial oxidative phosphorylation to meet their high energetic demands, mitochondrial dysfunction has emerged as a…
Venous-significant intracranial hemorrhage in neonatal HIE treated with therapeutic hypothermia: imaging phenotypes, diagnostic pitfalls, and prognostic implications
In the therapeutic hypothermia era, intracranial hemorrhage is increasingly detected in term and near-term neonates with hypoxic–ischemic encephalopathy (HIE), yet its clinical significance remains heterogeneous and is often oversimplified. This review uses a pattern-based approach for venous system–related intracranial hemorrhage…
Subcortical gray matter atrophy and iron deposition in patients with vascular dementia: a multimodal MRI study
PurposeVascular dementia (VAD) is the second most common type of dementia worldwide. Therefore, early detection and diagnosis, along with a clear understanding of its pathogenesis are critical for mitigating disease progression. In the present study, we aimed to elucidate the…
Latest developments in the use of e-cigarettes by people with schizophrenia spectrum disorders who smoke: a scoping review
BackgroundTobacco use is significantly more prevalent among individuals with schizophrenia spectrum disorders (SSD) compared to the general population, contributing to elevated rates of premature mortality from smoking-related diseases. Despite a decline in smoking prevalence in the general population, individuals with…
Illness perception, family resilience, and emotional distress among hospitalized older adults with multimorbidity in Xinjiang, China: a latent profile and mediation analysis
BackgroundOlder adults with multimorbidity frequently encounter significant psychological challenges, with negative illness perception being a prevalent issue. Such perceptions can intensify emotional distress. Family resilience—the ability of a family system to adapt positively to adversity—plays a crucial role in alleviating…
Remimazolam versus propofol on seizure adequacy in electroconvulsive therapy: a retrospective cohort study
ObjectiveElectroconvulsive therapy (ECT) is a core treatment modality for severe mental disorders, and the choice of anesthetic induction agent directly impacts seizure quality and therapeutic outcomes. This study aimed to compare the effects of remimazolam versus propofol on seizure adequacy…
ENVnet provides a global molecular resource of dissolved organic matter
Nature Biotechnology, Published online: 21 July 2026; doi:10.1038/s41587-026-03230-0A resource of dissolved organic matter illuminates carbon and microbial life in Earth’s ecosystems.
A new additive in the opioid supply is causing disastrous complications
Nature Medicine, Published online: 21 July 2026; doi:10.1038/s41591-026-04536-xA new additive in the opioid supply is causing disastrous complications
Genomas Brasil program: building precision public health within Brazil’s Unified Health System
Nature Medicine, Published online: 21 July 2026; doi:10.1038/s41591-026-04523-2Brazil is embedding large-scale genomics into its universal public healthcare system, combining sequencing, infrastructure and clinical implementation at scale. The experience may provide a model for other countries in the global south that…
Individualized antisense oligonucleotides for SCN2A-related developmental epileptic encephalopathy
Nature Medicine, Published online: 21 July 2026; doi:10.1038/s41591-026-04527-yIn two patients with SCN2A epileptic encephalopathy, treatment with personalized allele-selective antisense oligonucleotides led to a decrease in seizure frequency with a positive safety profile.