News Feed
Saliva-Based Proteomics Reveals Immune Changes Linked to Oral Cancer Progression
A new single-cell proteomics approach has revealed distinct immune-cell protein signatures associated with oral cancer progression and lymph node involvement. The findings could pave the way for noninvasive saliva tests to help assess disease…
Digitally Assisted Training System for Home-Based Scoliosis Therapy: Proof-of-Concept and Technical Verification Study
Background: Schroth therapy is one of the conservative methods used to treat scoliosis. It includes not only therapeutic exercises in physiotherapy facilities but also concepts for independent training at home. Consistent and correct performance…
Cocreating a Climate and Health Dashboard With Multisector Stakeholders: Qualitative Pilot Study
Background: Climate-related disasters increasingly affect community health, health care access, and disaster preparedness, particularly in disaster-prone Gulf Coast communities. Although climate dashboards have expanded access to environmental data, many function primarily as static repositories…
News
3068 results
Modeling Short-Term Symptom Changes and Behavioral Subtypes of Depression and Anxiety in the General Population: Observational Study Using Smartphone Data
Background: Smartphone-based digital phenotyping has emerged as a promising approach for monitoring mental health using passive behavioral data. Prior studies have linked smartphone-derived features to depression and anxiety severity; however, knowledge regarding whether short-term changes in symptoms can be captured…
Active Ingredients in Digital Cognitive Interventions: Integrating Dismantling Designs With Mechanistic Neuroscience
Digital cognitive interventions (DCIs) have emerged as scalable approaches for treating cognitive dysfunction across psychiatric, neurological, and aging populations. Despite growing evidence of efficacy, little is known about which intervention components drive therapeutic effects or through which neurocognitive mechanisms they…
STAT+: FTC settles lawsuit with CVS Caremark over charges it manipulated insulin prices, impeded access
The FTC settled a lawsuit against CVS Caremark over allegations that the company artificially inflated the price of insulin and impeded access to the diabetes treatment.
STAT+: Sales from controversial U.S. drug discount program rose to $100 billion last year
Prescription drugs purchased under a controversial government discount program amounted to $100 billion in 2025, a 22.8% increase from the previous year.
As cyclospora illnesses surge to a record, Michigan officials eye lettuce as a possible cause
Infections from the diarrhea-causing parasite cyclospora are surging, and officials say early information points to lettuce or salad greens as a possible culprit.
STAT+: Top Democrats question RFK Jr.’s health care advisory panel
Democratic senators question presence of Trump donors, Tony Robbins on health care advisory panel.
STAT+: Hospital chain HCA warns of lower profits as more patients go uninsured
It's an early indicator of the fallout from the end of extra ACA subsidies.
Humanized APOE mouse brain volume increases over age irrespective of sex and APOE genotype: implications for translational validity to the human
BackgroundHumanized APOE mouse models are widely used to study late-onset Alzheimer’s disease (LOAD) risk, yet it remains unclear whether they reproduce the macrostructural brain changes observed in human aging and disease.MethodsWe performed ex vivo magnetic resonance imaging to quantify total…
Selective reduction of the light peak-to-dark trough ratio in reticular macular disease: an electrooculography study
PurposeTo compare electrooculogram (EOG) parameters between eyes with reticular macular disease (RMD) and eyes with early-to-intermediate age-related macular degeneration (AMD) without reticular pseudodrusen (RPD), and to assess whether RMD is associated with generalized RPE–photoreceptor complex dysfunction.MethodsIn this observational cross-sectional study,…
Modelling learning dynamics in autism therapy through explainable multimodal representation learning
BackgroundAutism Spectrum Disorder (ASD) presents with complex, temporally evolving motor and social behaviours that are difficult to quantify in ecologically valid clinical contexts. While recent computational methods offer diagnostic insights, many depend on fully supervised learning, high-resolution video, or artificial…
Circadian–immune crosstalk in insomnia disorder: mechanisms and therapeutic implications
Insomnia disorder (ID) is a common sleep–wake disorder characterized by persistent difficulty initiating or maintaining sleep, early-morning awakening, or non-restorative sleep, accompanied by daytime functional impairment. ID has traditionally been explained by the hyperarousal model, which emphasizes cognitive, emotional, cortical,…
A hybrid implementation-effectiveness study of a school-based intervention for promoting health and well-being in low-resource settings: the ISOBAR study protocol
IntroductionSchool-based interventions can improve adolescent health outcomes and tackle the growing burden of non-communicable diseases (NCDs) in low-and-middle-income countries (LMICs). Results to date are variable, partly due to lack of cultural adaptation of Westernised models and limited focus on implementation…
Perception and willingness toward second-generation long-acting antipsychotics among patients with schizophrenia: a cross-sectional survey in Fujian, China
