News Feed
Implementation Strategies for a Technology-Based Bullying Bystander Intervention (STAC-T): Mixed Methods Study
Background: Nearly 1 in 5 students aged 12-18 years report being bullied in the United States. Both targets and students who witness bullying experience negative mental health outcomes. School-based programs are effective in decreasing…
Building the Future of AAV Gene Therapy
This eBook brings together perspectives from across the AAV development and manufacturing continuum. It explores how early commercial planning can help avoid costly delays, how standardized platform approaches and off-the-shelf plasmids can streamline development,…
Hamburg Hosts 2026 European Gene Therapy Conference
GEN's Kevin Davies, PhD, reports from ESGCT where patient safety, expanding access to gene therapy, and progress towards an HIV vaccine were prominent themes among the early talks at ESGCT 2026. The post Hamburg…
News
3068 results
A Self-Guided Mobile Mindfulness Intervention Embedded in Daily Routines for Adults With Mild to Moderate Psychological Distress: Randomized Controlled Trial
Background: Mobile mindfulness interventions have shown promise for reducing anxiety and depressive symptoms, but sustaining engagement remains a persistent challenge. Many digital programs still rely on formal practice that requires dedicated time, which may be difficult to integrate into daily…
enDigital Postpartum Support for Early Risk Identification Among Postpartum Women: Formative Randomized Evaluation and Exploratory Predictive Modeling Study
Background: The postpartum period represents a critical window for maternal health, yet many individuals lack sustained support and timely identification of physical and mental health risks. Digital health interventions offer a scalable approach to extend care beyond clinical settings. Yet,…
STAT+: At key hearing, Kennedy’s ouster of former CDC director looms over nominee to replace her
Erica Schwartz and Sean Kaufman navigated tough questions about vaccines, political independence, and pushing back on RFK Jr.
STAT+: New study untangles how Epstein-Barr viral infection triggers immune response in multiple sclerosis
A new study claims to have uncovered how Epstein-Barr virus launches immune responses seen in people with multiple sclerosis.
STAT+: Improvements in Alzheimer’s testing could make diagnostics more accessible, informative
Alzheimer's research is moving in new directions, finding ways to make testing much more accessible, and offering more nuanced results.
Cassidy grills Trump nominee on past vaccine comments in heated exchange
Sean Kaufman, Trump's pick for a key pandemic preparedness role, has questioned vaccines and criticized the CDC.
Meet GPT-Red: an LLM super-hacker OpenAI built to make its models safer
OpenAI has built an LLM super-hacker called GPT-Red that it uses as a sparring partner to help its other models boost their defenses against cyberattacks. Last week the company released the latest version of its flagship LLM, GPT-5.6. OpenAI says…
Blood Test Foresees Decline into Alzheimer’s Disease
Elevated levels of the blood-based biomarker phosphorylated tau 217 were associated with future cognitive decline in people who were previously unaffected by this, singling out those who might benefit most from disease-modifying treatments. The post Blood Test Foresees Decline into…
BFRBs vs. OCD: Similarities and Differences
This blog was originally posted by the TLC Foundation for BFRBs Body-focused repetitive behaviors (BFRBs) and obsessive-compulsive disorder (OCD) are two distinct mental health conditions that share some similarities but... Read more » The post BFRBs vs. OCD: Similarities and…
Neurophysiological basis for visual distortions in amblyopia
Despite decades of research, the neural basis of visual distortions in amblyopia remains poorly understood. While numerous studies have reported abnormalities in both early visual cortex and extrastriate areas, these findings have rarely been integrated into a unified mechanistic framework.…
Mouse model of Angelman syndrome exhibits reduced retinal activity during development
Angelman Syndrome (AS) is a neurodevelopmental disorder characterized by intellectual disability, seizures, and motor dysfunction caused by loss of function of the maternal UBE3A allele. A large proportion of patients exhibit visual impairments, but the underlying circuit-level mechanisms are not…
Biomarker value of plasma endothelial microvesicle-derived circRNA 0006222 in vascular ageing and carotid atherosclerosis
BackgroundEndothelial microvesicles (EMVs) carrying circular RNAs (circRNAs) have emerged as promising novel biomarkers of ageing-associated disorders. This study investigated the potential of plasma EMVs-circ_0006222 as vascular ageing (VA) and carotid atherosclerosis (CAS) biomarkers.MethodsA circRNA microarray was applied to screen for…
Verbal fluency after cochlear implantation: a longitudinal comparison with untreated hearing loss in the ELSA cohort
IntroductionHearing loss is associated with accelerated cognitive decline, and auditory rehabilitation via cochlear implantation (CI) may mitigate this trajectory. In the past, the impact of cochlear implantation on different cognitive subdomains has been described. However, verbal fluency (VF), which requires…
