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3048 results

Source-resolved electroencephalogram microstates reveal opposing prefrontal-posterior dynamics and a candidate temporal-to-precuneus pathway in disorders of consciousness

IntroductionObjective and circuit-level biomarkers of consciousness are urgently needed for disorders of consciousness.MethodsWe recorded high-density electroencephalography from 33 patients with disorders of consciousness (17 vegetative state/unresponsive wakefulness syndrome, 16 minimally conscious state) and 19 healthy controls during rest and auditory…

Tags: Biomarker, Sleep and arousal regulation

Read more

Effects of auditory sensory stimulation on consciousness and physiological parameters among individuals with disorders of consciousness: a systematic review and meta-analysis

ObjectiveTo systematically evaluate the effects of auditory sensory stimulation (SS) on consciousness levels and physiological parameters in patients with disorders of consciousness (DOC). Furthermore, this study aimed to explore intervention characteristics based on the frequency, intensity, time, and type (FITT)…

Tags: Academic research, Medication

Read more

Nogo-related frontal theta-band activity after magnetic seizure therapy in treatment-resistant depression: an exploratory task-based EEG study

IntroductionMagnetic seizure therapy (MST) is an emerging convulsive treatment for treatment-resistant depression (TRD) with efficacy comparable to electroconvulsive therapy and superior cognitive safety. However, its neurophysiological mechanisms—particularly those underlying conflict monitoring and response inhibition—remain unclear. Frontal midline theta-band activity indexes…

Tags: Academic research, Biomarker, Chronic depression, Depression, Mood and emotional regulation

Read more

Impulsivity is the principal correlate of problematic internet use in young adults with attention-deficit/hyperactivity disorder: a cross-sectional clinical study

IntroductionAttention-deficit/hyperactivity disorder (ADHD) and problematic internet use share clinical features such as impulsivity, emotional dysregulation and impaired inhibitory control, but most evidence comes from children, adolescents and non-clinical samples. It remains unclear which dimension carries this association in adults with…

Tags: Academic research, ADHD, Anxiety, Body-focused and impulse habits, Cognitive focus and executive control, Substance abuse, Substance use

Read more

Dance- and movement-based interventions for autism spectrum disorder: a systematic review and exploratory meta-analysis

ObjectivesAutism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by difficulties in social communication, restricted and repetitive behaviors, and impaired adaptive functioning. Although behavioral and developmental interventions remain central to ASD management, the effects of dance- and movement-based interventions…

Tags: Academic research, Autism, Clinical trial, United Kingdom

Read more

Latent profiles of day-7 cognitive performance and associated ecological factors in older adults after elective surgery: an observational study

ObjectiveTo identify latent profiles of postoperative day-7 cognitive performance among older adults after elective surgery and to explore demographic, behavioral, clinical, and social factors associated with profile membership.MethodsThis prospective observational study included 308 consecutively recruited patients aged ≥65 years who…

Tags: Academic research, Sleep and arousal regulation, Substance abuse, Substance use

Read more

Trajectories of perinatal depression, anxiety, perceived stress, sleep quality, and psychological flexibility from pregnancy to six months postpartum and their relationship with the number of abortions and deliveries

BackgroundPerinatal psychological distress is common and longitudinally heterogeneous, yet little is known about how obstetric history shapes symptom trajectories. We identified trajectories of depressive symptoms, perceived stress, sleep quality, psychological flexibility, and anxiety from early pregnancy to 24 weeks postpartum…

Tags: Academic research, Anxiety, Depression, Healthcare provider, Mood and emotional regulation, Sleep and arousal regulation

Read more

Serotonin signaling enhances phagocytosis by brain macrophages through Htr2b and alleviates brain injury after stroke

Nature Neuroscience, Published online: 28 October 2026; doi:10.1038/s41593-026-02482-yThe serotonin receptor Htr2b activation enhances lysosome biogenesis and phagocytic clearance of debris to mitigate neuroinflammation and brain injury after stroke. The study proposes a potential monocyte-derived macrophage-targeted immune therapy to improve neurological…

Tags: Academic research, Medication, Mood and emotional regulation

Read more

Cognitive Neurocomputational Task Reliability and Clinical Applications Consortium: Study 3

Conditions: Schizophrenia / Schizoaffective Disorder; SCHIZOPHRENIA 1 (Disorder); Healthy Adult Interventions: Behavioral: Motion Perception Task; Behavioral: Sine Wave Speech Task; Behavioral: Volatility Task; Behavioral: Choice Probabilistic Reversal Task; Behavioral: Kamin Blocking Task; Behavioral: Minnesota Trust Game; Behavioral: Dynamic Trust Game…

Tags: Academic research, Medication, Mental health, Schizophrenia spectrum, Social and attachment drive, United States

Read more

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Disease
Functional Domain
Type
Source
Reset filters