ObjectiveTo assess perceptions and willingness toward second-generation antipsychotic long-acting injectables (SGA-LAIs) among patients with schizophrenia, to identify the influencing factors, and to provide evidence for optimizing clinical implementation strategies.MethodsA cross-sectional survey was conducted in which patients with schizophrenia who attended…
Probing the linguistic cerebellum: a qualitative review of the effects of cerebellar neurostimulation on language processing
The cerebellum has historically been underrepresented in language research. However, converging evidence from lesion and neuroimaging studies supports its crucial involvement in phonological and semantic aspects of language processing, highlighting the relevance of cerebro-cerebellar circuits in language-related functions. Likewise, cerebellar…
Occupational burnout and risk of suicidality in healthcare professionals: a PRISMA-guided systematic review
BackgroundBurnout, an occupational phenomenon resulting from chronic workplace stress that has not been successfully managed, is increasingly recognized as a critical threat to the mental health of healthcare professionals. Prolonged exposure to work-related stressors may increase the risk of suicidality,…
Coping styles and mental health outcomes in partners who have experienced a perinatal loss: a longitudinal study
Perinatal loss is common, but little is known about its impact on partners during the grieving process. This study examined psychological outcomes and coping strategies among recently bereaved partners (≤6 months post-loss; N = 73) at baseline (T1) and six-month follow-up (T2)…
Oxytocin promotes socially triggered cataplexy
Nature Neuroscience, Published online: 14 July 2026; doi:10.1038/s41593-026-02352-7In people with narcolepsy, cataplexy is often triggered by strong emotions in social situations. Mahoney et al. show that such cataplexy is mediated by oxytocin-responsive neurons in the amygdala that target brainstem regions…
A framework for comparative analysis of human and mouse cortical neuron dendrites in corresponding brain regions
Nature Neuroscience, Published online: 14 July 2026; doi:10.1038/s41593-026-02376-zThis study establishes a region-matched framework for comparing single-neuron dendritic morphology in human and mouse cortex, revealing more compact local dendrites and stronger lobe-level morphological specialization in humans.
The Download: Claude’s inner workings, and the future of world models
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. What Anthropic’s latest AI discovery does—and doesn’t—show —James O’Donnell When Anthropic announced last week that it…
News Feed
Saliva-Based Proteomics Reveals Immune Changes Linked to Oral Cancer Progression
A new single-cell proteomics approach has revealed distinct immune-cell protein signatures associated with oral cancer progression and lymph node involvement. The findings could pave the way for noninvasive saliva tests to help assess disease…
Digitally Assisted Training System for Home-Based Scoliosis Therapy: Proof-of-Concept and Technical Verification Study
Background: Schroth therapy is one of the conservative methods used to treat scoliosis. It includes not only therapeutic exercises in physiotherapy facilities but also concepts for independent training at home. Consistent and correct performance…
Cocreating a Climate and Health Dashboard With Multisector Stakeholders: Qualitative Pilot Study
Background: Climate-related disasters increasingly affect community health, health care access, and disaster preparedness, particularly in disaster-prone Gulf Coast communities. Although climate dashboards have expanded access to environmental data, many function primarily as static repositories…
News
3068 results
Modeling Short-Term Symptom Changes and Behavioral Subtypes of Depression and Anxiety in the General Population: Observational Study Using Smartphone Data
Background: Smartphone-based digital phenotyping has emerged as a promising approach for monitoring mental health using passive behavioral data. Prior studies have linked smartphone-derived features to depression and anxiety severity; however, knowledge regarding whether short-term changes in symptoms can be captured…
Active Ingredients in Digital Cognitive Interventions: Integrating Dismantling Designs With Mechanistic Neuroscience
Digital cognitive interventions (DCIs) have emerged as scalable approaches for treating cognitive dysfunction across psychiatric, neurological, and aging populations. Despite growing evidence of efficacy, little is known about which intervention components drive therapeutic effects or through which neurocognitive mechanisms they…
STAT+: FTC settles lawsuit with CVS Caremark over charges it manipulated insulin prices, impeded access
The FTC settled a lawsuit against CVS Caremark over allegations that the company artificially inflated the price of insulin and impeded access to the diabetes treatment.
STAT+: Sales from controversial U.S. drug discount program rose to $100 billion last year
Prescription drugs purchased under a controversial government discount program amounted to $100 billion in 2025, a 22.8% increase from the previous year.
As cyclospora illnesses surge to a record, Michigan officials eye lettuce as a possible cause
Infections from the diarrhea-causing parasite cyclospora are surging, and officials say early information points to lettuce or salad greens as a possible culprit.
