News Feed
Is the oxytocin system a keystone in human wellbeing?
It has also taken over a century for science to fully realize that oxytocin is far more than a “female reproductive hormone.” Both the measurement and interpretation of the biochemical and functional properties of…
Asymmetric encoder-decoder U-net with hybrid attention and residual dilated convolution for brain tumor segmentation
InroductionThe accurate and automatic segmentation of brain tumors from magnetic resonance imaging is regarded as essential for clinical diagnosis and surgical planning. Nevertheless, the concurrent extraction of both local fine details and global contextual…
News
3048 results
A Web-based Intervention Program for Postpartum Depression
Conditions: Postpartum Depression (PPD); Web-based Intervention Interventions: Device: Web-based program for postpartum depression Sponsors: Babes-Bolyai University Recruiting
Symptom severity at first digital self-assessment is not associated with greater subsequent booking of professional care on a Saudi mental health platform: a cohort study of 5,524 users
BackgroundDigital mental health platforms routinely deliver self-administered symptom scales on the assumption that users with more severe symptoms are more likely to enter professional care. That assumption is rarely tested with linked participant-level data, and almost never in the Arabic-speaking…
Effects of different electrical stimulation on depression: a systematic review and network meta-analysis
BackgroundDepression is a prevalent psychiatric disorder characterised by persistent low mood and anhedonia, substantially impairing quality of life. Conventional treatments show variable efficacy and tolerability, with high post-discontinuation relapse rates. Electrical stimulation has emerged as an alternative intervention, but comparative…
Effects of exercise interventions on executive function in adolescents: a systematic review and three-level meta-analysis of randomized controlled trials
ObjectiveTo estimate the effects of exercise interventions lasting at least 4 weeks on overall executive function and its three domains in adolescents, and to explore differences across population subgroups.MethodsNine databases were systematically searched. Individually randomized parallel-group trials of adolescents aged…
Author Correction: Toripalimab or placebo plus chemotherapy as first-line treatment in advanced nasopharyngeal carcinoma: a multicenter randomized phase 3 trial
Nature Medicine, Published online: 27 October 2026; doi:10.1038/s41591-026-04751-6Author Correction: Toripalimab or placebo plus chemotherapy as first-line treatment in advanced nasopharyngeal carcinoma: a multicenter randomized phase 3 trial
Understanding the Different Types of Psychological Evaluations
If your child is struggling with mental health, behavior, or learning challenges, the first step to getting them the support they need is to seek a professional assessment. Whether you’ve been motivated to do so by the child’s teacher, the…
Purrble Use Among LGBTQ+ Young People With Self-Harm Experiences: Findings From a Qualitative Process Evaluation of a Randomized Controlled Trial
Background: Difficulties with emotion regulation (ER) have widely been associated with the development and persistence of poor mental health, such as depression, anxiety, self-harmful thoughts, behaviors, and suicide attempts. Despite the importance of ER as a transdiagnostic risk factor, few…
STAT+: Missouri AG warns Lilly to stop requiring data from hospitals seeking 340B drug discounts
Missouri AG told Lilly to stop forcing hospitals to provide claims data to receive discounted medicines under 340B, a sign more states are pushing back against drugmakers.
STAT+: After two deaths in autoimmune cell therapy trial, Artiva is shutting down
Recent deaths are setbacks in drug companies’ interest in applying cancer therapy strategies to autoimmune diseases.
STAT+: FDA offers new details on quicker approval pathway for personalized gene therapies
Rare disease advocates applauded the FDA's move to speed access to treatments.
Early Research Shows How Postnatal Depression May Affect Offspring
Research suggests that specific microRNAs in breast milk could at least partly explain why many children of women with postnatal depression experience developmental and behavioral problems. The post Early Research Shows How Postnatal Depression May Affect Offspring appeared first on…
Characteristic Facial Expressions During Visual Fixation in Japanese Older Adults With Lower Cognitive Screening Performance: Exploratory Cross-Sectional Study
Background: Early identification of older adults with lower cognitive screening performance may facilitate appropriate clinical evaluation and intervention to delay the progress of cognitive decline and onset of dementia. Because facial information can be acquired noninvasively and unobtrusively during everyday…
STAT+: RFK Jr. goes for broke in Iowa
Kennedy on the campaign trail for MAHA, and new rules loom for U.S. investments in Chinese biotech.
