News Feed
Saliva-Based Proteomics Reveals Immune Changes Linked to Oral Cancer Progression
A new single-cell proteomics approach has revealed distinct immune-cell protein signatures associated with oral cancer progression and lymph node involvement. The findings could pave the way for noninvasive saliva tests to help assess disease…
Digitally Assisted Training System for Home-Based Scoliosis Therapy: Proof-of-Concept and Technical Verification Study
Background: Schroth therapy is one of the conservative methods used to treat scoliosis. It includes not only therapeutic exercises in physiotherapy facilities but also concepts for independent training at home. Consistent and correct performance…
Cocreating a Climate and Health Dashboard With Multisector Stakeholders: Qualitative Pilot Study
Background: Climate-related disasters increasingly affect community health, health care access, and disaster preparedness, particularly in disaster-prone Gulf Coast communities. Although climate dashboards have expanded access to environmental data, many function primarily as static repositories…
News
3068 results
ADAR-based DNA adenine base editing with single-nucleotide precision
Nature Biotechnology, Published online: 15 July 2026; doi:10.1038/s41587-026-03228-8Adenosine deaminases acting on RNA (ADARs) have not been previously exploited for DNA adenine base editing in mammals. We developed a single-nucleotide-resolution adenine base editor (snuABE) that uses ADAR and customized guide RNAs…
High numerical aperture confocal volumetric mesoscope reveals mesoscale subcellular dynamics in vivo
Nature Biotechnology, Published online: 15 July 2026; doi:10.1038/s41587-026-03231-zVolumetric mesoscale imaging reveals subcellular immune dynamics in different mammalian organs.
High-fidelity fast fluorescence lifetime imaging by event-based denoising
Nature Biotechnology, Published online: 15 July 2026; doi:10.1038/s41587-026-03222-0Event-based first-photon fluorescence lifetime imaging enables fluorescence lifetime imaging below one photon per pixel.
When caution becomes harm
Nature Medicine, Published online: 15 July 2026; doi:10.1038/s41591-026-04526-zOur pregnant patients deserve accurate conversations about risk.
Multi-omics maps human–pig interactions in extracorporeal liver cross-circulation
Nature Medicine, Published online: 15 July 2026; doi:10.1038/s41591-026-04515-2Spatial and circulating multi-omics of pig-to-human extracorporeal liver cross-circulation reveals an early innate immune response, species-specific complement dynamics and xenograft–platelet interactions, while showing preserved metabolic support even after removal of the native liver.…
Fertilizer scarcity as a failure of global health governance
Nature Medicine, Published online: 15 July 2026; doi:10.1038/s41591-026-04507-2Fertilizer scarcity as a failure of global health governance
Studying vanishing dietary diversity before it is lost: the World Diet Initiative
Nature Medicine, Published online: 15 July 2026; doi:10.1038/s41591-026-04520-5Heritage diets are disappearing as food systems homogenize; their effects on immunity, metabolism and host–microbiome biology remain poorly understood. The World Diet Initiative offers a framework to document heritage diets and investigate their…
Oligonucleotide–siRNA conjugate for SOD1 amyotrophic lateral sclerosis: a phase 1 trial
Nature Medicine, Published online: 15 July 2026; doi:10.1038/s41591-026-04491-7In a human clinical trial, repeated administration of an oligonucleotide–siRNA conjugate targeting SOD1 exhibited a favorable safety profile in six patients with SOD1-ALS.
The Download: a useful quantum machine and a record-breaking subsea tunnel
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. PsiQuantum has a plan to make a massive quantum computer out of light The machine that…
What to know about the parasitic diarrhea outbreak
Fallout from the end of ACA subsidies, the FDA CBER acting director "on planet Earth," and more health news from Morning Rounds
STAT+: Medicare Advantage insurers face new bipartisan scrutiny over AI and care denials
Blumenthal, Hawley press UnitedHealth, Humana, CVS for documents related to using AI to deny or delay care.
Opinion: Why we still don’t know what foods are the source of the cyclospora outbreak
“You cannot thin a system, defer the tools that would speed it up, and then wonder why the public is left guessing,” writes epidemiologist Katrine Wallace.
STAT+: Swing Therapeutics acquired by medical VR platform XR Health
Swing Therapeutics, developer of a digital treatment for fibromyalgia, has been acquired by medical virtual reality company XR Health.