STAT+: Top Democrats question RFK Jr.’s health care advisory panel
Democratic senators question presence of Trump donors, Tony Robbins on health care advisory panel.
STAT+: Hospital chain HCA warns of lower profits as more patients go uninsured
It's an early indicator of the fallout from the end of extra ACA subsidies.
Humanized APOE mouse brain volume increases over age irrespective of sex and APOE genotype: implications for translational validity to the human
BackgroundHumanized APOE mouse models are widely used to study late-onset Alzheimer’s disease (LOAD) risk, yet it remains unclear whether they reproduce the macrostructural brain changes observed in human aging and disease.MethodsWe performed ex vivo magnetic resonance imaging to quantify total…
Selective reduction of the light peak-to-dark trough ratio in reticular macular disease: an electrooculography study
PurposeTo compare electrooculogram (EOG) parameters between eyes with reticular macular disease (RMD) and eyes with early-to-intermediate age-related macular degeneration (AMD) without reticular pseudodrusen (RPD), and to assess whether RMD is associated with generalized RPE–photoreceptor complex dysfunction.MethodsIn this observational cross-sectional study,…
Modelling learning dynamics in autism therapy through explainable multimodal representation learning
BackgroundAutism Spectrum Disorder (ASD) presents with complex, temporally evolving motor and social behaviours that are difficult to quantify in ecologically valid clinical contexts. While recent computational methods offer diagnostic insights, many depend on fully supervised learning, high-resolution video, or artificial…
Circadian–immune crosstalk in insomnia disorder: mechanisms and therapeutic implications
Insomnia disorder (ID) is a common sleep–wake disorder characterized by persistent difficulty initiating or maintaining sleep, early-morning awakening, or non-restorative sleep, accompanied by daytime functional impairment. ID has traditionally been explained by the hyperarousal model, which emphasizes cognitive, emotional, cortical,…
A hybrid implementation-effectiveness study of a school-based intervention for promoting health and well-being in low-resource settings: the ISOBAR study protocol
IntroductionSchool-based interventions can improve adolescent health outcomes and tackle the growing burden of non-communicable diseases (NCDs) in low-and-middle-income countries (LMICs). Results to date are variable, partly due to lack of cultural adaptation of Westernised models and limited focus on implementation…
Perception and willingness toward second-generation long-acting antipsychotics among patients with schizophrenia: a cross-sectional survey in Fujian, China
ObjectiveTo assess perceptions and willingness toward second-generation antipsychotic long-acting injectables (SGA-LAIs) among patients with schizophrenia, to identify the influencing factors, and to provide evidence for optimizing clinical implementation strategies.MethodsA cross-sectional survey was conducted in which patients with schizophrenia who attended…
Probing the linguistic cerebellum: a qualitative review of the effects of cerebellar neurostimulation on language processing
The cerebellum has historically been underrepresented in language research. However, converging evidence from lesion and neuroimaging studies supports its crucial involvement in phonological and semantic aspects of language processing, highlighting the relevance of cerebro-cerebellar circuits in language-related functions. Likewise, cerebellar…
Occupational burnout and risk of suicidality in healthcare professionals: a PRISMA-guided systematic review
BackgroundBurnout, an occupational phenomenon resulting from chronic workplace stress that has not been successfully managed, is increasingly recognized as a critical threat to the mental health of healthcare professionals. Prolonged exposure to work-related stressors may increase the risk of suicidality,…
Coping styles and mental health outcomes in partners who have experienced a perinatal loss: a longitudinal study
Perinatal loss is common, but little is known about its impact on partners during the grieving process. This study examined psychological outcomes and coping strategies among recently bereaved partners (≤6 months post-loss; N = 73) at baseline (T1) and six-month follow-up (T2)…
Oxytocin promotes socially triggered cataplexy
Nature Neuroscience, Published online: 14 July 2026; doi:10.1038/s41593-026-02352-7In people with narcolepsy, cataplexy is often triggered by strong emotions in social situations. Mahoney et al. show that such cataplexy is mediated by oxytocin-responsive neurons in the amygdala that target brainstem regions…
A framework for comparative analysis of human and mouse cortical neuron dendrites in corresponding brain regions
Nature Neuroscience, Published online: 14 July 2026; doi:10.1038/s41593-026-02376-zThis study establishes a region-matched framework for comparing single-neuron dendritic morphology in human and mouse cortex, revealing more compact local dendrites and stronger lobe-level morphological specialization in humans.
The Download: Claude’s inner workings, and the future of world models
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. What Anthropic’s latest AI discovery does—and doesn’t—show —James O’Donnell When Anthropic announced last week that it…