STAT+: Nonprofit resurrects shelved gene therapy after startup shuts down
Last year, U.K. gene therapy startup Bloomsbury Genetic Therapies announced it was shutting down after dosing just one patient. Now, a nonprofit is resurrecting its lead program:
Effects of Telerehabilitation on Quality of Life, Physical Capacity, and Symptom Burden Within the Post–COVID-19 Condition: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Background: Post–COVID-19 condition (PCC) is characterized by persistent symptoms and functional limitations that impair quality of life, and rehabilitation is an important component of its management. Because access to conventional face-to-face rehabilitation may be limited, telerehabilitation has emerged as an…
The Download: Anthropic’s IPO, smarter power grids, and exercise pills
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Will the real Anthropic please stand up? After weeks of frenzied speculation, Anthropic has filed its…
Effects of brain–computer interface output modalities on motor recovery after stroke: a systematic review and network meta-analysis
BackgroundThe relative effects of different brain-computer interface output modalities for post-stroke motor rehabilitation remain unclear.ObjectivesTo synthesize randomized evidence on brain–computer interface-assisted motor rehabilitation after stroke, with emphasis on functional electrical stimulation-triggered and robot-assisted output modalities and the certainty of evidence.MethodsSixteen…
Case Report: Representational geometry of multi-digit coordination in the macaque grasping network for intracortical BCIs
IntroductionIntracortical brain-computer interfaces (BCIs) hold considerable promise for restoring dexterous hand function in individuals with severe paralysis or limb loss. However, reliable control of coordinated multi-digit movements remains challenging because the cortical representation of finger coordination is not fully understood.…
Warfarin anticoagulation control and risks of cerebral small vessel disease and cognitive impairment among elderly patients with ischemic stroke and atrial fibrillation: a retrospective cohort study
ObjectiveThis study applied individual exposure metrics derived from population pharmacokinetic-pharmacodynamic (PopPK/PD) modelling to investigate the associations between warfarin anticoagulation quality, cerebral small vessel disease (CSVD) burden, and cognitive outcomes among older adults with ischemic stroke and non-valvular atrial fibrillation (NVAF).MethodsWe…
News Feed
Is the oxytocin system a keystone in human wellbeing?
It has also taken over a century for science to fully realize that oxytocin is far more than a “female reproductive hormone.” Both the measurement and interpretation of the biochemical and functional properties of…
Asymmetric encoder-decoder U-net with hybrid attention and residual dilated convolution for brain tumor segmentation
InroductionThe accurate and automatic segmentation of brain tumors from magnetic resonance imaging is regarded as essential for clinical diagnosis and surgical planning. Nevertheless, the concurrent extraction of both local fine details and global contextual…
News
3048 results
A Web-based Intervention Program for Postpartum Depression
Conditions: Postpartum Depression (PPD); Web-based Intervention Interventions: Device: Web-based program for postpartum depression Sponsors: Babes-Bolyai University Recruiting
Symptom severity at first digital self-assessment is not associated with greater subsequent booking of professional care on a Saudi mental health platform: a cohort study of 5,524 users
BackgroundDigital mental health platforms routinely deliver self-administered symptom scales on the assumption that users with more severe symptoms are more likely to enter professional care. That assumption is rarely tested with linked participant-level data, and almost never in the Arabic-speaking…
Effects of different electrical stimulation on depression: a systematic review and network meta-analysis
BackgroundDepression is a prevalent psychiatric disorder characterised by persistent low mood and anhedonia, substantially impairing quality of life. Conventional treatments show variable efficacy and tolerability, with high post-discontinuation relapse rates. Electrical stimulation has emerged as an alternative intervention, but comparative…
Effects of exercise interventions on executive function in adolescents: a systematic review and three-level meta-analysis of randomized controlled trials
ObjectiveTo estimate the effects of exercise interventions lasting at least 4 weeks on overall executive function and its three domains in adolescents, and to explore differences across population subgroups.MethodsNine databases were systematically searched. Individually randomized parallel-group trials of adolescents aged…
Author Correction: Toripalimab or placebo plus chemotherapy as first-line treatment in advanced nasopharyngeal carcinoma: a multicenter randomized phase 3 trial
Nature Medicine, Published online: 27 October 2026; doi:10.1038/s41591-026-04751-6Author Correction: Toripalimab or placebo plus chemotherapy as first-line treatment in advanced nasopharyngeal carcinoma: a multicenter randomized phase 3 trial
Understanding the Different Types of Psychological Evaluations
If your child is struggling with mental health, behavior, or learning challenges, the first step to getting them the support they need is to seek a professional assessment. Whether you’ve been motivated to do so by the child’s teacher, the…
Purrble Use Among LGBTQ+ Young People With Self-Harm Experiences: Findings From a Qualitative Process Evaluation of a Randomized Controlled Trial
Background: Difficulties with emotion regulation (ER) have widely been associated with the development and persistence of poor mental health, such as depression, anxiety, self-harmful thoughts, behaviors, and suicide attempts. Despite the importance of ER as a transdiagnostic risk factor, few…
STAT+: Missouri AG warns Lilly to stop requiring data from hospitals seeking 340B drug discounts
Missouri AG told Lilly to stop forcing hospitals to provide claims data to receive discounted medicines under 340B, a sign more states are pushing back against drugmakers.