Flood of comments on White House grantmaking overhaul is largely negative, analysis shows
An analysis of public comments on a White House proposal to change the way federal contracts and grants are doled out shows widespread opposition
Effect of a Programme Including an AI-enhanced Mobile Application on the Mental Well-being of Young Adolescents in Hong Kong – A Cluster RCT Study
Conditions: Mental Health; Depression and/or Anxiety in the Mild-to-moderate Range Interventions: Behavioral: Control Group :health talk and usual care by school; Device: mobile app group Sponsors: Tung Wah College; Chinese University of Hong Kong; Hong Kong Metropolitan University Not yet…
Clinical Trial of MDMA-Assisted Therapy for Military Service Members With Posttraumatic Stress Disorder
Conditions: PTSD; Post Traumatic Stress Disorder PTSD; Post Traumatic Stress Disorder Interventions: Drug: TREATMENT ARM: Full dose; Drug: CONTROL ARM: Active-controlled Sponsors: U.S. Army Medical Research and Development Command; Resilient Pharmaceuticals; Walter Reed National Military Medical Center; Congressionally Directed Medical…
Safety and Feasibility of FUS Next Generation Dome Helmet (NGDH) to Perform Neuromodulation in Patients With Treatment Refractory Obsessive Compulsive Disorder (OCD)
Conditions: OCD; Obsessive-Compulsive Disorder (OCD); Obsessive-Compulsive Disorder Interventions: Device: Next Generation Dome Helmet (NGDH) Sponsors: Sunnybrook Health Sciences Centre Recruiting
Working Mechanisms and Effectiveness of IV Ketamine-assisted Psychotherapy on Depression in TRD Clients
Conditions: Treatment Resistant Depression Sponsors: Senz; Radboud University Medical Center Recruiting
Oxytocin in the amygdala links social and reward signals to cataplexy in mice
Nature Neuroscience, Published online: 14 July 2026; doi:10.1038/s41593-026-02349-2Loss of orexin neurons in narcolepsy leads to sleepiness and cataplexy episodes, which are most common in social contexts. In a mouse model, an oxytocin-sensitive circuit in the central amygdala is both necessary…
Nonverbal AI-Based Communication Robot for Staff in Disaster-Affected Care Facilities: Exploratory ABAB Intervention Study
Background: Medical and welfare facilities in the Noto region of Japan were severely affected by the 2024 Noto Peninsula earthquake and subsequent torrential rains. Staff working in these facilities were disaster survivors and frontline caregivers with limited psychological support. Nonverbal…
News Feed
Saliva-Based Proteomics Reveals Immune Changes Linked to Oral Cancer Progression
A new single-cell proteomics approach has revealed distinct immune-cell protein signatures associated with oral cancer progression and lymph node involvement. The findings could pave the way for noninvasive saliva tests to help assess disease…
Digitally Assisted Training System for Home-Based Scoliosis Therapy: Proof-of-Concept and Technical Verification Study
Background: Schroth therapy is one of the conservative methods used to treat scoliosis. It includes not only therapeutic exercises in physiotherapy facilities but also concepts for independent training at home. Consistent and correct performance…
Cocreating a Climate and Health Dashboard With Multisector Stakeholders: Qualitative Pilot Study
Background: Climate-related disasters increasingly affect community health, health care access, and disaster preparedness, particularly in disaster-prone Gulf Coast communities. Although climate dashboards have expanded access to environmental data, many function primarily as static repositories…
News
3068 results
ADAR-based DNA adenine base editing with single-nucleotide precision
Nature Biotechnology, Published online: 15 July 2026; doi:10.1038/s41587-026-03228-8Adenosine deaminases acting on RNA (ADARs) have not been previously exploited for DNA adenine base editing in mammals. We developed a single-nucleotide-resolution adenine base editor (snuABE) that uses ADAR and customized guide RNAs…
High numerical aperture confocal volumetric mesoscope reveals mesoscale subcellular dynamics in vivo
Nature Biotechnology, Published online: 15 July 2026; doi:10.1038/s41587-026-03231-zVolumetric mesoscale imaging reveals subcellular immune dynamics in different mammalian organs.
High-fidelity fast fluorescence lifetime imaging by event-based denoising
Nature Biotechnology, Published online: 15 July 2026; doi:10.1038/s41587-026-03222-0Event-based first-photon fluorescence lifetime imaging enables fluorescence lifetime imaging below one photon per pixel.
When caution becomes harm
Nature Medicine, Published online: 15 July 2026; doi:10.1038/s41591-026-04526-zOur pregnant patients deserve accurate conversations about risk.