Traumatic brain injury and neurological stealth syndromes
IntroductionA traumatic brain injury (TBI) of mild or more severe degree affects approximately ½ of the global population at some stage of their life. Mild TBI occurs in 70–90%, with 30 and 50% having symptoms persisting for more than 6 months.…
Gone fishin’… for distinct patterns of belief-updating in late-life worry and rumination
IntroductionWorry and rumination are two common forms of repetitive negative thinking encountered as core symptoms of anxiety and depression. They are difficult to treat and increase the risk of relapse for remitted depressive and anxiety disorders, especially in late-life. We…
From promise to practice: artificial intelligence in mental health care in the MENA region
Mental health disorders represent a growing burden across the Middle East and North Africa (MENA) region, where depression and anxiety are highly prevalent amid conflict, displacement, and socioeconomic strain, affecting up to 40 percent of adults, yet treatment gaps remain…
High perceived energy: exploring distinct patterns of energetic and cognitive functioning in older adults
BackgroundA hyperthymic temperament and high perceived energy are often framed as positive dispositional traits, particularly in later life. Indeed, these characteristics are generally associated with a greater tendency to preserve autonomy and with more favorable outcomes in terms of health,…
Beyond Theory of Mind: mentalization as a relational and developmental framework for autism
Autistic individuals and those around them often navigate social and emotional situations in which behaviors, intentions, and affects are difficult to interpret. Supporting mentalizing processes within child–caregiver interactions may help address these challenges; however, a broader conceptual shift is needed,…
Construction and validation of multiple machine learning models for influencing factors of postpartum post-traumatic stress disorder in primiparas
ObjectiveTo analyze the multidimensional factors associated with postpartum post-traumatic stress disorder (PP-PTSD) in primiparas based on the Integrated Framework for Population Health Risk Management (IFPHRM), multiple machine learning-based predictive models were constructed and externally validated to identify high-risk individuals and…
Multiscale in vivo imaging of tumor evolution using a germline conditional triple-reporter mouse
Nature Biotechnology, Published online: 15 July 2026; doi:10.1038/s41587-026-03184-3Tumors are imaged across scales—from cells to whole body—with a triple-reporter mouse.
News Feed
Implementation Strategies for a Technology-Based Bullying Bystander Intervention (STAC-T): Mixed Methods Study
Background: Nearly 1 in 5 students aged 12-18 years report being bullied in the United States. Both targets and students who witness bullying experience negative mental health outcomes. School-based programs are effective in decreasing…
Building the Future of AAV Gene Therapy
This eBook brings together perspectives from across the AAV development and manufacturing continuum. It explores how early commercial planning can help avoid costly delays, how standardized platform approaches and off-the-shelf plasmids can streamline development,…
Hamburg Hosts 2026 European Gene Therapy Conference
GEN's Kevin Davies, PhD, reports from ESGCT where patient safety, expanding access to gene therapy, and progress towards an HIV vaccine were prominent themes among the early talks at ESGCT 2026. The post Hamburg…
News
3068 results
A Self-Guided Mobile Mindfulness Intervention Embedded in Daily Routines for Adults With Mild to Moderate Psychological Distress: Randomized Controlled Trial
Background: Mobile mindfulness interventions have shown promise for reducing anxiety and depressive symptoms, but sustaining engagement remains a persistent challenge. Many digital programs still rely on formal practice that requires dedicated time, which may be difficult to integrate into daily…
enDigital Postpartum Support for Early Risk Identification Among Postpartum Women: Formative Randomized Evaluation and Exploratory Predictive Modeling Study
Background: The postpartum period represents a critical window for maternal health, yet many individuals lack sustained support and timely identification of physical and mental health risks. Digital health interventions offer a scalable approach to extend care beyond clinical settings. Yet,…
STAT+: At key hearing, Kennedy’s ouster of former CDC director looms over nominee to replace her
Erica Schwartz and Sean Kaufman navigated tough questions about vaccines, political independence, and pushing back on RFK Jr.
STAT+: New study untangles how Epstein-Barr viral infection triggers immune response in multiple sclerosis
A new study claims to have uncovered how Epstein-Barr virus launches immune responses seen in people with multiple sclerosis.
STAT+: Improvements in Alzheimer’s testing could make diagnostics more accessible, informative
Alzheimer's research is moving in new directions, finding ways to make testing much more accessible, and offering more nuanced results.
Cassidy grills Trump nominee on past vaccine comments in heated exchange
Sean Kaufman, Trump's pick for a key pandemic preparedness role, has questioned vaccines and criticized the CDC.