3048 results

Source-resolved electroencephalogram microstates reveal opposing prefrontal-posterior dynamics and a candidate temporal-to-precuneus pathway in disorders of consciousness

IntroductionObjective and circuit-level biomarkers of consciousness are urgently needed for disorders of consciousness.MethodsWe recorded high-density electroencephalography from 33 patients with disorders of consciousness (17 vegetative state/unresponsive wakefulness syndrome, 16 minimally conscious state) and 19 healthy controls during rest and auditory…

Tags: Biomarker, Sleep and arousal regulation

Read more

Effects of auditory sensory stimulation on consciousness and physiological parameters among individuals with disorders of consciousness: a systematic review and meta-analysis

ObjectiveTo systematically evaluate the effects of auditory sensory stimulation (SS) on consciousness levels and physiological parameters in patients with disorders of consciousness (DOC). Furthermore, this study aimed to explore intervention characteristics based on the frequency, intensity, time, and type (FITT)…

Tags: Academic research, Medication

Read more

Nogo-related frontal theta-band activity after magnetic seizure therapy in treatment-resistant depression: an exploratory task-based EEG study

IntroductionMagnetic seizure therapy (MST) is an emerging convulsive treatment for treatment-resistant depression (TRD) with efficacy comparable to electroconvulsive therapy and superior cognitive safety. However, its neurophysiological mechanisms—particularly those underlying conflict monitoring and response inhibition—remain unclear. Frontal midline theta-band activity indexes…

Tags: Academic research, Biomarker, Chronic depression, Depression, Mood and emotional regulation

Read more

Impulsivity is the principal correlate of problematic internet use in young adults with attention-deficit/hyperactivity disorder: a cross-sectional clinical study

IntroductionAttention-deficit/hyperactivity disorder (ADHD) and problematic internet use share clinical features such as impulsivity, emotional dysregulation and impaired inhibitory control, but most evidence comes from children, adolescents and non-clinical samples. It remains unclear which dimension carries this association in adults with…

Tags: Academic research, ADHD, Anxiety, Body-focused and impulse habits, Cognitive focus and executive control, Substance abuse, Substance use

Read more

Dance- and movement-based interventions for autism spectrum disorder: a systematic review and exploratory meta-analysis

ObjectivesAutism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by difficulties in social communication, restricted and repetitive behaviors, and impaired adaptive functioning. Although behavioral and developmental interventions remain central to ASD management, the effects of dance- and movement-based interventions…

Tags: Academic research, Autism, Clinical trial, United Kingdom

Read more

Latent profiles of day-7 cognitive performance and associated ecological factors in older adults after elective surgery: an observational study

ObjectiveTo identify latent profiles of postoperative day-7 cognitive performance among older adults after elective surgery and to explore demographic, behavioral, clinical, and social factors associated with profile membership.MethodsThis prospective observational study included 308 consecutively recruited patients aged ≥65 years who…

Tags: Academic research, Sleep and arousal regulation, Substance abuse, Substance use

Read more

Trajectories of perinatal depression, anxiety, perceived stress, sleep quality, and psychological flexibility from pregnancy to six months postpartum and their relationship with the number of abortions and deliveries

BackgroundPerinatal psychological distress is common and longitudinally heterogeneous, yet little is known about how obstetric history shapes symptom trajectories. We identified trajectories of depressive symptoms, perceived stress, sleep quality, psychological flexibility, and anxiety from early pregnancy to 24 weeks postpartum…

Tags: Academic research, Anxiety, Depression, Healthcare provider, Mood and emotional regulation, Sleep and arousal regulation

Read more

Serotonin signaling enhances phagocytosis by brain macrophages through Htr2b and alleviates brain injury after stroke

Nature Neuroscience, Published online: 28 October 2026; doi:10.1038/s41593-026-02482-yThe serotonin receptor Htr2b activation enhances lysosome biogenesis and phagocytic clearance of debris to mitigate neuroinflammation and brain injury after stroke. The study proposes a potential monocyte-derived macrophage-targeted immune therapy to improve neurological…

Tags: Academic research, Medication, Mood and emotional regulation

Read more

Cognitive Neurocomputational Task Reliability and Clinical Applications Consortium: Study 3

Conditions: Schizophrenia / Schizoaffective Disorder; SCHIZOPHRENIA 1 (Disorder); Healthy Adult Interventions: Behavioral: Motion Perception Task; Behavioral: Sine Wave Speech Task; Behavioral: Volatility Task; Behavioral: Choice Probabilistic Reversal Task; Behavioral: Kamin Blocking Task; Behavioral: Minnesota Trust Game; Behavioral: Dynamic Trust Game…

Tags: Academic research, Medication, Mental health, Schizophrenia spectrum, Social and attachment drive, United States

Read more