STAT+: After two deaths in autoimmune cell therapy trial, Artiva is shutting down
Recent deaths are setbacks in drug companies’ interest in applying cancer therapy strategies to autoimmune diseases.
STAT+: FDA offers new details on quicker approval pathway for personalized gene therapies
Rare disease advocates applauded the FDA's move to speed access to treatments.
Early Research Shows How Postnatal Depression May Affect Offspring
Research suggests that specific microRNAs in breast milk could at least partly explain why many children of women with postnatal depression experience developmental and behavioral problems. The post Early Research Shows How Postnatal Depression May Affect Offspring appeared first on…
Characteristic Facial Expressions During Visual Fixation in Japanese Older Adults With Lower Cognitive Screening Performance: Exploratory Cross-Sectional Study
Background: Early identification of older adults with lower cognitive screening performance may facilitate appropriate clinical evaluation and intervention to delay the progress of cognitive decline and onset of dementia. Because facial information can be acquired noninvasively and unobtrusively during everyday…
STAT+: RFK Jr. goes for broke in Iowa
Kennedy on the campaign trail for MAHA, and new rules loom for U.S. investments in Chinese biotech.
STAT+: Nonprofit resurrects shelved gene therapy after startup shuts down
Last year, U.K. gene therapy startup Bloomsbury Genetic Therapies announced it was shutting down after dosing just one patient. Now, a nonprofit is resurrecting its lead program:
Effects of Telerehabilitation on Quality of Life, Physical Capacity, and Symptom Burden Within the Post–COVID-19 Condition: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Background: Post–COVID-19 condition (PCC) is characterized by persistent symptoms and functional limitations that impair quality of life, and rehabilitation is an important component of its management. Because access to conventional face-to-face rehabilitation may be limited, telerehabilitation has emerged as an…
The Download: Anthropic’s IPO, smarter power grids, and exercise pills
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Will the real Anthropic please stand up? After weeks of frenzied speculation, Anthropic has filed its…
Effects of brain–computer interface output modalities on motor recovery after stroke: a systematic review and network meta-analysis
BackgroundThe relative effects of different brain-computer interface output modalities for post-stroke motor rehabilitation remain unclear.ObjectivesTo synthesize randomized evidence on brain–computer interface-assisted motor rehabilitation after stroke, with emphasis on functional electrical stimulation-triggered and robot-assisted output modalities and the certainty of evidence.MethodsSixteen…
Case Report: Representational geometry of multi-digit coordination in the macaque grasping network for intracortical BCIs
IntroductionIntracortical brain-computer interfaces (BCIs) hold considerable promise for restoring dexterous hand function in individuals with severe paralysis or limb loss. However, reliable control of coordinated multi-digit movements remains challenging because the cortical representation of finger coordination is not fully understood.…
Warfarin anticoagulation control and risks of cerebral small vessel disease and cognitive impairment among elderly patients with ischemic stroke and atrial fibrillation: a retrospective cohort study
ObjectiveThis study applied individual exposure metrics derived from population pharmacokinetic-pharmacodynamic (PopPK/PD) modelling to investigate the associations between warfarin anticoagulation quality, cerebral small vessel disease (CSVD) burden, and cognitive outcomes among older adults with ischemic stroke and non-valvular atrial fibrillation (NVAF).MethodsWe…