Meet GPT-Red: an LLM super-hacker OpenAI built to make its models safer
OpenAI has built an LLM super-hacker called GPT-Red that it uses as a sparring partner to help its other models boost their defenses against cyberattacks. Last week the company released the latest version of its flagship LLM, GPT-5.6. OpenAI says…
Blood Test Foresees Decline into Alzheimer’s Disease
Elevated levels of the blood-based biomarker phosphorylated tau 217 were associated with future cognitive decline in people who were previously unaffected by this, singling out those who might benefit most from disease-modifying treatments. The post Blood Test Foresees Decline into…
BFRBs vs. OCD: Similarities and Differences
This blog was originally posted by the TLC Foundation for BFRBs Body-focused repetitive behaviors (BFRBs) and obsessive-compulsive disorder (OCD) are two distinct mental health conditions that share some similarities but... Read more » The post BFRBs vs. OCD: Similarities and…
Neurophysiological basis for visual distortions in amblyopia
Despite decades of research, the neural basis of visual distortions in amblyopia remains poorly understood. While numerous studies have reported abnormalities in both early visual cortex and extrastriate areas, these findings have rarely been integrated into a unified mechanistic framework.…
Mouse model of Angelman syndrome exhibits reduced retinal activity during development
Angelman Syndrome (AS) is a neurodevelopmental disorder characterized by intellectual disability, seizures, and motor dysfunction caused by loss of function of the maternal UBE3A allele. A large proportion of patients exhibit visual impairments, but the underlying circuit-level mechanisms are not…
Biomarker value of plasma endothelial microvesicle-derived circRNA 0006222 in vascular ageing and carotid atherosclerosis
BackgroundEndothelial microvesicles (EMVs) carrying circular RNAs (circRNAs) have emerged as promising novel biomarkers of ageing-associated disorders. This study investigated the potential of plasma EMVs-circ_0006222 as vascular ageing (VA) and carotid atherosclerosis (CAS) biomarkers.MethodsA circRNA microarray was applied to screen for…
Verbal fluency after cochlear implantation: a longitudinal comparison with untreated hearing loss in the ELSA cohort
IntroductionHearing loss is associated with accelerated cognitive decline, and auditory rehabilitation via cochlear implantation (CI) may mitigate this trajectory. In the past, the impact of cochlear implantation on different cognitive subdomains has been described. However, verbal fluency (VF), which requires…
Traumatic brain injury and neurological stealth syndromes
IntroductionA traumatic brain injury (TBI) of mild or more severe degree affects approximately ½ of the global population at some stage of their life. Mild TBI occurs in 70–90%, with 30 and 50% having symptoms persisting for more than 6 months.…
Gone fishin’… for distinct patterns of belief-updating in late-life worry and rumination
IntroductionWorry and rumination are two common forms of repetitive negative thinking encountered as core symptoms of anxiety and depression. They are difficult to treat and increase the risk of relapse for remitted depressive and anxiety disorders, especially in late-life. We…
From promise to practice: artificial intelligence in mental health care in the MENA region
Mental health disorders represent a growing burden across the Middle East and North Africa (MENA) region, where depression and anxiety are highly prevalent amid conflict, displacement, and socioeconomic strain, affecting up to 40 percent of adults, yet treatment gaps remain…
High perceived energy: exploring distinct patterns of energetic and cognitive functioning in older adults
BackgroundA hyperthymic temperament and high perceived energy are often framed as positive dispositional traits, particularly in later life. Indeed, these characteristics are generally associated with a greater tendency to preserve autonomy and with more favorable outcomes in terms of health,…
Beyond Theory of Mind: mentalization as a relational and developmental framework for autism
Autistic individuals and those around them often navigate social and emotional situations in which behaviors, intentions, and affects are difficult to interpret. Supporting mentalizing processes within child–caregiver interactions may help address these challenges; however, a broader conceptual shift is needed,…
Construction and validation of multiple machine learning models for influencing factors of postpartum post-traumatic stress disorder in primiparas
ObjectiveTo analyze the multidimensional factors associated with postpartum post-traumatic stress disorder (PP-PTSD) in primiparas based on the Integrated Framework for Population Health Risk Management (IFPHRM), multiple machine learning-based predictive models were constructed and externally validated to identify high-risk individuals and…
Multiscale in vivo imaging of tumor evolution using a germline conditional triple-reporter mouse
Nature Biotechnology, Published online: 15 July 2026; doi:10.1038/s41587-026-03184-3Tumors are imaged across scales—from cells to whole body—with a triple-reporter mouse.