Multi-omics maps human–pig interactions in extracorporeal liver cross-circulation
Nature Medicine, Published online: 15 July 2026; doi:10.1038/s41591-026-04515-2Spatial and circulating multi-omics of pig-to-human extracorporeal liver cross-circulation reveals an early innate immune response, species-specific complement dynamics and xenograft–platelet interactions, while showing preserved metabolic support even after removal of the native liver.…
Fertilizer scarcity as a failure of global health governance
Nature Medicine, Published online: 15 July 2026; doi:10.1038/s41591-026-04507-2Fertilizer scarcity as a failure of global health governance
Studying vanishing dietary diversity before it is lost: the World Diet Initiative
Nature Medicine, Published online: 15 July 2026; doi:10.1038/s41591-026-04520-5Heritage diets are disappearing as food systems homogenize; their effects on immunity, metabolism and host–microbiome biology remain poorly understood. The World Diet Initiative offers a framework to document heritage diets and investigate their…
Oligonucleotide–siRNA conjugate for SOD1 amyotrophic lateral sclerosis: a phase 1 trial
Nature Medicine, Published online: 15 July 2026; doi:10.1038/s41591-026-04491-7In a human clinical trial, repeated administration of an oligonucleotide–siRNA conjugate targeting SOD1 exhibited a favorable safety profile in six patients with SOD1-ALS.
The Download: a useful quantum machine and a record-breaking subsea tunnel
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. PsiQuantum has a plan to make a massive quantum computer out of light The machine that…
What to know about the parasitic diarrhea outbreak
Fallout from the end of ACA subsidies, the FDA CBER acting director "on planet Earth," and more health news from Morning Rounds
STAT+: Medicare Advantage insurers face new bipartisan scrutiny over AI and care denials
Blumenthal, Hawley press UnitedHealth, Humana, CVS for documents related to using AI to deny or delay care.
Opinion: Why we still don’t know what foods are the source of the cyclospora outbreak
“You cannot thin a system, defer the tools that would speed it up, and then wonder why the public is left guessing,” writes epidemiologist Katrine Wallace.
STAT+: Swing Therapeutics acquired by medical VR platform XR Health
Swing Therapeutics, developer of a digital treatment for fibromyalgia, has been acquired by medical virtual reality company XR Health.
Flood of comments on White House grantmaking overhaul is largely negative, analysis shows
An analysis of public comments on a White House proposal to change the way federal contracts and grants are doled out shows widespread opposition
Effect of a Programme Including an AI-enhanced Mobile Application on the Mental Well-being of Young Adolescents in Hong Kong – A Cluster RCT Study
Conditions: Mental Health; Depression and/or Anxiety in the Mild-to-moderate Range Interventions: Behavioral: Control Group :health talk and usual care by school; Device: mobile app group Sponsors: Tung Wah College; Chinese University of Hong Kong; Hong Kong Metropolitan University Not yet…
Clinical Trial of MDMA-Assisted Therapy for Military Service Members With Posttraumatic Stress Disorder
Conditions: PTSD; Post Traumatic Stress Disorder PTSD; Post Traumatic Stress Disorder Interventions: Drug: TREATMENT ARM: Full dose; Drug: CONTROL ARM: Active-controlled Sponsors: U.S. Army Medical Research and Development Command; Resilient Pharmaceuticals; Walter Reed National Military Medical Center; Congressionally Directed Medical…
Safety and Feasibility of FUS Next Generation Dome Helmet (NGDH) to Perform Neuromodulation in Patients With Treatment Refractory Obsessive Compulsive Disorder (OCD)
Conditions: OCD; Obsessive-Compulsive Disorder (OCD); Obsessive-Compulsive Disorder Interventions: Device: Next Generation Dome Helmet (NGDH) Sponsors: Sunnybrook Health Sciences Centre Recruiting
Working Mechanisms and Effectiveness of IV Ketamine-assisted Psychotherapy on Depression in TRD Clients
Conditions: Treatment Resistant Depression Sponsors: Senz; Radboud University Medical Center Recruiting
Oxytocin in the amygdala links social and reward signals to cataplexy in mice
Nature Neuroscience, Published online: 14 July 2026; doi:10.1038/s41593-026-02349-2Loss of orexin neurons in narcolepsy leads to sleepiness and cataplexy episodes, which are most common in social contexts. In a mouse model, an oxytocin-sensitive circuit in the central amygdala is both necessary…
Nonverbal AI-Based Communication Robot for Staff in Disaster-Affected Care Facilities: Exploratory ABAB Intervention Study
Background: Medical and welfare facilities in the Noto region of Japan were severely affected by the 2024 Noto Peninsula earthquake and subsequent torrential rains. Staff working in these facilities were disaster survivors and frontline caregivers with limited psychological support. Nonverbal…